Detail Information
Publications
Reconstructing virus structures from nanometer to near-atomic resolutions with cryo-electron microscopy and tomographyJuan Chang
Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA
Adv Exp Med Biol 726:49-90. 2012..Here we present the common techniques used to acquire and process cryo-EM and cryo-ET data and discuss their implications for structural virology both now and in the future...
Cryo-EM asymmetric reconstruction of bacteriophage P22 reveals organization of its DNA packaging and infecting machineryJuan Chang
Graduate Program in Structural and Computational Biology and Molecular Biophysics, Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas 77030, USA
Structure 14:1073-82. 2006..The coaxially packed DNA genome is encapsidated by the icosahedral shell. This complete structure unifies various biochemical, genetic, and crystallographic data of its components from the past several decades...
Structure of epsilon15 bacteriophage reveals genome organization and DNA packaging/injection apparatusWen Jiang
National Center for Macromolecular Imaging, Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas 77030, USA
Nature 439:612-6. 2006..The image reconstruction approach should be applicable to studying other biological nanomachines with components of mixed symmetries...
