Roberta Ness

..Few studies have examined methods of contraception, beyond oral contraceptives (OCs) and tubal ligation, in relation to ovarian cancer risk...

..Broader mastery of many of these tools, particularly when used in combination, has provided our students with a powerful device for enhancing innovation...

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..40 OD units) were 0.6 (95% CI 0.4-0.9). These data do not support our earlier finding of elevated titers for antibodies to C. trachomatis among women with ovarian cancer...

..We sought to examine the relationship between the use of estrogen plus testosterone (E + T) therapy (esterified estradiol plus methyltestosterone) and the occurrence of breast cancer...

..g., genomics, comparative effectiveness in therapeutics), and factors shaping human health (e.g., increasing globalism, the environment, disease and lifestyle, demographics, infectious disease)...

..The need to remove major barriers to human health research cannot be forgotten. At risk is America's progress in finding solutions to our most pressing health concerns...

..Eventually, the chair must know when to quit and how to quit well. Although being chair is demanding and sometimes difficult, it is a position that can be rewarding to both the individual and the department...

..Because factors such as oral contraceptive (OC), hormone therapy (HT), and parity may affect weight and hormone levels, the associations were examined in women with and without these characteristics...

..As women progress through menopause, they experience changes in sexual functioning that are multifactorial, likely encompassing biological, psychological, and social domains...

..Our aims were to ensure full disclosure to donors and recipients of the risks and benefits of this procedure in a large University center and to help explain reporting inconsistencies...

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..09) in ovarian cancer risk associated with CHSP60-1 but not with CHSP60-2, CHSP60-3, or CHSP10. These data suggest that past or chronic persistent infection with chlamydia may be a risk factor for ovarian cancer...

..Public health policy to reduce sodium intake in the United States would have significant cost-savings, far greater than the cost of intervention, and would also result in a significant gain in quality-adjusted life years...

..To assess the effect of raloxifene compared with placebo on sexual function in older postmenopausal women undergoing therapy for the treatment of osteoporosis...

..Among women with pelvic inflammatory disease (PID), we assessed the associations among antibodies to Chlamydia trachomatis elementary bodies (EB), antibodies to chlamydia heat shock protein (Chsp60), rates of pregnancy, and PID recurrence...

..The objective of this study was to assess in prospective data whether bacterial vaginosis (BV) is associated with gonococcal/chlamydial cervicitis...

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..We investigated whether the odds ratios for ovarian cancer that were associated with oral contraceptive use, childbearing, hysterectomy, and tubal ligation differ among women with and without endometriosis...

..The association between cigarette smoking and ovarian cancer may vary according to the histologic type of tumor...

..Mediating factors may reflect endogenous hormone levels, OC metabolism, or OC bioactivity...

..To assess prediction strategies for pelvic inflammatory disease (PID)...

..These data do not support an association between douching and development of PID or gonococcal/chlamydial genital infection among predominantly young, African-American women...

..Although a handful of studies have shown that monotherapies for PID achieve high rates of clinical cure, the efficacy of these regimens in treating anaerobic PID and in preventing adverse reproductive sequelae is not fully elucidated...

..Anecdotal reports suggest that the Health Insurance Portability and Accountability Act Privacy Rule (HIPAA Privacy Rule) may be affecting health research in the United States...

..Obesity eliminated the inverse association between smoking and preeclampsia but did not substantially alter the positive association between smoking and SGA. A possible unifying biologic explanation is discussed in this paper...

..The characteristics of nongonococcal, nonchlamydial PID have not been well described. Our objective was to examine the characteristics of Mycoplasma genitalium infection among women with clinically suspected PID...

..This analysis shows the importance of consortia, like the OCAC, in either confirming or refuting the validity of putative findings in studies with smaller sample sizes. (Cancer Epidemiol Biomarkers Prev 2008;17(12):3567-72)...

..Inflammation was a more important mediator than triglycerides. These findings suggest that approximately one third of the total effect of body mass index on preeclampsia risk is mediated through inflammation and triglyceride levels...

..80, 95% CI: 0.44, 1.47). These data do not support an independent association between incomplete pregnancies, either spontaneous or induced, and ovarian cancer risk...

..We investigated associations between HLA class II DQ alleles, chlamydial and gonococcal cervicitis, endometritis, and infertility among women with pelvic inflammatory disease (PID)...

..We investigated the association between endometritis and reproductive morbidity...

..049). No significant differences in EOC risk were observed for other HRT formulations. CONCLUSIONS: Our results did not suggest any consistent pattern of altered risk for EOC and the overall use of HRT by specific formulations of HRT...

..10, 2.71) and unknown cause of infertility (OR = 1.19, 95% CI: 1.00, 1.40) increased cancer risk. These data suggest a role for specific biologic causes of infertility, but not for fertility drugs in overall risk for ovarian cancer...

..We hypothesize that nulliparous women will have more dissatisfaction with childbearing choices and more negative attitudes toward menopause but will experience fewer menopausal symptoms...

..The androgenic medication, danazol, and the antiandrogenic medications, leuprolide and nafarelin, are commonly used in the treatment of endometriosis. We assessed the associations between the use of these medications and ovarian cancer...

..Consistent condom use (about 60% of encounters) at baseline also reduced these risks, after adjustment for confounders, by 30% to 60%. Self-reported persistent and consistent condom use was associated with lower rates of PID sequelae...

..Research comparing sequelae development by differing antimicrobial regimens is extremely limited, but will ultimately shape future treatment guidelines...

..To determine whether parity is associated with increased risk of cardiovascular disease (CVD) after accounting for perinatal complications...

..CONCLUSIONS: The disturbing rates of time interval adherence, even after hospitalization, suggest the need to determine the effectiveness of antibiotic regimens involving shorter courses and longer dosing intervals...

..To examine dose-response relationships between the cumulative number of months women lactated and postmenopausal risk factors for cardiovascular disease...

..The results indicate that some metabolic factors together with inflammation may be related to the risk of sPTB...

..As the consequences of Mycoplasma genitalium in pregnant women are unknown, we examined the relationship between prenatal M. genitalium infection and SAB...

..trachomatis infection; better tools to measure PID and tubal damage; and studies on the natural history of repeated chlamydial infections are needed...

..Black women are more likely to have bacterial vaginosis (BV) than are non-Hispanic white women. We examined whether this disparity can be explained by racial differences in known BV risk factors...

..The authors investigated whether OC efficacy might differ according to androgenicity by using data from a large, population-based, case-control study (the Steroid Hormones and Reproductions [SHARE] Study)...

..Utilities for PID could have important implications on the cost-effectiveness of interventions to prevent and manage this disease...

..Breast density is a strong risk factor for breast cancer, but little is known about factors associated with breast density in women over 70...

..We sought to determine whether offspring gender, which differentially alters maternal hormonal milieu, may be associated with maternal ovarian cancer risk...

..The purpose of this study was to examine the relationship between cytokine genotypes and preeclampsia...

..Moreover, treatments for endometriosis may require consideration of the impact on long-term cancer risk...

..Testing of urine samples is noninvasive and could overcome several barriers to screening for chlamydial and gonococcal infections, but most test samples are obtained directly from the cervix or urethra...

..However, the latter condition occurs without maternal vascular disease...

..We detected M genitalium in 7 (14%) of the women tested: 6 (12%) in cervical specimens and 4 (8%) in endometrial specimens. We conclude that M genitalium is prevalent in the endometrium of women with nongonococcal, nonchlamydial PID...

..69; 95% CI, 0.44-1.10). CONCLUSIONS: A range of demographic, clinical, historical, and behavioral factors predict CPP after PID...

..Study results indicate lower rates of severe preterm births and extreme SGA in women who report periconceptional vitamin use, although these should be considered cautiously until replicated...

..To identify the value that women with pelvic inflammatory disease (PID) assign to the health impact of future infertility...

..A home testing program could be cost saving, depending on whether changes in clinic testing frequency occur when home testing is available...

..CONCLUSION: This study suggests that optimized chemoresponse assays may be beneficial in selecting specific chemotherapy regimens for women with ovarian cancer...

..Previous studies have been inconsistent with regard to whether condom use is associated with bacterial vaginosis. We evaluated this association using case-crossover analyses...

..The hypothesis that immune hyperresponsiveness limits reproductive capacity suggests many avenues for research...

..We assessed whether outpatient is as effective as inpatient treatment in relevant age, race, and clinical subgroups of women with PID...

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..Prepregnancy overweight is a risk factor for mild preeclampsia and mild transient hypertension of pregnancy. Its association with severe subtypes of these disorders has received less attention...

..To examine alcohol consumption as a risk factor for epithelial ovarian cancer according to tumor histology...

..Few data are available on the prevalence of and risk factors for sexually transmitted diseases (STDs) other than HIV in Brazil...

..To evaluate the relationship between douching and bacterial vaginosis (BV) among women with and without prior abnormal vaginal flora...

..Differences in the frequency and severity of preeclampsia in African Americans cannot be explained by higher leptin concentrations...

..AMI following non-penetrating injury has been shown to carry significant morbidity and mortality...

..This study will determine whether a home screening strategy for bacterial STD's would enhance compliance with screening recommendations; such a strategy could contribute to elimination of STD's at reduced societal cost. ..

..The presence of risk markers at an early age, specifically an age wherein markers of cardiovascular risk are typically not measured, may allow for implementation of early preventative interventions. ..

..In particular, NSAID use may prove to be a potentially important chemopreventative for this often-fatal disease. ..

..The presence of risk markers at an early age, specifically an age wherein markers of cardiovascular risk are typically not measured, may allow for implementation of early preventative interventions. ..

..We gain great efficiency in the use of the extensive resources and excellent follow-up success within the PEACH cohort. ..

..Given the paucity of information regarding the relationship between douching and reproductive outcomes, the proposed study is imperative in order to direct future public health recommendations. ..