Sandra L Grimm

Summary

Affiliation: Baylor College of Medicine
Country: USA

Publications

  1. pmc Keratin 6 is not essential for mammary gland development
    Sandra L Grimm
    Department of Molecular and Cellular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA
    Breast Cancer Res 8:R29. 2006
  2. pmc Progesterone receptor and Stat5 signaling cross talk through RANKL in mammary epithelial cells
    Alison E Obr
    PhD, Department of Molecular and Cellular Biology, Baylor College of Medicine, BCM Box 130, One Baylor Plaza, Houston, Texas 77030
    Mol Endocrinol 27:1808-24. 2013
  3. ncbi request reprint Cell cycle defects contribute to a block in hormone-induced mammary gland proliferation in CCAAT/enhancer-binding protein (C/EBPbeta)-null mice
    Sandra L Grimm
    Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas 77030, USA
    J Biol Chem 280:36301-9. 2005
  4. ncbi request reprint The role of C/EBPbeta in mammary gland development and breast cancer
    Sandra L Grimm
    Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas 77030, USA
    J Mammary Gland Biol Neoplasia 8:191-204. 2003
  5. pmc Progesterone receptor directly inhibits β-casein gene transcription in mammary epithelial cells through promoting promoter and enhancer repressive chromatin modifications
    Adam C Buser
    Baylor College of Medicine, Department of Molecular and Cellular Biology, Houston, Texas 77030, USA
    Mol Endocrinol 25:955-68. 2011
  6. pmc Stop! In the name of transforming growth factor-beta: keeping estrogen receptor-alpha-positive mammary epithelial cells from proliferating
    Sandra L Grimm
    Department of Molecular and Cellular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA
    Breast Cancer Res 8:106. 2006
  7. ncbi request reprint Disruption of steroid and prolactin receptor patterning in the mammary gland correlates with a block in lobuloalveolar development
    Sandra L Grimm
    Department of Molecular and Cellular Biology, Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA
    Mol Endocrinol 16:2675-91. 2002
  8. ncbi request reprint Jak2 is an essential tyrosine kinase involved in pregnancy-mediated development of mammary secretory epithelium
    Jonathan M Shillingford
    Laboratory of Genetics and Physiology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
    Mol Endocrinol 16:563-70. 2002

Collaborators

Detail Information

Publications8

  1. pmc Keratin 6 is not essential for mammary gland development
    Sandra L Grimm
    Department of Molecular and Cellular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA
    Breast Cancer Res 8:R29. 2006
    ....
  2. pmc Progesterone receptor and Stat5 signaling cross talk through RANKL in mammary epithelial cells
    Alison E Obr
    PhD, Department of Molecular and Cellular Biology, Baylor College of Medicine, BCM Box 130, One Baylor Plaza, Houston, Texas 77030
    Mol Endocrinol 27:1808-24. 2013
    ..These results show that RANKL is a direct PR target gene and that Stat5a has a novel role as a cofactor in PR-mediated transcriptional signaling in the mammary gland. ..
  3. ncbi request reprint Cell cycle defects contribute to a block in hormone-induced mammary gland proliferation in CCAAT/enhancer-binding protein (C/EBPbeta)-null mice
    Sandra L Grimm
    Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas 77030, USA
    J Biol Chem 280:36301-9. 2005
    ..Collectively, these changes prevent C/EBPbeta-null mammary epithelial cells from responding to hormone-induced proliferative signals...
  4. ncbi request reprint The role of C/EBPbeta in mammary gland development and breast cancer
    Sandra L Grimm
    Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas 77030, USA
    J Mammary Gland Biol Neoplasia 8:191-204. 2003
    ..Thus, C/EBPbeta appears to play a role in the specification of progenitor cell fate not only in the mammary gland, but also in a number of other tissues...
  5. pmc Progesterone receptor directly inhibits β-casein gene transcription in mammary epithelial cells through promoting promoter and enhancer repressive chromatin modifications
    Adam C Buser
    Baylor College of Medicine, Department of Molecular and Cellular Biology, Houston, Texas 77030, USA
    Mol Endocrinol 25:955-68. 2011
    ..These studies define a novel mechanism of steroid receptor-mediated transcriptional repression of a physiologically important gene in mammary gland development and differentiation...
  6. pmc Stop! In the name of transforming growth factor-beta: keeping estrogen receptor-alpha-positive mammary epithelial cells from proliferating
    Sandra L Grimm
    Department of Molecular and Cellular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA
    Breast Cancer Res 8:106. 2006
    ....
  7. ncbi request reprint Disruption of steroid and prolactin receptor patterning in the mammary gland correlates with a block in lobuloalveolar development
    Sandra L Grimm
    Department of Molecular and Cellular Biology, Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA
    Mol Endocrinol 16:2675-91. 2002
    ..Together, these data suggest that C/EBPbeta is a master regulator of mammary epithelial cell fate and that the correct spatial pattern of PR and PrlR expression is a critical determinant of hormone-regulated cell proliferation...
  8. ncbi request reprint Jak2 is an essential tyrosine kinase involved in pregnancy-mediated development of mammary secretory epithelium
    Jonathan M Shillingford
    Laboratory of Genetics and Physiology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
    Mol Endocrinol 16:563-70. 2002
    ..Taken together, our results demonstrate that Jak2 is a critical tyrosine kinase that conveys intracellular signals necessary for proliferation and differentiation of mammary epithelium during pregnancy...