Ariel Brautbar

Summary

Affiliation: Baylor College of Medicine
Country: USA

Publications

  1. pmc Rare APOA5 promoter variants associated with paradoxical HDL cholesterol decrease in response to fenofibric acid therapy
    Ariel Brautbar
    Center for Human Genetics, Marshfield Clinic Research Foundation, Marshfield, WI, USA
    J Lipid Res 54:1980-7. 2013
  2. pmc LPL gene variants affect apoC-III response to combination therapy of statins and fenofibric acid in a randomized clinical trial of individuals with mixed dyslipidemia
    Ariel Brautbar
    Department of Medical Genetics, Marshfield Clinic, Marshfield, WI, USA
    J Lipid Res 53:556-60. 2012
  3. doi request reprint Variants in the APOA5 gene region and the response to combination therapy with statins and fenofibric acid in a randomized clinical trial of individuals with mixed dyslipidemia
    Ariel Brautbar
    Section of Cardiovascular Research, Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA
    Atherosclerosis 219:737-42. 2011
  4. pmc Chromosome 9p21 single nucleotide polymorphisms are not associated with recurrent myocardial infarction in patients with established coronary artery disease
    Salim S Virani
    Center of Excellence, Health Services Research and Development, Michael E DeBakey Veterans Affairs Medical Center, Houston, TX 77030, USA
    Circ J 76:950-6. 2012
  5. pmc Single nucleotide polymorphisms in cholesteryl ester transfer protein gene and recurrent coronary heart disease or mortality in patients with established atherosclerosis
    Salim S Virani
    Health Services Research and Development Center of Excellence, Michael E DeBakey Veterans Affairs Medical Center, Houston, Texas Section of Cardiovascular Research, Department of Internal Medicine, Baylor College of Medicine, Houston, Texas Electronic address
    Am J Cardiol 112:1287-92. 2013
  6. pmc A genetic risk score based on direct associations with coronary heart disease improves coronary heart disease risk prediction in the Atherosclerosis Risk in Communities (ARIC), but not in the Rotterdam and Framingham Offspring, Studies
    Ariel Brautbar
    Department of Medical Genetics, Marshfield Clinic, Marshfield, WI, USA
    Atherosclerosis 223:421-6. 2012
  7. pmc The 9p21 genetic variant is additive to carotid intima media thickness and plaque in improving coronary heart disease risk prediction in white participants of the Atherosclerosis Risk in Communities (ARIC) Study
    Vijay Nambi
    Section of Atherosclerosis and Vascular Medicine, Department of Medicine, Baylor College of Medicine, Methodist DeBakey Heart and Vascular Center, The Methodist Hospital, Houston, TX, USA
    Atherosclerosis 222:135-7. 2012
  8. pmc Association of genome-wide variation with highly sensitive cardiac troponin-T levels in European Americans and Blacks: a meta-analysis from atherosclerosis risk in communities and cardiovascular health studies
    Bing Yu
    Human Genetic Center, University of Texas Health Science Center at Houston, Houston, TX, USA
    Circ Cardiovasc Genet 6:82-8. 2013
  9. doi request reprint A novel mutation in the ABCA1 gene causing an atypical phenotype of Tangier disease
    Smita I Negi
    Center for Atherosclerosis and Lipoprotein Research, Baylor College of Medicine, Houston, TX 77030, USA
    J Clin Lipidol 7:82-7. 2013
  10. pmc Associations between lipoprotein(a) levels and cardiovascular outcomes in black and white subjects: the Atherosclerosis Risk in Communities (ARIC) Study
    Salim S Virani
    Michael E DeBakey Veterans Affairs Medical Center Health Services Research and Development Center of Excellence, Houston, TX, USA
    Circulation 125:241-9. 2012

Detail Information

Publications14

  1. pmc Rare APOA5 promoter variants associated with paradoxical HDL cholesterol decrease in response to fenofibric acid therapy
    Ariel Brautbar
    Center for Human Genetics, Marshfield Clinic Research Foundation, Marshfield, WI, USA
    J Lipid Res 54:1980-7. 2013
    ..Further study is needed to examine the effect of these rare variants on coronary outcomes in this population in response to fenofibric acid monotherapy or combined with statins...
  2. pmc LPL gene variants affect apoC-III response to combination therapy of statins and fenofibric acid in a randomized clinical trial of individuals with mixed dyslipidemia
    Ariel Brautbar
    Department of Medical Genetics, Marshfield Clinic, Marshfield, WI, USA
    J Lipid Res 53:556-60. 2012
    ..This is the first report to show that genetic variation within the LPL gene region can affect the response of apoC-III levels to combined statin and FA therapy...
  3. doi request reprint Variants in the APOA5 gene region and the response to combination therapy with statins and fenofibric acid in a randomized clinical trial of individuals with mixed dyslipidemia
    Ariel Brautbar
    Section of Cardiovascular Research, Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA
    Atherosclerosis 219:737-42. 2011
    ..We sought to identify single nucleotide polymorphisms (SNPs) associated with HDL-C, TG, and apolipoprotein A1 (ApoA-I) response to combination therapy with statins and fenofibric acid (FA) in individuals with atherogenic dyslipidemia...
  4. pmc Chromosome 9p21 single nucleotide polymorphisms are not associated with recurrent myocardial infarction in patients with established coronary artery disease
    Salim S Virani
    Center of Excellence, Health Services Research and Development, Michael E DeBakey Veterans Affairs Medical Center, Houston, TX 77030, USA
    Circ J 76:950-6. 2012
    ....
  5. pmc Single nucleotide polymorphisms in cholesteryl ester transfer protein gene and recurrent coronary heart disease or mortality in patients with established atherosclerosis
    Salim S Virani
    Health Services Research and Development Center of Excellence, Michael E DeBakey Veterans Affairs Medical Center, Houston, Texas Section of Cardiovascular Research, Department of Internal Medicine, Baylor College of Medicine, Houston, Texas Electronic address
    Am J Cardiol 112:1287-92. 2013
    ..In conclusion, genetic CETP variants were not associated with recurrent MI or recurrent revascularization in overall cohort with a possible mortality increase in patients who underwent CABG. ..
  6. pmc A genetic risk score based on direct associations with coronary heart disease improves coronary heart disease risk prediction in the Atherosclerosis Risk in Communities (ARIC), but not in the Rotterdam and Framingham Offspring, Studies
    Ariel Brautbar
    Department of Medical Genetics, Marshfield Clinic, Marshfield, WI, USA
    Atherosclerosis 223:421-6. 2012
    ..We examined whether SNPs selected based on predefined criteria will improve CHD risk prediction when added to traditional risk factors (TRFs)...
  7. pmc The 9p21 genetic variant is additive to carotid intima media thickness and plaque in improving coronary heart disease risk prediction in white participants of the Atherosclerosis Risk in Communities (ARIC) Study
    Vijay Nambi
    Section of Atherosclerosis and Vascular Medicine, Department of Medicine, Baylor College of Medicine, Methodist DeBakey Heart and Vascular Center, The Methodist Hospital, Houston, TX, USA
    Atherosclerosis 222:135-7. 2012
    ..We evaluated whether the addition of carotid intima media thickness and plaque (CIMT-P), and a single nucleotide polymorphism on chromosome 9p21 (9p21) together improve coronary heart disease (CHD) risk prediction in the ARIC study...
  8. pmc Association of genome-wide variation with highly sensitive cardiac troponin-T levels in European Americans and Blacks: a meta-analysis from atherosclerosis risk in communities and cardiovascular health studies
    Bing Yu
    Human Genetic Center, University of Texas Health Science Center at Houston, Houston, TX, USA
    Circ Cardiovasc Genet 6:82-8. 2013
    ..To date, no large-scale genome-wide association study of hs-cTnT has been reported. We sought to identify novel genetic variants that are associated with hs-cTnT levels...
  9. doi request reprint A novel mutation in the ABCA1 gene causing an atypical phenotype of Tangier disease
    Smita I Negi
    Center for Atherosclerosis and Lipoprotein Research, Baylor College of Medicine, Houston, TX 77030, USA
    J Clin Lipidol 7:82-7. 2013
    ....
  10. pmc Associations between lipoprotein(a) levels and cardiovascular outcomes in black and white subjects: the Atherosclerosis Risk in Communities (ARIC) Study
    Salim S Virani
    Michael E DeBakey Veterans Affairs Medical Center Health Services Research and Development Center of Excellence, Houston, TX, USA
    Circulation 125:241-9. 2012
    ..We evaluated associations between Lp(a) and incident CVD events in blacks and whites in the Atherosclerosis Risk in Communities (ARIC) study...
  11. pmc Usefulness of single nucleotide polymorphism in chromosome 4q25 to predict in-hospital and long-term development of atrial fibrillation and survival in patients undergoing coronary artery bypass grafting
    Salim S Virani
    Michael E DeBakey Veterans Affairs Medical Center Health Services Research and Development Center of Excellence, Houston, Texas, USA
    Am J Cardiol 107:1504-9. 2011
    ....
  12. doi request reprint Pharmacological strategies for lowering LDL cholesterol: statins and beyond
    Ariel Brautbar
    Section of Cardiovascular Research, Department of Medicine, Baylor College of Medicine, Methodist DeBakey Heart and Vascular Center, 6565 Fannin, M S A 601, Houston, TX 77030, USA
    Nat Rev Cardiol 8:253-65. 2011
    ..These agents could be particularly appropriate for patients with severely elevated LDL-C levels, such as those with genetic dyslipidemia, for whom maximal drug therapy is insufficient to reduce LDL-C concentrations to recommended levels...
  13. pmc Impact of adding a single allele in the 9p21 locus to traditional risk factors on reclassification of coronary heart disease risk and implications for lipid-modifying therapy in the Atherosclerosis Risk in Communities study
    Ariel Brautbar
    Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA
    Circ Cardiovasc Genet 2:279-85. 2009
    ....
  14. pmc FBN1 mutations in patients with descending thoracic aortic dissections
    Ariel Brautbar
    Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA
    Am J Med Genet A 152:413-6. 2010
    ....