Grzegorz Ira

Summary

Affiliation: Baylor College of Medicine
Country: USA

Publications

  1. doi request reprint DNA breakage drives nuclear search
    Grzegorz Ira
    Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA
    Nat Cell Biol 14:448-50. 2012
  2. pmc The Fun30 nucleosome remodeller promotes resection of DNA double-strand break ends
    Xuefeng Chen
    Department of Molecular and Human Genetics, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030, USA
    Nature 489:576-80. 2012
  3. pmc Human nuclease/helicase DNA2 alleviates replication stress by promoting DNA end resection
    Guang Peng
    Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA
    Cancer Res 72:2802-13. 2012
  4. pmc Cell cycle regulation of DNA double-strand break end resection by Cdk1-dependent Dna2 phosphorylation
    Xuefeng Chen
    Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, USA
    Nat Struct Mol Biol 18:1015-9. 2011

Collaborators

  • Xuewen Pan
  • Sang Eun Lee
  • Wei Zhang
  • Xuefeng Chen
  • Guang Peng
  • Alma Papusha
  • Jiangwu Tang
  • Yun Yong Park
  • Hui Ju Hsieh
  • Chia Dwo Chu
  • Kaifu Chen
  • Mei Ren Pan
  • Xiaotian Zhang
  • Shiaw Yih Lin
  • Ju Seog Lee
  • Isabelle Bedrosian
  • Hui Dai
  • Dandan Cui
  • Robert Yu Lin Tsai
  • Patrick Sung
  • Woo Hyun Chung
  • Zhu Zhu
  • Hengyao Niu
  • Eun Yong Shim

Detail Information

Publications4

  1. doi request reprint DNA breakage drives nuclear search
    Grzegorz Ira
    Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA
    Nat Cell Biol 14:448-50. 2012
    ..Break mobility requires resection and recombination enzymes, as well as damage-checkpoint components...
  2. pmc The Fun30 nucleosome remodeller promotes resection of DNA double-strand break ends
    Xuefeng Chen
    Department of Molecular and Human Genetics, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030, USA
    Nature 489:576-80. 2012
    ..Together these data suggest that Fun30 helps to overcome the inhibitory effect of Rad9 on DNA resection...
  3. pmc Human nuclease/helicase DNA2 alleviates replication stress by promoting DNA end resection
    Guang Peng
    Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA
    Cancer Res 72:2802-13. 2012
    ..Our findings therefore indicate that enhanced activity of DSB resection likely constitutes one mechanism whereby precancerous and cancerous cells might alleviate replication stress...
  4. pmc Cell cycle regulation of DNA double-strand break end resection by Cdk1-dependent Dna2 phosphorylation
    Xuefeng Chen
    Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, USA
    Nat Struct Mol Biol 18:1015-9. 2011
    ..Poorly recruited dna2T4A S17A S237A and dna2ΔN248 mutant proteins promote resection only in the presence of Exo1, suggesting cross-talk between Dna2- and Exo1-dependent resection pathways...