Research Topics
| VICTORIA J LUNDBLADSummaryAffiliation: Baylor College of Medicine Country: USA Publications
Research Grants
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Detail Information
Publications
Molecular biology. Telomeres keep on rappin'V Lundblad
Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA
Science 288:2141-2. 2000..The homology between hRap1 and its counterpart in yeast suggests how the complex molecular machinery needed to maintain chromosome ends may have evolved...
DNA ends: maintenance of chromosome termini versus repair of double strand breaksV Lundblad
Department of Molecular and Human Genetics, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA
Mutat Res 451:227-40. 2000..The significance of these common components is discussed, as well as the types of DNA repair events that can compensate for a defective telomere...
Genome instability: McClintock revisitedV Lundblad
Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA
Curr Biol 11:R957-60. 2001..Furthermore, examination of the consequences of telomerase loss in mice suggests that only a few critically short telomeres may be sufficient to promote genomic instability...
Telomere maintenance without telomeraseVictoria Lundblad
Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, TX 77030, USA
Oncogene 21:522-31. 2002..These observations provide new insights into the mechanism(s) by which recombination can restore telomere function in yeast, and suggest future experiments for the investigation of potentially similar pathways in human cells...
Telomere replication: an Est festVicki Lundblad
Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA
Curr Biol 13:R439-41. 2003..Thus, positive regulation of telomerase by Est1 appears to be a widely utilized mechanism for maintaining telomere length homeostasis...
Research Grants
- DUAL ROLE FOR CDC13 IN YEAST TELOMERE FUNCTIONVictoria Lundblad; Fiscal Year: 2004..Characterization of the dual nature of this essential yeast telomere protein may serve as a paradigm for similar events at mammalian telomeres. ..
- TELOMERE REPLICATION AND SENESCENCE IN YEASTVictoria Lundblad; Fiscal Year: 2007..In this application, we propose a set of experiments intended to form an integrated picture of how these positive and negative regulators of telomerase control telomere replication. ..
