Adriano Flora

Summary

Affiliation: Baylor College of Medicine
Country: USA

Publications

  1. pmc The E-protein Tcf4 interacts with Math1 to regulate differentiation of a specific subset of neuronal progenitors
    Adriano Flora
    Howard Hughes Medical Institute, Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA
    Proc Natl Acad Sci U S A 104:15382-7. 2007
  2. pmc In vivo Atoh1 targetome reveals how a proneural transcription factor regulates cerebellar development
    Tiemo J Klisch
    Department of Molecular and Human Genetics, The Howard Hughes Medical Institute, The Dan L Duncan Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA
    Proc Natl Acad Sci U S A 108:3288-93. 2011
  3. pmc Math1 is essential for the development of hindbrain neurons critical for perinatal breathing
    Matthew F Rose
    Program in Developmental Biology, Baylor College of Medicine, Houston, TX 77030, USA
    Neuron 64:341-54. 2009
  4. pmc Deletion of Atoh1 disrupts Sonic Hedgehog signaling in the developing cerebellum and prevents medulloblastoma
    Adriano Flora
    Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA
    Science 326:1424-7. 2009
  5. pmc Exercise and genetic rescue of SCA1 via the transcriptional repressor Capicua
    John D Fryer
    Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA
    Science 334:690-3. 2011
  6. pmc The expression of the human neuronal alpha3 Na+,K+-ATPase subunit gene is regulated by the activity of the Sp1 and NF-Y transcription factors
    Roberta Benfante
    Department of Pharmacology, School of Medicine, University of Milan, 32 via Vanvitelli, 20129 Milan, Italy
    Biochem J 386:63-72. 2005
  7. ncbi PHOX2B regulates its own expression by a transcriptional auto-regulatory mechanism
    Francesca Cargnin
    Department of Pharmacology, School of Medicine, University of Milan, Italy
    J Biol Chem 280:37439-48. 2005
  8. ncbi Transcription factor PHOX2A regulates the human alpha3 nicotinic receptor subunit gene promoter
    Roberta Benfante
    Department of Pharmacology, School of Medicine, University of Milan, 20129 Milan, Italy
    J Biol Chem 282:13290-302. 2007

Collaborators

  • Huda Zoghbi
  • Wei Li
  • Roberta Benfante
  • Tiemo J Klisch
  • Diego Fornasari
  • Francesco Clementi
  • Francesca Cargnin
  • John D Fryer
  • Matthew F Rose
  • Renato Longhi
  • Simona Di Lascio
  • Liguo Wang
  • Peng Yu
  • Yuanxin Xi
  • Hyojin Kang
  • Juan Crespo-Barreto
  • Chad Shaw
  • Angela N Carter
  • Yan Gao
  • Harry T Orr
  • Caleigh Mandel-Brehm
  • Jun Ren
  • Kaashif A Ahmad
  • John J Greer
  • Hsiao Tuan Chao
  • Sara Colombo
  • Elena Battaglioli
  • Fabian Chen
  • Ruth Adele Antonini
  • Monica Vaccari

Detail Information

Publications8

  1. pmc The E-protein Tcf4 interacts with Math1 to regulate differentiation of a specific subset of neuronal progenitors
    Adriano Flora
    Howard Hughes Medical Institute, Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA
    Proc Natl Acad Sci U S A 104:15382-7. 2007
    ....
  2. pmc In vivo Atoh1 targetome reveals how a proneural transcription factor regulates cerebellar development
    Tiemo J Klisch
    Department of Molecular and Human Genetics, The Howard Hughes Medical Institute, The Dan L Duncan Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA
    Proc Natl Acad Sci U S A 108:3288-93. 2011
    ..This study expands current thinking about the transcriptional activities driving neuronal differentiation and provides a framework for further neurodevelopmental studies...
  3. pmc Math1 is essential for the development of hindbrain neurons critical for perinatal breathing
    Matthew F Rose
    Program in Developmental Biology, Baylor College of Medicine, Houston, TX 77030, USA
    Neuron 64:341-54. 2009
    ..This study identifies Math1-dependent neurons that are critical for perinatal breathing that may link proprioception and arousal with respiration...
  4. pmc Deletion of Atoh1 disrupts Sonic Hedgehog signaling in the developing cerebellum and prevents medulloblastoma
    Adriano Flora
    Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA
    Science 326:1424-7. 2009
    ..Our data shed light on the function of Atoh1 in postnatal cerebellar development and identify a new mechanism that can be targeted to regulate medulloblastoma formation...
  5. pmc Exercise and genetic rescue of SCA1 via the transcriptional repressor Capicua
    John D Fryer
    Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA
    Science 334:690-3. 2011
    ..Thus, exercise might have long-term beneficial effects in other ataxias and neurodegenerative diseases...
  6. pmc The expression of the human neuronal alpha3 Na+,K+-ATPase subunit gene is regulated by the activity of the Sp1 and NF-Y transcription factors
    Roberta Benfante
    Department of Pharmacology, School of Medicine, University of Milan, 32 via Vanvitelli, 20129 Milan, Italy
    Biochem J 386:63-72. 2005
    ..Although the expression of these factors is not tissue-specific, co-operative functional interactions among them are required to direct the activity of the promoter predominantly in neuronal cells...
  7. ncbi PHOX2B regulates its own expression by a transcriptional auto-regulatory mechanism
    Francesca Cargnin
    Department of Pharmacology, School of Medicine, University of Milan, Italy
    J Biol Chem 280:37439-48. 2005
    ....
  8. ncbi Transcription factor PHOX2A regulates the human alpha3 nicotinic receptor subunit gene promoter
    Roberta Benfante
    Department of Pharmacology, School of Medicine, University of Milan, 20129 Milan, Italy
    J Biol Chem 282:13290-302. 2007
    ..As the alpha3 subunit is expressed in every terminally differentiated ganglionic cell, this is the first example of a "pan-autonomic" gene whose expression is regulated by PHOX2 proteins...