Research Topics
| R E LaskySummaryAffiliation: Baylor College of Medicine Country: USA Publications
Research Grants
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Detail Information
Publications
Early surfactant for neonates with mild to moderate respiratory distress syndrome: a multicenter, randomized trialMarilyn B Escobedo
University of Texas Southwestern Medical Center at Dallas (UTSW, Texas, USA
J Pediatr 144:804-8. 2004..CONCLUSIONS: Routine elective intubation for administration of surfactant to preterm infants >or=1250 grams with mild to moderate RDS is not recommended...
The effects of aggressive vs. conservative phototherapy on the brainstem auditory evoked responses of extremely-low-birth-weight infantsRobert E Lasky
Center for Clinical Research and Evidence Based Medicine, University of Texas Medical School at Houston, Houston, Texas, USA
Pediatr Res 71:77-84. 2012..conservative phototherapy on brainstem auditory evoked response (BAER) latencies in infants with extremely low birth weight (ELBW, ≤ 1,000 g)...- Predictors of interstitial lung disease in early systemic sclerosis: a prospective longitudinal study of the GENISOS cohortShervin Assassi
Division of Rheumatology and Clinical Immunogenetics, University of Texas Houston, 6431 Fannin, Houston, TX 77030, USA
Arthritis Res Ther 12:R166. 2010.... - Changes in the PQRST intervals and heart rate variability associated with rewarming in two newborns undergoing hypothermia therapyRobert E Lasky
Division of Neonatal Perinatal Medicine, Department of Pediatrics and Center for Clinical Research and Evidence Based Medicine, University of Texas Medical School, Houston, TX 77030, USA
Neonatology 96:93-5. 2009..Little is known about the effects of hypothermia therapy and subsequent rewarming on the PQRST intervals and heart rate variability (HRV) in term newborns with hypoxic-ischemic encephalopathy (HIE)... - The effects of early lead exposure on auditory function in rhesus monkeysR E Lasky
Center for Clinical Research and Evidence Based Medicine, University of Texas Houston Medical School, 6431 Fannin Street, MSB 2 106, Houston, TX 77030 1503, USA
Neurotoxicol Teratol 23:639-49. 2001..Finally, the auditory-evoked response at levels from the auditory nerve to the cerebral cortex did not significantly differ as a function of lead exposure. The lead exposure in this study had little effect on auditory function... - The effects of succimer chelation therapy on auditory function in rhesus monkeysR E Lasky
Center for Clinical Research and Evidence Based Medicine, The University of Texas Houston Medical School, 6431 Fannin Street, MSB 2 106, Houston, TX 77030 1503, USA
Neurotoxicol Teratol 23:651-8. 2001..4-10.0 kHz). Finally, the auditory evoked response at levels from the auditory nerve to the cerebral cortex did not significantly differ as a function of succimer treatment... - Perinatal exposure to Aroclor 1254 impairs distortion product otoacoustic emissions (DPOAEs) in ratsRobert E Lasky
Center for Clinical Research and Evidence Based Medicine, University of Texas Health Science Center at Houston Medical School, 6431 Fannin, MSB 2 104, Houston, Texas 77030 1503, USA
Toxicol Sci 68:458-64. 2002..In contrast, ABR latencies and amplitudes were not altered by A1254 exposure. These findings provide the first functional evidence supporting a cochlear site of damage in PCB-induced hearing loss... - Exploring a partially enclosed space by lead-exposed female rhesus monkeysR E Lasky
The Harlow Center for Biological Psychology, The University of Wisconsin Madison, Madison, WI, USA
Neurotoxicol Teratol 23:177-83. 2001..05 level of significance. The increased activity and agitation of the lead-exposed monkeys is suggestive of deficits reported in human children with high blood lead levels... - Noise and light exposures for extremely low birth weight newborns during their stay in the neonatal intensive care unitRobert E Lasky
University of Texas Medical School at Houston, Center for Clinical Research and Evidence Based Medicine, 6431 Fannin St, MSB 2 106, Houston, TX 77030, USA
Pediatrics 123:540-6. 2009.... - The effects of early lead exposure on the brains of adult rhesus monkeys: a volumetric MRI studyRobert E Lasky
Center for Clinical Research and Evidence Based Medicine, The University of Texas Houston Medical School, 6431 Fannin Street, MSB 2 104, Houston, Texas 77030, USA
Toxicol Sci 85:963-75. 2005..027) and left (p = 0.040) lateral ventricles. Depending on the timing of exposure during development, lead may exhibit differential effects with resultant life-long alterations in brain architecture... - The effects of elevated blood lead levels and succimer chelation therapy on physical growth in developing rhesus monkeysR E Lasky
Center for Clinical Research and Evidence-Based Medicine, The University of Texas-Houston Medical School, Houston, Texas 77030, USA
Environ Res 87:21-30. 2001..Growth in weight, length, and head circumference did not vary significantly as a function of blood lead levels. Succimer chelation therapy did not significantly affect weight, length, or head circumference through 2 years of age... - Longitudinal assessment of heart rate variability in very low birth weight infants during their NICU stayAsif Z Khattak
The University of Texas Medical School at Houston, Department of Pediatrics, 6431 Fannin Street, Houston, TX 77339, USA
Early Hum Dev 83:361-6. 2007..Maturation of the autonomic nervous system has not been studied in high-risk very low birth weight (VLBW) infants in the first few weeks of life... - Otoacoustic emission, evoked potential, and behavioral auditory thresholds in the rhesus monkey (Macaca mulatta)R E Lasky
Neurology Department, The University of Wisconsin Madison Medical School, H6 528 Clinical Science Building, 600 Highland Avenue, Madison, WI 53792 5132, USA
Hear Res 136:35-43. 1999..DPOAE and ABR thresholds can be reliably and efficiently recorded in the rhesus monkey and provide information concerning site of processing in the auditory pathway not directly available from behavioral data... - Evaluation of heterogeneity in pharmacotherapy trials for drug dependence: a Bayesian approachC E Green
Center for Clinical Research and Evidence Based Medicine, University of Texas, Houston, 77030, USA
Am J Drug Alcohol Abuse 35:95-102. 2009..Well-attested methodological difficulties associated with these analyses recommend the use of Bayesian statistical reasoning for evaluation of salient interaction effects... - Teaching teamwork during the Neonatal Resuscitation Program: a randomized trialE J Thomas
The University of Texas Center of Excellence for Patient Safety Research and Practice, Houston, TX 77030, USA
J Perinatol 27:409-14. 2007..We hypothesized that teams that received the new course would exhibit more teamwork behaviors than those in the standard NRP course... - Teamwork and quality during neonatal care in the delivery roomE J Thomas
Division of General Medicine, Department of Medicine, University of Texas Houston Medical School, Houston, TX 77030, USA
J Perinatol 26:163-9. 2006..Experts believe good teamwork among health care providers may improve quality. We sought to measure the frequency of team behaviors during delivery room care and to explore how these behaviors relate to the quality of care... - The behavioral pain response to heelstick in preterm neonates studied longitudinally: description, development, determinants, and componentsAmber L Williams
University of Texas Health Science Center at Houston, UT Houston Memorial Hermann Center for Healthcare Quality and Safety, Houston, Texas, USA
Early Hum Dev 85:369-74. 2009.... - A comparison of fetal and neonatal heart rate variability at similar post-menstrual agesNikhil S Padhye
The University of Texas Health Science Center at Houston, TX 77030, USA
Conf Proc IEEE Eng Med Biol Soc 2008:2801-4. 2008..Multiscale entropy was also higher in fetuses than in prematurely born neonates. These results suggest that the autonomic balance is poorer among neonates born prematurely than in fetuses of identical post-menstrual age... - Heart rate variability in response to pain stimulus in VLBW infants followed longitudinally during NICU stayNikhil S Padhye
Center for Nursing Research The University of Texas School of Nursing at Houston, 6901 Bertner Avenue Ste 560, P O Box 20334 Houston, TX 77225 0334, USA
Dev Psychobiol 51:638-49. 2009..There was some evidence that low-frequency HRV response to pain improved with advancing PMA... - Intensive care noise and mean arterial blood pressure in extremely low-birth-weight neonatesAmber L Williams
Center for Clinical Research and Evidence Based Medicine, University of Texas Medical School Houston, Houston, TX 77030, USA
Am J Perinatol 26:323-9. 2009..ELBW newborns in the first week of life seem to maintain a relatively stable blood pressure in response to moderate NICU sound levels (50 to 60 dBA)... - Effects of hypoxic-ischemic encephalopathy and whole-body hypothermia on neonatal auditory function: a pilot studyUlrike Mietzsch
Department of Pediatrics, Division of Neonatal Perinatal Medicine, University of Texas Medical School at Houston, Houston, Texas 77030, USA
Am J Perinatol 25:435-41. 2008..Neonatal audiometric testing is feasible, noninvasive, and capable of enhancing our understanding of the effects of HIE and hypothermia on auditory function... - Team training in the neonatal resuscitation program for interns: teamwork and quality of resuscitationsEric J Thomas
6410 Fannin St, UPB 1100, Houston, TX 77030, USA
Pediatrics 125:539-46. 2010..Our objective was to evaluate whether interns who received a 2-hour teamwork training intervention with the Neonatal Resuscitation Program (NRP) demonstrated more teamwork and higher quality resuscitations than control subjects... - Efficacy of intravitreal bevacizumab for stage 3+ retinopathy of prematurityHelen A Mintz-Hittner
Department of Ophthalmology and Visual Science, University of Texas Health Science Center at Houston Medical School, Houston, USA
N Engl J Med 364:603-15. 2011..Case series in which patients were treated with vascular endothelial growth factor inhibitors suggest that these agents may be useful in treating retinopathy of prematurity... - Noise in contemporary neonatal intensive careAmber L Williams
University of Texas Medical School Houston, Center for Clinical Research and Evidence Based Medicine, MSB 2 106, 6431 Fannin Street, Houston, Texas 77030, USA
J Acoust Soc Am 121:2681-90. 2007..3% of 5 s samples recorded from NICU A and 2.8% of NICU B samples. Twenty-four h periodicities in sound levels as a function of regular staff activities were apparent, but short-term variability was considerable... - Postnatal dexamethasone therapy and cerebral tissue volumes in extremely low birth weight infantsNehal A Parikh
Division of Neonatal Perinatal Medicine, Department of Pediatrics, University of Texas Medical School at Houston, Houston, TX 77030, USA
Pediatrics 119:265-72. 2007..Our goal was to relate postnatal dexamethasone therapy in extremely low birth weight infants (birth weight of < or = 1000 g) to their total and regional brain volumes, as measured by volumetric MRI performed at term-equivalent age... - Accuracy of the computer-aided surgical simulation (CASS) system in the treatment of patients with complex craniomaxillofacial deformity: A pilot studyJames J Xia
Surgical Planning Laboratory, Department of Oral and Maxillofacial Surgery, The Methodist Hospital Research Institute, Houston, TX 77096, USA
J Oral Maxillofac Surg 65:248-54. 2007..The purpose of this pilot study was to evaluate the accuracy of this technique in the treatment of patients with complex CMF deformities... - Defect size determines survival in infants with congenital diaphragmatic herniaKevin P Lally
University of Texas Medical School and Children s Memorial Hermann Hospital, USA
Pediatrics 120:e651-7. 2007..The objective of this study was to evaluate the clinical factors associated with death in infants with congenital diaphragmatic hernia by using a large multicenter data set... - Volumetric and anatomical MRI for hypoxic-ischemic encephalopathy: relationship to hypothermia therapy and neurosensory impairmentsN A Parikh
Division of Neonatal Perinatal Medicine, Department of Pediatrics, The University of Texas Medical School at Houston, Houston, TX 77030, USA
J Perinatol 29:143-9. 2009..To relate volumetric magnetic resonance imaging (MRI) findings to hypothermia therapy and neurosensory impairments... - Early lead exposure effects on an auditory threshold task in the rhesus monkey (Macaca mulatta)Nellie K Laughlin
Harlow Center for Biological Psychology, The University of Wisconsin Madison, Madison, Wisconsin 53715, USA
Dev Psychobiol 51:289-300. 2009..These results are consistent with reports concerning the behavior of lead exposed children... - Do former preterm infants remember and respond to neonatal intensive care unit noise?Edwin D Barreto
Department of Pediatrics, Division of Perinatal Neonatal Medicine, University of Texas Medical School at Houston, TX 77030, USA
Early Hum Dev 82:703-7. 2006..Previous studies have shown that 4-month-old infants have a decrease in heart rate, a component of the orienting reflex, in response to interesting auditory stimuli and an increase in heart rate to aversive auditory stimuli... - Postnatal lead effects on the development of visual spatial acuity in rhesus monkeys (Macaca Mulatta)Nellie K Laughlin
Harlow Center for Biological Psychology, The University of Wisconsin Madison, Madison, WI 53715, USA
Dev Psychobiol 50:608-14. 2008..3 c/deg) by 7 weeks of age for most monkeys. Postnatal lead exposure at the dosages and durations studied did not affect the development of photopic spatial acuity... - Long-term treatment effectiveness of molding helmet therapy in the correction of posterior deformational plagiocephaly: a five-year follow-upRobert P Lee
Department of Orthodontics, Dental Branch, The University of Texas Health Science Center, Houston, TX, USA
Cleft Palate Craniofac J 45:240-5. 2008..To evaluate the long-term effectiveness of helmet therapy in the correction of deformational plagiocephaly and to assess the early occlusal abnormalities seen in these patients... - Auditory deficits in rats exposed to an environmental PCB mixture during developmentBrian E Powers
Neuroscience Program, University of Illinois at Urbana-Champaign, Urbana, Illinois, 61802, USA
Toxicol Sci 89:415-22. 2006..Developmental exposure to PCBs may also result in subtle auditory impairments in humans, and if so, this may contribute to some of the cognitive deficits that have been observed in epidemiological studies... - Localization of brainstem auditory evoked potentials in primates: a comparison of localization techniques applied to deep brain sourcesJoel B Fontanarosa
Department of Pediatrics, The University of Chicago, Chicago, IL 60637, USA
Brain Topogr 17:99-108. 2004..The dipole methods performed better than LORETA and LCMV. Given the depth and amplitude of the sources analyzed in this study, these results can be interpreted as an upper bound on the accuracy of each technique...
Research Grants
- Effects of Noise on Newborns < 1000g BirthweightRobert Lasky; Fiscal Year: 2007..The research team consists of respected investigators skilled in assessing NICU noise, evaluating infant responses, and performing randomized trials addressing important short and long term outcomes of ELBW infants. ..