Richard A Brain

Summary

Affiliation: Baylor University
Country: USA

Publications

  1. ncbi request reprint Herbicidal effects of sulfamethoxazole in Lemna gibba: using p-aminobenzoic acid as a biomarker of effect
    Richard A Brain
    Center for Reservoir and Aquatic Systems Research, Department of Environmental Science, Baylor University, Waco, Texas 76798, USA
    Environ Sci Technol 42:8965-70. 2008
  2. doi request reprint Biomarkers in aquatic plants: selection and utility
    Richard A Brain
    Center for Reservoir and Aquatic Systems Research, Department of Environmental Science, Baylor University, Waco, Texas 76798, USA
    Rev Environ Contam Toxicol 198:49-109. 2009
  3. ncbi request reprint A protocol for conducting 7-day daily renewal tests with Lemna gibba
    Richard A Brain
    Department of Environmental Studies, Center for Reservoir and Aquatic Systems Research, Baylor University, One Bear Place 97388, Waco, Texas 76798 7388, USA
    Nat Protoc 2:979-87. 2007
  4. doi request reprint Influence of nitrogen and phosphorus concentrations and ratios on Lemna gibba growth responses to triclosan in laboratory and stream mesocosm experiments
    Barry A Fulton
    Department of Environmental Science, Baylor University, Waco, TX 76798, USA
    Environ Toxicol Chem 28:2610-21. 2009
  5. doi request reprint Probabilistic ecological hazard assessment of parabens using Daphnia magna and Pimephales promelas
    Laura L Dobbins
    Department of Environmental Science, Center for Reservoir and Aquatic Systems Research, Baylor University, Waco, TX 76798, USA
    Environ Toxicol Chem 28:2744-53. 2009
  6. doi request reprint Comparison of the hazards posed to amphibians by the glyphosate spray control program versus the chemical and physical activities of coca production in Colombia
    Richard A Brain
    Department of Environmental Studies, Baylor University, Waco, Texas 76798 7388, USA
    J Toxicol Environ Health A 72:937-48. 2009
  7. doi request reprint Occurrence of pharmaceuticals and personal care products in fish: results of a national pilot study in the United States
    Alejandro J Ramirez
    Department of Chemistry and Biochemistry, Center for Reservoir and Aquatic Systems Research, Baylor University, Waco, TX 76798, USA
    Environ Toxicol Chem 28:2587-97. 2009
  8. doi request reprint Exploring Lemna gibba thresholds to nutrient and chemical stressors: differential effects of triclosan on internal stoichiometry and nitrate uptake across a nitrogen:phosphorus gradient
    Barry A Fulton
    Department of Environmental Science, Baylor University, Waco, Texas, USA
    Environ Toxicol Chem 29:2363-70. 2010
  9. doi request reprint Comparison of the sensitivities of common in vitro and in vivo assays of estrogenic activity: application of chemical toxicity distributions
    Laura L Dobbins
    Department of Environmental Science, Institute of Biomedical Studies, Center for Reservoir and Aquatic Systems Research, Baylor University, One Bear Place No 97266, Waco, Texas 76798, USA
    Environ Toxicol Chem 27:2608-16. 2008
  10. ncbi request reprint Aquatic plants exposed to pharmaceuticals: effects and risks
    Richard A Brain
    Center for Reservoir and Aquatic Systems Research, Department of Environmental Studies, Baylor University, One Bear Place, Waco, TX 76798 7388, USA
    Rev Environ Contam Toxicol 192:67-115. 2008

Collaborators

Detail Information

Publications18

  1. ncbi request reprint Herbicidal effects of sulfamethoxazole in Lemna gibba: using p-aminobenzoic acid as a biomarker of effect
    Richard A Brain
    Center for Reservoir and Aquatic Systems Research, Department of Environmental Science, Baylor University, Waco, Texas 76798, USA
    Environ Sci Technol 42:8965-70. 2008
    ..Using the EC50 for pABA content, a potential hazard was identified for L. gibba exposed to SMX, which would not have been detected based upon traditional standardized morphological approaches...
  2. doi request reprint Biomarkers in aquatic plants: selection and utility
    Richard A Brain
    Center for Reservoir and Aquatic Systems Research, Department of Environmental Science, Baylor University, Waco, Texas 76798, USA
    Rev Environ Contam Toxicol 198:49-109. 2009
    ..Only through the concomitant measurement of a suite of appropriate biomarkers will our diagnostic capacity be enhanced and the field of ecotoxicology, as it relates to aquatic plants, advanced...
  3. ncbi request reprint A protocol for conducting 7-day daily renewal tests with Lemna gibba
    Richard A Brain
    Department of Environmental Studies, Center for Reservoir and Aquatic Systems Research, Baylor University, One Bear Place 97388, Waco, Texas 76798 7388, USA
    Nat Protoc 2:979-87. 2007
    ..gibba. This protocol is based on a modified version of a widely accepted static method...
  4. doi request reprint Influence of nitrogen and phosphorus concentrations and ratios on Lemna gibba growth responses to triclosan in laboratory and stream mesocosm experiments
    Barry A Fulton
    Department of Environmental Science, Baylor University, Waco, TX 76798, USA
    Environ Toxicol Chem 28:2610-21. 2009
    ..Findings from these laboratory and field studies indicate that site-specific nutrient concentrations and ratios should be considered during assessments of primary producer responses to chemical stressors...
  5. doi request reprint Probabilistic ecological hazard assessment of parabens using Daphnia magna and Pimephales promelas
    Laura L Dobbins
    Department of Environmental Science, Center for Reservoir and Aquatic Systems Research, Baylor University, Waco, TX 76798, USA
    Environ Toxicol Chem 28:2744-53. 2009
    ..The distributions demonstrated that at environmentally relevant concentrations in developed countries there is limited acute or subchronic aquatic hazard of parabens to the organisms and responses examined...
  6. doi request reprint Comparison of the hazards posed to amphibians by the glyphosate spray control program versus the chemical and physical activities of coca production in Colombia
    Richard A Brain
    Department of Environmental Studies, Baylor University, Waco, Texas 76798 7388, USA
    J Toxicol Environ Health A 72:937-48. 2009
    ....
  7. doi request reprint Occurrence of pharmaceuticals and personal care products in fish: results of a national pilot study in the United States
    Alejandro J Ramirez
    Department of Chemistry and Biochemistry, Center for Reservoir and Aquatic Systems Research, Baylor University, Waco, TX 76798, USA
    Environ Toxicol Chem 28:2587-97. 2009
    ..Results suggest that the detection of pharmaceuticals and personal care products was dependent on the degree of wastewater treatment employed...
  8. doi request reprint Exploring Lemna gibba thresholds to nutrient and chemical stressors: differential effects of triclosan on internal stoichiometry and nitrate uptake across a nitrogen:phosphorus gradient
    Barry A Fulton
    Department of Environmental Science, Baylor University, Waco, Texas, USA
    Environ Toxicol Chem 29:2363-70. 2010
    ..Future studies should examine adverse effects of other stressors to these ecologically relevant endpoints, which may be useful in environmental assessment and management...
  9. doi request reprint Comparison of the sensitivities of common in vitro and in vivo assays of estrogenic activity: application of chemical toxicity distributions
    Laura L Dobbins
    Department of Environmental Science, Institute of Biomedical Studies, Center for Reservoir and Aquatic Systems Research, Baylor University, One Bear Place No 97266, Waco, Texas 76798, USA
    Environ Toxicol Chem 27:2608-16. 2008
    ..Subsequently, CTDs may provide a useful technique for hazard assessment of chemical classes for which exposure data are limited and for chemicals with common toxicological mechanisms and modes of action...
  10. ncbi request reprint Aquatic plants exposed to pharmaceuticals: effects and risks
    Richard A Brain
    Center for Reservoir and Aquatic Systems Research, Department of Environmental Studies, Baylor University, One Bear Place, Waco, TX 76798 7388, USA
    Rev Environ Contam Toxicol 192:67-115. 2008
    ....
  11. ncbi request reprint Probabilistic ecological hazard assessment: evaluating pharmaceutical effects on aquatic higher plants as an example
    Richard A Brain
    Centre for Toxicology and Department of Environmental Biology, University of Guelph, Guelph, Ont, Canada N1G 2W1
    Ecotoxicol Environ Saf 64:128-35. 2006
    ..gibba (8PM data). Hazard quotients calculated from the 1% and 5% distribution thresholds indicated potential risk only in certain cases...
  12. ncbi request reprint Microcosm evaluation of the fate, toxicity, and risk to aquatic macrophytes from perfluorooctanoic acid (PFOA)
    Mark L Hanson
    Centre for Toxicology, Department of Environmental Biology, University of Guelph, Guelph, Ontario, N1G 2W1, Canada
    Arch Environ Contam Toxicol 49:307-16. 2005
    ..were consistently > or = 23.9 mg/L PFOA. A risk assessment for these plant species estimated a negligible probability of toxicity being observed from PFOA exposure at current environmental concentrations...
  13. ncbi request reprint Effects of a mixture of tetracyclines to Lemna gibba and Myriophyllum sibiricum evaluated in aquatic microcosms
    Richard A Brain
    Centre for Toxicology, Department of Environmental Biology, University of Guelph, Guelph, Ontario, Canada N1G 2W1
    Environ Pollut 138:425-42. 2005
    ..gibba) and submerged (M. sibiricum) species of macrophytes. A hazard quotient assessment of the lowest EC10 value indicated significant risk, exceeding the critical HQ value, but not the lowest EC25 value...
  14. ncbi request reprint Aquatic microcosm assessment of the effects of tylosin on Lemna gibba and Myriophyllum spicatum
    Richard A Brain
    Centre for Toxicology, Department of Environmental Biology, University of Guelph, Guelph, ON, Canada N1G 2W1
    Environ Pollut 133:389-401. 2005
    ..spicatum or L. gibba. A hazard quotient assessment indicated that tylosin poses little risk to either species of macrophyte, with an HQ value calculated to be nearly three orders of magnitude below 1 (0.002)...
  15. ncbi request reprint Microcosm evaluation of the effects of an eight pharmaceutical mixture to the aquatic macrophytes Lemna gibba and Myriophyllum sibiricum
    Richard A Brain
    Department of Environmental Biology, Centre for Toxicology, University of Guelph, Guelph, Ont, N1G 2W1, Canada
    Aquat Toxicol 70:23-40. 2004
    ..sibiricum exposed to similar mixtures of pharmaceutical compounds. For M. sibiricum and L. gibba, respective minimum differences of 5 and 1%, were detectable, however, these effect sizes are not considered ecologically significant...
  16. ncbi request reprint Ranking and prioritization of environmental risks of pharmaceuticals in surface waters
    Hans Sanderson
    Centre for Toxicology, University of Guelph, Bovey Building, Guelph, Ont, Canada N1G 2W1
    Regul Toxicol Pharmacol 39:158-83. 2004
    ..Data available: http://www.uoguelph.ca/~hsander/...
  17. ncbi request reprint Effects of 25 pharmaceutical compounds to Lemna gibba using a seven-day static-renewal test
    Richard A Brain
    Centre for Toxicology, Department of Environmental Biology, Bovey Administrative Building, University of Guelph, Guelph, Ontario N1G 2W1, Canada
    Environ Toxicol Chem 23:371-82. 2004
    ..Wet mass was consistently the most sensitive endpoint above 100 microg/L; conversely, frond number was the most sensitive below 100 microg/L. Pigment endpoints were significantly less sensitive than growth endpoints...
  18. ncbi request reprint Probabilistic hazard assessment of environmentally occurring pharmaceuticals toxicity to fish, daphnids and algae by ECOSAR screening
    Hans Sanderson
    Center for Toxicology, University of Guelph, Bovey Building, Gordon Street, Guelph, Ont, Canada N1G 2W1
    Toxicol Lett 144:383-95. 2003
    ..are still uncertain. (Q)SAR's can be important prioritization tools for subsequent experimental risk assessment of pharmaceuticals in surface waters, due to the prevalent lack of ecotoxicological data...