Research Topics
Genomes and Genes
| John HicksSummaryAffiliation: Baylor College of Medicine Country: USA Publications
| Collaborators
|
Detail Information
Publications
The spectrum of pediatric fibroblastic and myofibroblastic tumorsJohn Hicks
Texas Children s Cancer Center Cytogenetics Laboratory, Texas Children s Hospital and Baylor College of Medicine, Department of Pathology, Houston, Texas 77030 2313, USA
Ultrastruct Pathol 28:265-81. 2004....
Review of autoimmune (lupus-like) glomerulonephritis in murine modelsJohn Hicks
Department of Pathology, Texas Children s Hospital and Baylor College of Medicine, Houston, Texas 77030 2313, USA
Ultrastruct Pathol 30:345-59. 2006....
Fluoride-releasing resin bonding of amalgam restorations in primary teeth: in vitro secondary caries effectJohn Hicks
Department of Pathology, Texas Children s Hospital, Baylor College of Medicine, Houston, TX 77030 2399, USA
Am J Dent 15:361-4. 2002..To evaluate the effects of a fluoride-releasing resin designed for amalgam bonding on secondary caries formation in primary teeth restored with amalgams...
Fluoride-releasing restorative materials and secondary cariesJohn Hicks
Department of Pathology, Texas Children s Hospital, Houston 77030 2399, USA
J Calif Dent Assoc 31:229-45. 2003....
Restoration-enamel interface with argon laser and visible light polymerization of compomer and composite resin restorations: a polarized light and scanning electron microscopic in vitro studyJ Hicks
Department of Pathology, Texas Children s Hospital, Baylor College of Medicine, Houston, TX, USA
J Clin Pediatr Dent 27:353-8. 2003..Such restoration-enamel interfaces may provide a certain degree of resistance against secondary caries formation, and this may be enhanced by the caries protective effect of argon laser irradiation...
Biologic, cytogenetic, and molecular factors in mesothelial proliferationsJohn Hicks
Department of Pathology, Texas Children s Hospital and Baylor College of Medicine, Houston, Texas 77030 2313, USA
Ultrastruct Pathol 30:19-30. 2006..The future holds great promise in identifying mesothelioma gene expression profiles (genomics, gene microarrays) and proteins (proteomics) that may produce the key to dealing with this dismal and devastating neoplasm...
Biological factors in dental caries: role of saliva and dental plaque in the dynamic process of demineralization and remineralization (part 1)John Hicks
Department of Pathology, Texas Children s Hospital, Baylor College of Medicine, Houston Tx 77030 2313, USA
J Clin Pediatr Dent 28:47-52. 2003....
Primary tooth enamel surface topography with in vitro argon laser irradiation alone and combined fluoride and argon laser treatment: scanning electon microscopic studyJ Hicks
Department of Pathology, Texas Children s Hospital and Baylor College of Medicine, Houston, Tex, USA
Pediatr Dent 25:491-6. 2003....
Genome, proteome, and metabolome: where are we going?John Hicks
Department of Pathology, Texas Children s Hospital and Baylor College of Medicine, Houston, Texas 77030, USA
Ultrastruct Pathol 27:289-94. 2003..The role of the pathologist in expression profiling for diseases and tumorigenesis is of considerable importance in providing diagnostic information and predicting outcome based on pathobiologic features of diseases and tumors...
In vivo caries formation in enamel following argon laser irradiation and combined fluoride and argon laser treatment: a clinical pilot studyJohn Hicks
Department of Pathology, Texas Children s Hospital, Baylor College of Medicine, Houston, Texas 77030, USA
Quintessence Int 35:15-20. 2004..This in vivo pilot study investigated the role of argon laser irradiation and combined fluoride and argon laser treatment in accelerated natural caries development in sound enamel surfaces beneath plaque-retentive orthodontic bands...
Biological factors in dental caries enamel structure and the caries process in the dynamic process of demineralization and remineralization (part 2)John Hicks
Department of Pathology, Texas Children s Hospital, Baylor College of Medicine, Houston, TX 77030 2313, USA
J Clin Pediatr Dent 28:119-24. 2004..The chemical reactions that occur during acidic conditions when tooth mineral dissolves (critical pH) are determined by the supersaturation of calcium and phosphate within plaque and saliva, as well as if fluoride is present...
Biological factors in dental caries: role of remineralization and fluoride in the dynamic process of demineralization and remineralization (part 3)John Hicks
Department of Pathology, Texas Children s Hospital, Baylor College of Medicine, Houston 77030 2313, USA
J Clin Pediatr Dent 28:203-14. 2004..The role of systemic fluorides appears to be limited and primarily has a topical effect...
Langerhans cell histiocytosis: current insights in a molecular age with emphasis on clinical oral and maxillofacial pathology practiceJohn Hicks
Surgical and Ultrastructural Pathology, Texas Children s Hospital, Houston 77030 2313, USA
Oral Surg Oral Med Oral Pathol Oral Radiol Endod 100:S42-66. 2005..Discovery of biologic, cytogenetic, and molecular abnormalities in LCH have already affected treatment by providing novel therapeutic targets...
The spectrum of pediatric tumors in infancy, childhood, and adolescence: a comprehensive review with emphasis on special techniques in diagnosisJohn Hicks
Department of Pathology, Texas Children s Hospital and Baylor College of Medicine, Houston, Texas 77030, USA
Ultrastruct Pathol 29:175-202. 2005..This review provides updated guidelines with respect to the application of these special techniques in this rapidly evolving diagnostic arena...
USCAP Specialty Conference, case 2: chondroblastic osteosarcoma with features resembling chondromyxoid fibromaJohn Hicks
Department of Pathology, Texas Children's Hospital and Baylor College of Medicine, 6621 Fannin Street, Houston, TX 77030-2313, USA
Pediatr Dev Pathol 8:67-73. 2005
Differentiating undifferentiated and poorly differentiated sarcomas--a multidisciplinary approach: the 2007 Society for Ultrastructural Pathology companion meetingJohn Hicks
Texas Children's Hospital and Baylor College of Medicine, Houston, Texas 77030, USA
Ultrastruct Pathol 32:29-30. 2008
Lipoblastoma and lipoblastomatosis in infancy and childhood: histopathologic, ultrastructural, and cytogenetic featuresJ Hicks
Department of Pathology, Texas Children s Hospital and Baylor College of Medicine, Houston 77030 2399, USA
Ultrastruct Pathol 25:321-33. 2001..Although asymptomatic, lipoblastomas may cause dysfunction of other organ systems due to mass effect. Complete surgical excision with at least 2 years of follow-up is the preferred therapy...
Dental caries in HIV-infected children: a longitudinal studyM J Hicks
Department of Pathology, Baylor College of Medicine, USA
Pediatr Dent 22:359-64. 2000....
Fluoride-releasing restorative materials and secondary cariesJohn Hicks
Department of Pathology, Texas Children s Hospital, Baylor College of Medicine, Houston, TX, USA
Dent Clin North Am 46:247-76, vi. 2002....
Resin-modified glass-ionomer restorations and in vitro secondary caries formation in coronal enamelM J Hicks
Department of Pathology, Texas Children s Hospital, USA
Quintessence Int 31:570-8. 2000..The purpose of this laboratory study was to compare the effects of a resin-modified glass ionomer and a resin composite restorative material on secondary caries formation in coronal enamel...
Tracheomalacia in a neonate with kniest dysplasia: histopathologic and ultrastructural featuresJ Hicks
Department of Pathology, Texas Children s Hospital, Houston 77030 2399, USA
Ultrastruct Pathol 25:79-83. 2001..Both the quantity and quality of type II collagen modulates the phenotypic expression of type II collagenopathies...
Compomer materials and secondary caries formationJ Hicks
Department of Pathology, Texas Children s Hospital and Baylor College of Medicine, Houston 77030 2399, USA
Am J Dent 13:231-4. 2000..To evaluate the role of compomers in secondary caries formation in vitro...
Occlusal caries formation in vitro: comparison of resin-modified glass ionomer with fluoride-releasing sealantM J Hicks
Department of Pathology, Texas Children s Hospital and Baylor College of Medicine, 6621 Fannin Street, Houston, TX 77030 2399, USA
J Clin Pediatr Dent 24:309-14. 2000....
Uncombable hair (cheveux incoiffables, pili trianguli et canaliculi) syndrome: brief review and role of scanning electron microscopy in diagnosisJ Hicks
Department of Pathology, Texas Children s Hospital, Baylor College of Medicine, Houston 77030 2399, USA
Ultrastruct Pathol 25:99-103. 2001..Scanning electron microscopy of hair samples provides definitive evidence for diagnosis of clinically suspected uncombable hair syndrome and eliminates other hair abnormalities from the differential diagnosis...
Plasma proteome predicts chemotherapy response in osteosarcoma patientsYiting Li
Texas Children s Cancer Center, Texas Children s Hospital, and Department of Pediatrics, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA
Oncol Rep 25:303-14. 2011....
Role of remineralizing fluid in in vitro enamel caries formation and progressionJohn Hicks
Department of Pathology, Texas Children s Hospital and Baylor College of Medicine, Houston, TX 77030, USA
Quintessence Int 38:313-9. 2007..To evaluate a remineralizing fluid for its influence on in vitro caries formation and progression...
Fluoride-releasing orthodontic adhesives and topical fluoride effect on enamel caries formation: an in vitro studyKendra Covington Pratt
Department of Pathology, MC1 2261, Texas Children s Hospital, 6621 Fannin St, Houston, TX 77030 2313, USA
Am J Dent 23:179-84. 2010..To examine in vitro orthodontic bonding sealants combined with daily fluoride (NaF) rinse on caries-like lesion depths...
Identification of a plasma proteomic signature to distinguish pediatric osteosarcoma from benign osteochondromaYiting Li
Texas Children's Cancer Center, Texas Children's Hospital, Baylor College of Medicine, Houston, TX, USA
Proteomics 6:3426-35. 2006..The classifier based on this plasma proteomic signature may be useful to differentiate malignant bone cancer from benign bone tumors and for early detection of OS in high-risk individuals...
Elevated expression of CXC chemokines in pediatric osteosarcoma patientsYiting Li
Texas Children s Cancer Center, Texas Children s Hospital, Houston, Texas Department of Pediatrics, Baylor College of Medicine, Houston, Texas, USA
Cancer 117:207-17. 2011..Despite the advent of chemotherapy, the survival of osteosarcoma patients has not been significantly improved recently. Chemokines are a group of signaling molecules that have been implicated in tumorigenesis and metastasis...
Expression profiles of osteosarcoma that can predict response to chemotherapyTsz-Kwong Man
Department of Pediatrics, Texas Children's Cancer Center, Houston, Texas, USA
Cancer Res 65:8142-50. 2005..Many of the predictor genes are implicated in bone development, drug resistance, and tumorigenesis...
In vitro enamel caries formation and orthodontic bonding agentsKarin Cain
Department of Pathology, Texas Children's Hospital, Baylor College of Medicine, Houston 77030-2313, USA
Am J Dent 19:187-92. 2006..Caries-like lesions were only present in the exposed enamel windows adjacent to the orthodontic bonding agents...
Mdm2 deficiency suppresses MYCN-Driven neuroblastoma tumorigenesis in vivoZaowen Chen
Texas Children s Cancer Center and Center for Cell and Gene Therapy, Baylor College of Medicine, Houston, TX 77030, USA
Neoplasia 11:753-62. 2009..In summary, we provided evidence for a crucial role for direct inhibition of p53 by MDM2 and suppression of the p19(ARF)/p53 axis in neuroblastoma tumorigenesis, supporting the development of therapies targeting these pathways...
Identification and gene expression profiling of tumor-initiating cells isolated from human osteosarcoma cell lines in an orthotopic mouse modelNino Rainusso
Texas Children s Cancer Center and Hematology Service, Houston, USA
Cancer Biol Ther 12:278-87. 2011..PKH26 labeling represents a valuable tool to identify OS TICs and gene expression analysis of this tumor cell compartment may identify potential therapeutic targets...
E-selectin ligand-1 regulates growth plate homeostasis in mice by inhibiting the intracellular processing and secretion of mature TGF-betaTao Yang
Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA
J Clin Invest 120:2474-85. 2010..This study identifies what we believe to be a novel intracellular mechanism for regulating TGF-beta during skeletal development and homeostasis...
Visceral clear cell sarcoma of soft tissue with confirmation by EWS-ATF1 fusion detectionLaura Granville
Department of Pathology, Texas Children's Hospital, Baylor, College of Medicine, Houston, Texas 77030-2313, USA
Ultrastruct Pathol 30:111-8. 2006....
Kinetic cavity preparation effects on secondary caries formation around resin restorations: a polarized light microscopic in vitro evaluationM J Hicks
Department of Pathology, Baylor College of Medicine and Texas Children s Hospital, TX, USA
ASDC J Dent Child 68:115-21, 80, 142. 2001..Resin restorations placed in cavities prepared by air abrasion (KCP) and conventional handpiece techniques provided similar degrees of protection against a secondary caries-like challenge...
Cell cycle regulator gene CDC5L, a potential target for 6p12-p21 amplicon in osteosarcomaXin Yan Lu
Texas Children s Cancer Center, Baylor College of Medicine, 6621 Fannin Street, MC 3 3320, Houston, TX 77030, USA
Mol Cancer Res 6:937-46. 2008..These results indicate that CDC5L, a cell cycle regulator important for the G2-M transition, is the most likely candidate oncogene for the 6p12-p21 amplicon found in osteosarcoma...
Juvenile xanthogranuloma of the oral cavity in children: a clinicopathologic studyCatherine Flaitz
Division of Oral and Maxillofacial Surgery and Pathology, University of Texas Houston Health Science Center, Dental Branch, Houston, Tex 77030, USA
Oral Surg Oral Med Oral Pathol Oral Radiol Endod 94:345-52. 2002..This clinicopathologic study describes the histopathologic, immunocytochemical, and electron microscopic features of oral juvenile xanthogranuloma (JXG) in children...
Ultrastructure of the Ewing's sarcoma family of tumorsChae-Hong Suh
Department of Pathology, University of Texas M. D. Anderson Cancer Center, Houston 77030, USA
Ultrastruct Pathol 26:67-76. 2002....
Caries formation in vitro around a fluoride-releasing pit and fissure sealant in primary teethM J Hicks
Department of Pathology, Texas Children s Hospital, Houston, Texas, USA
ASDC J Dent Child 65:161-8. 1998....
Liposarcoma in children and young adults: a multi-institutional experienceWinston W Huh
Division of Pediatrics, University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA
Pediatr Blood Cancer 57:1142-6. 2011..There are limited data regarding the differences in clinical presentation and outcome of liposarcomas between adult and pediatric patients. The role of adjuvant radiotherapy in the treatment of childhood liposarcoma is unclear...
Renal diseases associated with hematuria in children and adolescents: a brief tutorialJohn Hicks
Department of Pathology, Texas Children s Hospital and Baylor College of Medicine, Houston, Texas 77030, USA
Ultrastruct Pathol 36:1-18. 2012....
CXCR4 expression in neuroblastoma primary tumors is associated with clinical presentation of bone and bone marrow metastasesHeidi V Russell
Texas Children s Cancer Center and Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA
J Pediatr Surg 39:1506-11. 2004..The goal of this study was to investigate whether the degree of expression of CXCR4 on cells from neuroblastoma primary tumors was related to the pattern of metastatic involvement...
Progressive transformation of germinal centers: review of histopathologic and clinical featuresJohn Hicks
Department of Pathology, Texas Children s Hospital and Baylor College of Medicine, MC1 2261, 6621 Fannin Street, Houston, TX77030 2399, USA
Int J Pediatr Otorhinolaryngol 65:195-202. 2002..PTGC may be mistaken for focal nodular lymphocyte predominant Hodgkin's Disease (NLPHD)...
Metastatic squamous cell carcinoma of the oropharynx in a child with a mutation in the Connexin 26 geneSurya Rednam
Department of Pediatrics, Texas Children s Hospital, Baylor College of Medicine, Houston, TX, USA
J Pediatr Hematol Oncol 33:387-9. 2011..This association emphasizes the need to consider Connexin 26 gene mutations in children who develop oral squamous cell carcinoma and to monitor for oral squamous cell carcinoma in children with Connexin 26 gene mutations...
A comparative, long-term assessment of four soft tissue substitutesPatrick D Cole
Division of Plastic Surgery, Baylor College of Medicine, Houston, Texas, USA
Aesthet Surg J 31:674-81. 2011..DuraMatrix (bovine tendon matrix; Stryker Corp.) is also promising, demonstrating desirable properties not only as a dural substitute but also for soft tissue replacement...
Oral manifestations of pediatric vertical HIV infectionC A Kozinetz
Department of Pediatrics, Baylor College of Medicine, Houston, Texas, USA
AIDS Patient Care STDS 14:89-94. 2000..Oral manifestations are significant clinical outcomes in pediatric vertical HIV infection, particularly for children diagnosed previously with an oral manifestation...
Surface topography and enamel-resin interface of pit and fissure sealants following visible light and argon laser polymerization: an in vitro studyM J Hicks
Department of Pathology, Texas Children s Hospital, Baylor College of Medicine, USA
ASDC J Dent Child 67:169-75, 160. 2000..The benefit of argon laser polymerization, fluoride release and mechanical protection of sealant material may provide improved caries resistance in sealed pits and fissures and adjacent nonsealed enamel surfaces...
Sinonasal teratocarcinosarcoma in an adolescent maleNeeraj Agrawal
Department of Radiation Oncology, The Methodist Hospital, Houston, TX 77030, USA
J Pediatr Hematol Oncol 34:e304-7. 2012..He presented with epistaxis, nasal obstruction, and frontal headaches and was treated with resection and postoperative chemoradiation. He is currently doing well without evidence of recurrence 45 months after therapy...
Abdominal undifferentiated small round cell tumor with unique translocation (X;19)(q13;q13.3)Jason T Yustein
Department of Pediatrics, Texas Children s Cancer Center, Baylor College of Medicine, Houston, Texas, USA
Pediatr Blood Cancer 54:1041-4. 2010..3), which has not been reported in small round cell tumors of childhood or adults. The final diagnosis rendered was an undifferentiated small round cell tumor of uncertain cell of origin...
MYCN-directed centrosome amplification requires MDM2-mediated suppression of p53 activity in neuroblastoma cellsAndrew D Slack
Center for Cell and Gene Therapy, Texas Children s Cancer Center, Baylor College of Medicine, Houston, Texas 77030, USA
Cancer Res 67:2448-55. 2007..These data support the hypothesis that elevated MDM2 levels contribute to MYCN-induced genomic instability through altered regulation of centrosome replication in neuroblastoma...
Generalized metabolic bone disease in Neurofibromatosis type INicola Brunetti-Pierri
Department of Molecular and Human Genetics, Baylor College of Medicine, One Baylor Plaza, Room 635E, Houston, TX 77030, USA
Mol Genet Metab 94:105-11. 2008..Early identification of patients with osteoporosis may permit more timely and aggressive treatments to prevent the likely substantial morbidity associated with increased fracture risk later in life...
CRTAP is required for prolyl 3- hydroxylation and mutations cause recessive osteogenesis imperfectaRoy Morello
Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA
Cell 127:291-304. 2006..In humans, CRTAP mutations are associated with the clinical spectrum of recessive osteogenesis imperfecta, including the type II and VII forms. Hence, dysregulation of prolyl 3-hydroxylation is a mechanism for connective tissue disease...
Local cryoglobulin deposition in primary central nervous system lymphomaPaisit Paueksakon
Department of Neurosurgery, Baylor College of Medicine and Texas Children's Hospital, Houston, 77030, USA
Hum Pathol 34:720-4. 2003..This report demonstrates localized cryoglobulin deposition within the tumor bed in an immunocompetent patient with PCNSL...
An unusual presentation of mastocytosis: unilateral swelling of the vulvaJoydip Roy
Department of Pediatrics, Endocrinology, Dermatology, and Pathology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas, USA
Pediatr Dermatol 22:554-7. 2005..In the appropriate setting, mastocytosis should be included in the differential diagnosis of labium majus swelling...
Glycogen storage diseases: a brief review and update on clinical features, genetic abnormalities, pathologic features, and treatmentJohn Hicks
Department of Pathology, Texas Children s Hospital, Baylor College of Medicine, Houston, Texas 77030, USA
Ultrastruct Pathol 35:183-96. 2011..The paper provides a brief review and update of glycogen storage diseases, with respect to clinical features, genetic abnormalities, pathologic features, and treatment...
Imaging accuracy and incidence of Wilms' and non-Wilms' renal tumors in childrenDoug Miniati
Division of Pediatric Surgery, Michael E DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX, USA
J Pediatr Surg 43:1301-7. 2008..The purpose of this study is to determine the actual incidence, age distribution, and preoperative imaging accuracy of non-Wilms' tumors (nWT) in children with renal masses...
Retroperitoneal lipoblastoma: a discussion of current managementDaniela Burchhardt
Texas Children s Hospital, Department of Pediatric Surgery, Baylor College of Medicine, Houston, TX, USA
J Pediatr Surg 47:e51-4. 2012..We present one such case of a large, retroperitoneal lipoblastoma and discuss the management of this uncommon entity...
A change in hair color and texture in a healthy girlKatherine A Bell
Baylor College of Medicine, Houston, TX, USA
Arch Dermatol 138:689-94. 2002
Assessing the long-term retention and permanency of acellular cross-linked porcine dermal collagen as a soft-tissue substitutePat Kelley
Division of Plastic and Reconstructive Surgery, The Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, Texas, USA
Plast Reconstr Surg 116:1780-4. 2005..The porcine dermis would appear from these results to be better suited for situations that require strength and permanence of the implant...
Frequent amplification and rearrangement of chromosomal bands 6p12-p21 and 17p11.2 in osteosarcomaChing C Lau
Department of Pediatrics, Texas Children s Cancer Center, Baylor College of Medicine, Houston, Texas 77030, USA
Genes Chromosomes Cancer 39:11-21. 2004....
Enamel caries formation and lesion progression with a fluoride dentifrice and a calcium-phosphate containing fluoride dentifrice: a polarized light microscopic studyM J Hicks
Department of Pediatric Dentistry, University of Texas Houston Health Science Center Dental Branch, Houston, USA
ASDC J Dent Child 67:21-8, 8. 2000..05, ANOVA, DMR). Addition of bioavailable calcium and phosphate ions to a fluoride dentifrice may improve the ability of enamel to resist caries initiation and subsequent lesion progression...
Plasmablastic lymphoma: an HIV-associated entity with primary oral manifestationsC M Flaitz
Department of Stomatology, University of Texas Houston Health Science Center, Dental Branch, 6516 John Freeman Avenue, Houston, TX 77030, USA
Oral Oncol 38:96-102. 2002..The same tumor was negative for HHV-8 by PCR. Recognition of plasmablastic lymphoma is important, because it represents an HIV-associated malignancy that predominantly involves the oral cavity, may mimic KS and has a poor prognosis...
The "ultra" years and many more to come: a glimpse into the futureJohn Hicks
Ultrastruct Pathol 27:287-8. 2003
The spectrum of fibroblastic tumors: current insights--Society for Ultrastructural Pathology companion meeting at the United States and Canadian Academy of Pathology annual session in Vancouver, March 2004John Hicks
Ultrastruct Pathol 28:263-4. 2004
Disseminated Acanthamoeba infection in a human immunodeficiency virus-infected infantHeidi Schwarzwald
Department of Pediatrics, Baylor College of Medicine and Texas Children s Hospital, Houston, 77030, USA
Pediatr Infect Dis J 22:197-9. 2003..We present the first case of disseminated Acanthamoeba infection in an HIV-infected infant. The infant survived 2 years with treatment with several agents having anti-Acanthamoeba activity in vitro...
T-cell epitope of alpha3 chain of type IV collagen induces severe glomerulonephritisJean Wu
Department of Basic Science, Dental Branch, University of Texas Health Science Center at Houston, Houston, Texas 77030, USA
Kidney Int 64:1292-301. 2003....
CD4(+) T cells specific to a glomerular basement membrane antigen mediate glomerulonephritisJean Wu
Department of Basic Science, Dental Branch, University of Texas Houston Health Science Center, Houston, Texas 77030, USA
J Clin Invest 109:517-24. 2002..Many of the T cells were located in the Bowman's space and had a flattened shape, suggesting that the primary target for the T cells was in or adjacent to the Bowman's capsule...
Anti-CD52 antibody, alemtuzumab, binds to Langerhans cells in Langerhans cell histiocytosisMichael B Jordan
Department of Pediatrics, University of Colorado Health Sciences Center and The Children's Hospital, Denver, Colorado, USA
Pediatr Blood Cancer 44:251-4. 2005..Such therapy is particularly needed for patients with refractory, high-risk disease. Further investigation of the possible clinical use of this antibody in these patients is warranted...
From benchtop to dental practice: a century of discovery at The University of Texas Dental Branch at HoustonCatherine M Flaitz
Oral and Maxillofacial Pathology and Pediatric Dentistry, The University of Texas Dental Branch at Houston, USA
Tex Dent J 122:258-67. 2005
Extent of iron pick-up in deforoxamine-coupled polyurethane materials for therapy of chronic woundsJennifer E Taylor
Department of Materials Science, University of Cambridge, Pembroke Street, Cambridge CB2 3QZ, UK
Biomaterials 26:6024-33. 2005..These studies have shown the activity of iron with respect to ionic state in DFO-activated PNS for potential using as dressing for chronic wounds...
Rapid development of glomerular injury and renal failure in mice lacking p53R2David R Powell
Lexicon Genetics Incorporated, The Woodlands, TX 77381, USA
Pediatr Nephrol 20:432-40. 2005..These findings suggest that lack of p53R2, the protein encoded by Rrm2b, has early and relatively selective detrimental effects on the kidney glomerulus that lead to rapid death from progressive renal failure...
