Penelope E Bonnen

Summary

Affiliation: Baylor College of Medicine
Country: USA

Publications

  1. pmc Mutations in FBXL4 cause mitochondrial encephalopathy and a disorder of mitochondrial DNA maintenance
    Penelope E Bonnen
    Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA
    Am J Hum Genet 93:471-81. 2013
  2. pmc European admixture on the Micronesian island of Kosrae: lessons from complete genetic information
    Penelope E Bonnen
    Department of Human and Molecular Genetics, Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030, USA
    Eur J Hum Genet 18:309-16. 2010
  3. doi request reprint Longitudinal study shows increasing obesity and hyperglycemia in micronesia
    David Murdock
    Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, USA Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas, USA
    Obesity (Silver Spring) 21:E421-7. 2013
  4. pmc Haplotype and linkage disequilibrium architecture for human cancer-associated genes
    Penelope E Bonnen
    Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA
    Genome Res 12:1846-53. 2002
  5. pmc Exome sequencing of a patient with suspected mitochondrial disease reveals a likely multigenic etiology
    William J Craigen
    Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA
    BMC Med Genet 14:83. 2013
  6. doi request reprint WDR35 mutation in siblings with Sensenbrenner syndrome: a ciliopathy with variable phenotype
    Carlos A Bacino
    Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA
    Am J Med Genet A 158:2917-24. 2012
  7. pmc TM4SF20 ancestral deletion and susceptibility to a pediatric disorder of early language delay and cerebral white matter hyperintensities
    Wojciech Wiszniewski
    Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA
    Am J Hum Genet 93:197-210. 2013
  8. doi request reprint WDR62 missense mutation in a consanguineous family with primary microcephaly
    Carlos A Bacino
    Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, USA
    Am J Med Genet A 158:622-5. 2012

Collaborators

Detail Information

Publications8

  1. pmc Mutations in FBXL4 cause mitochondrial encephalopathy and a disorder of mitochondrial DNA maintenance
    Penelope E Bonnen
    Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA
    Am J Hum Genet 93:471-81. 2013
    ..Together our data demonstrate that mutations in FBXL4 are disease causing and establish FBXL4 as a mitochondrial protein with a possible role in maintaining mtDNA integrity and stability. ..
  2. pmc European admixture on the Micronesian island of Kosrae: lessons from complete genetic information
    Penelope E Bonnen
    Department of Human and Molecular Genetics, Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030, USA
    Eur J Hum Genet 18:309-16. 2010
    ..This approach shows the benefit of combining information from autosomal and uniparental polymorphisms and provides new methodology for determining ancestry in a population...
  3. doi request reprint Longitudinal study shows increasing obesity and hyperglycemia in micronesia
    David Murdock
    Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, USA Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas, USA
    Obesity (Silver Spring) 21:E421-7. 2013
    ..The prevalence of obesity, diabetes, hyperglycemia, dyslipidemia, and hypertension in one such population, the Micronesian island of Kosrae was described...
  4. pmc Haplotype and linkage disequilibrium architecture for human cancer-associated genes
    Penelope E Bonnen
    Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA
    Genome Res 12:1846-53. 2002
    ..As a result, a low marker density should be adequate to identify haplotypes that represent the common variation at a locus, thereby decreasing costs and increasing efficacy of association studies...
  5. pmc Exome sequencing of a patient with suspected mitochondrial disease reveals a likely multigenic etiology
    William J Craigen
    Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA
    BMC Med Genet 14:83. 2013
    ....
  6. doi request reprint WDR35 mutation in siblings with Sensenbrenner syndrome: a ciliopathy with variable phenotype
    Carlos A Bacino
    Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA
    Am J Med Genet A 158:2917-24. 2012
    ..Detailed genotype-phenotype information is provided as well as discussion of previously reported cases...
  7. pmc TM4SF20 ancestral deletion and susceptibility to a pediatric disorder of early language delay and cerebral white matter hyperintensities
    Wojciech Wiszniewski
    Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA
    Am J Hum Genet 93:197-210. 2013
    ....
  8. doi request reprint WDR62 missense mutation in a consanguineous family with primary microcephaly
    Carlos A Bacino
    Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, USA
    Am J Med Genet A 158:622-5. 2012
    ..Studies of ASPM and WDR62 should perhaps be pursued in all cases of primary microcephaly with or without gross brain malformations...