Research Topics
| Alana A Kennedy-NasserSummaryAffiliation: Baylor College of Medicine Country: USA Publications
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Detail Information
Publications
Comparable outcomes of matched-related and alternative donor stem cell transplantation for pediatric severe aplastic anemiaAlana A Kennedy-Nasser
Center for Cell and Gene Therapy, Baylor College of Medicine, The Methodist Hospital and Texas Children s Hospital, Houston, Texas 77030, USA
Biol Blood Marrow Transplant 12:1277-84. 2006..We conclude that, for children with SAA, AD transplantation is as effective as MSD transplantation. Further, compared with ATG, preparatory regimens containing Campath may be associated with a lower incidence of extensive, chronic GHVD...
T-cell therapy after hematopoietic stem cell transplantationAlana A Kennedy-Nasser
Center for Cell and Gene Therapy, Baylor College of Medicine, Houston, Texas 77030, USA
Curr Opin Hematol 14:616-24. 2007..We describe how an improved understanding of T-cell mediated graft versus leukemia and of antiviral responses is providing effective approaches to T-cell immunotherapy...
Comparable outcome of alternative donor and matched sibling donor hematopoietic stem cell transplant for children with acute lymphoblastic leukemia in first or second remission using alemtuzumab in a myeloablative conditioning regimenAlana A Kennedy-Nasser
Center for Cell and Gene Therapy, Baylor College of Medicine, Texas Children s Hospital, Houston, Texas 77030, USA
Biol Blood Marrow Transplant 14:1245-52. 2008..For children undergoing stem cell transplantation (SCT) from alternative donors, alemtuzumab with a myeloablative conditioning regimen resulted in DFS comparable to MSD...
The costs and cost-effectiveness of allogeneic peripheral blood stem cell transplantation versus bone marrow transplantation in pediatric patients with acute leukemiaYu Feng Lin
Center for Cell and Gene Therapy, Department of Pediatrics, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA
Biol Blood Marrow Transplant 16:1272-81. 2010..More studies using larger and randomized controlled trials are needed to confirm the long-term cost-effectiveness of each procedure...
Cytotoxic T lymphocyte therapy with donor T cells prevents and treats adenovirus and Epstein-Barr virus infections after haploidentical and matched unrelated stem cell transplantationAnn M Leen
Center for Cell and Gene Therapy and Departments of Pediatrics, Immunology, Medicine, and Virology, Baylor College of Medicine, Texas Children s Hospital and The Methodist Hospital, Houston, TX 77030, USA
Blood 114:4283-92. 2009..This trial was registered at www.clinicaltrials.gov as #NCT00590083...
Children with acute leukemia: a comparison of outcomes from allogeneic blood stem cell and bone marrow transplantationYu Feng Lin
Center for Cell and Gene Therapy, Department of Pediatrics, Baylor College of Medicine, Houston, Texas 77030, USA
Pediatr Blood Cancer 56:143-51. 2011..In a retrospective study, we compared allogeneic PBSCT (n = 30) with BMT (n = 110) in children with acute leukemia between January 2001 and September 2006...
Hodgkin disease and the role of the immune systemAlana A Kennedy-Nasser
Baylor College of Medicine, Texas Children s Hospital, TX, USA
Pediatr Hematol Oncol 28:176-86. 2011..Specifically, the authors closely evaluate the roles of regulatory T cells in HD, cytotoxic T cells, cytokine and chemokine secretion, down-regulation of Fas ligand, and indoleamine 2,3-dioxygenase (IDO) secretion...
Immunotherapy for epstein-barr virus-related lymphomasAlana A Kennedy-Nasser
Center for Cell and Gene Therapy, Baylor College of Medicine, Texas Children s Hospital and The Methodist Hospital, Houston
Mediterr J Hematol Infect Dis 1:e2009010. 2009..We review the current immunotherapies and future studies aimed at targeting EBV antigen expression in these tumors...
Adoptive immunotherapy for Hodgkin's lymphomaAlana A Kennedy-Nasser
Center for Cell and Gene Therapy, Baylor College of Medicine, The Methodist Hospital and Texas Children's Hospital, Houston, Texas 77030, USA
Int J Hematol 83:385-90. 2006..In this article, we discuss the promise of Epstein-Barr virus-specific cytotoxic T-lymphocytes, the roles of cytokines, and other strategies for overcoming the immune-evasion mechanisms in Hodgkin's lymphoma...
