Eugenia Mileykovskaya

Summary

Affiliation: Baylor College of Medicine
Country: USA

Publications

  1. ncbi Arrangement of the respiratory chain complexes in Saccharomyces cerevisiae supercomplex III2IV2 revealed by single particle cryo-electron microscopy
    Eugenia Mileykovskaya
    Department of Biochemistry and Molecular Biology, University of Texas Houston Medical School, Houston, Texas 77030, USA
    J Biol Chem 287:23095-103. 2012
  2. ncbi Cardiolipin membrane domains in prokaryotes and eukaryotes
    Eugenia Mileykovskaya
    Department of Biochemistry and Molecular Biology, University of Texas Medical School, Houston, TX 77030, USA
    Biochim Biophys Acta 1788:2084-91. 2009
  3. ncbi Phosphatidic acid and N-acylphosphatidylethanolamine form membrane domains in Escherichia coli mutant lacking cardiolipin and phosphatidylglycerol
    Eugenia Mileykovskaya
    Department of Biochemistry and Molecular Biology, University of Texas, Medical School, Houston, TX 77030, USA
    J Biol Chem 284:2990-3000. 2009
  4. ncbi Subcellular localization of Escherichia coli osmosensory transporter ProP: focus on cardiolipin membrane domains
    Eugenia Mileykovskaya
    Department of Biochemistry and Molecular Biology, University of Texas Houston Medical School, Houston, TX 77225, USA
    Mol Microbiol 64:1419-22. 2007
  5. ncbi Cardiolipin in energy transducing membranes
    E Mileykovskaya
    Department of Biochemistry and Molecular Biology, University of Texas Houston, Medical School, Houston, TX 77030, USA
    Biochemistry (Mosc) 70:154-8. 2005
  6. ncbi Cardiolipin is essential for organization of complexes III and IV into a supercomplex in intact yeast mitochondria
    Mei Zhang
    Department of Biochemistry and Molecular Biology, University of Texas-Houston Medical School, 77225, USA
    J Biol Chem 280:29403-8. 2005
  7. ncbi Gluing the respiratory chain together. Cardiolipin is required for supercomplex formation in the inner mitochondrial membrane
    Mei Zhang
    Department of Biochemistry and Molecular Biology, University of Texas Medical School, Houston 77225, USA
    J Biol Chem 277:43553-6. 2002
  8. ncbi Cardiolipin is not required to maintain mitochondrial DNA stability or cell viability for Saccharomyces cerevisiae grown at elevated temperatures
    Mei Zhang
    Department of Biochemistry and Molecular Biology, University of Texas-Houston Medical School, Houston, Texas 77030, USA
    J Biol Chem 278:35204-10. 2003
  9. ncbi Adenine nucleotide-dependent regulation of assembly of bacterial tubulin-like FtsZ by a hypermorph of bacterial actin-like FtsA
    Tushar K Beuria
    Department of Microbiology and Molecular Genetics, University of Texas Medical School, Houston, Texas 77030, USA
    J Biol Chem 284:14079-86. 2009
  10. ncbi Effects of phospholipid composition on MinD-membrane interactions in vitro and in vivo
    Eugenia Mileykovskaya
    Department of Biochemistry, The University of Texas Medical School, Houston, Texas 77030, USA
    J Biol Chem 278:22193-8. 2003

Collaborators

Detail Information

Publications20

  1. ncbi Arrangement of the respiratory chain complexes in Saccharomyces cerevisiae supercomplex III2IV2 revealed by single particle cryo-electron microscopy
    Eugenia Mileykovskaya
    Department of Biochemistry and Molecular Biology, University of Texas Houston Medical School, Houston, Texas 77030, USA
    J Biol Chem 287:23095-103. 2012
    ..The supercomplex contains about 50 molecules of cardiolipin (CL) with a fatty acid composition identical to that of the inner membrane CL pool, consistent with CL-dependent stabilization of the supercomplex...
  2. ncbi Cardiolipin membrane domains in prokaryotes and eukaryotes
    Eugenia Mileykovskaya
    Department of Biochemistry and Molecular Biology, University of Texas Medical School, Houston, TX 77030, USA
    Biochim Biophys Acta 1788:2084-91. 2009
    ..Hypotheses on CL-dependent dynamic re-organization of the respiratory chain in response to changes in metabolic states and CL dynamic re-localization in mitochondria during the apoptotic response are briefly addressed...
  3. ncbi Phosphatidic acid and N-acylphosphatidylethanolamine form membrane domains in Escherichia coli mutant lacking cardiolipin and phosphatidylglycerol
    Eugenia Mileykovskaya
    Department of Biochemistry and Molecular Biology, University of Texas, Medical School, Houston, TX 77030, USA
    J Biol Chem 284:2990-3000. 2009
    ..The findings support the proposed role for anionic phospholipids in organizing amphitropic cell division proteins at specific sites on the membrane surface...
  4. ncbi Subcellular localization of Escherichia coli osmosensory transporter ProP: focus on cardiolipin membrane domains
    Eugenia Mileykovskaya
    Department of Biochemistry and Molecular Biology, University of Texas Houston Medical School, Houston, TX 77225, USA
    Mol Microbiol 64:1419-22. 2007
    ..The properties of cardiolipin domains employed in creating a specific environment for structural organization and function of membrane protein complexes are also discussed...
  5. ncbi Cardiolipin in energy transducing membranes
    E Mileykovskaya
    Department of Biochemistry and Molecular Biology, University of Texas Houston, Medical School, Houston, TX 77030, USA
    Biochemistry (Mosc) 70:154-8. 2005
    ..The role of cardiolipin in higher order organization of components of the mitochondrial respiratory chain revealed by a combined molecular genetic and biochemical approach is described...
  6. ncbi Cardiolipin is essential for organization of complexes III and IV into a supercomplex in intact yeast mitochondria
    Mei Zhang
    Department of Biochemistry and Molecular Biology, University of Texas-Houston Medical School, 77225, USA
    J Biol Chem 280:29403-8. 2005
    ..The results demonstrate that cardiolipin is essential for association of complexes III and IV into a supercomplex in intact yeast mitochondria...
  7. ncbi Gluing the respiratory chain together. Cardiolipin is required for supercomplex formation in the inner mitochondrial membrane
    Mei Zhang
    Department of Biochemistry and Molecular Biology, University of Texas Medical School, Houston 77225, USA
    J Biol Chem 277:43553-6. 2002
    ..These results strongly indicate that CL plays a central role in higher order organization of components of the respiratory chain of mitochondria...
  8. ncbi Cardiolipin is not required to maintain mitochondrial DNA stability or cell viability for Saccharomyces cerevisiae grown at elevated temperatures
    Mei Zhang
    Department of Biochemistry and Molecular Biology, University of Texas-Houston Medical School, Houston, Texas 77030, USA
    J Biol Chem 278:35204-10. 2003
    ..These results suggest that all phenotypes reported for cells carrying the his3 Delta 200 allele and lacking CL should be re-evaluated...
  9. ncbi Adenine nucleotide-dependent regulation of assembly of bacterial tubulin-like FtsZ by a hypermorph of bacterial actin-like FtsA
    Tushar K Beuria
    Department of Microbiology and Molecular Genetics, University of Texas Medical School, Houston, Texas 77030, USA
    J Biol Chem 284:14079-86. 2009
    ..These results indicate that a bacterial actin, when activated by adenine nucleotides, can modify the length distribution of bacterial tubulin polymers, analogous to the effects of actin-depolymerizing factor/cofilin on F-actin...
  10. ncbi Effects of phospholipid composition on MinD-membrane interactions in vitro and in vivo
    Eugenia Mileykovskaya
    Department of Biochemistry, The University of Texas Medical School, Houston, Texas 77030, USA
    J Biol Chem 278:22193-8. 2003
    ..These results suggest that MinD has a preference for anionic phospholipids and that MinD oscillation behavior, and therefore cell division site selection, may be regulated by membrane phospholipid composition...
  11. ncbi Diversity and versatility of lipid-protein interactions revealed by molecular genetic approaches
    William Dowhan
    Department of Biochemistry and Molecular Biology, University of Texas Houston, Medical School, Suite 6 200, 6431 Fannin St, Houston, TX, 77030, USA
    Biochim Biophys Acta 1666:19-39. 2004
    ..The evidence is summarized for the involvement of anionic lipid-enriched domains in the organization of amphitropic proteins on the membrane surface into molecular machines involved in DNA replication and cell division...
  12. ncbi Role of membrane lipids in bacterial division-site selection
    Eugenia Mileykovskaya
    Department of Biochemistry and Molecular Biology, University of Texas-Houston, Medical School, 6431 Fannin St, Suite 6.200, Houston, TX 77030, USA
    Curr Opin Microbiol 8:135-42. 2005
    ....
  13. ncbi Lipids in the assembly of membrane proteins and organization of protein supercomplexes: implications for lipid-linked disorders
    Mikhail Bogdanov
    Department of Biochemistry and Molecular Biology, University of Texas Houston, Houston, TX 77030, USA
    Subcell Biochem 49:197-239. 2008
    ....
  14. ncbi Lack of mitochondrial anionic phospholipids causes an inhibition of translation of protein components of the electron transport chain. A yeast genetic model system for the study of anionic phospholipid function in mitochondria
    D B Ostrander
    Department of Biochemistry and Molecular Biology, University of Texas Medical School, Houston, TX 77225, USA
    J Biol Chem 276:25262-72. 2001
    ..Thus, the molecular basis for the lack of mitochondrial function in pgs1Delta cells is the failure to translate gene products essential to the electron transport chain...
  15. ncbi Isolation and characterization of the gene (CLS1) encoding cardiolipin synthase in Saccharomyces cerevisiae
    S C Chang
    Department of Biochemistry and Molecular Biology, University of Texas Medical School, Houston, Texas 77225, USA
    J Biol Chem 273:14933-41. 1998
    ..These results definitively identify the gene encoding the CL synthase of yeast...
  16. ncbi A hypothesis to explain division site selection in Escherichia coli by combining nucleoid occlusion and Min
    Vic Norris
    Assemblages Moléculaires Modélisation et Imagerie SIMS, FRE CNRS 2829, Faculte des Sciences and Techniques, Universite de Rouen, 76821 Mont Saint Aignan, France
    FEBS Lett 561:3-10. 2004
    ....
  17. ncbi Monoglucosyldiacylglycerol, a foreign lipid, can substitute for phosphatidylethanolamine in essential membrane-associated functions in Escherichia coli
    Malin Wikström
    Department of Biochemistry and Biophysics, Stockholm University, Sweden
    J Biol Chem 279:10484-93. 2004
    ..The reduced dependence on Mg(2+) and lack of correction by high monovalent salts strongly support the essential nature of the NB properties of MGlcDAG...
  18. ncbi Toward a hyperstructure taxonomy
    Vic Norris
    Department of Science, University of Rouen, 76821 Mont Saint Aignan Cedex, France
    Annu Rev Microbiol 61:309-29. 2007
    ..Hence a taxonomy by trajectory may be desirable. Finally, we suggest that working toward a taxonomy based on speculative interactions between hyperstructures promises most insight into life at this level...
  19. ncbi Functional taxonomy of bacterial hyperstructures
    Vic Norris
    Department of Science, University of Rouen, 76821 Mont Saint Aignan Cedex, France
    Microbiol Mol Biol Rev 71:230-53. 2007
    ..We propose principles for classifying these hyperstructures and finally illustrate how thinking in terms of hyperstructures may lead to a different vision of the bacterial cell...
  20. ncbi Behaviour of bacterial division protein FtsZ under a monolayer with phospholipid domains
    Céline Lafontaine
    Polymeres, Biopolymères, Membranes, UMR 6522 CNRS, Universite de Rouen, UFR des Sciences, 76821, Mont Saint Aignan Cedex, France
    Biochim Biophys Acta 1768:2812-21. 2007
    ..After several hours, with or without GTP, FtsZ assembled into large aggregates at the domain interface. We suggest that the GTP-induced polymerization of FtsZ is coupled to the association of FtsZ protofilaments with domain interfaces...