Alison A Bertuch

Summary

Affiliation: Baylor College of Medicine
Country: USA

Publications

  1. ncbi Ku must load directly onto the chromosome end in order to mediate its telomeric functions
    Christopher R Lopez
    Department of Pediatrics, Baylor College of Medicine, Houston, Texas, United States of America
    PLoS Genet 7:e1002233. 2011
  2. ncbi Distinct faces of the Ku heterodimer mediate DNA repair and telomeric functions
    Albert Ribes-Zamora
    Department of Pediatrics, Hematology Oncology Section, Baylor College of Medicine, One Baylor Plaza, BCM225, Houston, Texas 77030 3411, USA
    Nat Struct Mol Biol 14:301-7. 2007
  3. ncbi The Ku heterodimer performs separable activities at double-strand breaks and chromosome termini
    Alison A Bertuch
    Department of Pediatrics, Hematology Oncology Section, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA
    Mol Cell Biol 23:8202-15. 2003
  4. ncbi EXO1 contributes to telomere maintenance in both telomerase-proficient and telomerase-deficient Saccharomyces cerevisiae
    Alison A Bertuch
    Department of Molecular and Human Genetics, Hematology Oncology Section, Baylor College of Medicine, Houston, Texas 77030, USA
    Genetics 166:1651-9. 2004
  5. ncbi Abdominal undifferentiated small round cell tumor with unique translocation (X;19)(q13;q13.3)
    Jason T Yustein
    Department of Pediatrics, Texas Children s Cancer Center, Baylor College of Medicine, Houston, Texas, USA
    Pediatr Blood Cancer 54:1041-4. 2010
  6. ncbi Dyskeratosis congenita as a disorder of telomere maintenance
    Nya D Nelson
    Department of Molecular and Human Genetics, Texas Children s Hospital, Houston, TX 77030, USA
    Mutat Res 730:43-51. 2012
  7. ncbi Which end: dissecting Ku's function at telomeres and double-strand breaks
    Alison A Bertuch
    Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA
    Genes Dev 17:2347-50. 2003
  8. ncbi The maintenance and masking of chromosome termini
    Alison A Bertuch
    Department of Pediatrics, Hematology/Oncology Section, Baylor College of Medicine, Houston, TX 77030, USA
    Curr Opin Cell Biol 18:247-53. 2006
  9. ncbi The way to the end matters--the role of telomerase in tumor progression
    Alison A Bertuch
    Department of Molecular and Human Genetics, Hematology/Oncology Section, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA
    Cell Cycle 2:36-8. 2003

Collaborators

Detail Information

Publications9

  1. ncbi Ku must load directly onto the chromosome end in order to mediate its telomeric functions
    Christopher R Lopez
    Department of Pediatrics, Baylor College of Medicine, Houston, Texas, United States of America
    PLoS Genet 7:e1002233. 2011
    ..The extensive telomere defects observed in these mutants lead us to propose that Ku is an integral component of the terminal telomeric cap, where it promotes a specific architecture that is central to telomere function and maintenance...
  2. ncbi Distinct faces of the Ku heterodimer mediate DNA repair and telomeric functions
    Albert Ribes-Zamora
    Department of Pediatrics, Hematology Oncology Section, Baylor College of Medicine, One Baylor Plaza, BCM225, Houston, Texas 77030 3411, USA
    Nat Struct Mol Biol 14:301-7. 2007
    ..We propose a 'two-face' model for Ku and that divergent evolution of these faces allowed Ku's dual role in NHEJ and telomere maintenance...
  3. ncbi The Ku heterodimer performs separable activities at double-strand breaks and chromosome termini
    Alison A Bertuch
    Department of Pediatrics, Hematology Oncology Section, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA
    Mol Cell Biol 23:8202-15. 2003
    ....
  4. ncbi EXO1 contributes to telomere maintenance in both telomerase-proficient and telomerase-deficient Saccharomyces cerevisiae
    Alison A Bertuch
    Department of Molecular and Human Genetics, Hematology Oncology Section, Baylor College of Medicine, Houston, Texas 77030, USA
    Genetics 166:1651-9. 2004
    ..These data demonstrate that Exo1 can make either positive or negative contributions to telomere function and cell viability, depending on whether telomerase or recombination is utilized to maintain telomere function...
  5. ncbi Abdominal undifferentiated small round cell tumor with unique translocation (X;19)(q13;q13.3)
    Jason T Yustein
    Department of Pediatrics, Texas Children s Cancer Center, Baylor College of Medicine, Houston, Texas, USA
    Pediatr Blood Cancer 54:1041-4. 2010
    ..3), which has not been reported in small round cell tumors of childhood or adults. The final diagnosis rendered was an undifferentiated small round cell tumor of uncertain cell of origin...
  6. ncbi Dyskeratosis congenita as a disorder of telomere maintenance
    Nya D Nelson
    Department of Molecular and Human Genetics, Texas Children s Hospital, Houston, TX 77030, USA
    Mutat Res 730:43-51. 2012
    ..This review will highlight our current knowledge of the telomere length defects in DC and the factors involved in its development...
  7. ncbi Which end: dissecting Ku's function at telomeres and double-strand breaks
    Alison A Bertuch
    Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA
    Genes Dev 17:2347-50. 2003
  8. ncbi The maintenance and masking of chromosome termini
    Alison A Bertuch
    Department of Pediatrics, Hematology/Oncology Section, Baylor College of Medicine, Houston, TX 77030, USA
    Curr Opin Cell Biol 18:247-53. 2006
    ....
  9. ncbi The way to the end matters--the role of telomerase in tumor progression
    Alison A Bertuch
    Department of Molecular and Human Genetics, Hematology/Oncology Section, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA
    Cell Cycle 2:36-8. 2003