Research Topics
| Sunkuk KwonSummaryAffiliation: Baylor College of Medicine Country: USA Publications
| Collaborators
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Detail Information
Publications
In vivo dynamic imaging of intestinal motions using diet-related autofluorescenceS Kwon
Center for Molecular Imaging, The Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center, Houston, TX 77030, USA
Neurogastroenterol Motil 24:494-7. 2012..Herein, we non-invasively imaged for the first time intestinal motions, such as peristaltic and segmental motions, without an exogenous imaging agent, using red chlorophyll fluorescence...- Non-invasive, dynamic imaging of murine intestinal motilityS Kwon
Center for Molecular Imaging, The Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center, Houston, Texas 77030, USA
Neurogastroenterol Motil 23:881-e344. 2011..We sought to quantify the intestinal motility using dynamic NIR fluorescence imaging after injection of ICG... - Functional lymphatic imaging in tumor-bearing miceSunkuk Kwon
Center for Molecular Imaging, The Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center, 1825 Pressler Street, SRB 330A, Houston, TX 77030, USA
J Immunol Methods 360:167-72. 2010..Therefore, transient changes in the regional lymphatic architecture and function that occur with progressive disease, can be imaged using NIR fluorescence, and may provide a new method to stage disease... 
Dual-labeled trastuzumab-based imaging agent for the detection of human epidermal growth factor receptor 2 overexpression in breast cancerLakshmi Sampath
Division of Molecular Imaging, Department of Radiology, Baylor College of Medicine, Houston, TX 77030, USA
J Nucl Med 48:1501-10. 2007..The stoichiometric ratios "n" and "m" refer to the number of diethylenetriaminepentaacetic acid dianhydride (DTPA) and IRDye 800CW molecules bound per trastuzumab molecule, respectively...- Albumin-binding domain conjugate for near-infrared fluorescence lymphatic imagingCynthia A Davies-Venn
The Center for Molecular Imaging, The Brown Foundation Institute of Molecular Medicine, University of Texas Health Science Center, Houston, TX 77030, USA
Mol Imaging Biol 14:301-14. 2012.... 
Imaging prostate cancer lymph node metastases with a multimodality contrast agentMary A Hall
Center for Molecular Imaging, The Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center, Houston, Texas, USA
Prostate 72:129-46. 2012..Pelvic LN dissection is commonly performed during prostatectomy, but often followed by morbid complications. More refined methods for detecting LN invasion are needed...- Comparison of visible and near-infrared wavelength-excitable fluorescent dyes for molecular imaging of cancerKristen E Adams
Baylor College of Medicine, Department of Radiology, One Baylor Plaza, MS 360, Houston, Texas 77030, USA
J Biomed Opt 12:024017. 2007..5. Immunohistochemistry shows that EGF causes activation of the EGFr signaling pathway, suggesting that prior to use as a targeting, diagnostic agent, potential deleterious effects should be considered... - A new optical and nuclear dual-labeled imaging agent targeting interleukin 11 receptor alpha-chainWei Wang
Department of Radiology, Division of Molecular Imaging, Baylor College of Medicine, Houston, Texas 77030, USA
Bioconjug Chem 18:397-402. 2007..The cross validation and direct comparison of optical and nuclear imaging of a tumor was achieved using a single injection, and the preliminary results show the conjugate has tumor targeting capabilities in vivo... - In vivo fluorescent optical imaging of cytotoxic T lymphocyte migration using IRDye800CW near-infrared dyeAaron E Foster
Center for Cell and Gene Therapy, Baylor College of Medicine, Texas Children s Hospital, 1102 Bates Street, Houston, Texas 77030, USA
Appl Opt 47:5944-52. 2008..Together, these data suggest that IRDye800CW may be used to study the trafficking of T cells in a small animal model and may have potential as a short-term reporter molecule for human immunotherapy studies... - Assessment of free dye in solutions of dual-labeled antibody conjugates for in vivo molecular imagingMelissa B Aldrich
Division of Molecular Imaging, The Brown Foundation Institute of Molecular Medicine, University of Texas Health Sciences Center Houston, Houston, TX, USA
Mol Imaging Biol 13:32-42. 2011..A method for quantifying free dye molecules in antibody conjugate preparations is required for agent batch release and for translation into the clinic... - Noninvasive quantitative imaging of lymph function in miceSunkuk Kwon
Division of Molecular Imaging, Department of Radiology, Baylor College of Medicine, Houston, TX 77030 3411, USA
Lymphat Res Biol 5:219-31. 2007..Herein, we present a noninvasive and rapid approach to measure lymphatic function in a rodent model using a near-infrared (NIR) dye to minimize background autofluorescence and maximize tissue penetration... - The role of lymphatics in cancer as assessed by near-infrared fluorescence imagingJohn C Rasmussen
Center for Molecular Imaging, The Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center, Houston, TX 77030, USA
Ann Biomed Eng 40:408-21. 2012..We then present recent NIRF lymphatic imaging for non-invasive assessment of lymphatics both in preclinical melanoma models and in human subjects with melanoma... - Human Lymphatic Architecture and Dynamic Transport Imaged Using Near-infrared FluorescenceJohn C Rasmussen
Center for Molecular Imaging, The Brown Foundation Institute of Molecular Medicine at the University of Texas Health Science Center at Houston, Houston, TX, USA
Transl Oncol 3:362-72. 2010.... - Quantitative imaging of lymph functionRuchi Sharma
Division of Molecular Imaging, Department of Radiology, Baylor College of Medicine, Houston, TX 77030, USA
Am J Physiol Heart Circ Physiol 292:H3109-18. 2007..Our results suggest that microgram quantities of NIR optical imaging agents and their conjugates have a potential to image lymph function in patients suffering from lymph-related disorders... - Altered lymphatic function and architecture in salt-induced hypertension assessed by near-infrared fluorescence imagingSunkuk Kwon
University of Texas Health Science Center, Center for Molecular Imaging, The Brown Foundation Institute of Molecular Medicine, Houston, Texas 77030
J Biomed Opt 17:80504-1. 2012..Lymphatic contractile function and vessel remodeling occurs in response to salt-induced hypertension suggesting a possible role for the lymphatics in the regulation of vascular blood pressure... - Characterization of chemical, radiochemical and optical properties of a dual-labeled MMP-9 targeting peptideAli Azhdarinia
Center for Molecular Imaging, The Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center, Houston, TX 77030, USA
Bioorg Med Chem 19:3769-76. 2011..This attests to the feasibility of using (68)Ga/NIR for dual-labeling of other peptides or small molecules for multimodality molecular imaging... - Virus-like particle (VLP) lymphatic trafficking and immune response generation after immunization by different routesRafael Cubas
Division of Vascular Surgery and Endovascular Therapy, Michael E DeBakey Department of Surgery, Baylor College of Medicine, Frensley Center for Imaging Research, Houston, TX 77030, USA
J Immunother 32:118-28. 2009..Intradermal immunization showed improved responses and might be a preferable delivery route to use for viral and cancer immunotherapeutic studies involving VLPs... - Detection of Cancer Metastases with a Dual-labeled Near-Infrared/Positron Emission Tomography Imaging AgentLakshmi Sampath
Center for Molecular Imaging, Institute of Molecular Medicine, University of Texas Health Science Center, Houston, TX, USA
Transl Oncol 3:307-217. 2010.... - Mouse phenotyping with near-infrared fluorescence lymphatic imagingSunkuk Kwon
Center for Molecular Imaging, The Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, Houston, TX 77584, USA
Biomed Opt Express 2:1403-11. 2011..NIR fluorescence imaging provides a method for quantifying lymphatic function for future studies designed to discern differences in lymphatic function in murine models of human lymphatic disease...