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Genomes and GenesSpecies | Zhi Dong JiangSummaryAffiliation: Baylor College of Medicine Country: USA Publications
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Publications
Association of interleukin-8 polymorphism and immunoglobulin G anti-toxin A in patients with Clostridium difficile-associated diarrheaZhi Dong Jiang
Center for Infectious Diseases, 1200 Herman Pressler, Room 739, University of Texas School of Public Health, Houston, Texas 77030, USA
Clin Gastroenterol Hepatol 5:964-8. 2007..This study examined the relationship between serum immunoglobulin G antibodies to CD toxin A and the presence of IL-8 AA genotype in hospitalized patients with CDAD...- Treatment of travelers' diarrhea: randomized trial comparing rifaximin, rifaximin plus loperamide, and loperamide aloneHerbert L DuPont
Center for Infectious Diseases, University of Texas School of Public Health, Houston, Texas, USA
Clin Gastroenterol Hepatol 5:451-6. 2007..This study evaluated the efficacy and safety of rifaximin-loperamide in the treatment of travelers' diarrhea... 
Association of putative enteroaggregative Escherichia coli virulence genes and biofilm production in isolates from travelers to developing countriesJamal A Mohamed
Division of Infectious Diseases, Department of Internal Medicine, University of Texas Medical School, Houston, TX 77030, USA
J Clin Microbiol 45:121-6. 2007..This study suggests that biofilm formation is a common phenomenon among EAEC isolates derived from travelers with or without diarrhea and that multiple genes associated with biofilm formation are regulated by aggR...- Noroviruses as a cause of diarrhea in travelers to Guatemala, India, and MexicoHoonmo L Koo
Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA
J Clin Microbiol 48:1673-6. 2010..Significant variation in the prevalence of NoV diarrhea and in the predominant genogroup infecting travelers was demonstrated, dependent upon the specific geographic location and over time... - A single-nucleotide polymorphism in the gene encoding osteoprotegerin, an anti-inflammatory protein produced in response to infection with diarrheagenic Escherichia coli, is associated with an increased risk of nonsecretory bacterial diarrhea in North AmeJamal A Mohamed
Division of Infectious Diseases, The University of Texas Medical School, Center for Infectious Diseases, Baylor College of Medicine, Houston, TX, USA
J Infect Dis 199:477-85. 2009.... - Enterotoxigenic Escherichia coli heat-labile toxin seroconversion in US travelers to MexicoJose Flores
Division of Infectious Diseases, University of Texas Medical School at Houston, Houston, TX 77030, USA
J Travel Med 15:156-61. 2008..However, the role of LT-producing ETEC (LT-ETEC) as a cause of diarrhea is controversial. We conducted a cohort study in US students traveling to Mexico to assess the ETEC-LT seroconversion rate after natural exposure... - Rate of occurrence and pathogenic effect of enteroaggregative Escherichia coli virulence factors in international travelersZhi Dong Jiang
The University of Texas Health Science Center School of Public Health, Houston, Texas 77030, USA
J Clin Microbiol 40:4185-90. 2002..The different patterns of virulence factors of EAEC revealed several clusters demonstrating diversity among the isolates from the various regions... - Genetic susceptibility to enteroaggregative Escherichia coli diarrhea: polymorphism in the interleukin-8 promotor regionZhi Dong Jiang
University of Texas School of Public Health, Houston, Texas, USA
J Infect Dis 188:506-11. 2003..0053). In the present study, the AA genotype at the -251 position was associated with the occurrence of EAEC-associated diarrhea and increased levels of fecal IL-8... - A randomized, double-blind, placebo-controlled trial of rifaximin to prevent travelers' diarrheaHerbert L DuPont
University of Texas Houston, Baylor College of Medicine, St Luke s Episcopal Hospital, and M D Anderson Cancer Center, Houston, Texas 77030, USA
Ann Intern Med 142:805-12. 2005..Travelers' diarrhea causes substantial morbidity and postinfectious irritable bowel syndrome... - PCR-based assay using occult blood detection cards for detection of diarrheagenic Escherichia coli in specimens from U.S. travelers to Mexico with acute diarrheaKevin A Grimes
Division of Infectious Diseases, The University of Texas Medical School, Houston, Texas, USA
J Clin Microbiol 46:2227-30. 2008..DNA extracted from fecal cards that was used for the detection of occult blood is of use in identifying diarrheagenic E. coli... - Single nucleotide polymorphisms in the promoter of the gene encoding the lipopolysaccharide receptor CD14 are associated with bacterial diarrhea in US and Canadian travelers to MexicoJamal A Mohamed
Department of Internal Medicine, Division of Infectious Diseases University of Texas Medical School at Houston, Houston, TX 77030, USA
Clin Infect Dis 52:1332-41. 2011.... - Epidemiology of cryptosporidiosis in North American travelers to MexicoParvathy Nair
The University of Texas Health Science Center at Houston Medical School and School of Public Health, Houston, Texas, USA
Am J Trop Med Hyg 79:210-4. 2008..Speciation by 18SrRNA sequencing showed that 13 cases were caused by C. parvum and only 1 case was caused by C. hominis. ELISA showed a sensitivity of 50% and specificity of 100% compared with PCR... - Campylobacter jejuni is not an important pathogen as a cause of diarrhea in US travelers to MexicoNicolas A Villa
Baylor College of Medicine, Houston, TX, USA
J Travel Med 18:56-8. 2011..Serum IgG, IgA, and IgM antibodies to Campylobacter seroconverted in only 2 of 353 participants (0.6%). These data further support that C jejuni infection is an unusual cause of travelers' diarrhea in US visitors to Mexico... - A randomized, double-blind, placebo-controlled pilot study to assess the ability of rifaximin to prevent recurrent diarrhoea in patients with Clostridium difficile infectionKevin W Garey
University of Houston College of Pharmacy, 1441 Moursund Street, Houston, TX 77030, USA
J Antimicrob Chemother 66:2850-5. 2011..15). Conclusions Patients with CDI given a rifaximin chaser regimen experienced a decreased incidence of recurrent diarrhoea compared with placebo... - Antibacterial chemoprophylaxis in the prevention of traveler's diarrhea: evaluation of poorly absorbed oral rifaximinHerbert L DuPont
Houston School of Public Health, Houston, TX, USA
Clin Infect Dis 41:S571-6. 2005.... - Virulence characteristics and the molecular epidemiology of enteroaggregative Escherichia coli isolates from travellers to developing countriesDavid B Huang
Baylor College of Medicine, Division of Infectious Diseases, Houston, TX, USA
J Med Microbiol 56:1386-92. 2007.... - Enterotoxigenic Escherichia coli and diffusely adherent E. coli as likely causes of a proportion of pathogen-negative travelers' diarrhea--a PCR-based studyIsmail M Meraz
School of Public Health, University of Texas, Houston, TX 77030, USA
J Travel Med 15:412-8. 2008..Enteropathogens cannot be identified in 40% to 50% of subjects with travelers' diarrhea (TD)... - Association of virulence factor-positive and -negative enteroaggregative Escherichia coli and occurrence of clinical illness in travelers from the United States to MexicoDavid B Huang
Department of Medicine, Baylor College of Medicine, Houston, Texas 77030, USA
Am J Trop Med Hyg 69:506-8. 2003..Our study suggests that clinical illness by EAEC is not explained by presence of a defined EAEC virulence factors, and we provide suggestive evidence that EAEC infection protects against future symptomatic infection... - Rifaximin-induced alteration of virulence of diarrhoea-producing Escherichia coli and Shigella sonneiZhi Dong Jiang
Center for Infectious Diseases, The University of Texas School of Public Health, 1200 Herman Pressler, Room 706, Houston, TX 77030, USA
Int J Antimicrob Agents 35:278-81. 2010..At subinhibitory concentrations, rifaximin alters the virulence of ETEC, EAEC and S. sonnei isolates. These findings help explain the efficacy of rifaximin despite minimal alteration of colonic flora... 
A randomized, double-blind, pilot study of rifaximin 550 mg versus placebo in the prevention of travelers' diarrhea in Mexico during the dry seasonJose Flores
Center for Infectious Diseases, School of Public Health, The University of Texas Health Science Center at Houston, TX, USA
J Travel Med 18:333-6. 2011..Rifaximin has been shown to be effective in treating and preventing travelers' diarrhea (TD) during the summer season...- In vitro antimicrobial susceptibility of bacterial enteropathogens isolated from international travelers to Mexico, Guatemala, and India from 2006 to 2008Jeannette Ouyang-Latimer
Baylor College of Medicine, Houston, Texas, USA
Antimicrob Agents Chemother 55:874-8. 2011..There were no significant changes in rifaximin MICs. Rising MICs over time imply the need for continuous surveillance of susceptibility patterns worldwide and geographically specific recommendations in TD therapy... - Clostridium difficile infection: update on emerging antibiotic treatment options and antibiotic resistanceDhara Shah
University of Houston College of Pharmacy, 1441 Moursund Street, Houston, TX 77030, USA
Expert Rev Anti Infect Ther 8:555-64. 2010..This review will focus primarily on scientific studies published in the last 36 months in order to provide an up-to-date review on the topic... - Loperamide plus azithromycin more effectively treats travelers' diarrhea in Mexico than azithromycin aloneCharles D Ericsson
Department of Medicine, Division of Infectious Diseases, University of Texas Medical School at Houston, and St Luke s Episcopal Hospital, Houston, TX 77030, USA
J Travel Med 14:312-9. 2007.... - Prevalence of enteric pathogens among international travelers with diarrhea acquired in Kenya (Mombasa), India (Goa), or Jamaica (Montego Bay)Zhi Dong Jiang
Center for Infectious Diseases, University of Texas Houston School of Public Health, Houston, TX 77030, USA
J Infect Dis 185:497-502. 2002..Quinolones were active against the bacterial enteropathogens in the 3 sites... - A novel single-nucleotide polymorphism in the lactoferrin gene is associated with susceptibility to diarrhea in North American travelers to MexicoJamal A Mohamed
Division of Infectious Diseases, The University of Texas Medical School, Houston, TX 77030, USA
Clin Infect Dis 44:945-52. 2007..We investigated the impact that selected single-nucleotide polymorphisms (SNPs) in the human lactoferrin gene have on susceptibility to traveler's diarrhea... - Improvement in detection of enterotoxigenic Escherichia coli in patients with travelers' diarrhea by increasing the number of E. coli colonies testedThushara Galbadage
The University of Texas School of Public Health at Houston, Houston, TX 77225, USA
Am J Trop Med Hyg 80:20-3. 2009..0%), 37 (31.9%), 45 (38.8%) and 46 (39.7%), respectively. Based on our results, we recommend the testing of at least 10 E. coli colonies for optimum detection of ETEC in patients with TD... - Natural history of enteroaggregative and enterotoxigenic Escherichia coli infection among US travelers to Guadalajara, MexicoJavier A Adachi
Center for Infectious Diseases, Medical School and School of Public Health, University of Texas-Houston, Houston, TX, USA
J Infect Dis 185:1681-3. 2002..Symptomatic EAEC infection occurred early after arrival in Guadalajara, Mexico, and was as common as ETEC infection. Asymptomatic EAEC infection was recurrent... - New advances in Clostridium difficile infection: changing epidemiology, diagnosis, treatment and controlHerbert L DuPont
The University of Texas School of Public Health, Houston, Texas 77030, USA
Curr Opin Infect Dis 21:500-7. 2008..The present review focuses on scientific papers published in the past 18 months in an attempt to provide the latest information on the topic... - Rifaximin treatment of pathogen-negative travelers' diarrheaHerbert L DuPont
Center for Infectious Diseases, Houston School of Public Health, The University of Texas, Houston, TX, USA
J Travel Med 14:16-9. 2007..Antibacterial drugs appear to be effective in shortening the illness of a majority of cases of travelers' diarrhea... - A common polymorphism in the interleukin-8 gene promoter is associated with an increased risk for recurrent Clostridium difficile infectionKevin W Garey
University of Houston College of Pharmacy, Houston, Texas, USA
Clin Infect Dis 51:1406-10. 2010..We hypothesized that a common single-nucleotide polymorphism (SNP) in the -251 region of the IL-8 gene promoter may be predictive of recurrent CDI... - Coliform contamination of vegetables obtained from popular restaurants in Guadalajara, Mexico, and Houston, TexasHoonmo L Koo
Baylor College of Medicine, University of Texas Health Science Center at Houston, Houston, Texas, USA
Clin Infect Dis 47:218-21. 2008..Prevention of traveler's diarrhea by avoidance of "high-risk" foods may be unsuccessful, because contamination of foods may occur regardless of how they are prepared... - Phylogenetic comparisons reveal multiple acquisitions of the toxin genes by enterotoxigenic Escherichia coli strains of different evolutionary lineagesSue M Turner
Division of Immunity and Infection, The Medical School, The University of Birmingham, Edgbaston, Birmingham B15 2TT, United Kingdom, and St. Luke's Episcopal Hospital, Houston, TX 77083, USA
J Clin Microbiol 44:4528-36. 2006..coli revealed that they were not abundant. These observations have significant implications for disease epidemiology and for the design of effective vaccines... - Post-diarrhea chronic intestinal symptoms and irritable bowel syndrome in North American travelers to MexicoPablo C Okhuysen
Division of Infectious Diseases, Medical School, The University of Texas Health Science Center at Houston, 6431 Fannin, JFB 1.728, Houston, TX 77096, USA
Am J Gastroenterol 99:1774-8. 2004..Postinfectious complications of traveler's diarrhea require further study for etiology and strategy for prevention... - Microbial etiology of travelers' diarrhea in Mexico, Guatemala, and India: importance of enterotoxigenic Bacteroides fragilis and Arcobacter speciesZhi Dong Jiang
Center for Infectious Diseases, University of Texas School of Public Health, 1200 Herman Pressler Room 741, Houston, TX 77030, USA
J Clin Microbiol 48:1417-9. 2010..S. and European travelers with acute diarrhea acquired in Mexico, Guatemala, and India. Arcobacter butzleri and ETBF were detected in 8% and 7% of diarrhea cases, respectively... - Peripartum Clostridium difficile infection: case series and review of the literatureKevin W Garey
Texas Medical Center, University of Houston College of Pharmacy, Houston, TX 77030, USA
Am J Obstet Gynecol 199:332-7. 2008..Further research into the scope and risk factors for peripartum CDI is warranted... - Travel and travelers' diarrhea in patients with irritable bowel syndromeHerbert L DuPont
University of Texas School of Public Health, Houston, TX, USA
Am J Trop Med Hyg 82:301-5. 2010..Symptoms of established functional bowel disorder in each clinical category were shown to worsen after travel-related acute diarrhea... - Markers of inflammation in bacterial diarrhea among travelers, with a focus on enteroaggregative Escherichia coli pathogenicityDavid E Greenberg
Baylor College of Medicine, Houston, Texas, USA
J Infect Dis 185:944-9. 2002..Bacterial pathogens causing traveler's diarrhea commonly produce intestinal inflammation, although a subset of patients with EAEC-associated diarrhea fail to develop an inflammatory response... - Azithromycin found to be comparable to levofloxacin for the treatment of US travelers with acute diarrhea acquired in MexicoJavier A Adachi
Center for Infectious Diseases, University of Texas-Houston School of Public Health and Medical School, Houston, Texas, USA
Clin Infect Dis 37:1165-71. 2003..Azithromycin was found to be a safe and effective alternative to levofloxacin for the treatment of acute travelers' diarrhea in US adult travelers to Mexico... - Interleukin-8 response in an intestinal HCT-8 cell line infected with enteroaggregative and enterotoxigenic Escherichia coliDavid B Huang
University of Texas Health Science Center, Houston Medical School, 6431 Fannin, JFB 1.728, Houston, TX 77030, USA
Clin Diagn Lab Immunol 11:548-51. 2004.... - Bile acids improve the antimicrobial effect of rifaximinCharles Darkoh
University of Texas Graduate School of Biomedical Sciences, Houston, TX, USA
Antimicrob Agents Chemother 54:3618-24. 2010..The water insolubility of rifaximin is the likely explanation for the drug's minimal effects on colonic flora and fecal pathogens, despite in vitro susceptibility... - Changing Clostridium difficile infection testing and treatment trends at a large tertiary care teaching hospitalMiguel Salazar
St Luke s Episcopal Hospital, Houston, TX 77030, USA
Pharm World Sci 31:565-71. 2009..To assess changes in testing and treatment trends of CDI at a time when the Clostridium difficile hypervirulent strain was first identified... - Pretreatment of epithelial cells with rifaximin alters bacterial attachment and internalization profilesEric L Brown
The University of Texas School of Public Health, 1200 Herman Pressler, Houston, TX 77030, USA
Antimicrob Agents Chemother 54:388-96. 2010..The study provides evidence that rifaximin-mediated changes in epithelial cell physiology are associated with changes in bacterial attachment/internalization and reduced inflammatory cytokine release... - Enteroaggregative Escherichia coli diarrhea in travelers: response to rifaximin therapyRosa M Infante
Center for Infectious Diseases, The University of Texas-Houston School of Public Health and Medical School, Houston, Texas, USA
Clin Gastroenterol Hepatol 2:135-8. 2004..The study provides information on the value of the poorly absorbed drug rifaximin in therapy of travelers' diarrhea... - Enteroaggregative Escherichia coli: an emerging enteric pathogenDavid B Huang
Department of Medicine, Baylor College of Medicine, Houston, Texas, USA
Am J Gastroenterol 99:383-9. 2004..The objective of this review is to increase awareness of this important emerging pathogen and to discuss the epidemiology, pathogenesis, and host-pathogen factors associated with EAEC infection... - Enteric pathogens in Mexican sauces of popular restaurants in Guadalajara, Mexico, and Houston, TexasJavier A Adachi
University of Texas, St. Luke's Episcopal Hospital, and Baylor College of Medicine, Houston, Texas 77030, USA
Ann Intern Med 136:884-7. 2002..coli and 14 of 32 contained enteroaggregative E. coli. CONCLUSIONS: Contamination with E. coli was common in samples of Mexican tabletop sauces from Guadalajara restaurants. These sauces commonly contained enteric pathogens... - United States male students who heavily consume alcohol in Mexico are at greater risk of travelers' diarrhea than their female counterpartsDavid B Huang
Department of Medicine, Baylor College of Medicine, Houston, TX, USA
J Travel Med 11:143-5. 2004..Nondrinkers also deserve further study in larger numbers to confirm an apparently high attack rate of diarrhea and to explore what risk factors might be involved... - Enterotoxigenic Escherichia coli as cause of diarrhea among Mexican adults and US travelers in MexicoAlain R Bouckenooghe
Veterans Affairs Medical Center, Baylor College of Medicine, and University of Texas Medical School and School of Public Health, Houston, Texas, USA
J Travel Med 9:137-40. 2002..0004), as was the average number of unformed stools passed over 4 days (Mexicans 8.8 versus travelers 17.9 stools; p =.0009.. - A nosocomial outbreak of norovirus infection masquerading as clostridium difficile infectionHoonmo L Koo
Baylor College of Medicine, University of Texas Houston School of Public Health, Houston, Texas, USA
Clin Infect Dis 48:e75-7. 2009..We describe here the unique challenges of the identification of NoVs as the true etiologic pathogen in an outbreak occurring in a health care setting, where C. difficile infection is endemic, as well as the important lessons learned... - Detection of enteroaggregative Escherichia coli with formalin-preserved HEp-2 cellsMohamad S Miqdady
Baylor College of Medicine, Houston, Texas, USA
J Clin Microbiol 40:3066-7. 2002..Using formalin-fixed HEp-2 cells will improve the efficiency of EAEC identification... - Clostridium difficile infection in patients with ileal pouch-anal anastomosisB O Shen
Center for Inflammatory Bowel Disease, Department of Gastroenterology Hepatology, The Cleveland Clinic Foundation, Cleveland, Ohio, USA
Clin Gastroenterol Hepatol 6:782-8. 2008..S. The importance of C difficile infection in patients with ileal pouch-anal anastomosis (IPAA) is unknown. This study was designed to determine risk of acquiring C difficile infection in pouch disorders... - Use of a patch containing heat-labile toxin from Escherichia coli against travellers' diarrhoea: a phase II, randomised, double-blind, placebo-controlled field trialSarah A Frech
IOMAI Corporation, Gaithersburg, MD, USA
Lancet 371:2019-25. 2008..We investigated the rate of diarrhoea attacks, safety, and feasibility of a vaccine containing heat-labile enterotoxin (LT) from ETEC delivered to the skin by patch in travellers to Mexico and Guatemala... - Noroviruses as a cause of traveler's diarrhea among students from the United States visiting MexicoGwangpyo Ko
Department of Environmental Health, School of Public Health, Seoul National University, 28 Yunkeun dong, ChongRo Ku, Seoul 110 799, South Korea
J Clin Microbiol 43:6126-9. 2005..This study indicates that NoV is an underappreciated cause of traveler's diarrhea... - A randomized, double-blind, multicenter study of rifaximin compared with placebo and with ciprofloxacin in the treatment of travelers' diarrheaDavid N Taylor
Salix Pharmaceuticals, Inc, Morrisville, North Carolina, USA
Am J Trop Med Hyg 74:1060-6. 2006..35 versus rifaximin). Rifaximin was less effective than ciprofloxacin for invasive intestinal bacterial pathogens. Oral rifaximin is a safe and effective treatment of travelers' diarrhea caused by noninvasive pathogens... - A common polymorphism in the interleukin 8 gene promoter is associated with Clostridium difficile diarrheaZhi Dong Jiang
The University of Texas School of Public Health, USA
Am J Gastroenterol 101:1112-6. 2006..We hypothesized that like other inflammatory mucosal infections, susceptibility to CDD would relate to genetically determined variations in the production of IL-8... - Fecal cytokines and markers of intestinal inflammation in international travelers with diarrhea due to NorovirusesGwangpyo Ko
Seoul National University, School of Public Health, Institute of Health and Environment, Seoul, Korea
J Med Virol 78:825-8. 2006..Intestinal inflammation associated with increased fecal lactoferrin, important in bacterial enteric infection, was not found in NoV-associated gastroenteritis... - Identification of compounds that inhibit late steps of peptidoglycan synthesis in bacteriaMaureen DeCenzo
Millennium Pharmaceuticals, Inc, Cambridge, MA, USA
J Antibiot (Tokyo) 55:288-95. 2002..This screening system proved to be especially useful because it was sufficiently sensitive and robust to detect inhibitors among samples of crude preparations or varying states of purity...