AMY LYNN MCGUIRE

Summary

Affiliation: Baylor College of Medicine
Country: USA

Publications

  1. doi request reprint Confidentiality, privacy, and security of genetic and genomic test information in electronic health records: points to consider
    Amy L McGuire
    From the 1Center for Medical Ethics and Health Policy, Baylor College of Medicine, Houston, TX 77030, USA
    Genet Med 10:495-9. 2008
  2. pmc "Snake-oil," "quack medicine," and "industrially cultured organisms:" biovalue and the commercialization of human microbiome research
    Melody J Slashinski
    Center for Medical Ethics and Health Policy, Baylor College of Medicine, Houston, TX 77030, USA
    BMC Med Ethics 13:28. 2012
  3. pmc Perspectives on human microbiome research ethics
    Amy L McGuire
    Baylor College of Medicine, Houston, TX, USA
    J Empir Res Hum Res Ethics 7:1-14. 2012
  4. pmc The need for medical education reform: genomics and the changing nature of health information
    Elizabeth A Nelson
    Undergraduate Medical Education, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030, USA
    Genome Med 2:18. 2010
  5. pmc Two cheers for GINA?
    Amy L McGuire
    Center for Medical Ethics and Health Policy, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA
    Genome Med 1:6. 2009
  6. pmc The futility of genomic counseling: essential role of electronic health records
    John Belmont
    Baylor College of Medicine, Department of Molecular and Human Genetics, Houston, Texas 77030, USA
    Genome Med 1:48. 2009
  7. pmc Social networkers' attitudes toward direct-to-consumer personal genome testing
    Amy L McGuire
    Center for Medial Ethics and Health Policy, Baylor College of Medicine, Houston, Texas 77030, USA
    Am J Bioeth 9:3-10. 2009
  8. ncbi request reprint Genetics. No longer de-identified
    Amy L McGuire
    Center for Medical Ethics and Health Policy, Baylor College of Medicine, Baylor College of Medicine, One Baylor Plaza, Suite 310D, Houston, TX 77030, USA
    Science 312:370-1. 2006
  9. pmc Informed consent in genomics and genetic research
    Amy L McGuire
    Center for Medical Ethics and Health Policy, Baylor College of Medicine, Houston, TX 77030, USA
    Annu Rev Genomics Hum Genet 11:361-81. 2010
  10. pmc Health system implications of direct-to-consumer personal genome testing
    Amy L McGuire
    Center for Medical Ethics and Health Policy, Baylor College of Medicine, Houston, TX 77030, USA
    Public Health Genomics 14:53-8. 2011

Detail Information

Publications30

  1. doi request reprint Confidentiality, privacy, and security of genetic and genomic test information in electronic health records: points to consider
    Amy L McGuire
    From the 1Center for Medical Ethics and Health Policy, Baylor College of Medicine, Houston, TX 77030, USA
    Genet Med 10:495-9. 2008
    ..These discussions can help guide policy that will facilitate the biological and clinical resource development to support the introduction of this information into health care...
  2. pmc "Snake-oil," "quack medicine," and "industrially cultured organisms:" biovalue and the commercialization of human microbiome research
    Melody J Slashinski
    Center for Medical Ethics and Health Policy, Baylor College of Medicine, Houston, TX 77030, USA
    BMC Med Ethics 13:28. 2012
    ....
  3. pmc Perspectives on human microbiome research ethics
    Amy L McGuire
    Baylor College of Medicine, Houston, TX, USA
    J Empir Res Hum Res Ethics 7:1-14. 2012
    ..Our findings demonstrate that investigators and recruits were similarly sensitive to these issues yet generally comfortable with study design in light of current knowledge about the microbiome...
  4. pmc The need for medical education reform: genomics and the changing nature of health information
    Elizabeth A Nelson
    Undergraduate Medical Education, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030, USA
    Genome Med 2:18. 2010
    ..Educational reform is needed across the continuum of medical education, from the student to the faculty training them, and requires a shift in focus from factual knowledge to data management and interpretation...
  5. pmc Two cheers for GINA?
    Amy L McGuire
    Center for Medical Ethics and Health Policy, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA
    Genome Med 1:6. 2009
    ..In the mean time, education about GINA and its limitations can help individuals make more informed decisions about genetic testing and participation in genetic research...
  6. pmc The futility of genomic counseling: essential role of electronic health records
    John Belmont
    Baylor College of Medicine, Department of Molecular and Human Genetics, Houston, Texas 77030, USA
    Genome Med 1:48. 2009
    ..Enter the electronic health record. We propose that without the integration of a dynamic uniform electronic health record, counseling patients on the basis of genome-wide data will be futile...
  7. pmc Social networkers' attitudes toward direct-to-consumer personal genome testing
    Amy L McGuire
    Center for Medial Ethics and Health Policy, Baylor College of Medicine, Houston, Texas 77030, USA
    Am J Bioeth 9:3-10. 2009
    ..This study explores social networkers' interest in and attitudes toward personal genome testing (PGT), focusing on expectations related to the clinical integration of PGT results...
  8. ncbi request reprint Genetics. No longer de-identified
    Amy L McGuire
    Center for Medical Ethics and Health Policy, Baylor College of Medicine, Baylor College of Medicine, One Baylor Plaza, Suite 310D, Houston, TX 77030, USA
    Science 312:370-1. 2006
  9. pmc Informed consent in genomics and genetic research
    Amy L McGuire
    Center for Medical Ethics and Health Policy, Baylor College of Medicine, Houston, TX 77030, USA
    Annu Rev Genomics Hum Genet 11:361-81. 2010
    ..All of these models attempt to balance the obligation to respect and protect research participants with the larger social interest in advancing beneficial research as quickly as possible...
  10. pmc Health system implications of direct-to-consumer personal genome testing
    Amy L McGuire
    Center for Medical Ethics and Health Policy, Baylor College of Medicine, Houston, TX 77030, USA
    Public Health Genomics 14:53-8. 2011
    ..In this article, we consider the health system implications of direct-to-consumer personal genome testing, focusing on issues of accountability, both corporate and professional...
  11. pmc Personal genome research : what should the participant be told?
    Amy L McGuire
    Center for Medical Ethics and Health Policy, Baylor College of Medicine, One Baylor Plaza, BCM420 Houston, Texas 77030, USA
    Trends Genet 26:199-201. 2010
    ..L.) experience as a geneticist who recently had his own genome sequenced...
  12. pmc Ethical and practical challenges of sharing data from genome-wide association studies: the eMERGE Consortium experience
    Amy L McGuire
    Center for Medical Ethics and Health Policy, Baylor College of Medicine, Houston, TX 77030, USA
    Genome Res 21:1001-7. 2011
    ..e., research participants, investigators, and research institutions), provide recommendations for researchers and institutions, and call for clearer guidance from the NIH regarding ethical implementation of its data-sharing policy...
  13. pmc Exploring the ELSI universe: critical issues in the evolution of human genomic research
    Jill M Oliver
    Center for Medical Ethics and Health Policy, Baylor College of Medicine, Houston, TX 77030, USA
    Genome Med 3:38. 2011
    ..A report on the National Human Genome Research Institute's Ethical, Legal, and Social Implications Research Program 2011 Congress, 'Exploring the ELSI Universe', Chapel Hill, North Carolina, USA, 12-14 April 2011...
  14. pmc DNA data sharing: research participants' perspectives
    Amy L McGuire
    Center for Medical Ethics and Health Policy, Baylor College of Medicine, Houston, Texas 77030, USA
    Genet Med 10:46-53. 2008
    ..The purpose of this study was to describe research participants' attitudes and judgments about data release and their preferences for varying levels of control over decision-making...
  15. pmc To share or not to share: a randomized trial of consent for data sharing in genome research
    Amy L McGuire
    Center for Medical Ethics and Health Policy, Baylor College of Medicine, Houston, TX 77030, USA
    Genet Med 13:948-55. 2011
    ..Our purpose was to assess the effect on research enrollment and data sharing decisions of three different consent types (traditional, binary, or tiered) with varying levels of control and choices regarding data sharing...
  16. pmc Medicine. The future of personal genomics
    Amy L McGuire
    Center for Medical Ethics and Health Policy, Baylor College of Medicine, Houston, TX 77030, USA
    Science 317:1687. 2007
  17. ncbi request reprint Missed expectations? Physicians' views of patients' participation in medical decision-making
    Amy L McGuire
    Center for Medical Ethics and Health Policy, Baylor College of Medicine, Houston, Texas 77098, USA
    Med Care 43:466-70. 2005
    ..Our objective was to identify and characterize physicians' attitudes toward patient participation in decision-making and to gain insight into how they consequently think about and structure the decision-making process...
  18. pmc Beneficent persuasion: techniques and ethical guidelines to improve patients' decisions
    J S Swindell
    Center for Medical Ethics and Health Policy, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030 4311, USA
    Ann Fam Med 8:260-4. 2010
    ..It is time for clinicians also to make use of behavioral psychology in their interactions with patients...
  19. doi request reprint Shaping patients' decisions
    J S Swindell
    Center for Medical Ethics and Health Policy, Baylor College of Medicine, Houston, TX, USA
    Chest 139:424-9. 2011
    ..In this article, we consider three such misconceptions with the goal of helping physicians to optimally promote their patients' interests...
  20. doi request reprint Beyond breaking bad news: the roles of hope and hopefulness
    Simon N Whitney
    Department of Family and Community Medicine, Baylor College of Medicine, Houston, Texas 77098 3926, USA
    Cancer 113:442-5. 2008
    ..Hope is important to patients, yet physicians are sometimes unsure how to promote hope in the face of life-threatening illness...
  21. pmc Principal investigator views of the IRB system
    Simon N Whitney
    Department of Family, Community Medicine, Houston Center for Education, Research on Therapeutics, Baylor College of Medicine, Houston, TX 77098 3926, USA
    Int J Med Sci 5:68-72. 2008
    ..Significant concern was expressed about the cost, inefficiency, and irrationality of IRB review. The IRB system works well for some researchers, but our results indicate that other investigators feel the costs outweigh the benefits...
  22. ncbi request reprint Meeting the growing demands of genetic research
    Amy L McGuire
    Center for Medical Ethics and Health Policy, Baylor College of Medicine, USA
    J Law Med Ethics 34:809-12. 2006
  23. pmc Developing a tissue resource to characterize the genome of pancreatic cancer
    Georgios Voidonikolas
    Michael E DeBakey Department of Surgery, Baylor College of Medicine, 1709 Dryden, Suite 1500, Houston, TX 77030, USA
    World J Surg 33:723-31. 2009
    ..This article summarizes the basic principles that guide the creation of such a repository, including sample processing and preservation techniques, sample size and composition, and collection of clinical data elements...
  24. doi request reprint Beyond shared decision making: an expanded typology of medical decisions
    Simon N Whitney
    Department of Family and Community Medicine, Baylor College of Medicine, Houston Center for Education and Research on Therapeutics, Houston, TX 77098 3926, USA
    Med Decis Making 28:699-705. 2008
    ..Conflict resolution requires acknowledging the potential for conflict...
  25. ncbi request reprint A typology of shared decision making, informed consent, and simple consent
    Simon N Whitney
    Department of Family and Community Medicine, Baylor College of Medicine, Houston 77098, USA
    Ann Intern Med 140:54-9. 2004
    ..In the continuing effort to provide patients with appropriate decisional authority over their own medical choices, shared decision making, informed consent, and simple consent each has a distinct role to play...
  26. pmc Whole-genome sequencing in a patient with Charcot-Marie-Tooth neuropathy
    James R Lupski
    Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA
    N Engl J Med 362:1181-91. 2010
    ..We therefore aimed to assess the usefulness of human whole-genome sequencing for genetic diagnosis in a patient with Charcot-Marie-Tooth disease...
  27. pmc Research ethics and the challenge of whole-genome sequencing
    Amy L McGuire
    Amy L McGuire is at the Center for Medical Ethics and Health Policy, Baylor College of Medicine, Houston, Texas 77030, USA
    Nat Rev Genet 9:152-6. 2008
    ..Although the issues are not new, we discuss their implications for personal genomics and provide recommendations for appropriate management in the context of research involving individual whole-genome sequencing...
  28. pmc Research ethics recommendations for whole-genome research: consensus statement
    Timothy Caulfield
    Health Law Institute, University of Alberta, Edmonton, Alberta, Canada
    PLoS Biol 6:e73. 2008
  29. ncbi request reprint Respect as an organizing normative category for research ethics
    Amy L McGuire
    Baylor College of Medicine
    Am J Bioeth 5:W1-2. 2005
  30. ncbi request reprint Consent: informed, simple, implied and presumed
    Laurence B McCullough
    Baylor College of Medicine
    Am J Bioeth 7:49-50; discussion W3-4. 2007

Research Grants4

  1. Ethical Legal and Social Dimensions of Human Microbiome Research
    AMY LYNN MCGUIRE; Fiscal Year: 2010
    ..We will also host a workshop with members of our research team, study participants, and outside experts to discuss the issues that were identified in the interviews and develop recommendations for managing them. ..
  2. The ethics of consent for the public release of potentially identifiable DNA data
    Amy McGuire; Fiscal Year: 2009
    ..Moreover, it will increase our understanding of participants' judgments and attitudes toward data sharing, which will improve the overall conduct of biomedical research, build public trust, and foster research participation. ..
  3. Ethical Legal and Social Dimensions of Human Microbiome Research
    Amy McGuire; Fiscal Year: 2009
    ..We will also host a workshop with members of our research team, study participants, and outside experts to discuss the issues that were identified in the interviews and develop recommendations for managing them. ..