Genomes and Genes
Sarah K Highlander
Affiliation: Baylor College of Medicine
- Complete genome sequence of Enterococcus faecium strain TX16 and comparative genomic analysis of Enterococcus faecium genomesXiang Qin
Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA
BMC Microbiol 12:135. 2012..faecium strains in clinical environments. Systematic study of the molecular epidemiology and pathogenesis of E. faecium has been hindered by the lack of closed, complete E. faecium genomes that can be used as references...
- High throughput sequencing methods for microbiome profiling: application to food animal systemsSarah K Highlander
Department of Molecular Virology and Microbiology, Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030 USA
Anim Health Res Rev 13:40-53. 2012....
- Subtle genetic changes enhance virulence of methicillin resistant and sensitive Staphylococcus aureusSarah K Highlander
Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX, USA
BMC Microbiol 7:99. 2007..Epidemiological studies suggest that USA300 is more virulent than other CA-MRSA. The genetic determinants that render virulence and dominance to USA300 remain unclear...
- Genome sequence of Fusobacterium nucleatum subspecies polymorphum - a genetically tractable fusobacteriumSandor E Karpathy
Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas, United States of America Department of Microbiology and Molecular Genetics, University of Texas Medical School, Houston, Texas, United States of America
PLoS ONE 2:e659. 2007..These findings indicate that F. nucleatum subsp. polymorphum is proficient at horizontal gene transfer and that exchange with the Firmicutes, particularly the Clostridia, is common...
- The genome sequence of Mannheimia haemolytica A1: insights into virulence, natural competence, and Pasteurellaceae phylogenyJason Gioia
Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas 77030, USA
J Bacteriol 188:7257-66. 2006..haemolytica, Actinobacillus pleuropneumoniae, and Haemophilus ducreyi form a lineage distinct from other Pasteurellaceae. This observation was supported by a phylogenetic analysis using sequences of predicted housekeeping genes...
- Large scale variation in Enterococcus faecalis illustrated by the genome analysis of strain OG1RFAgathe Bourgogne
Division of Infectious Diseases, Department of Medicine, University of Texas Medical School, Houston, Texas 77030, USA
Genome Biol 9:R110. 2008..Enterococcus faecalis has emerged as a major hospital pathogen. To explore its diversity, we sequenced E. faecalis strain OG1RF, which is commonly used for molecular manipulation and virulence studies...
- Paradoxical DNA repair and peroxide resistance gene conservation in Bacillus pumilus SAFR-032Jason Gioia
Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas, USA
PLoS ONE 2:e928. 2007....
- Identification and characterization of transcriptional regulation of the Mannheimia haemolytica ferric uptake regulatorJason Gioia
Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX 77030, USA
Vet Microbiol 124:298-309. 2007..Quantitative real time PCR experiments indicated that unlike current models of Fur regulation, M. haemolytica fur transcription is unchanged by iron depletion at logarithmic phase and repressed by iron depletion at stationary phase...
- Development and Accuracy of Quantitative Real-Time Polymerase Chain Reaction Assays for Detection and Quantification of Enterotoxigenic Escherichia coli (ETEC) Heat Labile and Heat Stable Toxin Genes in Travelers' Diarrhea SamplesBonnie P Youmans
Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas Alkek Center for Metagenomics and Microbiome Research, Houston, Texas Center for Infectious Diseases, School of Public Health, University of Texas Health Science Center, Houston, Texas Department of Medicine, Baylor College of Medicine, Division of Infectious Diseases, University of Texas Medical School, St Luke s Episcopal Hospital, Houston, Texas
Am J Trop Med Hyg 90:124-32. 2014..The qPCR assays are unique in their sensitivity and ability to quantify the three toxin genes in clinical stool samples. ..
- Complete genome sequence of Rickettsia typhi and comparison with sequences of other rickettsiaeMichael P McLeod
Human Genome Sequencing Center, Baylor College of Medicine, One Baylor Plaza, Alkek N1519, Houston, TX 77030 7783, USA
J Bacteriol 186:5842-55. 2004..conorii) groups diverged. The three-way comparison allowed further in silico analysis of the SpoT split genes, leading us to propose that the stringent response system is still functional in these rickettsiae...