Affiliation: Baylor College of Medicine
- Functional diversity, conservation, and convergence in the evolution of the alpha-, beta-, and gamma-carbonic anhydrase gene familiesD Hewett-Emmett
Human Genetics Center, University of Texas Health Science Center at Houston 77225, USA
Mol Phylogenet Evol 5:50-77. 1996..The plant Arabidopsis has homologues of all three families...
- Evolution of paired domains: isolation and sequencing of jellyfish and hydra Pax genes related to Pax-5 and Pax-6H Sun
Human Genetics Center, School of Public Health, University of Texas, P O Box 20334, Houston, TX 77225, USA
Proc Natl Acad Sci U S A 94:5156-61. 1997..From this analysis and the gene structure, we propose that modern Pax-4/6 and Pax-2/5/8 genes evolved from an ancestral gene similar to cnidarian Pax-B, having both the homeodomain and the octapeptide...
- High polymorphism at the human melanocortin 1 receptor locusB K Rana
Human Genetics Center, School of Public Health and Graduate School of Biomedical Sciences, University of Texas, Houston, Texas 77030, USA
Genetics 151:1547-57. 1999..In addition, the nucleotide diversity at the MC1R locus is shown to be several times higher than the average nucleotide diversity in human populations, possibly due to diversifying selection...
- Genomic characterization of human DSPG3M Deere
Graduate School of Biomedical Sciences, Program in Human and Molecular Genetics, University of Texas, Health Science Center, Houston, Texas 77030, USA
Genome Res 9:449-56. 1999..Hence, it appears that the majority of the introns in the SLRP genes were inserted after the differentiation of the SLRP genes from an ancestral gene that was most likely composed of 2-3 exons...
- Evolutionarily conserved, "acatalytic" carbonic anhydrase-related protein XI contains a sequence motif present in the neuropeptide sauvagine: the human CA-RP XI gene (CA11) is embedded between the secretor gene cluster and the DBP gene at 19q13.D A Lovejoy
The Clayton Foundation Laboratories for Peptide Biology, The Salk Institute, 10010 North Torrey Pines Road, La Jolla, California, 92037, USA
Genomics 54:484-93. 1998....
- Frequent gene conversion between human red and green opsin genesZ Zhao
J Mol Evol 46:494-6. 1998..In conclusion, gene conversion has occurred frequently between human red and green opsin genes, but exons 2, 3, 4, and 5 have been maintained distinct between the two genes by natural selection...
- Mitochondrial carbonic anhydrase CA VB: differences in tissue distribution and pattern of evolution from those of CA VA suggest distinct physiological rolesG N Shah
Edward A Doisy Department of Biochemistry and Molecular Biology, Department of Pediatrics, St Louis University School of Medicine, St Louis, MO 63104, USA
Proc Natl Acad Sci U S A 97:1677-82. 2000..Both the differences in tissue distribution and the much greater evolutionary constraints on CA VB sequences suggest that CA VB and CA VA have evolved to assume different physiological roles...
- Organization of the mouse and human carbonic anhydrase II genesP J Venta
Ann N Y Acad Sci 429:309-23. 1984
- Carbonic anhydrase II deficiency in 12 families with the autosomal recessive syndrome of osteopetrosis with renal tubular acidosis and cerebral calcificationW S Sly
N Engl J Med 313:139-45. 1985....
- Nucleotide sequence of human liver carbonic anhydrase II cDNAJ C Montgomery
Nucleic Acids Res 15:4687. 1987
- Comparison of the 5' regions of human and mouse carbonic anhydrase II genes and identification of possible regulatory elementsP J Venta
Biochim Biophys Acta 826:195-201. 1985..In addition, several CCGCCC or GGGCGG sequences which may be important for transcriptional efficiency are found in the 5' flanking regions of the human and mouse genes...
- Structure and exon to protein domain relationships of the mouse carbonic anhydrase II geneP J Venta
J Biol Chem 260:12130-5. 1985..During this study, the possible basis for the two electrophoretic types, CA IIa and CA IIb, of inbred mouse strains was detected as a Gln/His interchange at position 38...