DIANE HICKSON BICK

Summary

Affiliation: Baylor College of Medicine
Country: USA

Publications

  1. ncbi Palmitate-mediated alterations in the fatty acid metabolism of rat neonatal cardiac myocytes
    D L Hickson-Bick
    Department of Pathology and Laboratory Medicine, University of Texas Medical School, 6431 Fannin, Houston, Texas 77030 1503, USA
    J Mol Cell Cardiol 32:511-9. 2000
  2. ncbi Palmitate-induced apoptosis in neonatal cardiomyocytes is not dependent on the generation of ROS
    Diane L M Hickson-Bick
    Department of Pathology and Laboratory Medicine, University of Texas Medical School, Houston, Texas 77030, USA
    Am J Physiol Heart Circ Physiol 282:H656-64. 2002
  3. ncbi The response of neonatal rat ventricular myocytes to lipopolysaccharide-induced stress
    Diane L M Hickson-Bick
    Department of Pathology and Laboratory Medicine, University of Texas Medical School, Houston, TX 77030, USA
    Shock 25:546-52. 2006
  4. ncbi Stimulation of mitochondrial biogenesis and autophagy by lipopolysaccharide in the neonatal rat cardiomyocyte protects against programmed cell death
    Diane L M Hickson-Bick
    Department of Pathology and Laboratory Medicine, University of Texas Medical School, Houston, TX 77030, USA
    J Mol Cell Cardiol 44:411-8. 2008
  5. ncbi Circadian rhythms in myocardial metabolism and contractile function: influence of workload and oleate
    David J Durgan
    United States Department of Agriculture Agricultural Research Service Children s Nutrition Research Center, Department of Pediatrics, Houston, Texas, USA
    Am J Physiol Heart Circ Physiol 293:H2385-93. 2007

Research Grants

  1. FATTY ACID METABOLISM IN CARDIAC ISCHEMIA
    DIANE HICKSON BICK; Fiscal Year: 2002
  2. The role of cardiolipin apoptosis
    DIANE HICKSON BICK; Fiscal Year: 2007

Collaborators

  • Jason R B Dyck
  • Margaret P Chandler
  • MARTIN ELLIOT YOUNG
  • Diane L M Hickson-Bick
  • L Maximilian Buja
  • David J Durgan
  • Chad Jones
  • D L Hickson-Bick
  • Michael W S Moore
  • Anu Egbejimi
  • Vijayalakshmi Nannegari
  • William C Heird
  • DIANE L HICKSON-BICK
  • Chad A Shaw
  • Ngan P Ha
  • Molly S Bray
  • Oluwaseun Egbejimi
  • Uchenna Mbawuike
  • Anna Fields
  • Jeanie B McMillin
  • Genevieve C Sparagna
  • L M Buja
  • J B McMillin

Detail Information

Publications5

  1. ncbi Palmitate-mediated alterations in the fatty acid metabolism of rat neonatal cardiac myocytes
    D L Hickson-Bick
    Department of Pathology and Laboratory Medicine, University of Texas Medical School, 6431 Fannin, Houston, Texas 77030 1503, USA
    J Mol Cell Cardiol 32:511-9. 2000
    ..Our data suggest that decreased palmitate oxidation in cardiac myocytes in culture may signal the initiation of programmed cell death and ceramide elevation previously documented in ischemic, reperfused hearts...
  2. ncbi Palmitate-induced apoptosis in neonatal cardiomyocytes is not dependent on the generation of ROS
    Diane L M Hickson-Bick
    Department of Pathology and Laboratory Medicine, University of Texas Medical School, Houston, Texas 77030, USA
    Am J Physiol Heart Circ Physiol 282:H656-64. 2002
    ..No evidence was found for an increase in oxidative protein modification in palmitate-treated cells. Our results lead us to conclude that oxidative stress does not play a role in palmitate-induced apoptosis...
  3. ncbi The response of neonatal rat ventricular myocytes to lipopolysaccharide-induced stress
    Diane L M Hickson-Bick
    Department of Pathology and Laboratory Medicine, University of Texas Medical School, Houston, TX 77030, USA
    Shock 25:546-52. 2006
    ..Metabolic products of arachidonic acid metabolized by the cyclooxygenase pathway can be potentially apoptotic or antiapoptotic. The balance of these products within these cells may define the cellular response to LPS exposure...
  4. ncbi Stimulation of mitochondrial biogenesis and autophagy by lipopolysaccharide in the neonatal rat cardiomyocyte protects against programmed cell death
    Diane L M Hickson-Bick
    Department of Pathology and Laboratory Medicine, University of Texas Medical School, Houston, TX 77030, USA
    J Mol Cell Cardiol 44:411-8. 2008
    ..Viable cells replace dysfunctional mitochondria by mitochondrial biogenesis and the extent of the damage limited by the rapid removal of damaged organelles by the stimulation of autophagy...
  5. ncbi Circadian rhythms in myocardial metabolism and contractile function: influence of workload and oleate
    David J Durgan
    United States Department of Agriculture Agricultural Research Service Children s Nutrition Research Center, Department of Pediatrics, Houston, Texas, USA
    Am J Physiol Heart Circ Physiol 293:H2385-93. 2007
    ..In conclusion, these studies expose marked circadian rhythmicities in myocardial oxidative and nonoxidative metabolism as well as responsiveness of the rat heart to changes in workload and fatty acid availability...

Research Grants5

  1. FATTY ACID METABOLISM IN CARDIAC ISCHEMIA
    DIANE HICKSON BICK; Fiscal Year: 2002
    ..Location of a malonyl-CoA compartment that is inaccessible to CPT-I will shed light on the inconsistency between the high malonyl CoA content in heart and reliance on beta-oxidation. ..
  2. The role of cardiolipin apoptosis
    DIANE HICKSON BICK; Fiscal Year: 2007
    ..The role of these modified phospholipids in cyt c release will be determined. We will answer the question "is the loss of cyt c preceded by deacylation of CL?" ..