Research Topics
| W Paul GlezenSummaryAffiliation: Baylor College of Medicine Country: USA Publications
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Detail Information
Publications
Commentary: benefits of influenza vaccine in US elderly--new studies raise questionsW Paul Glezen
Department of Molecular Virology and Microbiology, and Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA
Int J Epidemiol 35:352-3. 2006
Herd protection against influenzaW Paul Glezen
MVM Department, Baylor College of Medicine, One Baylor Plaza, MS BCM 280, Houston, TX 77030, United States
J Clin Virol 37:237-43. 2006..School-based clinics could provide a platform for rapid deployment of vaccine accessible to all segments of the population. This strategy could be critical for control of pandemic influenza...
Asthma, influenza, and vaccinationW Paul Glezen
Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX 77030, USA
J Allergy Clin Immunol 118:1199-206; quiz 1207-8. 2006..Universal vaccination of all children in school-based clinics will facilitate control of epidemic influenza and provide an infrastructure for control of future influenza pandemics...
Universal influenza vaccination and live attenuated influenza vaccination of childrenW Paul Glezen
Department of MVM, Baylor College of Medicine, Houston, TX 77030, USA
Pediatr Infect Dis J 27:S104-9. 2008..Systematic delivery of influenza vaccine in school-based and workplace-based clinics would greatly enhance the control of epidemic influenza and help prepare for the next pandemic...
Direct and indirect effectiveness of influenza vaccination delivered to children at school preceding an epidemic caused by 3 new influenza virus variantsW Paul Glezen
Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas 77030, USA
J Infect Dis 202:1626-33. 2010..This field trial examines the effectiveness of school-based clinics for vaccine delivery before an epidemic caused by 3 new influenza virus variants not contained in the vaccine...
Trivalent live attenuated intranasal influenza vaccine administered during the 2003-2004 influenza type A (H3N2) outbreak provided immediate, direct, and indirect protection in childrenPedro A Piedra
Baylor College of Medicine, Department of Molecular Virology and Microbiology, Room 248E, One Baylor Plaza, Houston, TX 77030, USA
Pediatrics 120:e553-64. 2007..The objective of this study was to determine the effectiveness of influenza vaccines for healthy school-aged children when administered during the influenza outbreak...
Improving influenza immunization in pregnant women and healthcare workersMelanie E Mouzoon
Kelsey Seybold Clinic, Houston, TX, USA
Am J Manag Care 16:209-16. 2010..To evaluate the effect of several strategies to increase influenza immunization in a multispecialty clinic...
Live attenuated influenza vaccine, trivalent, is safe in healthy children 18 months to 4 years, 5 to 9 years, and 10 to 18 years of age in a community-based, nonrandomized, open-label trialPedro A Piedra
Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas 77030, USA
Pediatrics 116:e397-407. 2005....
Picornavirus, the most common respiratory virus causing infection among patients of all ages hospitalized with acute respiratory illnessRobert L Atmar
Viral Respiratory Pathogens Research Unit and the Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA
J Clin Microbiol 50:506-8. 2012..The molecular assays doubled the number of infections identified; picornaviruses were the most frequent in patients of all ages, followed by respiratory syncytial virus and influenza viruses...
Herd immunity in adults against influenza-related illnesses with use of the trivalent-live attenuated influenza vaccine (CAIV-T) in childrenPedro A Piedra
Department of Molecular Virology and Microbiology, Baylor College of Medicine, Rm 248E, One Baylor Plaza, Houston, TX 77030, USA
Vaccine 23:1540-8. 2005..Vaccination of approximately 20-25% of children, 1.5-18 years of age in the intervention communities resulted in an indirect protection of 8-18% against MAARI in adults > or =35 years of age...
Medically attended pediatric influenza during the resurgence of the Victoria lineage of influenza B virusLadonna K Hite
Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA
Int J Infect Dis 11:40-7. 2007..During the 2002-2003 season, a new variant of influenza B co-circulated with influenza A viruses. This study examines the characteristics and outcomes of children with influenza A and B virus infection vs. other acute respiratory illnesses...
The changing epidemiology of respiratory syncytial virus and influenza: impetus for new control measuresW Paul Glezen
Departments of Molecular Virology and Microbiology and of Pediatrics, Baylor College of Medicine, Houston, TX, USA
Pediatr Infect Dis J 23:S202-6. 2004..New approaches to control will be necessary to reduce impact of these infections. These include earlier availability of influenza vaccine each autumn and use of antivirals and new vaccines for RSV...
Control of influenzaW Paul Glezen
Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas 77030 3498, USA
Tex Heart Inst J 31:39-41. 2004..The availability of the live, attenuated, cold-adapted nasal spray vaccine should facilitate this goal...
Cold-adapted, live attenuated influenza vaccineW Paul Glezen
Department of Molecular Virology and Microbiology, Baylor College of Medicine, One Baylor Plaza, Mail Stop BCM 280, Houston, TX 77030 3498, USA
Expert Rev Vaccines 3:131-9. 2004..Use of CAIV-T in children will not only decrease the risk of serious disease, but also dampen the spread of the virus in the community and reduce exposure of patients who are at high risk of complications and death...
Respiratory viral infections in patients with chronic, obstructive pulmonary diseaseJ David Beckham
Department of Medicine, Baylor College of Medicine and Ben Taub General Hospital, One Baylor Plaza, Houston, TX 77030, USA
J Infect 50:322-30. 2005..CONCLUSIONS: Respiratory viral infections are commonly associated with acute respiratory illness in COPD patients, and the use of RT-PCR assays significantly increases the ability to diagnose these infections...
Safety of influenza vaccination during pregnancyFlor M Munoz
Baylor College of Medicine, Department of Pediatrics and Molecular Virology, Houston, TX 77030, USA
Am J Obstet Gynecol 192:1098-106. 2005..The purpose of this study was to evaluate the safety of influenza vaccine that is administered in the second or third trimester of gestation...
New vaccines for old diseases: trivalent cold-adapted influenza vaccineW Paul Glezen
Department of Molecular Virology and Microbiology, and Pediatrics, Baylor College of Medicine, Houston, TX 77030-3498, USA
Pediatr Ann 33:545-50. 2004..The number of excess deaths is expected to double within the next 25 years if control methods are not intensified. CAIV-T may become an important adjunct to control measures and can facilitate influenza pandemic preparedness...
Correlates of immunity to respiratory syncytial virus (RSV) associated-hospitalization: establishment of minimum protective threshold levels of serum neutralizing antibodiesPedro A Piedra
Department of Molecular Virology and Microbiology, Baylor College of Medicine, Rm 248E, One Baylor Plaza, Houston, TX, USA
Vaccine 21:3479-82. 2003..To determine if respiratory syncytial virus (RSV) specific, serum antibody titers correlate with protection against RSV associated-hospitalization at all ages...
Session IV. Ethical, liability and regulatory issuesW Paul Glezen
Molecular Virology, Microbiology and Pediatric Influenza Research Center, Baylor College of Medicine, One Baylor Plaza Suite 221 D, Houston, TX 77030, USA
Vaccine 21:3501-2. 2003
Influenza vaccination for healthy childrenW Paul Glezen
Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas 77030 3498, USA
Curr Opin Infect Dis 15:283-7. 2002..The new live attenuated nasal spray influenza vaccine is particularly effective in healthy children who would benefit most from universal immunization...
Effect of maternal antibodies on the infant immune responseW Paul Glezen
Department of Molecular Virology and Microbiology, Baylor College of Medicine, One Baylor Plaza, Mail Stop BCM 280, Houston, TX 77030, USA
Vaccine 21:3389-92. 2003..No evidence for the development of fetal tolerance after immunization during pregnancy has occurred subsequently in infants following active vaccination...
Safety of the intranasal, trivalent, live attenuated influenza vaccine (LAIV) in children with intermittent wheezing in an open-label field trialManjusha J Gaglani
Section of Pediatric Infectious Diseases, Department of Pediatrics, Scott and White Memorial Hospital and Clinic, Texas A and M University Health Science Center College of Medicine, Temple, TX 76508, USA
Pediatr Infect Dis J 27:444-52. 2008..Safety of the intranasal, trivalent, live attenuated influenza vaccine (LAIV) in children with asthma is unknown. A previous report showed an "asthma signal" in children aged 18-35 months...
Efficacy of trivalent, cold-adapted, influenza virus vaccine against influenza A (Fujian), a drift variant, during 2003-2004M Elizabeth Halloran
Program in Biostatistics and Biomathematics, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
Vaccine 25:4038-45. 2007..LAIV-T was cross-protective with a drift variant strain in 2003-2004, evidence that such vaccines could be important for preparing for a pandemic and for annual influenza...
Influenza controlW Paul Glezen
N Engl J Med 355:79-81. 2006
Direct and total effectiveness of the intranasal, live-attenuated, trivalent cold-adapted influenza virus vaccine against the 2000-2001 influenza A(H1N1) and B epidemic in healthy childrenManjusha J Gaglani
Section of Pediatric Infectious Diseases, Department of Pediatrics, Scott and White Memorial Hospital and Clinic, The Texas A and M University System Health Science Center College of Medicine, Temple, 76508, USA
Arch Pediatr Adolesc Med 158:65-73. 2004....
A personnel time-motion study of intranasal influenza vaccination in healthy childrenMichael L Washington
Health Services Research and Evaluation Branch, Immunization Services Division, MS E52, Atlanta, GA 30329, USA
Vaccine 23:4879-85. 2005..Total family visit time decreased by 64 s if the youngest child was receiving a second dose. Alternative delivery systems (e.g., group visits) are needed to take advantage of short vaccination times...
Estimating efficacy of trivalent, cold-adapted, influenza virus vaccine (CAIV-T) against influenza A (H1N1) and B using surveillance culturesM Elizabeth Halloran
Department of Biostatistics, Rollins School of Public Health, Emory University, 1518 Clifton Road NE, Atlanta, GA 30322, USA
Am J Epidemiol 158:305-11. 2003..CAIV-T provides substantial protection against a mixture of influenza A (H1N1) and B. Results demonstrate the powerful potential of using validation sets for outcomes in vaccine field studies...
Safety of cold-adapted live influenza vaccineW Paul Glezen
Pediatr Infect Dis J 23:593-4; author reply 594. 2004
Estimating deaths due to influenza and respiratory syncytial virusW Paul Glezen
JAMA 289:2500; author reply 2500-2. 2003
Immunogenic protein contaminants in pneumococcal vaccinesJigui Yu
Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35294, USA
J Infect Dis 187:1019-23. 2003..The degree of contamination was highly variable, and this should be considered in pneumococcal vaccine evaluations or when capsular polysaccharide is used for pneumococcal antibody assays...
