Research Topics
| D M DoughertySummaryAffiliation: Baylor College of Medicine Country: USA Publications
| Collaborators
|
Detail Information
Publications
Possible amotivational effects following marijuana smoking under laboratory conditionsDon R Cherek
Department of Psychiatry and Behavioral Sciences, University of Texas Houston, Health Science Center, 77030, USA
Exp Clin Psychopharmacol 10:26-38. 2002..Increasing the monetary value of the reinforcer diminished the acute marijuana effects on PR responding, suggesting that marijuana exerted an effect primarily on reinforcers of a smaller magnitude...
Commission error rates on a continuous performance test are related to deficits measured by the Benton Visual Retention TestDonald M Dougherty
Neurobehavioral Research Laboratory and Clinic, Department of Psychiatry and Behavioral Sciences, University of Texas Health Science Center at Houston, 77030, USA
Assessment 10:3-12. 2003..These results may be explained by a shared association between processes of impulsivity and other deficits of executive control that may interfere with successful performance of the Benton...
Familial transmission of Continuous Performance Test behavior: attentional and impulsive response characteristicsDonald M Dougherty
Neurobehavioral Research Laboratory and Clinic, Department of Psychiatry and Behavioral Sciences, The University of Texas Health Science Center at Houston, 77030, USA
J Gen Psychol 130:5-21. 2003..e., BIS) was correlated with commission errors for parents, but not for adolescents. The findings of this study support the use of an objective behavioral measure of impulsivity to assess familial relationships of impulsivity...
Age at first drink relates to behavioral measures of impulsivity: the immediate and delayed memory tasksDonald M Dougherty
University of Texas Health Science Center at Houston, Neurobehavioral Research Laboratory and Clinic, Houston, Texas 77030, USA
Alcohol Clin Exp Res 28:408-14. 2004..This study examined the relationship between laboratory-measured impulsivity and age at first drink...
Immediate and delayed memory tasks: a computerized behavioral measure of memory, attention, and impulsivityDonald M Dougherty
Neurobehavioral Research Laboratory and Clinic, Department of Psychiatry and Behavioral Sciences, University of Texas Health Science Center at Houston, 1300 Moursund Street, Houston, TX 77030, USA
Behav Res Methods Instrum Comput 34:391-8. 2002..Preliminary studies have demonstrated that these laboratory tasks are sensitive to group differences, produce stable baselines of performance, and are sensitive to drug-induced performance decrements...
Behavioral impulsivity paradigms: a comparison in hospitalized adolescents with disruptive behavior disordersDonald M Dougherty
Neurobehavioral Research Laboratory and Clinic, Department of Psychiatry and Behavioral Sciences, The University of Texas Health Science Center at Houston, 77030 3406, USA
J Child Psychol Psychiatry 44:1145-57. 2003..As a result, comparisons between measures are difficult, with little consensus regarding which method may be most sensitive to individual impulsivity differences of different populations...
Effects of moderate and high doses of alcohol on attention, impulsivity, discriminability, and response bias in immediate and delayed memory task performanceD M Dougherty
Department of Psychiatry and Behavioral Sciences, University of Texas Houston Health Science Center 77030, USA
Alcohol Clin Exp Res 24:1702-11. 2000..The first is important because previous studies have shown little effect of alcohol on attention, and the second is important because commission errors have been related to impulsive behaviors...
Laboratory measures of aggression and impulsivity in women with borderline personality disorderD M Dougherty
Department of Psychiatry and Behavioral Sciences, Harris County Psychiatric Center, University of Texas, Houston 77030, USA
Psychiatry Res 85:315-26. 1999..Aggressive responding rates correlated positively with BDHI scores. These results extend previous findings that negative affect in women is reflected in laboratory behavioral measures...
Immediate versus delayed visual memory task performance among schizophrenic patients and normal control subjectsD M Dougherty
Harris County Psychiatric Center, Department of Psychiatry and Behavioral Sciences, University of Texas at Houston Health Science Center, 77030, USA
Psychiatry Res 79:255-65. 1998..This paradigm may prove useful in discriminating subtle differences in immediate and delayed memory capability among psychiatric populations and normal control subjects...
Influence of trait hostility on tryptophan depletion-induced laboratory aggressionD M Dougherty
Department of Psychiatry and Behavioral Sciences, University of Texas Houston Medical School, 77030, USA
Psychiatry Res 88:227-32. 1999..These preliminary data support earlier findings that compared to non-hostile men, hostile men may be more prone to behavior change induced by the perturbation of the 5-HT neurotransmitter system...
Endogenous plasma testosterone levels and commission errors in women: A preliminary reportJ M Bjork
Neurobehavioral Research Laboratory and Clinic, Department of Psychiatry and Behavioral Sciences, University of Texas-Houston Medical School, 1300 Moursund, Houston, TX 77030, USA
Physiol Behav 73:217-21. 2001..In light of the fact previous studies find commission errors on the CPT are associated with impulsivity, the results of this study support a positive relationship between testosterone and impulsivity...
Alcohol increases commission error rates for a continuous performance testD M Dougherty
Department of Psychiatry and Behavioral Sciences, University of Texas Houston Health Science Center 77030, USA
Alcohol Clin Exp Res 23:1342-51. 1999..e., (1) perhaps because of the ease of the task used in previous experiments, alcohol has not been found to impair performance, and (2) CPT commission errors (described below) have been related to impulsive behavior...
Laboratory measurement of adaptive behavior change in humans with a history of substance dependenceS D Lane
Department of Psychiatry and Behavioral Sciences, University of Texas Health Science Center Houston 77030, USA
Drug Alcohol Depend 51:239-52. 1998..These data suggest a deficiency in adaptive behavior change, particularly when that change requires an abrupt slowing of response rates following a brief history of high-rate responding...
Ipsapirone neuroendocrine challenge: relationship to aggression as measured in the human laboratoryF G Moeller
Department of Psychiatry and Behavioral Sciences, University of Texas Houston Health Science Center, 77030, USA
Psychiatry Res 81:31-8. 1998..This study supports a relationship between serotonin function and aggression as measured in the human laboratory, similar to the well-documented association between self-reported aggression and serotonin...
Measurement of inter-episode impulsivity in bipolar disorderA C Swann
Department of Psychiatry and Behavioral Sciences, University of Texas Houston Medical School, 77030, USA
Psychiatry Res 101:195-7. 2001..Laboratory measurements of impulsivity correlated with a BIS-11 score or severity of manic symptoms. Impulsivity in bipolar disorder may have both stable and state-dependent aspects...
The influence of menstrual-cycle phase on the relationship between testosterone and aggressionD M Dougherty
Department of Psychiatry and Behavioral Sciences, The University of Texas, Houston 77030, USA
Physiol Behav 62:431-5. 1997..self-report of perimenstrual symptomatology is a more consistent predictor of aggressive behavior across the menstrual cycle than plasma testosterone; and 3. perimenstrual emotional symptomatology is not related to testosterone levels...
Psychiatric aspects of impulsivityF G Moeller
Department of Psychiatry and Behavioral Sciences, University of Texas Houston Health Science Center, 77030, USA
Am J Psychiatry 158:1783-93. 2001..The authors discuss the relationship of impulsivity to psychiatric disorders and present selected hypotheses regarding the reasons for these relationships...
Plasma L-tryptophan depletion and aggressionD M Dougherty
Department of Psychiatry and Behavioral Sciences, University of Texas Houston Medical School 77030, USA
Adv Exp Med Biol 467:57-65. 1999..Extending these studies to women appears to be the much-needed next step given that serotonergic levels appear to vary both as a function of the menstrual cycle phase and menstrual symptomatology...
Low dose zolmitriptan as a 5-HT neuroendocrine challenge agent in humansF G Moeller
Department of Psychiatry and Behavioral Sciences, University of Texas Houston Health Science Center, Houston 77030, USA
Psychoneuroendocrinology 25:607-18. 2000..The neuroendocrine effects of 2.5 mg of orally administered zolmitriptan are similar to previously reported effects of sumatriptan, with minimal side effects...
The impact of impulsivity on cocaine use and retention in treatmentF G Moeller
Department of Psychiatry and Behavioral Sciences, University of Texas Houston Health Science Center, Houston, TX 77030, USA
J Subst Abuse Treat 21:193-8. 2001..This study shows that impulsivity is a significant predictor of cocaine use and treatment retention, and suggests the need for targeting impulsivity in cocaine dependence treatment...
Antisocial personality disorder, alcohol, and aggressionF G Moeller
Department of Psychiatry and Behavioral Sciences, University of Texas-Houston, USA
Alcohol Res Health 25:5-11. 2001..Alternatively, the association between ASPD and alcohol-related aggression may stem from some as yet undetermined factor(s) that increase the risk for aggression in general...
Laboratory measured behavioral impulsivity relates to suicide attempt historyDonald M Dougherty
Neuro behavioral Research Laboratory and Clinic, Department of Psychiatry and Behavioral Medicine, Wake Forest University Health Sciences, Winston Salem, North Carolina 27157, USA
Suicide Life Threat Behav 34:374-85. 2004..This study helps to demonstrate how laboratory behavioral measures of impulsivity can be used to discriminate groups based on suicidal histories among samples not currently exhibiting significant suicidal behaviors...
Acute yohimbine increases laboratory-measured impulsivity in normal subjectsAlan C Swann
Department of Psychiatry and Behavioral Sciences, University of Texas Health Science Center, Houston, Texas 77030, USA
Biol Psychiatry 57:1209-11. 2005....
Reduced anterior corpus callosum white matter integrity is related to increased impulsivity and reduced discriminability in cocaine-dependent subjects: diffusion tensor imagingFrederick Gerard Moeller
Department of Psychiatry and Behavioral Sciences, University of Texas Health Science Center at Houston, Houston, TX 77030, USA
Neuropsychopharmacology 30:610-7. 2005....
Laboratory behavioral measures of impulsivityDonald M Dougherty
Department of Psychiatry and Behavioral Medicine, School of Medicine, Wake Forest University Health Sciences, Medical Center Blvd, Winston Salem, NC 27157, USA
Behav Res Methods 37:82-90. 2005..The four paradigms in this software package are available at no cost and can be obtained by contacting the corresponding author...
Increased impulsivity associated with severity of suicide attempt history in patients with bipolar disorderAlan C Swann
Department of Psychiatry, University of Texas Medical School at Houston, 1300 Moursund, Rm 270, Houston, TX 77030, USA
Am J Psychiatry 162:1680-7. 2005..The purpose of this study was to investigate the relationship between impulsivity and severity of past suicidal behavior, a potential predictor of eventual suicide, in patients with bipolar disorder...
The effects of alcohol on laboratory-measured impulsivity after L: -Tryptophan depletion or loadingDonald M Dougherty
Neurobehavioral Research Laboratory and Clinic, Department of Psychiatry and Behavioral Medicine, Wake Forest University Health Sciences, Medical Center Boulevard, Winston Salem, NC 27157, USA
Psychopharmacology (Berl) 193:137-50. 2007....
Characterizing aggressive behavior with the Impulsive/Premeditated Aggression Scale among adolescents with conduct disorderCharles W Mathias
Neurobehavioral Research Laboratory and Clinic, Department of Psychiatry and Behavioral Medicine, Wake Forest University Health Sciences, Medical Center Boulevard, Winston Salem, NC 27157, USA
Psychiatry Res 151:231-42. 2007..As in the adult and child literature, characterization of aggressive behavior into two subtypes appears to be relevant to understanding individual differences among adolescents with Conduct Disorder...
Manic symptoms and impulsivity during bipolar depressive episodesAlan C Swann
Department of Psychiatry and Behavioral Sciences, University of Texas Health Science Center, Houston, TX 77030, USA
Bipolar Disord 9:206-12. 2007..Therefore, we investigated the prevalence of manic symptoms and their relationships to impulsivity and clinical characteristics in patients with bipolar depressive episodes...
Impulsive and premeditated subtypes of aggression in conduct disorder: differences in time estimationDonald M Dougherty
Department of Psychiatry and Behavioral Medicine, Neurobehavioral Research Laboratory and Clinic, Wake Forest University School of Medicine Winston Salem, North Carolina 27157, USA
Aggress Behav 33:574-82. 2007..This study confirms the importance of considering the role and type of physical aggression when studying heterogeneous diagnostic groups like CD and supports the relevance of time estimation to certain subgroups of adolescents with CD...
A test of alcohol dose effects on multiple behavioral measures of impulsivityDonald M Dougherty
Neurobehavioral Research Laboratory and Clinic, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA
Drug Alcohol Depend 96:111-20. 2008..Acute alcohol administration affects impulsive behavior, although these effects vary as a function of alcohol dose, assessment instrument, and time of measurement following administration...
Suicidal behaviors and drug abuse: impulsivity and its assessmentDonald M Dougherty
Neurobehavioral Research Laboratory and Clinic, Department of Psychiatry and Behavioral Sciences, The University of Texas Health Science Center at Houston, 1300 Moursund Street, Houston, TX 77030, USA
Drug Alcohol Depend 76:S93-S105. 2004..To better account for influence of impulsivity in these psychiatric disturbances, no single source of measurement should be used without the consideration of other types of instruments...
Serotonin 2a receptor T102C polymorphism and impaired impulse controlJames M Bjork
Neurobehavioral Research Laboratory and Clinic, Department of Psychiatry and Behavioral Sciences, University of Texas Houston Medical School, Houston, Texas 77030, USA
Am J Med Genet 114:336-9. 2002..These preliminary data suggest that the T102C 5-HT2a receptor polymorphism may be a marker for impaired behavior control-perhaps in the context of psychiatric disorder history...
Laboratory-measured aggressive behavior of women: acute tryptophan depletion and augmentationDawn M Marsh
Department of Psychiatry and Behavioral Sciences, University of Texas Health Science Center at Houston, 1300 Moursund Street, Houston, TX 77030, USA
Neuropsychopharmacology 26:660-71. 2002..These findings indicate that both T+ and T- can influence aggressive behavior and that certain subgroups of women may be more susceptible to serotonin manipulation...
Increased impulsivity in cocaine dependent subjects independent of antisocial personality disorder and aggressionF Gerard Moeller
Department of Psychiatry and Behavioral Sciences, University of Texas Health Science Center Houston, 1300 Moursund, Houston, TX 77030, USA
Drug Alcohol Depend 68:105-11. 2002..This study supports the hypothesis that the increased impulsivity as measured by the BIS-11 in cocaine dependent individuals is not exclusively due to concomitant increases in aggression or ASPD...
Reliability estimates for the immediate and delayed memory tasksCharles W Mathias
Neurobehavioral Research Laboratory and Clinic, University of Texas Health Science Center at Houston, 77030, USA
Percept Mot Skills 95:559-69. 2002..Analyses indicated that the primary variable of interest, i.e., commission of errors, showed acceptable reliability within and across testing periods...
Impulsivity and phase of illness in bipolar disorderAlan C Swann
Department of Psychiatry, University of Texas Mental Sciences Institute, University of Texas Health Science Center, Houston, TX, USA
J Affect Disord 73:105-11. 2003..Impulsivity is prominent in bipolar disorder, but there is little quantitative information relating it to phase of illness...
Two models of impulsivity: relationship to personality traits and psychopathologyAlan C Swann
Department of Psychiatry, University of Texas Medical School, Houston, Texas, USA
Biol Psychiatry 51:988-94. 2002..The relationship appears stronger, however, for rapid-response impulsivity, as measured by the IMT/DMT. Laboratory and personality measures of impulsivity appear to be related to risk of psychopathology...
Impulsivity: a link between bipolar disorder and substance abuseAlan C Swann
Department of Psychiatry and Behavioral Sciences, Mental Sciences Institute, Harris County Psychiatric Hospital, University of Texas Health Science Center, Houston, 77030, USA
Bipolar Disord 6:204-12. 2004..Substance abuse is present in most patients with bipolar disorder and associated with poor treatment outcome and increased risk of suicide. Increased impulsivity may be a link between bipolar disorder and substance abuse...
Functional MRI study of working memory in MDMA usersF Gerard Moeller
Department of Psychiatry and Behavioral Sciences, University of Texas Health Science Center Houston, 1300 Moursund, Houston, TX 77030, USA
Psychopharmacology (Berl) 177:185-94. 2004..Similarly, behavioral studies in human MDMA users regularly find abnormalities in memory, mood, and impulse control. However, studies of brain function using brain imaging in MDMA users have been less consistent...
P300 event-related potential amplitude and impulsivity in cocaine-dependent subjectsF Gerard Moeller
Department of Psychiatry and Behavioral Sciences, University of Texas Health Science Center Houston, Moursund, Houston, Texas, USA
Neuropsychobiology 50:167-73. 2004..This study supports the hypothesis that the basic neurophysiology responsible for the P300 amplitude in cocaine-dependent individuals is associated with impulsivity independent of a history of childhood conduct disorder symptoms...
Impulsivity and BOLD fMRI activation in MDMA users and healthy control subjectsIgnacio H Valdes
Department of Psychiatry and Behavioral Sciences, University of Texas Health Science Center at Houston, 1300 Moursund, Houston, TX 77030, USA
Psychiatry Res 147:239-42. 2006..A significant correlation between BIS scores and DLPFC activation was found, supporting a role for the DLPFC in BIS-measured impulsivity...
The biphasic effects of alcohol: comparisons of subjective and objective measures of stimulation, sedation, and physical activityMerideth A Addicott
Department of Radiology, Wake Forest University School of Medicine, Winston Salem, North Carolina, USA
Alcohol Clin Exp Res 31:1883-90. 2007..However, little is known about the effects of alcohol on physical activity or the relationship between physical activity and subjective self-report measures of stimulation and sedation following alcohol consumption in humans...
Personality judgment and personality pathology: self-other agreement in adolescents with conduct disorderR Michael Furr
Department of Psychology, Wake Forest University, NC 27106, USA
J Pers 75:629-62. 2007..Results have implications for understanding the processes affecting personality judgment, for increasing integration of traditional personality research and personality pathology, and for personality assessment...
Teenagers do not always lie: characteristics and correspondence of telephone and in-person reports of adolescent drug useErin E Shannon
Department of Psychiatry and Behavioral Medicine, Wake Forest University School of Medicine, Winston Salem, NC, United States
Drug Alcohol Depend 90:288-91. 2007..Additionally, parents appear to become more aware of their adolescent's drug use with increased frequency of use...
Cannabis withdrawal among adolescent cannabis users in an outpatient research settingMichael A Dawes
Department of Physiology and Pharmacology, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA
Am J Addict 15:485-6. 2006
Overview of workshop on drug abuse and suicidal behaviorLynda Erinoff
Drug Alcohol Depend 76:S3-9. 2004
