AHMED OSAMA GABERSummaryAffiliation: Baylor College of Medicine Country: USA Publications
Research Grants
| Collaborators
|
Detail Information
Publications
Ipsilateral placement in double-kidney transplantationA Osama Gaber
Department of Surgery, The University of Tennessee Health Science Center, Memphis, TN, USA
Transplantation 84:929-31. 2007..In the recipient, the incision should allow complete dissection of the common external and internal iliac arteries. This report provides a detail of the technique used for ipsilateral placement of double kidneys...- Comparison of sirolimus plus tacrolimus versus sirolimus plus cyclosporine in high-risk renal allograft recipients: results from an open-label, randomized trialA Osama Gaber
Methodist University Hospital, Memphis, TN, USA
Transplantation 86:1187-95. 2008..The efficacy and safety of sirolimus (SRL) plus tacrolimus (TAC) versus SRL plus cyclosporine (CsA) were compared in high-risk renal allograft recipients... - Long-term experience with simultaneous kidney-pancreas transplantation with portal-enteric drainage and tacrolimus/mycophenolate mofetil-based immunosuppressionRobert J Stratta
Departments of Surgery-Transplant, University of Tennessee, Memphis, TN, USA. rstratta@ wfubmc.edu
Clin Transplant 17:69-77. 2003..CONCLUSION: These findings suggest that SKPT with P-E drainage and contemporary immunosuppression may result in excellent intermediate-term outcomes... - Prospective, randomized trial of the effect of antibody induction in simultaneous pancreas and kidney transplantation: three-year resultsGeorge W Burke
Department of Surgery, University of Miami, Miami, Florida 33136, USA
Transplantation 77:1269-75. 2004..Induction agents included T-cell-depleting and interleukin-2 receptor antibodies... - Observations regarding the use of sirolimus and tacrolimus in high-risk cadaveric renal transplantationAgnes Lo
Departments of a Pharmacy, University of Tennessee Health Science Center, Memphis, TN 38163, USA
Clin Transplant 18:53-61. 2004..We have discontinued recruitment of patients to the standard tacrolimus and reduced sirolimus combination and we have tightened our criteria for selection of marginal donor kidneys with our high-risk renal transplant recipients... - Comparing an early corticosteroid/late calcineurin-free immunosuppression protocol to a sirolimus-, cyclosporine A-, and prednisone-based regimen for pancreas-kidney transplantationRichard J Knight
Department of Surgery, The Methodist Hospital, Houston, TX 77030, USA
Transplantation 89:727-32. 2010..A prednisone and calcineurin inhibitor (CNI)-free protocol was compared with a sirolimus, cyclosporine A (CsA), and prednisone-based immunosuppressive regimen for simultaneous pancreas-kidney transplantation (SPK)... - Diagnosis of de novo localized thrombotic microangiopathy by surveillance biopsyM Colleen Hastings
Department of Pediatrics, University of Tennessee Health Science Center UTHSC, Memphis, TN, USA
Pediatr Nephrol 22:742-6. 2007..This patient had resolution of the renal lesion following conversion from tacrolimus to sirolimus-based immunosuppression... - Evaluation of an immunosuppressant side effect instrumentRebecca P Winsett
University of Tennessee Health Science Center, Memphis, Tenn, USA
Prog Transplant 14:210-6, 240. 2004..We Were asked to develop an instrument to measure side effects in immunosuppressed transplant recipients... - Comparison of sirolimus-based calcineurin inhibitor-sparing and calcineurin inhibitor-free regimens in cadaveric renal transplantationAgnes Lo
Department of Pharmacy, University of Tennessee Health Science Center, Memphis, Tennessee, USA
Transplantation 77:1228-35. 2004..The CI-free regimen is associated with better renal function at 1 year post-transplant. Long-term follow-up will aid in determining the risk and benefit ratio of these regimens... 
Rabbit antithymocyte globulin (thymoglobulin): 25 years and new frontiers in solid organ transplantation and haematologyA Osama Gaber
Department of Surgery, The Methodist Hospital, Houston, Texas 77030, USA
Drugs 70:691-732. 2010..Advances in the understanding of the multifaceted mechanism of action will guide research into new therapeutic areas and future applications...- Thymoglobulin for induction or rejection therapy in pancreas allograft recipients: a single centre experienceJennifer Trofe
Department of Pharmacy, University of Tennessee-Memphis, Memphis, TN, USA
Clin Transplant 16:34-44. 2002..Dose adjustments were required in over half the cases and were usually due to leukopenia. Infections occurring subsequent to thymoglobulin were not uncommon and reflected the immunosuppressive burden of the patient population... - Quantitative detection of T-cell activation markers by real-time PCR in renal transplant rejection and correlation with histopathologic evaluationOmaima Sabek
Department of Surgery, College of Medicine, University of Tennessee, Memphis 38163, USA
Transplantation 74:701-7. 2002..This is also the first report on the possible utility of HLA-DRA mRNA up-regulation as a marker for kidney transplant rejection... - Clinical utility of histological features of polyomavirus allograft nephropathyLillian W Gaber
Department of Pathology, College of Medicine, University of Tennessee Health Science Center, Memphis, 38163, USA
Transplantation 82:196-204. 2006..The purpose of this study was to determine if histological features of polyomavirus allograft nephropathy (PVAN) are associated with the clinical presentation and outcomes of PVAN... - Analysis of liver transplant outcomes for United Network for Organ Sharing recipients 60 years old or older identifies multiple model for end-stage liver disease-independent prognostic factorsThomas A Aloia
Division of Transplantation, Department of Surgery, Weill Cornell Medical College, Methodist Hospital, Houston, TX 77030, USA
Liver Transpl 16:950-9. 2010..By optimization of donor selection for recipients over the age of 60 years, clinical utilization of the ORPS model may enhance organ utilization for all patients awaiting OLT... - The effect of isolation methods and the use of different enzymes on islet yield and in vivo functionOmaima M Sabek
Department of Surgery, The Methodist Hospital, Houston, TX 77030, USA
Cell Transplant 17:785-92. 2008..Our results show that although there is no different in islet yield, purity, and integrity between different enzymes using the same method, hand-shaking method yields more islets with better integrity than mechanical-shaking method... - A prospective, randomized, double-blind, placebo-controlled multicenter trial comparing early (7 day) corticosteroid cessation versus long-term, low-dose corticosteroid therapyE Steve Woodle
Division of Transplantation, Department of Surgery, University of Cincinnati, Cincinnati, OH 45267, USA
Ann Surg 248:564-77. 2008..To compare outcomes with early corticosteroid withdrawal (CSWD) and chronic low dose corticosteroid therapy (CCS)... - Changes in weight during the first year after kidney transplantationAnn K Cashion
University of Tennessee Health Science Center, Memphis, TN, USA
Prog Transplant 17:40-7. 2007..Obesity frequently occurs following kidney transplantation and is of concern because of the associated risk for cardiovascular complications... - The effect of donor factors on human islet yield and their in vivo functionOmaima M Sabek
University of Tennessee Health Science Centre, Memphis, USA
Prog Transplant 16:350-4. 2006..CONCLUSIONS: These data demonstrate that although yield is affected by a variety of donor factors and enzyme mixes, these factors do not affect islet in vivo function... - Impact of hepatitis C virus status in pancreas transplantation: a case controlled studyMarsha R Honaker
Department of Pharmacy, University of Tennessee, Memphis, TN 38163, USA
Clin Transplant 16:243-51. 2002..Further studies with more patients and longer follow-up are needed to fully define the impact of HCV status on pancreas graft survival and function... - Preservation of human pancreatic islet in vivo function after 6-month culture in serum-free mediaBenjamin T Rush
Department of Surgery, College of Medicine, University of Tennessee Health Science Center, Memphis, TN 38163, USA
Transplantation 77:1147-54. 2004..The ability to maintain islets in culture for prolonged periods is an important step toward the development of islet tissue repositories and distribution centers... - The effect of CYP3A5 and MDR1 polymorphic expression on cyclosporine oral disposition in renal transplant patientsCharles R Yates
University of Tennessee Health Science Center, Department of Pharmaceutical Sciences, 874 Union Avenue, Crowe Building Room 5P, Memphis, TN 38163, USA
J Clin Pharmacol 43:555-64. 2003..Thus, the MDR1 C3435T genotype offers a potential mechanistic basis to explain interracial differences in CsA oral bioavailability. Further studies are needed to explore the relationship between CYP3A5 and MDR1 genotype and phenotype... - Renal allograft loss as the result of polyomavirus interstitial nephritis after simultaneous kidney-pancreas transplantation: results with kidney retransplantationAhmed H Al-Jedai
Department of Pharmacy, University of Tennessee-Memphis, Memphis, TN, USA
Transplantation 75:490-4. 2003..CONCLUSIONS: Although follow-up is limited, our initial experience would indicate that graft loss secondary to PV interstitial nephritis is not an absolute contraindication for kidney retransplantation... - A review of the evidence for use of thymoglobulin induction in renal transplantationA Osama Gaber
Methodist Transplant Center, Department of Surgery, The Methodist Hospital, Houston, Texas 77030, USA
Transplant Proc 42:1395-400. 2010..This review describes the evidence supporting the use of depleting ATGs in kidney transplantation...
Research Grants
- ENHANCEMENT OF HUMAN ISLET ENGRAFTMENT BY GENE THERAPYA Gaber; Fiscal Year: 2003..Future experiments based on the findings of this research would allow us to examine the utility of other gene candidates or other vectors that could complement our gene therapy program in islet transplantation. ..
- IMPACT OF STANDARDIZATION AND PROCEDURE OPTIMIZATION ON*Ahmed Gaber; Fiscal Year: 2005..This team has worked well together with the aim of curing diabetes through islet transplantation. ..
- Effect of Dietary Supplements in African American Kidney Transplant RecipientsAhmed Gaber; Fiscal Year: 2007..The long-term objective of the proposed research is to improve the graft and patient survival of African American recipients of kidney transplants through nutritional supplementation of the immunosuppressive regimen. ..