Research Topics
Genomes and Genes | Jeannette E DaviesSummaryAffiliation: Baylor College of Medicine Country: USA Publications
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Publications
Astrocytes derived from glial-restricted precursors promote spinal cord repairJeannette E Davies
Department of Neurosurgery, Baylor College of Medicine, 1709 Dryden Street, Suite 750, Houston, Texas 77030, USA
J Biol 5:7. 2006..We reasoned therefore that pre-differentiation of embryonic neural precursors to astrocytes, which are thought to support axon growth in the injured immature CNS, would be more beneficial for CNS repair...
Decorin suppresses neurocan, brevican, phosphacan and NG2 expression and promotes axon growth across adult rat spinal cord injuriesJeannette E Davies
Department of Neurosurgery, Baylor College of Medicine, Scurlock Tower Suite 944, 6560 Fannin Street, Houston, TX 77030, USA
Eur J Neurosci 19:1226-42. 2004....
Transplanted astrocytes derived from BMP- or CNTF-treated glial-restricted precursors have opposite effects on recovery and allodynia after spinal cord injuryJeannette E Davies
Department of Neurosurgery, Anschutz Medical Campus, University of Colorado Denver, Aurora, CO 80045, USA
J Biol 7:24. 2008..This is of particular concern in the case of spinal cord injury, where recent studies have shown that transplanted neuroepithelial stem cells can generate pain syndromes...
Decorin promotes robust axon growth on inhibitory CSPGs and myelin via a direct effect on neuronsKenneth Minor
Department of Neurosurgery, Anschutz Medical Campus, University of Colorado at Denver, Neurosurgery Research Laboratory, Aurora, CO 80045, USA
Neurobiol Dis 32:88-95. 2008..In addition to suppressing inhibitory scar formation, our present data shows that decorin can directly boost the ability of neurons to extend axons within CSPG or myelin rich environments...
Decorin promotes plasminogen/plasmin expression within acute spinal cord injuries and by adult microglia in vitroJeannette E Davies
Department of Neurosurgery, Baylor College of Medicine, Houston, Texas 77030, USA
J Neurotrauma 23:397-408. 2006..The wider implications of decorin induction of plasmin in the injured spinal cord for axon regeneration, and recovery of function at acute and chronic time points post-SCI are reviewed...
Changes in distribution, cell associations, and protein expression levels of NG2, neurocan, phosphacan, brevican, versican V2, and tenascin-C during acute to chronic maturation of spinal cord scar tissueXiufeng Tang
Department of Neurosurgery, Baylor College of Medicine, Houston, Texas 77030, USA
J Neurosci Res 71:427-44. 2003..Our results show novel expression patterns and cell associations of inhibitory CSPGs and tenascin-C that have important implications for axon regeneration across acute and chronic spinal cord scar tissue...
