Research Topics
| Alberto S PappoSummaryAffiliation: Baylor College of Medicine Country: USA Publications
| Collaborators
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Detail Information
Publications
Predictors of outcome in children and adolescents with rhabdomyosarcoma of the trunk--the St Jude Children's Research Hospital experienceChan Hon Chui
Department of Pediatric Surgery, KK Women's and Children's Hospital, Singapore 229 899
J Pediatr Surg 40:1691-5. 2005..CONCLUSION: Tumor size, nodal status, and gross total resection at any time are significant predictors of outcome in truncal rhabdomyosarcoma. Gross tumor excision should be the goal of surgical intervention in this disease...
Pediatric gastrointestinal stromal tumorsAlberto S Pappo
Department of Pediatrics, Texas Children s Cancer Center, 6621 Fannin Street, CC1510 00, Houston, TX 77030, USA
Hematol Oncol Clin North Am 23:15-34, vii. 2009..The generally accepted definition of pediatric GIST is a tumor that is diagnosed at the age of 18 years or younger. This review highlights the clinical features, molecular biology, and clinical management of this rare pediatric entity...
Two consecutive phase II window trials of irinotecan alone or in combination with vincristine for the treatment of metastatic rhabdomyosarcoma: the Children's Oncology GroupAlberto S Pappo
Texas Children s Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA
J Clin Oncol 25:362-9. 2007....
Administration of high-dose interleukin-2 in a 2-year-old with metastatic melanomaM Brooke Bernhardt
Department of Pharmacy, Texas Children s Hospital, Houston, Texas 77030, USA
Pediatr Blood Cancer 53:1346-8. 2009..This report describes our experience with the use of high-dose interleukin 2 (aldesleukin, IL-2) in a 2-year-old child with metastatic melanoma and describes our approach for the administration of this agent to young patients...
Phase II trial of neoadjuvant vincristine, ifosfamide, and doxorubicin with granulocyte colony-stimulating factor support in children and adolescents with advanced-stage nonrhabdomyosarcomatous soft tissue sarcomas: a Pediatric Oncology Group StudyAlberto S Pappo
The Hospital for Sick Children, 555 University Ave, Toronto, ON, M5G1X8, Canada
J Clin Oncol 23:4031-8. 2005..To describe the response rate and survival of children and adolescents with unresected or metastatic nonrhabdomyosarcomatous soft tissue sarcomas (NRSTS) treated with vincristine, ifosfamide, and doxorubicin...
Concomitant administration of vincristine, doxorubicin, cyclophosphamide, ifosfamide, and etoposide for high-risk sarcomas: the St. Jude Children's Research Hospital experienceFariba Navid
Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, Tennessee 38105 2794, USA
Cancer 106:1846-56. 2006..Vincristine, doxorubicin, cyclophosphamide, ifosfamide, and etoposide are highly effective against pediatric sarcomas. The authors investigated the feasibility of administering these agents concomitantly within a defined period...
Treatment of Ewing sarcoma family of tumors: current status and outlook for the futureCarlos Rodriguez-Galindo
Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
Med Pediatr Oncol 40:276-87. 2003..Our current understanding in the biology and treatment of ESFT suggests that a more rational approach to the development of risk-adapted therapy should be undertaken...
Pooled analysis of phase II window studies in children with contemporary high-risk metastatic rhabdomyosarcoma: a report from the Soft Tissue Sarcoma Committee of the Children's Oncology GroupJoanne J Lager
Duke University Medical Center, Durham, NC 27710, USA
J Clin Oncol 24:3415-22. 2006..Finally, these results provide a rationale for incorporating ifosfamide, etoposide, doxorubicin, and topoisomerase I poisons in future trials of high-risk metastatic rhabdomyosarcoma...
Analysis of prognostic factors in patients with nonmetastatic rhabdomyosarcoma treated on intergroup rhabdomyosarcoma studies III and IV: the Children's Oncology GroupJane L Meza
Department of Preventive and Societal Medicine, 984350 Nebraska Medical Center, Omaha, NE 68198 4350, USA
J Clin Oncol 24:3844-51. 2006..The outcome for localized rhabdomyosarcoma (RMS) or undifferentiated sarcoma (UDS) is affected by age, histology, primary anatomic site, extent of disease, and therapy...
Prognostic factors and clinical outcomes in children and adolescents with metastatic rhabdomyosarcoma--a report from the Intergroup Rhabdomyosarcoma Study IVJohn C Breneman
Children s Hospital Medical Center, Division of Radiation Oncology, Cincinnati, OH 45219 0757, USA
J Clin Oncol 21:78-84. 2003..To identify risk factors associated with outcomes in children with metastatic rhabdomyosarcoma (RMS) treated on the fourth Intergroup Rhabdomyosarcoma Study (IRS-IV)...
New drugs for the treatment of metastatic or refractory soft tissue sarcomas in childrenAbha A Gupta
Hospital for Sick Children, Division of Hematology Oncology, Toronto, Canada
Future Oncol 2:675-85. 2006..The progress to date and the tools used in the treatment of advanced pediatric sarcomas will be summarized in this review...
Reducing irinotecan-associated diarrhea in childrenLars M Wagner
Division of Pediatric Hematology Oncology, Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA
Pediatr Blood Cancer 50:201-7. 2008..This approach is feasible in children and allows for tolerance of higher doses of protracted irinotecan...
Preradiation chemotherapy with methotrexate, cisplatin, 5-fluorouracil, and leucovorin for pediatric nasopharyngeal carcinomaCarlos Rodriguez-Galindo
Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
Cancer 103:850-7. 2005..Chemotherapy may help to decrease the radiotherapy dose and limit the side effects of local therapies. However, little is known regarding the chemosensitivity of NPC tumors in pediatric patients...
Remote intrapulmonary spread of recurrent respiratory papillomatosis with malignant transformationSherri L Katz
Department of Pediatrics, Hospital for Sick Children, Toronto, Ontario, Canada
Pediatr Pulmonol 39:185-8. 2005..Treatment options for intrapulmonary spread have shown limited success. We describe a case of recurrent respiratory papillomatosis with extensive parenchymal involvement and adenosquamous carcinoma in a 14-year-old girl...
Late events occurring five years or more after successful therapy for childhood rhabdomyosarcoma: a report from the Soft Tissue Sarcoma Committee of the Children's Oncology GroupLillian Sung
The Division of Hematology/Oncology, Hospital for Sick Children, 555 University Avenue, Toronto, Ont, M5G 1X8, Canada
Eur J Cancer 40:1878-85. 2004..Late events after successful treatment for rhabdomyosarcoma occur in 9%. Those with advanced disease and large primary tumours have the highest risk of late events...
Brain metastases of malignant germ cell tumors in children and adolescentsSheri L Spunt
Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
Cancer 101:620-6. 2004..Brain metastases of pediatric germ cell tumors are uncommon, and there is limited information regarding their incidence, clinical presentation, response to treatment, and influence on survival...
Perianal rhabdomyosarcoma presenting as a perirectal abscess: A report of 11 casesD Ashley Hill
Department of Pathology, St Jude Children's Research Hospital and University of Tennessee, Memphis TN, USA
J Pediatr Surg 37:576-81. 2002....
C-kit expression in pediatric solid tumors: a comparative immunohistochemical studyBrandon E Smithey
Department of Pathology, University of Tennessee Medical Center, Memphis, Tennessee, USA
Am J Surg Pathol 26:486-92. 2002..Tumors with strong, diffuse staining for c-kit in a pattern similar to gastrointestinal stromal tumor may represent suitable targets for new therapeutic agents...
Treatment of refractory osteosarcoma with fractionated cyclophosphamide and etoposideCarlos Rodriguez-Galindo
Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, Tennessee 38105 2794, USA
J Pediatr Hematol Oncol 24:250-5. 2002..By identifying new chemotherapeutic strategies, the outcome of these patients can be improved and the toxicity of treatment regimens decreased...
Clinical features and outcome of initially unresected nonmetastatic pediatric nonrhabdomyosarcoma soft tissue sarcomaSheri L Spunt
Department of Hematology Oncology, St Jude Children s Research Hospital, University of Tennessee College of Medicine, 332 N Lauderdale Street, Memphis, TN 38105 2794, USA
J Clin Oncol 20:3225-35. 2002..To describe the clinical features, response to therapy, and outcome of pediatric patients with initially unresected nonmetastatic nonrhabdomyosarcoma soft tissue sarcoma (NRSTS)...
A chemosensitive pediatric extraosseous osteosarcoma: case report and review of the literatureKaren Wodowski
Departments of Hematology/ Oncology, St. Jude's Research Hospital, 332 N. Lauderdale Street, Memphis, TN 38105-2794, USA
J Pediatr Hematol Oncol 25:73-7. 2003..Children with extraosseous osteosarcoma may have a more favorable response to treatment than adults; thus, a curative approach using combined modality therapy appears warranted...
Treatment of localized nonorbital, nonparameningeal head and neck rhabdomyosarcoma: lessons learned from intergroup rhabdomyosarcoma studies III and IVAlberto S Pappo
Department of Pediatrics, Hospital for Sick Children, Toronto, Ontario, Canada
J Clin Oncol 21:638-45. 2003..The characteristics and clinical outcomes of children and adolescents with localized nonorbital, nonparameningeal head and neck rhabdomyosarcoma (RMS) treated on national protocols from the Intergroup Rhabdomyosarcoma Group are reported...
Malignant fibrous histiocytoma and other fibrohistiocytic tumors in pediatric patients: the St. Jude Children's Research Hospital experienceNajat C Daw
Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
Cancer 97:2839-47. 2003..In the current study, the authors reviewed their institutional experience with these tumors to characterize their clinical features in pediatric patients and assess the impact of surgical resection on outcome...
Orbital inflammatory syndromes with systemic involvement may mimic metastatic diseaseMelanie R Foley
Department of Ophthalmology, University of Tennessee Health Science Center, Memphis, Tennessee, USA
Ophthal Plast Reconstr Surg 19:324-7. 2003..Accurate diagnosis requires careful clinical and pathologic examinations...
Metastatic rhabdomyosarcoma: a retrospective review of patients treated at the hospital for sick children between 1989 and 1999Brent A Williams
Division of Hematology/Oncology, Department of Pediatrics, The Hospital for Sick Children, University of Toronto, Toronto, Canada
J Pediatr Hematol Oncol 26:243-7. 2004....
Neurofibromatosis in children with Rhabdomyosarcoma: a report from the Intergroup Rhabdomyosarcoma study IVLillian Sung
Division of Hematology/Oncology, Hospital for Sick Children, Toronto, Ontario, Canada
J Pediatr 144:666-8. 2004..Among 1025 eligible patients, 5 (0.5 %) had NF1. Three children had relapses, two of whom died of progressive disease. Patients with NF1 and rhabdomyosarcoma should be treated with intensive contemporary therapy protocols...
Survival after recurrence of Ewing tumors: the St Jude Children's Research Hospital experience, 1979-1999Carlos Rodriguez-Galindo
Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
Cancer 94:561-9. 2002..Despite improved therapies, 30-40% of patients with Ewing tumors (ET) experience recurrence and have a poor prognosis. The authors analyzed factors prognostic of survival in patients with recurrent ET...
