Research Topics
| C J BakerSummaryAffiliation: Baylor College of Medicine Country: USA Publications
| Collaborators
|
Detail Information
Publications
The frequency of genes encoding three putative group B streptococcal virulence factors among invasive and colonizing isolatesShannon D Manning
National Food Safety and Toxicology Center and Department of Pediatrics and Human Development, Michigan State University, East Lansing, Michigan, USA
BMC Infect Dis 6:116. 2006..It is not known, however, whether these genes occur more frequently in invasive versus colonizing GBS strains...- Immune response of healthy women to 2 different group B streptococcal type V capsular polysaccharide-protein conjugate vaccinesCarol J Baker
Section of Infectious Diseases, Department of Pediatrics, Baylor College of Medicine, Houston, Texas 77030, USA
J Infect Dis 189:1103-12. 2004..Infections caused by group B streptococcal (GBS) type V are increasingly common. Capsular polysaccharide (CPS)-protein conjugate GBS vaccines are immunogenic in healthy adults, but type V vaccines have not previously been tested... - Use of capsular polysaccharide-tetanus toxoid conjugate vaccine for type II group B Streptococcus in healthy womenC J Baker
Dept of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA
J Infect Dis 182:1129-38. 2000..Immunological responses to conjugate were dose dependent and correlated with opsonophagocytosis in vitro. These results support inclusion of II-TT conjugate when preparing a multivalent GBS vaccine... - Safety and immunogenicity of capsular polysaccharide-tetanus toxoid conjugate vaccines for group B streptococcal types Ia and IbC J Baker
Section of Infectious Diseases, Department of Pediatrics, Baylor College of Medicine, Houston, Texas, USA
J Infect Dis 179:142-50. 1999..Immune responses to the conjugates were dose-dependent and correlated in vitro with opsonophagocytosis. These results support inclusion of Ia- and Ib-TT conjugates when formulating a multivalent GBS vaccine... - Dose-response to type V group B streptococcal polysaccharide-tetanus toxoid conjugate vaccine in healthy adultsCarol J Baker
Section of Infectious Diseases, Department of Pediatrics, Room 302A, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, United States
Vaccine 25:55-63. 2007..V-TT vaccine-induced antibodies promoted opsonophagocytic killing of type V GBS and avidity maturation of V CPS-specific IgG... - Safety and immunogenicity of a bivalent group B streptococcal conjugate vaccine for serotypes II and IIICarol J Baker
Sections of Infectious Diseases, Department of Pediatrics, and Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA
J Infect Dis 188:66-73. 2003..These results support the feasibility of a multivalent vaccine for the 5 prevalent invasive disease-causing GBS CPS serotypes... - Immunization of pregnant women with group B streptococcal type III capsular polysaccharide-tetanus toxoid conjugate vaccineCarol J Baker
Departments of Pediatrics, Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX, USA
Vaccine 21:3468-72. 2003..To determine the safety and immunogenicity of group B streptococcal (GBS) type III CPS-TT conjugate vaccine in pregnant women... - Group B streptococcal conjugate vaccinesC J Baker
Section of Infectious Diseases, Department of Pediatrics, Baylor College of Medicine, Houston, Texas 77030, USA
Arch Dis Child 88:375-8. 2003.... - A 5-year review of recurrent group B streptococcal disease: lessons from twin infantsE H Moylett
Section of Infectious Diseases, Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA
Clin Infect Dis 30:282-7. 2000..The exact pathogenesis of recurrent GBS disease remains unclear, but our data support the hypothesis that persistent mucosal colonization with the original GBS strain rather than new acquisition is a pivotal factor in disease recurrence... - Group B streptococcal colonization and serotype-specific immunity in pregnant women at deliveryJ R Campbell
Pediatrics, Baylor College of Medicine, Houston, Texas 77030, USA
Obstet Gynecol 96:498-503. 2000..To describe the relationship between serum concentration of group B streptococcal capsular polysaccharide-specific immunoglobulin (Ig) G, colonization status, race or ethnicity, and age in pregnant women... - Failure of rifampin to eradicate group B streptococcal colonization in infantsM Fernandez
Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA
Pediatr Infect Dis J 20:371-6. 2001..CONCLUSIONS: Rifampin treatment for four days utilized as a single agent after completion of parenteral therapy failed to reliably eradicate GBS colonization in infants... - Suppurative thrombophlebitis in children: a ten-year experienceE A Khan
Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA
Pediatr Infect Dis J 16:63-7. 1997..To determine the clinical and diagnostic features, complications, management and prevention of superficial suppurative thrombophlebitis (ST) in children < 18 years of age... - Clinical and laboratory characteristics of a large cohort of symptomatic, human immunodeficiency virus-infected infants and children. AIDS Clinical Trials Group Protocol 152 Study TeamJ A Englund
Department of Microbiology and Immunology, Baylor College of Medicine, Houston, TX 77030, USA
Pediatr Infect Dis J 15:1025-36. 1996.... - Enterococcal sepsis in neonates: features by age at onset and occurrence of focal infectionS R Dobson
Myers Black Section of Infectious Diseases, Department of Pediatrics, Baylor College of Medicine, Houston, Texas 77030
Pediatrics 85:165-71. 1990..Enterococcus is a frequent cause of late-onset septicemia in premature neonates, and empiric therapy should include appropriate antimicrobial agents... - Systemic candidiasis in extremely low birth weight infants receiving topical petrolatum ointment for skin care: a case-control studyJ R Campbell
Section of Infectious Diseases, Department of Pediatrics, Baylor College of Medicine, TX 77030, USA
Pediatrics 105:1041-5. 2000..We sought to determine whether the use of topical petrolatum ointment (TPO) for skin care of ELBW infants was associated with risk for SC... - Role of neutrophil receptors in opsonophagocytosis of coagulase-negative staphylococciG E Schutze
Department of Pediatrics, Baylor College of Medicine, Houston, Texas 77030
Infect Immun 59:2573-8. 1991..The inefficiency of these interactions with neutrophils from premature infants may partially explain the enhanced susceptibility of very-low-birth-weight neonates to disseminated, coagulase-negative staphylococcal infections... - Predictive value of quantitative plasma HIV RNA and CD4+ lymphocyte count in HIV-infected infants and childrenP E Palumbo
Department of Pediatrics, University of Medicine and Dentistry of New Jersey, Newark 07103, USA
JAMA 279:756-61. 1998..Pediatric human immunodeficiency virus (HIV) infection has unique viral pathogenetic features that preclude routine extrapolation from adult studies and require specific analysis... - Ophthalmologic, visceral, and cardiac involvement in neonates with candidemiaD E Noyola
Section of Infectious Diseases, Department of Pediatrics, Houston, TX 77030, USA
Clin Infect Dis 32:1018-23. 2001.... - Virologic and immunologic response to nucleoside reverse-transcriptase inhibitor therapy among human immunodeficiency virus-infected infants and childrenP E Palumbo
Department of Pediatrics, University of Medicine and Dentistry of New Jersey, Newark, NJ 07103, USA
J Infect Dis 179:576-83. 1999..Nevertheless, plasma RNA and CD4 lymphocyte count together possess strong clinical predictive power and are valuable tools for both the clinician and the evaluation of new therapies... - Prevalence of group B streptococcus colonization and potential for transmission by casual contact in healthy young men and womenShannon D Manning
Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, USA
Clin Infect Dis 39:380-8. 2004..Large prospective studies are needed to better understand colonization site-specific factors for GBS and to clarify potential transmission modes... - Features of invasive staphylococcal disease in neonatesC Mary Healy
Department of Pediatrics, Section of Infectious Diseases, Baylor College of Medicine, One Baylor Plaza, Rm 302A, Houston, TX 77030, USA
Pediatrics 114:953-61. 2004..We aimed to describe the contemporary incidence, clinical features, and outcome of infants with ISD in a neonatal intensive care unit... - Emergence of new strains of methicillin-resistant Staphylococcus aureus in a neonatal intensive care unitC Mary Healy
Section of Infectious Diseases, Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA
Clin Infect Dis 39:1460-6. 2004..We determined if MRSA strains causing bacteremia in infants treated from birth in a neonatal intensive care unit (NICU) demonstrated the genetic traits of community-associated MRSA... - Antibodies to type III group B streptococcal polysaccharide in breast milkMorven S Edwards
Department of Pediatrics, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA
Pediatr Infect Dis J 23:961-3. 2004.... - Group B streptococcal colonization and serotype-specific immunity in healthy elderly personsMorven S Edwards
Section of Infectious Diseases, Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA
Clin Infect Dis 40:352-7. 2005..Rates of colonization and prevalence of antibodies against capsular polysaccharides (CPS) that might confer protection against invasive GBS disease in such persons are not defined... - Pertussis serostatus among neonates born to Hispanic womenC Mary Healy
Department of Pediatrics, Section of Infectious Diseases, Baylor College of Medicine, Houston, Texas 77030, USA
Clin Infect Dis 42:1439-42. 2006..63 EU/mL; P < or =.001). A lack of maternal immunity is one explanation for pertussis susceptibility in very young Hispanic infants... - DNA macrorestriction analysis of nontypeable group B streptococcal isolates: clonal evolution of nontypeable and type V isolatesNicole R Amundson
Department of Laboratory Medicine and Pathology, University of Minnesota Medical School, 420 Delaware St. SE, Minneapolis, MN 55455, USA
J Clin Microbiol 43:572-6. 2005..PFGE is a valuable approach for comparison of GBS isolate relatedness and for monitoring of NT and typeable GBS isolates for potential clonal divergence... - Fluconazole prophylaxis in extremely low birth weight neonates reduces invasive candidiasis mortality rates without emergence of fluconazole-resistant Candida speciesC Mary Healy
Department of Pediatrics, Section of Infectious Diseases, Baylor College of Medicine, One Baylor Plaza, Room 302A, MS BCM 320, Houston, TX 77030, USA
Pediatrics 121:703-10. 2008..We evaluated the impact of fluconazole prophylaxis for extremely low birth weight infants on invasive candidiasis incidence, invasive candidiasis-related mortality rates, and fluconazole susceptibility of Candida isolates... - Alpha C protein-specific immunity in humans with group B streptococcal colonization and invasive diseasePia S Pannaraj
Section of Infectious Diseases, Department of Pediatrics, Baylor College of Medicine and Texas Children s Hospital, Houston, TX 77030, USA
Vaccine 26:502-8. 2008..In vitro killing of alpha C-expressing GBS correlated with total alpha C-specific antibody concentration. Invasive disease but not colonization elicits alpha C-specific IgM and IgG in adults... - Group B Streptococcus bacteremia elicits beta C protein-specific IgMand IgG in humansPia S Pannaraj
Section of Infectious Diseases, Department of Pediatrics, Baylor College of Medicine and Texas Children s Hospital, Houston, TX 77030, USA
J Infect Dis 195:353-6. 2007..Serum from 3 women with beta C GBS bacteremia had significantly higher levels of IgM (6.0) and IgG (52.9) (P=.01 and 0.01, respectively). Invasive disease but not colonization elicits beta C-specific IgM and IgG... - Impact of fluconazole prophylaxis on incidence and outcome of invasive candidiasis in a neonatal intensive care unitC Mary Healy
Department of Pediatrics, Baylor College of Medicine and The Woman s Hospital of Texas, Houston, Texas 77030, USA
J Pediatr 147:166-71. 2005.... - Maternal immunizationC Mary Healy
Department of Pediatrics, Section of Infectious Diseases, Baylor College of Medicine, Houston, TX, USA
Pediatr Infect Dis J 26:945-8. 2007 - Prevalence of pertussis antibodies in maternal delivery, cord, and infant serumC Mary Healy
Section of Infectious Diseases, Department of Pediatrics, Baylor College of Medicine, Houston, Texas, USA
J Infect Dis 190:335-40. 2004..Passively acquired maternal antibodies protect infants from many pathogens. With increasing reports of infant pertussis, we evaluated pertussis antibodies in maternal-infant paired sera from 1999-2000... - Group B Streptococcus colonization in male and nonpregnant female university students: a cross-sectional prevalence studySandra J Bliss
Department of Internal Medicine and Pediatrics, University of Michigan Medical School, Ann Arbor, MI, USA
Clin Infect Dis 34:184-90. 2002..However, larger studies are needed to verify these findings... - Induction of cross-reactive antibodies by immunization of healthy adults with types Ia and Ib group B streptococcal polysaccharide-tetanus toxoid conjugate vaccinesAnne Karin Brigtsen
Channing Laboratory, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA
J Infect Dis 185:1277-84. 2002..These results indicate that GBS Ia and Ib PSs should be included in a multivalent conjugate vaccine to prevent GBS disease... - Type III group B streptococcal polysaccharide induces antibodies that cross-react with Streptococcus pneumoniae type 14Hilde Kari Guttormsen
Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
Infect Immun 70:1724-38. 2002..When present, these vaccine-induced cross-reacting antibodies conferred in vitro antibody-mediated opsonophagocytosis and killing of both GBS III and Pn14, two pathogens that cause invasive disease in young infants... - Correlates of antibiotic-resistant group B streptococcus isolated from pregnant womenShannon D Manning
Department of Epidemiology and Center for Molecular and Clinical Epidemiology of Infectious Diseases, University of Michigan School of Public Health, Ann Arbor, Michigan 48109-0276, USA
Obstet Gynecol 101:74-9. 2003..A better understanding of factors associated with antibiotic resistance is needed to minimize group B streptococcus disease risks and to maximize effective chemoprophylaxis... - Use of type V group B streptococcal conjugate vaccine in adults 65-85 years oldDebra L Palazzi
Section of Infectious Diseases, Department of Pediatrics, Baylor College of Medicine, Houston, Texas 77030, USA
J Infect Dis 190:558-64. 2004..These results suggest the potential for prevention of invasive type V GBS infections in healthy elderly adults through immunization... - Quantitative determination of immunoglobulin G specific for group B streptococcal beta C protein in human maternal serumCatherine S Lachenauer
Channing Laboratory and Division of Infectious Diseases, Children s Hospital, Harvard Medical School, Boston, MA 02115, USA
J Infect Dis 185:368-74. 2002..This difference was not explained by a major difference in epitope specificity... - New recommendations for prevention of early-onset group B streptococcal disease in newbornsWilliam P Kanto
Department of Pediatrics, Medical College of Georgia, Atlanta, GA, USA
Pediatr Rev 24:219-21. 2003 - Healthy elderly people lack neutrophil-mediated functional activity to type V group B StreptococcusRene A Amaya
Departments of Pediatrics and Molecular Virology and Microbiology, Section of Infectious Disease, Baylor College of Medicine, Houston, Texas 77030, USA
J Am Geriatr Soc 52:46-50. 2004..Further studies should determine whether a type V GBS vaccine induces functionally active antibodies in older people... - Group B streptococcal infections in elderly adultsMorven S Edwards
Section of Infectious Disease, Department of Pediatrics, Baylor College of Medicine, Houston, Texas 77030, USA
Clin Infect Dis 41:839-47. 2005..The safety and immunogenicity of GBS serotype V-tetanus toxoid conjugate vaccine in healthy elderly persons suggest the potential for vaccination as an approach to prevention of invasive GBS infections in elderly persons... - Comparison of DNA dot blot hybridization and lancefield capillary precipitin methods for group B streptococcal capsular typingStephanie M Borchardt
Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan 48109, USA
J Clin Microbiol 42:146-50. 2004..The overall agreement between the methods was 95% (256 of 270 isolates typeable by both methods). We conclude that the DBCT method is a specific and useful alternative to the commonly used LS method... - Multilocus sequence typing of serotype III group B streptococcus and correlation with pathogenic potentialH Dele Davies
Department of Microbiology, and Child Health Research Unit, Alberta Children s Hospital, University of Calgary, Canada
J Infect Dis 189:1097-102. 2004..89 microg/mL and 0.39 microg/mL, respectively) for ST-19 and ST-17 (P=.86). The close association of genomic strain 2603V/R (serotype V) with ST-19 suggests that the phenomenon of capsule switching may have occurred... - Improved methods for typing nontypeable isolates of group B streptococciJeffrey A Benson
Department of Laboratory Medicine, University of Minnesota Medical School, Minneapolis 55455, USA
Int J Med Microbiol 292:37-42. 2002..8%) had DNA profiles that resembled those of specific types of GBS. These approaches will be useful for classification of NT isolates in continued epidemiological surveillance associated with GBS vaccine trials... - Another success for hepatitis A vaccineCarol J Baker
N Engl J Med 357:1757-9. 2007 - Prevention of influenza: recommendations for influenza immunization of children, 2007-2008Joseph A Bocchini
Pediatrics 121:e1016-31. 2008..However, oseltamivir and zanamivir can be prescribed for treatment or chemoprophylaxis, because influenza A and B strains remain susceptible... - Growth, survival and viral load in symptomatic childhood human immunodeficiency virus infectionCaroline J Chantry
Department of Pediatrics, University of California Davis Medical Center, Sacramento 95817, USA
Pediatr Infect Dis J 22:1033-9. 2003..The relationships among weight and height growth, viral load and survival in HIV-infected children remain unclear... - Prospects for prevention of childhood infections by maternal immunizationC Mary Healy
Section of Infectious Diseases, Department of Pediatrics, Baylor College of Medicine, Houston, Texas 77030, USA
Curr Opin Infect Dis 19:271-6. 2006..To review the literature on using maternal immunization as a strategy to prevent infections in young infants aged below 6 months.. - Determinants of co-colonization with group B streptococcus among heterosexual college couplesShannon D Manning
Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI, USA
Epidemiology 13:533-9. 2002..Future studies should evaluate the role of the pharynx and examine the effects of both bacterial characteristics and host response on transmission... - Advances in antifungal therapyPia S Pannaraj
National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
Pediatr Infect Dis J 24:921-2. 2005 - The future of meningococcal vaccinesC Mary Healy
Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA
Pediatr Infect Dis J 24:175-6. 2005 - Mutations linked to drug resistance, human immunodeficiency virus type 1 biologic phenotype and their association with disease progression in children receiving nucleoside reverse transcriptase inhibitorsJanet A Englund
University of Chicago, Pritzker School of Medicine, Chicago, IL, USA
Pediatr Infect Dis J 23:15-22. 2004.... - Population pharmacokinetics and pharmacodynamics of zidovudine in HIV-infected infants and childrenEdmund V Capparelli
University of California, San Diego, School of Medicine, La Jolla, California, USA
J Clin Pharmacol 43:133-40. 2003..It was concluded that ZDV oral clearance is reduced in infants compared to older children. This lower clearance leads to higher ZDV exposure in infants and contributes to increased hematologic toxicity...