Henry H Jerng

Summary

Affiliation: Baylor College of Medicine
Country: USA

Publications

  1. pmc Incorporation of DPP6a and DPP6K variants in ternary Kv4 channel complex reconstitutes properties of A-type K current in rat cerebellar granule cells
    Henry H Jerng
    Department of Neuroscience, Baylor College of Medicine, Houston, Texas, United States of America
    PLoS ONE 7:e38205. 2012
  2. pmc Multiprotein assembly of Kv4.2, KChIP3 and DPP10 produces ternary channel complexes with ISA-like properties
    Henry H Jerng
    Department of Neuroscience, Baylor College of Medicine, One Baylor Plaza, S630, Houston, TX 77030, USA
    J Physiol 568:767-88. 2005
  3. pmc DPP10 splice variants are localized in distinct neuronal populations and act to differentially regulate the inactivation properties of Kv4-based ion channels
    Henry H Jerng
    Department of Neuroscience, Baylor College of Medicine, One Baylor Plaza, S630 Houston, TX 77030, USA
    Mol Cell Neurosci 35:604-24. 2007
  4. pmc A novel N-terminal motif of dipeptidyl peptidase-like proteins produces rapid inactivation of KV4.2 channels by a pore-blocking mechanism
    Henry H Jerng
    Department of Neuroscience, Baylor College of Medicine, Houston, TX, USA
    Channels (Austin) 3:448-61. 2009
  5. pmc Multiple Kv channel-interacting proteins contain an N-terminal transmembrane domain that regulates Kv4 channel trafficking and gating
    Henry H Jerng
    Department of Neuroscience, Baylor College of Medicine, Houston, Texas 77030, USA
    J Biol Chem 283:36046-59. 2008
  6. ncbi request reprint Molecular physiology and modulation of somatodendritic A-type potassium channels
    Henry H Jerng
    Division of Neuroscience, Baylor College of Medicine, Houston, TX 77030, USA
    Mol Cell Neurosci 27:343-69. 2004
  7. pmc Modulation of Kv4.2 channel expression and gating by dipeptidyl peptidase 10 (DPP10)
    Henry H Jerng
    Division of Neuroscience, Baylor College of Medicine, Houston, Texas 77030, USA
    Biophys J 87:2380-96. 2004
  8. pmc S-glutathionylation of an auxiliary subunit confers redox sensitivity to Kv4 channel inactivation
    Henry H Jerng
    Department of Neuroscience, Baylor College of Medicine, Houston, Texas, United States of America
    PLoS ONE 9:e93315. 2014

Collaborators

Detail Information

Publications9

  1. pmc Incorporation of DPP6a and DPP6K variants in ternary Kv4 channel complex reconstitutes properties of A-type K current in rat cerebellar granule cells
    Henry H Jerng
    Department of Neuroscience, Baylor College of Medicine, Houston, Texas, United States of America
    PLoS ONE 7:e38205. 2012
    ..Our results support the hypothesis that the precise expression and co-assembly of different auxiliary subunit variants are important factors in shaping the I(SA) functional properties in specific neuronal populations...
  2. pmc Multiprotein assembly of Kv4.2, KChIP3 and DPP10 produces ternary channel complexes with ISA-like properties
    Henry H Jerng
    Department of Neuroscience, Baylor College of Medicine, One Baylor Plaza, S630, Houston, TX 77030, USA
    J Physiol 568:767-88. 2005
    ....
  3. pmc DPP10 splice variants are localized in distinct neuronal populations and act to differentially regulate the inactivation properties of Kv4-based ion channels
    Henry H Jerng
    Department of Neuroscience, Baylor College of Medicine, One Baylor Plaza, S630 Houston, TX 77030, USA
    Mol Cell Neurosci 35:604-24. 2007
    ..Our results suggest that DPP10a underlies rapid inactivation of cortical I(SA), and the regulation of isoform expression may contribute to the variable inactivation properties of I(SA) across different brain regions...
  4. pmc A novel N-terminal motif of dipeptidyl peptidase-like proteins produces rapid inactivation of KV4.2 channels by a pore-blocking mechanism
    Henry H Jerng
    Department of Neuroscience, Baylor College of Medicine, Houston, TX, USA
    Channels (Austin) 3:448-61. 2009
    ..This mechanism may offer an attractive target for novel pharmacological interventions directed at impairing I(SA) inactivation and reducing neuronal excitability...
  5. pmc Multiple Kv channel-interacting proteins contain an N-terminal transmembrane domain that regulates Kv4 channel trafficking and gating
    Henry H Jerng
    Department of Neuroscience, Baylor College of Medicine, Houston, Texas 77030, USA
    J Biol Chem 283:36046-59. 2008
    ..In summary, KChIP4a, KChIP2x, and KChIP3x comprise a novel class of KChIP isoforms characterized by an unusual transmembrane domain at their N termini that modulates Kv4 channel gating and trafficking...
  6. ncbi request reprint Molecular physiology and modulation of somatodendritic A-type potassium channels
    Henry H Jerng
    Division of Neuroscience, Baylor College of Medicine, Houston, TX 77030, USA
    Mol Cell Neurosci 27:343-69. 2004
    ....
  7. pmc Modulation of Kv4.2 channel expression and gating by dipeptidyl peptidase 10 (DPP10)
    Henry H Jerng
    Division of Neuroscience, Baylor College of Medicine, Houston, Texas 77030, USA
    Biophys J 87:2380-96. 2004
    ..In summary, DPP10 is a potent modulator of Kv4 expression and biophysical properties and may be a critical component of somatodendritic ISA channels in the brain...
  8. pmc S-glutathionylation of an auxiliary subunit confers redox sensitivity to Kv4 channel inactivation
    Henry H Jerng
    Department of Neuroscience, Baylor College of Medicine, Houston, Texas, United States of America
    PLoS ONE 9:e93315. 2014
    ....