Research Topics
Genomes and GenesSpecies | W LiSummaryAffiliation: Baylor College of Medicine Country: USA Publications
| Collaborators
|
Detail Information
Publications
Characteristics of Epstein-Barr virus-associated gastric cancer: a study of 235 cases at a comprehensive cancer center in U.S.ACamtu D Truong
The University of Texas MD Anderson Cancer Center, Houston, TX, USA
J Exp Clin Cancer Res 28:14. 2009..The aims of this study were to evaluate EBV-associated gastric cancer, to assess the distribution of EBV infected cells including all positive lymph nodes, and to define the characteristics of EBV-associated gastric cancer...
Activation of Akt-mTOR-p70S6K pathway in angiogenesis in hepatocellular carcinomaWei Li
Department of Pathology and Laboratory Medicine, University of Texas Health Science Center at Houston, TX 77030, USA
Oncol Rep 20:713-9. 2008..Molecular strategies aimed at inhibiting this signal pathway may be of therapeutic use for the treatment of HCC...- Significance of overexpression of alpha methylacyl-coenzyme A racemase in hepatocellular carcinomaWei Li
Department of Pathology, University of Texas Health Science Center at Houston, Houston, TX 77030, USA
J Exp Clin Cancer Res 27:2. 2008..This study aims to evaluate immunohistochemical expression of the AMACR in neoplastic and nonneoplastic liver lesions, and assess its value in the diagnosis of hepatocellular carcinoma (HCC)... - Immunohistochemical expression of stromal cell-derived factor-1 (SDF-1) and CXCR4 ligand receptor system in hepatocellular carcinomaW Li
Department of Pathology and Laboratory Medicine, University of Texas Health Science Center at Houston, 77030, USA
J Exp Clin Cancer Res 26:527-33. 2007..Our data suggest that molecular strategies aimed at inhibiting the CXCR4/SDF-1 pathway might be of therapeutic use for the treatment of HCC... - Constitutive activation of nuclear factor-kappa B (NF-kB) signaling pathway in fibrolamellar hepatocellular carcinomaWei Li
Department of Pathology and Laboratory Medicine, University of Texas Health Science Center at Houston, Houston, TX 77030, USA
Int J Clin Exp Pathol 3:238-43. 2010..Constitutive NF-kB activation was observed in FLHCC. The findings suggest that NF-kB activation is involved in the tumorigenesis of FLHCC and may represent novel targets for therapeutic intervention to FLHCC... - Idiopathic nodular glomerulosclerosis: a clinicopathologic study of 15 casesWei Li
Department of Pathology and Laboratory Medicine, University of Texas Health Science Center at Houston, Houston, TX 77030, USA
Hum Pathol 39:1771-6. 2008.... - Coupling from AII amacrine cells to ON cone bipolar cells is bidirectionalE B Trexler
Department of Ophthalmology and Visual Science, University of Texas Medical School, Houston, Texas 77030, USA
J Comp Neurol 437:408-22. 2001..The previous failure to detect the passage of neuronal tracer from injected bipolar cells to AII amacrine cells may reflect electrode damage or perhaps the asymmetrical voltage sensitivity of a heterotypic gap junction... - Computational methods for gene expression-based tumor classificationM Xiong
University of Texas Houston Health Science Center, Houston, TX, USA
Biotechniques 29:1264-8, 1270. 2000..0%. The combined approach using principal components and discriminant analysis provided superior sensitivity and specificity compared to an approach using simple differences in the expression levels of individual genes... - Rod pathways in the mammalian retina use connexin 36S L Mills
Department of Ophthalmology and Visual Science, University of Texas at Houston Health Science Center, Houston, Texas 77030, USA
J Comp Neurol 436:336-50. 2001..Conversely, Cx36 labeling in other regions of the retina is not associated with AII amacrine cells, indicating some other cell types use Cx36... - A novel Pax-6 binding site in rodent B1 repetitive elements: coevolution between developmental regulation and repeated elements?Y Zhou
Department of Biochemistry, The University of Texas M D Anderson Cancer Center, Houston, TX, USA
Gene 245:319-28. 2000.... - Mediation of N-(4-hydoxyphenyl)retinamide-induced apoptosis in human cancer cells by different mechanismsS Y Sun
Department of Thoracic Head and Neck Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston 77030, USA
Cancer Res 59:2493-8. 1999.... - Feature (gene) selection in gene expression-based tumor classificationM Xiong
Human Genetics Center, University of Texas Houston Health Science Center, Houston, Texas 77225, USA
Mol Genet Metab 73:239-47. 2001..In this report we also show that stepwise Fisher's linear discriminant function is a practicable method for gene expression-based tumor classification... - Population based linkage disequilibrium mapping of QTL: an application to simulated data in an isolated populationJ Zhao
Human Genetics Center, University of Texas-Houston, Houston, Texas, USA
Genet Epidemiol 21:S655-9. 2001..The proposed method is applied to search for polymorphism sites within the candidate genes 2 and 6, which influence quantitative traits Q1 and Q2 or Q5, in a simulated data set in an isolated population... - Multiple neuronal connexins in the mammalian retinaStephen C Massey
Department of Ophthalmology and Visual Science, University of Texas Medical School at Houston, Houston, TX 77030, USA
Cell Commun Adhes 10:425-30. 2003..Horizontal cells appear to be extensively coupled by either Cx50 or Cx57. These results indicate that multiple neuronal connexins are expressed in the mammalian retina and that different cell types express different connexins... - Separate blue and green cone networks in the mammalian retinaWei Li
Department of Ophthalmology, Northwestern University Medical School, 303 East Chicago Avenue, Tarry 5 715, Chicago, Illinois 60611, USA
Nat Neurosci 7:751-6. 2004..Together with a lack of tracer coupling and the selective localization of connexin proteins, our results show that signals in blue and green cones are processed separately in the photoreceptor layer... - Coupling between A-type horizontal cells is mediated by connexin 50 gap junctions in the rabbit retinaWei Li
Department of Ophthalmology and Visual Science, University of Texas Medical School at Houston, Houston, Texas 77030, USA
J Neurosci 26:11624-36. 2006..In summary, these results suggest that gap junctions in the A-type horizontal cell matrix are composed from Cx50. Multiple neuronal connexins are expressed in the mammalian retina and different cell types express specific connexins... - Characterization of somatostatin receptor expression in human pancreatic cancer using real-time RT-PCRMin Li
Elkins Pancreas Center and Molecular Surgeon Research Center, Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, Texas 77030, USA
J Surg Res 119:130-7. 2004..Down-regulation of SSTR transcription or SSTR mRNA instability may result in loss of a tumor suppressive effect of SSTRs in human pancreatic cancer... 
A "traffic control" role for TGFbeta3: orchestrating dermal and epidermal cell motility during wound healingBalaji Bandyopadhyay
Department of Dermatology and Norris Comprehensive Cancer Center, University of Southern California Keck School of Medicine, Los Angeles, CA 90033, USA
J Cell Biol 172:1093-105. 2006..Therefore, the naturally occurring plasma-->serum-->plasma transition during wound healing orchestrates the orderly migration of dermal and epidermal cells...- AMPA receptors mediate acetylcholine release from starburst amacrine cells in the rabbit retinaSally I Firth
Department of Neurobiology and Anatomy, University of Texas Medical School, Houston, Texas, 77225, USA
J Comp Neurol 466:80-90. 2003..The AMPA receptors are expected to desensitize rapidly, enhancing the sensitivity of starburst amacrine cells to moving or other rapidly changing stimuli... - Coupling pattern of S1 and S2 amacrine cells in the rabbit retinaWei Li
Department of Ophthalmology and Visual Science, University of Texas-Houston Medical School, USA
Vis Neurosci 19:119-31. 2002..By comparison, the smaller, weakly coupled S2 amacrine cells may provide a local component... - Morphoproteomic profile of mTOR, Ras/Raf kinase/ERK, and NF-kappaB pathways in human gastric adenocarcinomaWei Feng
Department of Pathology, MD Anderson Cancer Center, Houston, TX 77030, USA
Ann Clin Lab Sci 38:195-209. 2008.... - Signal transduction in human pancreatic cancer: roles of transforming growth factor beta, somatostatin receptors, and other signal intermediatesMin Li
Molecular Surgeon Research Center, Michael E DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX 77021, USA
Arch Immunol Ther Exp (Warsz) 53:381-7. 2005.... - Transcriptional regulatory networks downstream of TAL1/SCL in T-cell acute lymphoblastic leukemiaTeresa Palomero
Institute for Cancer Genetics, Columbia University, 1150 St Nicholas Ave, New York, NY 10032, USA
Blood 108:986-92. 2006..Our results indicate that TAL1 may act as a bifunctional transcriptional regulator (activator and repressor) at the top of a complex regulatory network that disrupts normal T-cell homeostasis and contributes to leukemogenesis... - Role of AKT in cyclic strain-induced endothelial cell proliferation and survivalKengo Nishimura
Department of Surgery, Section of Vascular Surgery, Yale University School of Medicine, 333 Cedar St, FMB 137, New Haven, CT 06520-8062, USA
Am J Physiol Cell Physiol 290:C812-21. 2006..We conclude that AKT is important in enhancing the survival of ECs exposed to CS but is not involved in EC proliferation... - Structural and functional insights into the regulation of Arabidopsis AGC VIIIa kinasesHicham Zegzouti
Department of Molecular, Cell, and Developmental Biology, David Geffen School of Medicine, University of California, Los Angeles 90095, USA
J Biol Chem 281:35520-30. 2006..The initial characterization of the AGCVIIIa kinases presented here provides a framework for elucidating the physiological roles of these kinases in planta... - Mechanism for fetal hemoglobin induction by histone deacetylase inhibitors involves gamma-globin activation by CREB1 and ATF-2Jose Sangerman
Department of Pediatrics, Yale University, New Haven, CT, USA
Blood 108:3590-9. 2006..The data presented herein demonstrate that gamma-gene induction by butyrate and trichostatin A involves ATF-2 and CREB1 activation via p38 MAPK signaling... - Agonistic monoclonal antibodies potentiate tumorigenic and invasive activities of splicing variant of the RON receptor tyrosine kinaseHang-ping Yao
Laboratory of Cheung Kong Scholars Program for Tumor Biology, Institute of Infectious Diseases at First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China
Cancer Biol Ther 5:1179-86. 2006..These mAbs will be useful in studying mechanisms underlying RON activation which lead to increased tumorigenic activities... - p300/Cyclic AMP-responsive element binding-binding protein mediates transcriptional coactivation by the CD28 T cell costimulatory receptorSarada L Nandiwada
Rheumatic and Autoimmune Diseases Division, and Center for Immunology, University of Minnesota Medical School, 312 Church Street SE, Minneapolis, MN 55455, USA
J Immunol 177:401-13. 2006..These data suggest a global mechanism whereby CD28 signaling influences the rate and intensity of new gene expression during Ag recognition via direct control over the coactivator function of p300/CBP... - Effects of heat shock protein gp96 on human dendritic cell maturation and CTL expansionYuxia Zhang
Molecular Virology Research Center, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100080, PR China
Biochem Biophys Res Commun 344:581-7. 2006..In HLA-A2.1/Kb transgenic mice, gp96 and the recombinant fragments were found to augment CTL response specific for the HBcAg(18-27) FLPSDFFPSV peptide of hepatitis B virus... - Bipolar cell pathways for color and luminance vision in a dichromatic mammalian retinaWei Li
Department of Ophthalmology, Northwestern University Medical School, 303 East Chicago Avenue, Tarry 5 715, Chicago, Illinois 60611, USA
Nat Neurosci 9:669-75. 2006..Bipolar cells that carry S- or M-cone signals can have a role in color discrimination and may contact color-opponent ganglion cells. Bipolar cells that sum signals from S- and M-cones may signal to ganglion cells that encode luminance... - Pax6 overexpression suppresses cell proliferation and retards the cell cycle in corneal epithelial cellsJie Ouyang
Bascom Palmer Eye Institute, Miller School of Medicine, University of Miami, FL 33136, USA, and Department of Ophthalmology, Veterans General Hospital, Taichung, Taiwan
Invest Ophthalmol Vis Sci 47:2397-407. 2006..CONCLUSIONS: Inhibition of cell proliferation in Pax6-overexpressing corneal epithelial cell lines and primary cell culture is consistent with the notion that Pax6 plays a role in controlling corneal epithelial cell dynamics in vivo... - [Liver transplantation for the treatment of hepatocellular carcinoma]Xin-Guo Chen
Department of Liver Transplantation, General Hospital of Armed Police Forces, Beijing 100039, China
Zhonghua Zhong Liu Za Zhi 28:628-31. 2006..2%, 71.5% and 41.7%, respectively (P < 0.01). CONCLUSION: Liver transplantation may be suitable for stage I or II hepatocellular cancer patients and improve their prognosis, while it is not suitable for stage IV HCC patients... - Cell competition and its possible relation to cancerNicholas E Baker
Department of Molecular Genetics, Albet Einstein College of Medicine, Bronx, New York 10461, USA
Cancer Res 68:5505-7. 2008..Here, we discuss the possible relevance of cell competition to cancer... - Increased survivin expression confers chemoresistance to tumor-associated endothelial cellsJenilyn J Virrey
Departments of Pathology, University of Southern California, Keck School of Medicine, 2011 Zonal Ave, HMR 315A, Los Angeles, CA 90033, USA
Am J Pathol 173:575-85. 2008..Our studies demonstrate that targeting survivin may be an effective approach to chemosensitization and anti-vascular therapy for brain tumors... - Comparison of cerebral glucose metabolism between multiple system atrophy Parkinsonian type and Parkinson's diseaseTao Feng
Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
Neurol Res 30:377-82. 2008..To investigate the difference in the regional cerebral glucose metabolism between multiple system atrophy Parkinsonian type (MSA-P) and Parkinson's disease (PD)... - A rare case of ossification of a celiac cystYong He
Thoracic Surgery Center, Daping Hospital, Third Military Medical University, Chongqing, China
Am J Surg 196:e25-6. 2008..There has been little report on calcification of cysts inside the abdomen. Here we report a rare case of ossification of celiac cyst. If we understand the images of calcified and ossified cysts, a correct diagnosis can be made... - Transforming growth factor alpha (TGFalpha)-stimulated secretion of HSP90alpha: using the receptor LRP-1/CD91 to promote human skin cell migration against a TGFbeta-rich environment during wound healingChieh Fang Cheng
Department of Dermatology, University of Southern California Keck School of Medicine, 1441 Eastlake Ave, Room 6320, Los Angeles, CA 90033, USA
Mol Cell Biol 28:3344-58. 2008..This finding provides a long-sought answer to the question of how dermal cells migrate into the wound environment to build new connective tissues and blood vessels. Thus, secreted hsp90alpha is potentially a new agent for wound healing... - Cardiac restricted overexpression of kinase-dead mammalian target of rapamycin (mTOR) mutant impairs the mTOR-mediated signaling and cardiac functionWei Hua Shen
Herman B Wells Center for Pediatric Research, Division of Pediatric Cardiology and Neonatology, Department of Pediatrics, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
J Biol Chem 283:13842-9. 2008..Additional analysis of cardiac responses to fasting-refeeding or acute insulin administration indicated that alphaMHC-mTORkd mice had a largely impaired physiological response to nutrient energy supply and insulin stimulation... - Optimization of b value in diffusion-weighted MRI for the differential diagnosis of benign and malignant vertebral fracturesGuangyu Tang
Department of Radiology, Affiliated Tenth People s Hospital of Tongji University, Shanghai 200072, China
Skeletal Radiol 36:1035-41. 2007..The objective was to explore the optimal b value in diffusion-weighted imaging (DWI) of MRI for differential diagnosis of benign and malignant vertebral fractures... - Molecular cloning and characterization of a putative protein kinase gene from the thermophilic fungus Thermomyces lanuginosusDuo Chuan Li
Department of Environmental Biology, Shandong Agricultural University, Taian, Shandong, People s Republic of China
DNA Seq 18:423-33. 2007..The putative protein kinase contained three arginine/serine-rich (SR) regions and two transmembrane domains. These showed that it might be a novel putative serine-threonine protein kinase... - Regulation of carbon and nitrogen utilization by CbrAB and NtrBC two-component systems in Pseudomonas aeruginosaWei Li
Department of Biology, Georgia State University, 24 Peachtree Center Ave, Atlanta, GA 30303, USA
J Bacteriol 189:5413-20. 2007..aeruginosa. Possible molecular mechanisms of these two regulatory elements in the control of arginine and histidine operons used as the model systems are discussed... - Translational regulation of rat multidrug resistance-associated protein 2 expression is mediated by upstream open reading frames in the 5' untranslated regionYuanyuan Zhang
Graduate Center for Toxicology, University of Kentucky, Lexington, KY 40536 0305, USA
Mol Pharmacol 71:377-83. 2007..We conclude that among the uORFs in the Mrp2 5'UTR, the uORF starting at nucleotide -109 probably plays an important role in the regulation of Mrp2 protein expression... - Multiple signaling pathways are involved in endothelin-1-induced brain endothelial cell migrationJohanna Milan
Department of Cell Biology and Neuroscience, University of California, Riverside, 92521, USA
Am J Physiol Cell Physiol 291:C155-64. 2006..Because many signal transduction pathways investigated in this study are potential or current targets for anti-angiogenesis therapy, these results are of critical importance for designing physiological antiangiogenic protocols... - The role of microRNA genes in papillary thyroid carcinomaHuiling He
Human Cancer Genetics Program, Department of Pathology, Ohio State University, Columbus, OH 43210, USA
Proc Natl Acad Sci U S A 102:19075-80. 2005..We conclude that up-regulation of several miRs and regulation of KIT are involved in PTC pathogenesis, and that sequence changes in genes targeted by miRNAs can contribute to their regulation... - Simultaneous contribution of two rod pathways to AII amacrine and cone bipolar cell light responsesE Brady Trexler
Department of Ophthalmology and Neuroscience, University of Texas Medical School, Houston, Texas, USA
J Neurophysiol 93:1476-85. 2005..Thus for a large range of intensities, rod signals reach the inner retina by both rod bipolar-AII and rod-cone coupling pathways... - [Correlation of tumor microvessel density to metastasis and recurrence of rectal cancer]Ying Bo Chen
Department of Abdominal Surgery, Cancer Center, Sun Yat Sen University, Guangzhou, Guangdong, 510060, P R China
Ai Zheng 23:1203-6. 2004..However, the relationship between tumor MVD and the clinicopathological characteristics of rectal cancer are unclear. This study was to explore the correlation of tumor MVD to metastasis and recurrence of rectal cancer... - Direct synaptic connections between rods and OFF cone bipolar cells in the rabbit retinaWei Li
Department of Ophthalmology and Visual Science, University of Texas Medical School at Houston, Texas 77030, USA
J Comp Neurol 474:1-12. 2004..In summary, we report anatomical evidence for direct connections between rods and OFF cone bipolar cells in a nonrodent mammal. Our data suggest that this alternative rod pathway may be a common feature of the mammalian retina... - Experiment study of retinal ultrastructure after intravitreal FK506Shuangnong Li
Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, China
Yan Ke Xue Bao 20:34-8. 2004..CONCLUSION: It is safety with intravitreal FK506. There are no irritation and toxicity to the rabbits eyes with the intravitreal doses of 25 micrograms FK506 or less. The doses of 50 micrograms FK506 are proved to be toxic to the retina... - Giant mediastinal bronchial artery aneurysm mimicking benign esophageal tumor: a case report and review of 26 cases from literatureKuniyoshi Tanaka
Department of Surgery II, Fukui Medical University School of Medicine, Japan
J Vasc Surg 38:1125-9. 2003..Postoperative course was uneventful, and the patient was discharged on the seventh postoperative day... - Treatment of migraine with acupuncture at points pertaining to the liver and gallbladder channelsWei Li
Xiangya Hospital of Zhongnan University, Changsha 410008, Hunan Province
J Tradit Chin Med 23:205-6. 2003 - Fibronectin blocks p38 and jnk activation by cyclic strain in Caco-2 cellsJianhu Zhang
Department of Surgery, John D Dingell Veterans Administration Hospital Chief VAMC, Surgical Service 112, 4646 John R Street, Detroit, MI 48201 1932, USA
Biochem Biophys Res Commun 306:746-9. 2003..Since tissue and plasma fibronectin levels vary in acute or chronic inflammatory or infectious conditions, these results suggest that tissue or plasma fibronectin may modulate the intestinal epithelial response to repetitive deformation... - Regulation of the intestinal epithelial response to cyclic strain by extracellular matrix proteinsJianhu Zhang
Departments of Surgery, Wayne State University, USA
FASEB J 17:926-8. 2003..Tissue or plasma fibronectin may regulate the intestinal epithelial response to strain via integrins containing alpha5 or alpha(v)... - Evaluation of responses to chemoembolization in patients with unresectable hepatocellular carcinomaOsama M Ebied
Department of Radiology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
Cancer 97:1042-50. 2003..However, even patients classified by CT as hypervascular nonresponders and hypovascular responders have improved survival... - Connexin26 gene ( GJB2): prevalence of mutations in the Chinese populationYuhe Liu
Department of Otolaryngology Head and Neck Surgery, Peking University First Hospital, Beijing 100034, China
J Hum Genet 47:688-90. 2002..It appears from our limited data and reports from other East Asians that 235delC is the most prevalent GJB2 mutation in these populations. GJB2 mutations are consistent with ethnic predilections... - Confocal analysis of reciprocal feedback at rod bipolar terminals in the rabbit retinaJian Zhang
Department of Ophthalmology and Visual Science, University of Texas-Houston Medical School, Houston, Texas 77030, USA
J Neurosci 22:10871-82. 2002..In contrast, the larger, better-coupled S1 amacrine cells may provide a more distant network signal... - Up-regulated transcriptional repressors SnoN and Ski bind Smad proteins to antagonize transforming growth factor-beta signals during liver regenerationMarina Macias-Silva
Department of Genetics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
J Biol Chem 277:28483-90. 2002..Our data show that active TGF-beta/Smad signals are present during regeneration and suggest that SnoN/Ski induction might explain hepatocyte resistance to TGF-beta during the proliferative phase... - Epstein-Barr virus in hepatocellular carcinogenesisWei Li
Department of General Surgery, The First Affiliated Hospital of Shantou University Medical College, Shantou 515041, Guangdong Province, China
World J Gastroenterol 10:3409-13. 2004..The present study was to determine the prevalence of EBV in HCC patients, and whether EBV acted synergistically with hepatitis viruses in HCC carcinogenesis... - [EB virus encoded latent membrane protein 1 mediated expression of transcription factor Ets-1 in nasopharyngeal carcinoma cells]Liang Zeng
Department of Pathology, Cancer Research Institute, Xiangya School of Medicine, Central South University, Changsha 410078, China
Zhonghua Zhong Liu Za Zhi 26:454-7. 2004..CONCLUSION: LMP1 induces transcriptional activation and expression of Ets-1 which may contribute to the development of NPC... - [Palliative surgery combined with oxaliplatin-based chemotherapy in treatment of patients with advanced gastric cancer]Ying Bo Chen
Department of Abdominal Surgery, Cancer Center, Sun Yat Sen University, Guangzhou, Guangdong, 510060, P R China
Ai Zheng 23:1520-2. 2004.... - The heterogeneous murine corneal stromal cell populations in vitroEdgar M Espana
TissueTech, Inc. and Ocular Surface Center, Miami, Florida 33173, USA
Invest Ophthalmol Vis Sci 46:4528-35. 2005..This potential is disrupted by the addition of TGF-beta1 to the culture medium... - Stratification of alpha ganglion cells and ON/OFF directionally selective ganglion cells in the rabbit retinaJian Zhang
Department of Ophthalmology and Visual Science, University of Texas Medical School at Houston, Houston, TX 77030, USA
Vis Neurosci 22:535-49. 2005..We conclude that the precise level of stratification is correlated with the strength of cholinergic input. Alpha ganglion cells receive a weak cholinergic input and they are narrowly stratified just below the cholinergic bands... - [Antisense hypoxia inducible factor-1alpha and B7-1 combination gene therapy for mouse lymphoma]Xue Ying Sun
Hepatosplenic Surgery Center of Heilongjiang Province, The First Clinical College of Harbin Medical University, Harbin 150001, China
Zhonghua Zhong Liu Za Zhi 27:404-7. 2005..To investigate the synergistic effects of antisense HIF-1alpha gene therapy combined with B7-1-mediated immunotherapy on cancer treatment... - [Efficacy of gefitinib on Chinese patients with locally advanced or metastatic non-small cell lung cancer: a clinical trial]Zhong Zhen Guan
Skate Key Laboratory of Oncology in Southern China, Cancer Center, Sun Yat Sen University, Guangzhou, Guangdong, P R China
Ai Zheng 24:980-4. 2005..This study, a multicenter clinical trial, was designed to evaluate the efficacy of gefitinib on Chinese patients with locally advanced or metastatic NSCLC after failure of previous chemotherapy, and explore its safety... - Comparative analysis of the pig BAC sequence involved in the regulation of myostatin geneZhengquan Yu
State Key Laboratory for Agrobiotechnology, China Agricultural University, Beijing 100094, China
Sci China C Life Sci 48:168-80. 2005..Many putative transcription factors play an important role in the muscle development, and the complex interaction between myostatin and these factors may be required for proper muscle development... - [Isolation and identification of endothelial progenitor cells from peripheral blood]Li-ping Ma
Zhonghua Bing Li Xue Za Zhi 34:115-7. 2005 - Ribozymes against TGFbeta1 reverse character of activated hepatic stellate cells in vitro and inhibit liver fibrosis in ratsYu-hu Song
Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, Hubei Province, China
J Gene Med 7:965-76. 2005..It indicated that TGFbeta1 could be considered as a novel candidate for a therapeutic agent against hepatic fibrosis... - Expression of cyclooxygenase-2 and inducible nitric oxide synthase correlates with tumor angiogenesis in endometrial carcinomaWei Li
Department of Gynecology and Obstetrics, First People s Hospital Hangzhou, Hangzhou Zhejiang 310006, PR China
Med Oncol 22:63-70. 2005.... - Rosuvastatin attenuates monocyte-endothelial cell interactions and vascular free radical production in hypercholesterolemic miceWei Li
Division of Cardiovascular Medicine, Stanford University School of Medicine, CA 94305-5246, USA
J Pharmacol Exp Ther 313:557-62. 2005..Thus, treatment with rosuvastatin has acute anti-inflammatory actions that likely participate in its beneficial actions during atherogenesis... - Regulation of connexin43-protein binding in astrocytes in response to chemical ischemia/hypoxiaWei Li
Department of Neuroscience, Albert Einstein College of Medicine, Bronx, New York 10461, USA
J Biol Chem 280:7941-8. 2005..These results identify new binding partners for connexin43 and demonstrate that interactions between connexin43 and protein kinases and phosphatases are dynamically altered as a consequence of connexin43 phosphorylation... - Light signaling in scotopic conditions in the rabbit, mouse and rat retina: a physiological and anatomical studyDario A Protti
Discipline of Physiology, School of Medical Sciences and Inst for Biomedical Research F13 The Univ of Sydney, NSW 2006, Australia
J Neurophysiol 93:3479-88. 2005..Our data support signaling through flat contacts between rods and off CB cells as the alternative route, but suggest that the significance of this pathway differs between species... - Strain-induced vascular endothelial cell proliferation requires PI3K-dependent mTOR-4E-BP1 signal pathwayWei Li
Dept. of Surgery, Yale University School of Medicine, 333 Cedar St, New Haven, CT 06520, USA
Am J Physiol Heart Circ Physiol 288:H1591-7. 2005..Cyclic strain also activated 4E-BP1, which could be inhibited by PI3K inhibitors. These data suggest that the PI3K-dependent S6K-mTOR-4E-BP1 signal pathway may be critically involved in strain-induced bovine aortic EC proliferation... - Evidence that ternary complex (eIF2-GTP-tRNA(i)(Met))-deficient preinitiation complexes are core constituents of mammalian stress granulesNancy Kedersha
Division of Rheumatology and Immunology, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA
Mol Biol Cell 13:195-210. 2002..We discuss these results in the context of a translational checkpoint model wherein TIA and eIF2 are functional antagonists of translational initiation, and in which lack of ternary complex drives SG assembly...