Research Topics
| H M MalatySummaryAffiliation: Baylor College of Medicine Country: USA Publications
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Detail Information
Publications
Age at acquisition of Helicobacter pylori infection: a follow-up study from infancy to adulthoodHoda M Malaty
Department of Medicine, Veterans Affairs Medical Center and Baylor College of Medicine, Houston, TX 77030, USA
Lancet 359:931-5. 2002..Helicobacter pylori infection is common worldwide, but the time of acquisition is unclear. We investigated this issue in a cohort of children selected retrospectively from a population followed up for 21 years...
Natural history of Helicobacter pylori infection in childhood: 12-year follow-up cohort study in a biracial communityH M Malaty
Department of Laboratory Medicine, Veterans Affairs Medical Center and Baylor College of Medicine, Houston, Texas 77030, USA
Clin Infect Dis 28:279-82. 1999..H. pylori infection in childhood is affected by both acquisition and loss of infection in different ethnic groups. This observation is critical for understanding the epidemiology and transmission of H. pylori infection...
Multidimensional measure for gastroesophageal reflux disease (MM-GERD) symptoms in children: a population-based studyHoda M Malaty
Department of Medicine, University of Texas, Health Science Center, Houston, TX, USA
Acta Paediatr 97:1292-7. 2008..Evaluation of children with GERD symptoms continues to challenge physicians due to the lack of a validated measure for GERD symptoms...
Recurrent abdominal pain in school children: effect of obesity and dietHoda M Malaty
Department of Medicine, Children s Nutrition Research Center, Baylor College of Medicine, Houston, Texas 77030, USA
Acta Paediatr 96:572-6. 2007..To study the epidemiology and some of the risk factors of childhood recurrent abdominal pain (RAP) in school age children...
A prospective study for the association of Helicobacter pylori infection to a multidimensional measure for recurrent abdominal pain in childrenHoda M Malaty
Department of Medicine, Baylor College of Medicine, Houston, Texas 77030, USA
Helicobacter 11:250-7. 2006..There is a controversial association between Helicobacter pylori infection and recurrent abdominal pain (RAP) in childhood and inconsistent information on specific symptomatology of the infection...
Development of a multidimensional measure for recurrent abdominal pain in children: population-based studies in three settingsHoda M Malaty
Department of Medicine, Baylor College of Medicine, Houston, Texas, USA
Pediatrics 115:e210-5. 2005....
Epidemiology of Helicobacter pylori infectionHoda M Malaty
Department of Medicine at Baylor College of Medicine, Houston, TX, USA
Helicobacter 8:8-12. 2003..Moreover, this year attention was aimed at examining the associations between Helicobacter pylori with gastrointestinal and nongastrointestinal diseases...
Seroepidemiology of Helicobacter pylori and hepatitis A virus and the mode of transmission of infection: a 9-year cohort study in rural JapanHoda M Malaty
Department of Medicine, Veterans Affair Medical Center and Baylor College of Medicine, Houston, Texas 77030, USA
Clin Infect Dis 37:1067-72. 2003..The discordance between the presence of the infections among younger persons is evidence against a common source and/or vehicle for transmission...
Helicobacter pylori infection in asymptomatic children: impact of epidemiologic factors on accuracy of diagnostic testsHoda M Malaty
Department of Medicine, Veterans Affairs Medical Center and Baylor College of Medicine, Houston, Texas 77030, USA
J Pediatr Gastroenterol Nutr 35:59-63. 2002..Childhood is a time of high risk for acquiring H. pylori infection. Accurate information on the epidemiology of the infection requires accurate diagnostic tests...
Rising incidence of inflammatory bowel disease among children: a 12-year studyHoda M Malaty
Department of Medicine, Baylor College of Medicine, Houston, TX, USA
J Pediatr Gastroenterol Nutr 50:27-31. 2010..Data suggest an increase in the incidence of pediatric inflammatory bowel disease (IBD). We examined the trend of the incidence of IBD in children...
Are genetic influences on peptic ulcer dependent or independent of genetic influences for Helicobacter pylori infection?H M Malaty
Department of Medicine, Veterans Affairs Medical Center and Baylor College of Medicine, Houston, Texas 77030, USA
Arch Intern Med 160:105-9. 2000..Genetic factors play a role or roles in the etiology of peptic ulcer disease and the acquisition of Helicobacter pylori infection...
Evidence from a nine-year birth cohort study in Japan of transmission pathways of Helicobacter pylori infectionH M Malaty
Department of Medicine, Veterans Affairs Medical Center and Baylor College of Medicine, Houston, Texas, USA
J Clin Microbiol 38:1971-3. 2000..These data strongly support the cluster phenomenon of H. pylori infection among families, the key role of the infected mothers in the transmission within families, and the importance of adult-child transmission and not vice versa...
Helicobacter pylori infection and eradication in paediatric patientsH M Malaty
Department of Medicine, Veterans Affairs Medical Center and Baylor College of Medicine, Houston, Texas 77030, USA
Paediatr Drugs 2:357-65. 2000..pylori infection and recurrent abdominal pain (RAP) in children, in part because of the unclear definition of RAP in the literature. Therefore, there is still considerable debate regarding the treatment of infected children with RAP...
Helicobacter pylori infection in preschool and school-aged minority children: effect of socioeconomic indicators and breast-feeding practicesH M Malaty
Department of Medicine, Veterans Affairs Medical Center and Baylor College of Medicine, Houston, TX 77030, USA
Clin Infect Dis 32:1387-92. 2001..pylori infection. Understanding the epidemiology of H. pylori infection in childhood requires better understanding of the interactions between environment, ethnic group, and socioeconomic conditions...
Helicobacter pylori infection in children of TexasA R Opekun
Department of Pediatrics, Baylor College of Medicine, Texas Children s Hospital and Veterans Affairs Medical Center, Houston 77030 2399, USA
J Pediatr Gastroenterol Nutr 31:405-10. 2000..pylori infection in children of different ethnic groups in relation to socioeconomic class and investigates the prevalence of acute H. pylori infection among children who have had recent onset of abdominal pain...
Pattern of primary resistance of Helicobacter pylori to metronidazole or clarithromycin in the United StatesM S Osato
Gastroenterology Microbiology Laboratory, Department of Medicine, Veterans Affairs Medical Center, MS 111D, 2002 Holcombe Boulevard, Houston, TX 77030
Arch Intern Med 161:1217-20. 2001..The aim of this study was to aid clinicians in choosing a course of therapy for H pylori infection in the United States...
Conservation of Helicobacter pylori genotypes in different ethnic groups in Houston, TexasY Yamaoka
Department of Medicine, Veterans Affairs Medical Center, Houston, TX 77030, USA
J Infect Dis 181:2083-6. 2000..Conservation of an H. pylori genotype within ethnic groups over the course of generations will prove useful for epidemiological study of the coevolution of humans and H. pylori...
Alendronate gastric ulcersD Y Graham
Department of Medicine, Veterans Affairs Medical Center, Houston, TX 77030, USA
Aliment Pharmacol Ther 13:515-9. 1999..We have previously shown that the dose of alendronate used for Paget's disease (40 mg) causes gastric damage similar to NSAIDs. The usual dose for the treatment of postmenopausal osteoporosis is 10 mg per day...
Simplified 13C-urea breath test for detection of Helicobacter pylori infectionD Y Graham
Department of Medicine and Veterans Affairs Medical Center, Baylor College of Medicine, Houston, Texas 77030, USA
Am J Gastroenterol 96:1741-5. 2001..S. standard 13C-UBT offering less expensive ingredients, shorter test duration, and a simplified breath test collection method, without sacrificing accuracy...
Contemplating the future without Helicobacter pylori and the dire consequences hypothesisDavid Y Graham
Department of Medicine, Michael E DeBakey VAMC and Baylor College of Medicine, Houston, Texas 77030, USA
Helicobacter 12:64-8. 2007..It is time to join together to eradicate it and to let H. pylori join smallpox and polio on the hit list of undesirables...
Thoughts about populations with unexpected low prevalences of Helicobacter pylori infectionDavid Y Graham
Department of Medicine, Michael E DeBakey VAMC, Texas 77030, USA
Trans R Soc Trop Med Hyg 101:849-51. 2007..Why some populations apparently lost H. pylori infection remains an open question. However, the tools needed to resolve the dilemma are readily available and we hope investigators will soon rise to the challenge...
Epidemiology of Helicobacter pylori infectionHoda M Malaty
Department of Medicine, Veterans Affairs Medical Center 111D and Baylor College of Medicine, 2002 Holcombe Blvd, Houston, TX 77030, USA
Best Pract Res Clin Gastroenterol 21:205-14. 2007..Gastric cancer does not usually manifest until old age. The infection has a high morbidity rate, but a low mortality rate and is curable with antibiotic therapy...
Commentary: What remains to be done regarding transmission of Helicobacter pyloriDavid Y Graham
Department of Medicine, VA Medical Center and Baylor College of Medicine, Houston, Texas 77030, USA
Int J Epidemiol 31:646-7. 2002
Helicobacter pylori infection in Kazakhstan: effect of water source and household hygieneZhannat Z Nurgalieva
Department of Faculty Therapy, Almaty State Medical University, Almaty, Kazakhstan
Am J Trop Med Hyg 67:201-6. 2002..Reducing the rate of H. pylori transmission will require improvements in overall sanitation including clean water, waste disposal, as well as in household hygienic practices...
Risk Factors Associated with Helicobacter pylori Infection among Children in a Defined Geographic AreaMaria P Dore
Institute of Clinica Medica, University of Sassari, Sassari, Italy and Department of Medicine, Gastrointestinal Section, VA Medical Center and Baylor College of Medicine, Houston, TX, USA
Clin Infect Dis 35:240-5. 2002..5; 95% CI, 1.1-2.0; P<.05). The epidemiology of H. pylori infection is complex; even within the same geographic area, different factors influence acquisition of H. pylori infection...
Alendronate and naproxen are synergistic for development of gastric ulcersD Y Graham
Veterans Affairs Medical Center (111D, 2002 Holcombe Blvd, Houston, TX 77030, USA
Arch Intern Med 161:107-10. 2001..CONCLUSIONS: Both alendronate and naproxen can cause gastric ulcers. The combination appears synergistic. Alendronate should be used with caution in those who simultaneously require nonsteroidal anti-inflammatory drugs...
Effect of antisecretory therapy on atypical symptoms in gastroesophageal reflux diseaseMaria Pina Dore
Istituto di Clinica Medica, Universita di Sassari, Viale San Pietro 8, Sassari, Italy
Dig Dis Sci 52:463-8. 2007..We conclude that atypical symptoms are frequent in patients with GERD. A trial of PPI therapy should be considered prior to referring these patients to specialists...
Dramatic changes in the prevalence of Helicobacter pylori infection during childhood: a 10-year follow-up study in RussiaMikhail A Tkachenko
Department of Pediatrics 1, Russia
J Pediatr Gastroenterol Nutr 45:428-32. 2007..This phenomenon has been related to differences in socioeconomic status, sanitation, and household hygiene. Russia is in the process of transforming from an underdeveloped to a developed country...
Diet, lifestyle and gender in gastro-esophageal reflux diseaseMaria Pina Dore
Istituto di Clinica Medica, Universita di Sassari, Sassari, Italy
Dig Dis Sci 53:2027-32. 2008..Studies indicate that gastro-esophageal reflux disease (GERD) is associated with obesity, smoking, esophagitis, diet, and lifestyle...
