Christine Beeton

Summary

Affiliation: Baylor College of Medicine
Country: USA

Publications

  1. doi request reprint Ca(2+) permeation and/or binding to CaV1.1 fine-tunes skeletal muscle Ca(2+) signaling to sustain muscle function
    Chang Seok Lee
    Department of Molecular Physiology and Biophysics, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030 USA
    Skelet Muscle 5:4. 2015
  2. pmc Blocking KCa3.1 channels increases tumor cell killing by a subpopulation of human natural killer lymphocytes
    Shyny Koshy
    Department of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, Texas, United States of America
    PLoS ONE 8:e76740. 2013
  3. pmc Analogs of the sea anemone potassium channel blocker ShK for the treatment of autoimmune diseases
    Christine Beeton
    Department of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, Texas 77030, USA
    Inflamm Allergy Drug Targets 10:313-21. 2011
  4. pmc KCa1.1 potassium channels regulate key proinflammatory and invasive properties of fibroblast-like synoviocytes in rheumatoid arthritis
    Xueyou Hu
    Department of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, Texas 77030, USA
    J Biol Chem 287:4014-22. 2012

Collaborators

  • Heike Wulff
  • Percio S Gulko
  • Frank T Horrigan
  • Raymond S Norton
  • Shyny Koshy
  • Xueyou Hu
  • Chang Seok Lee
  • Iskander I Ismailov
  • Patricia Yotnda
  • George G Rodney
  • Dimitra K Georgiou
  • Michael W Swank
  • Susan L Hamilton
  • Adan Dagnino-Acosta
  • Viktor Yarotskyy
  • Ross A Poche
  • Keke Dong
  • Amy Hanna
  • Alla Lyfenko
  • Mark Knoblauch
  • Ted Tran
  • Robert T Dirksen
  • Pumin Zhang
  • Mary E Dickinson
  • Johanna Lanner
  • Cheng Long
  • Rajeev B Tajhya
  • Redwan Huq
  • Michael W Pennington
  • Fatima S Khan
  • DanLi Wu
  • Teresina Laragione
  • Liang Sun
  • Karlie R Jones

Detail Information

Publications6

  1. doi request reprint Ca(2+) permeation and/or binding to CaV1.1 fine-tunes skeletal muscle Ca(2+) signaling to sustain muscle function
    Chang Seok Lee
    Department of Molecular Physiology and Biophysics, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030 USA
    Skelet Muscle 5:4. 2015
    ..1 is not required for skeletal muscle excitation-contraction coupling, but whether Ca(2+) permeation through CaV1.1 during sustained muscle activity plays a functional role in mammalian skeletal muscle has not been assessed...
  2. pmc Blocking KCa3.1 channels increases tumor cell killing by a subpopulation of human natural killer lymphocytes
    Shyny Koshy
    Department of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, Texas, United States of America
    PLoS ONE 8:e76740. 2013
    ..This results in a TRAM-34-induced increased ability of A-NK cells to reduce in vivo tumor growth. Taken together, our results suggest that targeting KCa3.1 on NK cells with selective blockers may be beneficial in cancer immunotherapy. ..
  3. pmc Analogs of the sea anemone potassium channel blocker ShK for the treatment of autoimmune diseases
    Christine Beeton
    Department of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, Texas 77030, USA
    Inflamm Allergy Drug Targets 10:313-21. 2011
    ..They are currently undergoing further evaluation as potential immunomodulators for the treatment of autoimmune diseases...
  4. pmc KCa1.1 potassium channels regulate key proinflammatory and invasive properties of fibroblast-like synoviocytes in rheumatoid arthritis
    Xueyou Hu
    Department of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, Texas 77030, USA
    J Biol Chem 287:4014-22. 2012
    ..Our findings indicate a regulatory role of KCa1.1 channels in RA-FLS function and suggest this channel as a potential target for the treatment of RA...