John Lynn Jefferies

Summary

Affiliation: Baylor College of Medicine
Country: USA

Publications

  1. ncbi Mechanical support in childhood heart failure
    John Lynn Jefferies
    Cardiomyopathy and Heart Failure, Cardiovascular Genetics Service, Pediatric Cardiology, Texas Children s Hospital, Baylor College of Medicine, Houston, TX, USA
    Heart Fail Clin 6:559-73, x. 2010
  2. ncbi The Twiddling Andersen
    John L Jefferies
    Section of Pediatric Cardiology, Texas Children s Hospital, Houston, Texas 77030, USA
    Tex Heart Inst J 36:349-51. 2009
  3. ncbi PTPN11 mutation associated with aortic dilation and hypertrophic cardiomyopathy in a pediatric patient with Noonan syndrome
    John L Jefferies
    Section of Pediatric Cardiology, Texas Children s Hospital, 6621 Fannin, MC 19345 C, Houston, TX 77030, USA
    Pediatr Cardiol 31:114-6. 2010
  4. ncbi Novel cardiac findings in periventricular nodular heterotopia
    John L Jefferies
    Section of Pediatric Cardiology, Texas Children s Hospital, Houston, Texas, USA
    Am J Med Genet A 152:165-8. 2010
  5. ncbi Viral endomyocardial infection is an independent predictor and potentially treatable risk factor for graft loss and coronary vasculopathy in pediatric cardiac transplant recipients
    Mousumi Moulik
    Department of Pediatrics Cardiology, University of Texas Health Sciences Center, Houston, TX, USA
    J Am Coll Cardiol 56:582-92. 2010
  6. ncbi Assessment of the Cylex ImmuKnow cell function assay in pediatric heart transplant patients
    Joseph W Rossano
    Department of Pediatrics, Baylor College of Medicine, Texas Children s Hospital, Houston, Texas, USA
    J Heart Lung Transplant 28:26-31. 2009
  7. ncbi Effect of body mass index on outcome in pediatric heart transplant patients
    Joseph W Rossano
    Department of Pediatrics, Baylor College of Medicine, Houston, Texas, USA
    J Heart Lung Transplant 26:718-23. 2007
  8. ncbi Impact of antibodies against human leukocyte antigens on long-term outcome in pediatric heart transplant patients: an analysis of the United Network for Organ Sharing database
    Joseph W Rossano
    Department of Pediatrics, Lillie Frank Abercrombie Section of Pediatric Cardiology, Baylor College of Medicine, Texas Children s Hospital, Houston, Tex 77030, USA
    J Thorac Cardiovasc Surg 140:694-9, 699.e1-2. 2010
  9. ncbi Renal effects of fenoldopam in critically ill pediatric patients: A retrospective review
    Brady S Moffett
    Texas Children s Hospital, Department of Pharmacy, Houston, TX, USA
    Pediatr Crit Care Med 9:403-6. 2008
  10. ncbi Leukocyte suppression is associated with improved clinical outcomes in children's status after orthotopic heart transplantation
    Jeffrey J Kim
    Section of Pediatric Cardiology, Department of Pediatrics, Baylor College of Medicine, Texas Children s Hospital, Houston, Texas 77030, USA
    J Heart Lung Transplant 25:195-9. 2006

Collaborators

Detail Information

Publications21

  1. ncbi Mechanical support in childhood heart failure
    John Lynn Jefferies
    Cardiomyopathy and Heart Failure, Cardiovascular Genetics Service, Pediatric Cardiology, Texas Children s Hospital, Baylor College of Medicine, Houston, TX, USA
    Heart Fail Clin 6:559-73, x. 2010
    ..Achievement of these goals requires individualized care and a familiarity with the risks and benefits of particular therapies...
  2. ncbi The Twiddling Andersen
    John L Jefferies
    Section of Pediatric Cardiology, Texas Children s Hospital, Houston, Texas 77030, USA
    Tex Heart Inst J 36:349-51. 2009
    ..Twiddler syndrome is characterized by intentional or inadvertent manipulation of implanted devices in the pacemaker pocket. We describe an unusual case of an 8-year-old girl who had both syndromes...
  3. ncbi PTPN11 mutation associated with aortic dilation and hypertrophic cardiomyopathy in a pediatric patient with Noonan syndrome
    John L Jefferies
    Section of Pediatric Cardiology, Texas Children s Hospital, 6621 Fannin, MC 19345 C, Houston, TX 77030, USA
    Pediatr Cardiol 31:114-6. 2010
    ..To our knowledge, this is the first case in which all three of these cardiovascular features have been observed in a single patient with Noonan syndrome...
  4. ncbi Novel cardiac findings in periventricular nodular heterotopia
    John L Jefferies
    Section of Pediatric Cardiology, Texas Children s Hospital, Houston, Texas, USA
    Am J Med Genet A 152:165-8. 2010
    ..These findings broaden the range of cardiac anomalies associated with filamin A mutations to include abnormality of the pulmonary valve and clefting of the mitral valve, consistent with a role for filamin A in valve leaflet development...
  5. ncbi Viral endomyocardial infection is an independent predictor and potentially treatable risk factor for graft loss and coronary vasculopathy in pediatric cardiac transplant recipients
    Mousumi Moulik
    Department of Pediatrics Cardiology, University of Texas Health Sciences Center, Houston, TX, USA
    J Am Coll Cardiol 56:582-92. 2010
    ..This study sought to evaluate the outcome and prevalence of viral endomyocardial infection after cardiac transplantation...
  6. ncbi Assessment of the Cylex ImmuKnow cell function assay in pediatric heart transplant patients
    Joseph W Rossano
    Department of Pediatrics, Baylor College of Medicine, Texas Children s Hospital, Houston, Texas, USA
    J Heart Lung Transplant 28:26-31. 2009
    ..Data on the utility of this test in pediatric heart transplant patients are very limited. This study tested the hypothesis that CICFA is a clinically useful test in this transplant population...
  7. ncbi Effect of body mass index on outcome in pediatric heart transplant patients
    Joseph W Rossano
    Department of Pediatrics, Baylor College of Medicine, Houston, Texas, USA
    J Heart Lung Transplant 26:718-23. 2007
    ..Obesity and cachexia are risk factors for adverse outcomes in adult transplant patients. However, little is known about the effects of body mass index (BMI) on outcomes in pediatric heart transplant patients...
  8. ncbi Impact of antibodies against human leukocyte antigens on long-term outcome in pediatric heart transplant patients: an analysis of the United Network for Organ Sharing database
    Joseph W Rossano
    Department of Pediatrics, Lillie Frank Abercrombie Section of Pediatric Cardiology, Baylor College of Medicine, Texas Children s Hospital, Houston, Tex 77030, USA
    J Thorac Cardiovasc Surg 140:694-9, 699.e1-2. 2010
    ..This study sought to determine the association of elevated anti-human leukocyte antibodies with long-term survival in pediatric heart transplant patients...
  9. ncbi Renal effects of fenoldopam in critically ill pediatric patients: A retrospective review
    Brady S Moffett
    Texas Children s Hospital, Department of Pharmacy, Houston, TX, USA
    Pediatr Crit Care Med 9:403-6. 2008
    ..We assessed the effects of fenoldopam on urine output and potential deleterious changes in hemodynamics or serum creatinine in children...
  10. ncbi Leukocyte suppression is associated with improved clinical outcomes in children's status after orthotopic heart transplantation
    Jeffrey J Kim
    Section of Pediatric Cardiology, Department of Pediatrics, Baylor College of Medicine, Texas Children s Hospital, Houston, Texas 77030, USA
    J Heart Lung Transplant 25:195-9. 2006
    ..Clinical outcomes in this patient population have not been well delineated...
  11. ncbi Genetic disorders with both hearing loss and cardiovascular abnormalities
    John W Belmont
    Department of Molecular and Human Genetics, and Pediatrics, Baylor College of Medicine, Houston, Tex, USA
    Adv Otorhinolaryngol 70:66-74. 2011
    ....
  12. ncbi Identification and functional characterization of NODAL rare variants in heterotaxy and isolated cardiovascular malformations
    Bhagyalaxmi Mohapatra
    Department of Pediatrics Cardiology, Baylor College of Medicine, Houston, TX 77030, USA
    Hum Mol Genet 18:861-71. 2009
    ..Taken together, these results support a role for mutations and rare deleterious variants in NODAL as a cause for sporadic human LR patterning defects...
  13. ncbi Risk factors and mode of death in isolated hypertrophic cardiomyopathy in children
    Jamie A Decker
    Lillie Frank Abercrombie Section of Pediatric Cardiology, Department of Pediatrics, Baylor College of Medicine, Houston, Texas 77030, USA
    J Am Coll Cardiol 54:250-4. 2009
    ..This study was designed to review outcomes of pediatric isolated hypertrophic cardiomyopathy (HCM) managed uniformly at a single institution and assess whether reported adult risk factors for sudden death are predictive in pediatric HCM...
  14. ncbi B-type natriuretic peptide is a sensitive screening test for acute rejection in pediatric heart transplant patients
    Joseph W Rossano
    Department of Pediatrics, Baylor College of Medicine and Texas Children s Hospital, Houston, Texas 77030, USA
    J Heart Lung Transplant 27:649-54. 2008
    ..The utility of B-type natriuretic peptide (BNP) for detecting acute rejection (AR) is unclear. The purpose of our study was to evaluate BNP as a screening test for AR in pediatric heart transplant patients...
  15. ncbi Dilated cardiomyopathy
    John Lynn Jefferies
    Pediatric Cardiology, Texas Children s Hospital, Baylor College of Medicine, Houston, TX, USA
    Lancet 375:752-62. 2010
    ..Arrhythmia therapy and prevention of sudden death continue to be mainstays of treatment. Despite progress over the past 10 years, outcomes need to be improved...
  16. ncbi Worsening renal function in children hospitalized with decompensated heart failure: evidence for a pediatric cardiorenal syndrome?
    Jack F Price
    Department of Pediatrics, Baylor College of Medicine, The Lillie Frank Abercrombie Section of Pediatric Cardiology, Texas Children s Hospital, Houston, TX, USA
    Pediatr Crit Care Med 9:279-84. 2008
    ..The purpose of this study was to determine the incidence of renal insufficiency in children hospitalized with acute decompensated heart failure and whether worsening renal function is associated with adverse cardiovascular outcome...
  17. ncbi Images in cardiovascular medicine. Rapid progression of extreme septal hypertrophic cardiomyopathy
    John L Jefferies
    Department of Cardiology, St Luke's Episcopal Hospital, Texas Heart Institute, Houston, Tex 77030, USA
    Circulation 108:e136. 2003
  18. ncbi First use of cryoplasty to treat in-stent renal artery restenosis
    John L Jefferies
    Cardiology, Texas Children s Hospital and Baylor College of Medicine, Houston, Texas 77030, USA
    Tex Heart Inst J 35:352-5. 2008
    ..We successfully treated the patient with cutting-balloon angioplasty and cryoplasty of the in-stent restenosis. To our knowledge, this is the 1st report of the use of cryotherapy to treat in-stent renal artery stenosis...
  19. ncbi Left ventricular non-compaction cardiomyopathy in children: characterisation of clinical status using tissue Doppler-derived indices of left ventricular diastolic relaxation
    Colin J McMahon
    Lillie Frank Abercrombie Section of Pediatric Cardiology, Texas Children s Hospital, Baylor College of Medicine, Houston, Texas, USA
    Heart 93:676-81. 2007
    ..It is unknown whether tissue Doppler (TD) velocities can predict adverse clinical outcomes including death and need for transplantation in children with LVNC...
  20. ncbi Administration of a large nesiritide bolus dose in a pediatric patient: case report and review of nesiritide use in pediatrics
    Brady S Moffett
    Department of Pharmacy, Texas Children s Hospital, Houston, Texas 77030, USA
    Pharmacotherapy 26:277-80. 2006
    ..Increased vigilance is always advised when administering drugs not commonly given to pediatric patients...
  21. ncbi Chest pain and diaphragmatic pacing after pacemaker implantation
    John L Jefferies
    Department of Cardiology, Texas Heart Institute at St. Luke's Episcopal Hospital, MC 1-133, P.O. Box 20345, Houston, TX 77225-0345, USA
    Tex Heart Inst J 32:106-7. 2005