Research Topics
| FREDERICK MOELLERSummaryAffiliation: Baylor College of Medicine Country: USA Publications
Research Grants
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Detail Information
Publications
Psychiatric aspects of impulsivityF G Moeller
Department of Psychiatry and Behavioral Sciences, University of Texas Houston Health Science Center, 77030, USA
Am J Psychiatry 158:1783-93. 2001..The authors discuss the relationship of impulsivity to psychiatric disorders and present selected hypotheses regarding the reasons for these relationships...
Use of stimulants to treat cocaine and methamphetamine abuseF Gerard Moeller
Department of Psychiatry and Behavioral Sciences, University of Texas Health Science Center at Houston, 1300 Moursund, Houston, TX 77030, USA
Curr Psychiatry Rep 10:385-91. 2008..It is hoped that these medications will provide safe, effective treatment for cocaine and methamphetamine dependence, but more research on this topic is needed...
Diffusion tensor imaging in MDMA users and controls: association with decision makingF Gerard Moeller
Department of Psychiatry and Behavioral Sciences, University of Texas Health Science Center, Houston, Texas 77030, USA
Am J Drug Alcohol Abuse 33:777-89. 2007..There was a significant positive correlation between lambda(1) in the rostral body of the corpus callosum and advantageous choices on the IGT. Further research on the etiology of these findings is warranted...
Diffusion tensor imaging eigenvalues: preliminary evidence for altered myelin in cocaine dependenceF Gerard Moeller
Department of Psychiatry and Behavioral Sciences, University of Texas Health Science Center Houston, 1300 Moursund, Houston, TX 77030, USA
Psychiatry Res 154:253-8. 2007....
Reduced anterior corpus callosum white matter integrity is related to increased impulsivity and reduced discriminability in cocaine-dependent subjects: diffusion tensor imagingFrederick Gerard Moeller
Department of Psychiatry and Behavioral Sciences, University of Texas Health Science Center at Houston, Houston, TX 77030, USA
Neuropsychopharmacology 30:610-7. 2005....
P300 event-related potential amplitude and impulsivity in cocaine-dependent subjectsF Gerard Moeller
Department of Psychiatry and Behavioral Sciences, University of Texas Health Science Center Houston, Moursund, Houston, Texas, USA
Neuropsychobiology 50:167-73. 2004..This study supports the hypothesis that the basic neurophysiology responsible for the P300 amplitude in cocaine-dependent individuals is associated with impulsivity independent of a history of childhood conduct disorder symptoms...
Functional MRI study of working memory in MDMA usersF Gerard Moeller
Department of Psychiatry and Behavioral Sciences, University of Texas Health Science Center Houston, 1300 Moursund, Houston, TX 77030, USA
Psychopharmacology (Berl) 177:185-94. 2004..Similarly, behavioral studies in human MDMA users regularly find abnormalities in memory, mood, and impulse control. However, studies of brain function using brain imaging in MDMA users have been less consistent...
Increased impulsivity in cocaine dependent subjects independent of antisocial personality disorder and aggressionF Gerard Moeller
Department of Psychiatry and Behavioral Sciences, University of Texas Health Science Center Houston, 1300 Moursund, Houston, TX 77030, USA
Drug Alcohol Depend 68:105-11. 2002..This study supports the hypothesis that the increased impulsivity as measured by the BIS-11 in cocaine dependent individuals is not exclusively due to concomitant increases in aggression or ASPD...
The impact of impulsivity on cocaine use and retention in treatmentF G Moeller
Department of Psychiatry and Behavioral Sciences, University of Texas Houston Health Science Center, Houston, TX 77030, USA
J Subst Abuse Treat 21:193-8. 2001..This study shows that impulsivity is a significant predictor of cocaine use and treatment retention, and suggests the need for targeting impulsivity in cocaine dependence treatment...
Working memory fMRI activation in cocaine-dependent subjects: association with treatment responseF Gerard Moeller
Department of Psychiatry and Behavioral Sciences, University of Texas Health Science Center at Houston, 1300 Moursund, Houston, TX 77030, United States
Psychiatry Res 181:174-82. 2010..Subjects with pretreatment thalamic deactivation showed the poorest treatment response, possibly related to thalamic involvement in mesocortical and mesolimbic dopamine projections...
Impulsivity and BOLD fMRI activation in MDMA users and healthy control subjectsIgnacio H Valdes
Department of Psychiatry and Behavioral Sciences, University of Texas Health Science Center at Houston, 1300 Moursund, Houston, TX 77030, USA
Psychiatry Res 147:239-42. 2006..A significant correlation between BIS scores and DLPFC activation was found, supporting a role for the DLPFC in BIS-measured impulsivity...
Research Grants
- Serotonin, Impulsivity, and Substance AbuseFREDERICK MOELLER; Fiscal Year: 2007..The research plan draws heavily from R01DA15345, and the competing renewal of R01DA08425, on which the author is the principal investigator. ..
- Scientific Meeting of ISRIFREDERICK MOELLER; Fiscal Year: 2005..Through all sessions, the planning committee will strive for a balance of attendance and participation from junior investigators, women, trainees, and underrepresented populations through travel awards for these groups. ..
- Serotonin, Drug Use and MDMA Induced DeficitsFREDERICK MOELLER; Fiscal Year: 2005..Specific Aim 3: To determine whether neurobehavioral deficits seen in heavy MDMA users are related to serotonergic function as measured by a mCPP neuroendocrine challenge in these subjects. ..
- SEROTONIN, IMPULSIVITY AND COCAINE DEPENDENCE TREATMENTFREDERICK MOELLER; Fiscal Year: 2004..Aim 3. To measure impulsivity in subjects undergoing treatment for cocaine dependence using laboratory tasks to determine if changes in impulsivity predict response to treatment for cocaine dependence. ..
