Research Topics
| Richard A BrainSummaryAffiliation: Baylor University Country: USA Publications
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Detail Information
Publications
Herbicidal effects of sulfamethoxazole in Lemna gibba: using p-aminobenzoic acid as a biomarker of effectRichard A Brain
Center for Reservoir and Aquatic Systems Research, Department of Environmental Science, Baylor University, Waco, Texas 76798, USA
Environ Sci Technol 42:8965-70. 2008..Using the EC50 for pABA content, a potential hazard was identified for L. gibba exposed to SMX, which would not have been detected based upon traditional standardized morphological approaches...
Biomarkers in aquatic plants: selection and utilityRichard A Brain
Center for Reservoir and Aquatic Systems Research, Department of Environmental Science, Baylor University, Waco, Texas 76798, USA
Rev Environ Contam Toxicol 198:49-109. 2009..Only through the concomitant measurement of a suite of appropriate biomarkers will our diagnostic capacity be enhanced and the field of ecotoxicology, as it relates to aquatic plants, advanced...
A protocol for conducting 7-day daily renewal tests with Lemna gibbaRichard A Brain
Department of Environmental Studies, Center for Reservoir and Aquatic Systems Research, Baylor University, One Bear Place 97388, Waco, Texas 76798 7388, USA
Nat Protoc 2:979-87. 2007..gibba. This protocol is based on a modified version of a widely accepted static method...
Influence of nitrogen and phosphorus concentrations and ratios on Lemna gibba growth responses to triclosan in laboratory and stream mesocosm experimentsBarry A Fulton
Department of Environmental Science, Baylor University, Waco, TX 76798, USA
Environ Toxicol Chem 28:2610-21. 2009..Findings from these laboratory and field studies indicate that site-specific nutrient concentrations and ratios should be considered during assessments of primary producer responses to chemical stressors...
Probabilistic ecological hazard assessment of parabens using Daphnia magna and Pimephales promelasLaura L Dobbins
Department of Environmental Science, Center for Reservoir and Aquatic Systems Research, Baylor University, Waco, TX 76798, USA
Environ Toxicol Chem 28:2744-53. 2009..The distributions demonstrated that at environmentally relevant concentrations in developed countries there is limited acute or subchronic aquatic hazard of parabens to the organisms and responses examined...
Comparison of the hazards posed to amphibians by the glyphosate spray control program versus the chemical and physical activities of coca production in ColombiaRichard A Brain
Department of Environmental Studies, Baylor University, Waco, Texas 76798 7388, USA
J Toxicol Environ Health A 72:937-48. 2009....
Occurrence of pharmaceuticals and personal care products in fish: results of a national pilot study in the United StatesAlejandro J Ramirez
Department of Chemistry and Biochemistry, Center for Reservoir and Aquatic Systems Research, Baylor University, Waco, TX 76798, USA
Environ Toxicol Chem 28:2587-97. 2009..Results suggest that the detection of pharmaceuticals and personal care products was dependent on the degree of wastewater treatment employed...
Exploring Lemna gibba thresholds to nutrient and chemical stressors: differential effects of triclosan on internal stoichiometry and nitrate uptake across a nitrogen:phosphorus gradientBarry A Fulton
Department of Environmental Science, Baylor University, Waco, Texas, USA
Environ Toxicol Chem 29:2363-70. 2010..Future studies should examine adverse effects of other stressors to these ecologically relevant endpoints, which may be useful in environmental assessment and management...
Comparison of the sensitivities of common in vitro and in vivo assays of estrogenic activity: application of chemical toxicity distributionsLaura L Dobbins
Department of Environmental Science, Institute of Biomedical Studies, Center for Reservoir and Aquatic Systems Research, Baylor University, One Bear Place No 97266, Waco, Texas 76798, USA
Environ Toxicol Chem 27:2608-16. 2008..Subsequently, CTDs may provide a useful technique for hazard assessment of chemical classes for which exposure data are limited and for chemicals with common toxicological mechanisms and modes of action...
Aquatic plants exposed to pharmaceuticals: effects and risksRichard A Brain
Center for Reservoir and Aquatic Systems Research, Department of Environmental Studies, Baylor University, One Bear Place, Waco, TX 76798 7388, USA
Rev Environ Contam Toxicol 192:67-115. 2008....
Probabilistic ecological hazard assessment: evaluating pharmaceutical effects on aquatic higher plants as an exampleRichard A Brain
Centre for Toxicology and Department of Environmental Biology, University of Guelph, Guelph, Ont, Canada N1G 2W1
Ecotoxicol Environ Saf 64:128-35. 2006..gibba (8PM data). Hazard quotients calculated from the 1% and 5% distribution thresholds indicated potential risk only in certain cases...
Microcosm evaluation of the fate, toxicity, and risk to aquatic macrophytes from perfluorooctanoic acid (PFOA)Mark L Hanson
Centre for Toxicology, Department of Environmental Biology, University of Guelph, Guelph, Ontario, N1G 2W1, Canada
Arch Environ Contam Toxicol 49:307-16. 2005..were consistently > or = 23.9 mg/L PFOA. A risk assessment for these plant species estimated a negligible probability of toxicity being observed from PFOA exposure at current environmental concentrations...
Effects of a mixture of tetracyclines to Lemna gibba and Myriophyllum sibiricum evaluated in aquatic microcosmsRichard A Brain
Centre for Toxicology, Department of Environmental Biology, University of Guelph, Guelph, Ontario, Canada N1G 2W1
Environ Pollut 138:425-42. 2005..gibba) and submerged (M. sibiricum) species of macrophytes. A hazard quotient assessment of the lowest EC10 value indicated significant risk, exceeding the critical HQ value, but not the lowest EC25 value...
Aquatic microcosm assessment of the effects of tylosin on Lemna gibba and Myriophyllum spicatumRichard A Brain
Centre for Toxicology, Department of Environmental Biology, University of Guelph, Guelph, ON, Canada N1G 2W1
Environ Pollut 133:389-401. 2005..spicatum or L. gibba. A hazard quotient assessment indicated that tylosin poses little risk to either species of macrophyte, with an HQ value calculated to be nearly three orders of magnitude below 1 (0.002)...
Microcosm evaluation of the effects of an eight pharmaceutical mixture to the aquatic macrophytes Lemna gibba and Myriophyllum sibiricumRichard A Brain
Department of Environmental Biology, Centre for Toxicology, University of Guelph, Guelph, Ont, N1G 2W1, Canada
Aquat Toxicol 70:23-40. 2004..sibiricum exposed to similar mixtures of pharmaceutical compounds. For M. sibiricum and L. gibba, respective minimum differences of 5 and 1%, were detectable, however, these effect sizes are not considered ecologically significant...
Ranking and prioritization of environmental risks of pharmaceuticals in surface watersHans Sanderson
Centre for Toxicology, University of Guelph, Bovey Building, Guelph, Ont, Canada N1G 2W1
Regul Toxicol Pharmacol 39:158-83. 2004..Data available: http://www.uoguelph.ca/~hsander/...
Effects of 25 pharmaceutical compounds to Lemna gibba using a seven-day static-renewal testRichard A Brain
Centre for Toxicology, Department of Environmental Biology, Bovey Administrative Building, University of Guelph, Guelph, Ontario N1G 2W1, Canada
Environ Toxicol Chem 23:371-82. 2004..Wet mass was consistently the most sensitive endpoint above 100 microg/L; conversely, frond number was the most sensitive below 100 microg/L. Pigment endpoints were significantly less sensitive than growth endpoints...
Probabilistic hazard assessment of environmentally occurring pharmaceuticals toxicity to fish, daphnids and algae by ECOSAR screeningHans Sanderson
Center for Toxicology, University of Guelph, Bovey Building, Gordon Street, Guelph, Ont, Canada N1G 2W1
Toxicol Lett 144:383-95. 2003..are still uncertain. (Q)SAR's can be important prioritization tools for subsequent experimental risk assessment of pharmaceuticals in surface waters, due to the prevalent lack of ecotoxicological data...
