W Wang

Summary

Affiliation: Bayer HealthCare
Country: USA

Publications

  1. ncbi request reprint Dual effects of Tween 80 on protein stability
    Wei Wang
    Pfizer Inc, Global Biologics, 700 Chesterfield Parkway West, Chesterfield, MO 63017, USA
    Int J Pharm 347:31-8. 2008
  2. ncbi request reprint Coagulation factor VIII: structure and stability
    Wei Wang
    Analytics and Formulation, Biotechnology Division, Bayer HealthCare, 800 Dwight Way, Berkeley, CA 94701, USA
    Int J Pharm 259:1-15. 2003
  3. ncbi request reprint Peroxide formation in polysorbate 80 and protein stability
    Emily Ha
    Analytics and Formulation Department, Process Sciences, Bayer Biotechnology, 800 Dwight Way, Berkeley, California 94701, USA
    J Pharm Sci 91:2252-64. 2002
  4. ncbi request reprint Correlation of rFVIII inactivation with aggregation in solution
    Wei Wang
    Analytics and Formulation, Process Sciences, Biotechnology, Bayer Corp, 800 Dwight Way, Berkeley, California 94701, USA
    Pharm Res 20:693-700. 2003
  5. ncbi request reprint Antibody structure, instability, and formulation
    Wei Wang
    Pfizer, Inc, Global Biologics, 700 Chesterfield Parkway West, Chesterfield, Missouri 63017, USA
    J Pharm Sci 96:1-26. 2007
  6. ncbi request reprint Lyophilization and development of solid protein pharmaceuticals
    W Wang
    Biotechnology, Bayer Corporation, 800 Dwight Way, Berkeley, CA 94701, USA
    Int J Pharm 203:1-60. 2000
  7. ncbi request reprint A novel method for removing residual acetone from gelatin microspheres
    Wei Wang
    Biotechnology, Bayer Corporation, Berkeley, CA 94701, USA
    Pharm Dev Technol 7:169-80. 2002
  8. ncbi request reprint Oxidation of protein by vaporized sanitizing agents
    Wei Wang
    Analytics and Formulation, Biotechnology Division, Bayer HealthCare, Berkeley, CA 94701, USA
    PDA J Pharm Sci Technol 58:121-9. 2004
  9. ncbi request reprint Instability, stabilization, and formulation of liquid protein pharmaceuticals
    W Wang
    Biotechnology, Bayer Corporation, 800 Dwight Way, Berkeley, CA 94701, USA
    Int J Pharm 185:129-88. 1999
  10. ncbi request reprint Stabilization of a polypeptide in non-aqueous solvents
    Wei Wang
    Bayer HealthCare, 800 Dwight Way, Berkeley, CA 94701, United States
    Int J Pharm 351:1-7. 2008

Collaborators

Detail Information

Publications64

  1. ncbi request reprint Dual effects of Tween 80 on protein stability
    Wei Wang
    Pfizer Inc, Global Biologics, 700 Chesterfield Parkway West, Chesterfield, MO 63017, USA
    Int J Pharm 347:31-8. 2008
    ..Addition of 0.1% Tween 80 not only increased the rate of oxidation in general but also altered the temperature-dependency of IL-2 mutein oxidation...
  2. ncbi request reprint Coagulation factor VIII: structure and stability
    Wei Wang
    Analytics and Formulation, Biotechnology Division, Bayer HealthCare, 800 Dwight Way, Berkeley, CA 94701, USA
    Int J Pharm 259:1-15. 2003
    ....
  3. ncbi request reprint Peroxide formation in polysorbate 80 and protein stability
    Emily Ha
    Analytics and Formulation Department, Process Sciences, Bayer Biotechnology, 800 Dwight Way, Berkeley, California 94701, USA
    J Pharm Sci 91:2252-64. 2002
    ....
  4. ncbi request reprint Correlation of rFVIII inactivation with aggregation in solution
    Wei Wang
    Analytics and Formulation, Process Sciences, Biotechnology, Bayer Corp, 800 Dwight Way, Berkeley, California 94701, USA
    Pharm Res 20:693-700. 2003
    ..This study was designed to investigate the stability of recombinant FVIII (rFVIII) in solution at different pHs and to probe the cause(s) of rFVIII inactivation under accelerated storage conditions...
  5. ncbi request reprint Antibody structure, instability, and formulation
    Wei Wang
    Pfizer, Inc, Global Biologics, 700 Chesterfield Parkway West, Chesterfield, Missouri 63017, USA
    J Pharm Sci 96:1-26. 2007
    ..Various aspects of formulation development have been examined to identify the critical attributes for the stabilization of antibodies...
  6. ncbi request reprint Lyophilization and development of solid protein pharmaceuticals
    W Wang
    Biotechnology, Bayer Corporation, 800 Dwight Way, Berkeley, CA 94701, USA
    Int J Pharm 203:1-60. 2000
    ....
  7. ncbi request reprint A novel method for removing residual acetone from gelatin microspheres
    Wei Wang
    Biotechnology, Bayer Corporation, Berkeley, CA 94701, USA
    Pharm Dev Technol 7:169-80. 2002
    ..To develop a method for removing residual acetone from gelatin microspheres...
  8. ncbi request reprint Oxidation of protein by vaporized sanitizing agents
    Wei Wang
    Analytics and Formulation, Biotechnology Division, Bayer HealthCare, Berkeley, CA 94701, USA
    PDA J Pharm Sci Technol 58:121-9. 2004
    ..These results strongly suggest that the sanitization process needs to be properly controlled and closely monitored during manufacturing of drug products that are sensitive to oxidation...
  9. ncbi request reprint Instability, stabilization, and formulation of liquid protein pharmaceuticals
    W Wang
    Biotechnology, Bayer Corporation, 800 Dwight Way, Berkeley, CA 94701, USA
    Int J Pharm 185:129-88. 1999
    ....
  10. ncbi request reprint Stabilization of a polypeptide in non-aqueous solvents
    Wei Wang
    Bayer HealthCare, 800 Dwight Way, Berkeley, CA 94701, United States
    Int J Pharm 351:1-7. 2008
    ..The stabilization approaches are applicable only in a non-aqueous environment for this peptide, and possibly for other peptides with similar reactive moieties...
  11. ncbi request reprint pH dependent effect of glycosylation on protein stability
    Wei Wang
    Pfizer Inc, Global Biologics, 700 Chesterfield Parkway West, Chesterfield, MO 63017, USA
    Eur J Pharm Sci 33:120-7. 2008
    ..0 and both forms are most stable at pH 5.5 in terms of thermal stability, precipitation rate and total degradation rate. This study clearly demonstrates that the effect of glycosylation on the stability of a protein is pH-dependent...
  12. ncbi request reprint [Peptide mapping analysis of recombinant human interleukin-11 with HPLC-ESI-Q-TOF/MS spectrometry]
    Ying Yang
    National Institute for the Control of Pharmaceutical and Biological Products, Beijing 100050, China
    Yao Xue Xue Bao 41:756-60. 2006
    ..To analyze the peptide mapping of recombinant human interleukin-11 (rhIL-11) by HPLC-ESI-Q-TOF/MS spectrometry...
  13. ncbi request reprint Evaluation of the in vitro and in vivo genotoxicity of magnolia bark extract
    Ning Li
    Department of Toxicological Safety Assessment, National Institute for Nutrition and Food Safety, Chinese Center for Disease Control and Prevention, Beijing, China
    Regul Toxicol Pharmacol 49:154-9. 2007
    ..The results of these studies demonstrate that MBE is not genotoxic under the conditions of the in vitro bacterial reverse mutation assay and the in vivo micronucleus test, and support the safety of MBE for dietary consumption...
  14. ncbi request reprint Role of glycosylation in corin zymogen activation
    Xudong Liao
    Department of Molecular Cardiology, Cleveland Clinic, Cleveland, Ohio 44195, USA
    J Biol Chem 282:27728-35. 2007
    ..Mutations altering the two N-glycosylation sites in the protease domain of rat corin prevented its activation in HEK 293 and HL-1 cells. Our results indicate that N-linked oligosaccharides play an important role in corin activation...
  15. ncbi request reprint Grouping of amino acids and recognition of protein structurally conserved regions by reduced alphabets of amino acids
    Jing Li
    National Laboratory of Solid State Microstructure and Department of Physics, Nanjing University, Nanjing, 210093, China
    Sci China C Life Sci 50:392-402. 2007
    ..The results indicate that the accuracy or efficiency of sequence alignment can be improved with the optimal reduced alphabet with N around 9...
  16. ncbi request reprint In vivo culture of encapsulated endostatin-secreting Chinese hamster ovary cells for systemic tumor inhibition
    Ying Zhang
    Laboratory of Biomedical Material Engineering, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, People s Republic of China
    Hum Gene Ther 18:474-81. 2007
    ..4% and enhanced the survival of treated mice to 80% by 27 days posttreatment. Continuous systemic release of endostatin from microcapsules offers an effective therapeutic strategy to eradicate solid tumors...
  17. ncbi request reprint [VNTR polymorphism of C6orf37 in Chinese population]
    Jing Cui
    Department of Pathology, College of Medicine, Zhejiang University, Hangzhou 310031, China
    Zhejiang Da Xue Xue Bao Yi Xue Ban 35:354-9. 2006
    ..To identify a novel VNTR in C6orf37 and to detect the C6orf37 VNTR polymorphism distribution in Chinese population...
  18. ncbi request reprint Self-assembly of nano-hydroxyapatite on multi-walled carbon nanotubes
    Susan Liao
    Nanoscience and Nanotechnology Initiative, Division of Bioengineering, Faculty of Engineering, National University of Singapore, Singapore 117576, Singapore
    Acta Biomater 3:669-75. 2007
    ..Spindle-shaped units that are detached from the MWCNT template are able to maintain the ordered parallel structure of the nHA polycrystal fibril. We have thus created a self-assembled hydroxyapatite on MWCNTs...
  19. ncbi request reprint Scanning tunneling microscopy study of DNA-chromophore motif on solid surfaces
    Wenli Deng
    College of Materials Science and Engineering, South China University of Technology, Guangzhou 510640, China
    J Phys Chem B 111:6544-8. 2007
    ....
  20. ncbi request reprint Optimization of microencapsulated recombinant CHO cell growth, endostatin production, and stability of microcapsule in vivo
    Ying Zhang
    Laboratory of Biomedical Material Engineering, Dalian Institute of Chemical Physics, Chinese, Academy of Sciences, Dalian 116023, People s Republic of China
    J Biomed Mater Res B Appl Biomater 84:79-88. 2008
    ..The optimized microencapsulation conditions for in vivo implantation are liquid core and 240 microm in diameter. This study provides useful information for antiangiogenic gene therapy to tumors using microencapsulated recombinant cells...
  21. ncbi request reprint Combinatorial protein design strategies using computational methods
    Hidetoshi Kono
    Computational Biology Group, Neutron Science Research Center, Quantum Beam Science Directorate, Japan Atomic Energy Agency, Kyoto, Japan
    Methods Mol Biol 352:3-22. 2007
    ..Such methods may be used to guide the construction of both individual sequences and combinatorial libraries of proteins...
  22. ncbi request reprint The selective retention of lutein, meso-zeaxanthin and zeaxanthin in the retina of chicks fed a xanthophyll-free diet
    YingMing Wang
    Division of Endocrinology, Diabetes and Clinical Nutrition, Department of Medicine, L465, Oregon Health and Science University, Portland, OR 972391, USA
    Exp Eye Res 84:591-8. 2007
    ..It is clear that these xanthophylls may have an essential role in the cone-rich retina of the chick as evidenced by their selective retention...
  23. ncbi request reprint Characterization of active phenolic components in the ethanolic extract of Ananas comosus L. leaves using high-performance liquid chromatography with diode array detection and tandem mass spectrometry
    Chao Ma
    Laboratory of Pharmaceutical Sciences, Department of Biological Sciences and Biotechnology, Tsinghua University, Beijing 100084, China
    J Chromatogr A 1165:39-44. 2007
    ..Meanwhile, a new HPLC-DAD-MS method was established for the identification and characterization of phenylpropane diglycerides in natural plants...
  24. ncbi request reprint Acute electrical stimulation of nucleus ambiguus enhances immune function in rats
    Ying Wu Mei
    College of Animal Science and Veterinary Medicine, Jilin University, Changchun, China
    Can J Neurol Sci 35:441-7. 2008
    ....
  25. doi request reprint Redox modulation of long-term potentiation in the hippocampus via regulation of the glycogen synthase kinase-3beta pathway
    Fei Cai
    Department of Pharmacology, Tongji Medical College, Wuhan, Hubei 430030, China
    Free Radic Biol Med 45:964-70. 2008
    ..These findings will benefit the understanding of the redox contribution to the mechanisms underlying synaptic plasticity and AD pathogenesis...
  26. doi request reprint All-atom replica exchange molecular simulation of protein BBL
    Jian Zhang
    Department of Physics, National Laboratory of Solid State Microstructure, Institute of Biophysics, Nanjing University, Nanjing, China
    Proteins 72:1038-47. 2008
    ..Compared with the experimental data (Sadqi et al., Nature 2006; 442:317), our results indicate that the Naf-BBL (pH5.3) may have an even lower barrier height and cooperativity...
  27. doi request reprint Discovery of azetidinone acids as conformationally-constrained dual PPARalpha/gamma agonists
    Wei Wang
    Metabolic Diseases Chemistry, Bristol Myers Squibb Research and Development, Princeton, NJ 08543 5400, USA
    Bioorg Med Chem Lett 18:1939-44. 2008
    ..Synthesis, in vitro and in vivo activities of compounds in this series are described. A high-yielding method for N-arylation of azetidinone esters is also described...
  28. doi request reprint Influence of pH on the aggregation morphology of a novel surfactant with single hydrocarbon chain and multi-amine headgroups
    Wei Wang
    Beijing National Laboratory for Molecular Sciences, Key Laboratory of Colloid and Interface Science, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100080, People s Republic of China
    J Phys Chem B 112:1409-13. 2008
    ....
  29. doi request reprint Identifying folding nucleus based on residue contact networks of proteins
    Jie Li
    National Laboratory of Solid State Microstructure, Department of Physics, Nanjing University, Nanjing 210093, China
    Proteins 71:1899-907. 2008
    ..Our study shows that the FNRs can be identified solely from the native structures of proteins based on the analysis of residue contact network without any knowledge of the transition state ensemble...
  30. doi request reprint Crystal structure of long-chain alkane monooxygenase (LadA) in complex with coenzyme FMN: unveiling the long-chain alkane hydroxylase
    Liu Li
    Tsinghua Nankai IBP Joint Research Group for Structural Biology, Tsinghua University, Beijing 100084, China
    J Mol Biol 376:453-65. 2008
    ..The LadA structure opens a rational perspective to explore and alter the substrate binding site of LadA, with potential biotechnological applications in areas such as petroleum exploration and treatment of environmental oil pollution...
  31. ncbi request reprint HMGA1a protein unfolds or refolds synthetic DNA-chromophore hybrid polymers: a chaperone-like behavior
    Wei Wan
    Department of Chemistry, Washington State University, Pullman, WA 99164, USA
    Chembiochem 9:304-11. 2008
    ..The unfolding mechanisms and the binding stoichiometry of protein-hybrid polymers depended on the sequence of the synthetic polymers...
  32. pmc On the detection of functionally coherent groups of protein domains with an extension to protein annotation
    William A McLaughlin
    Department of Chemistry and Biochemistry, Center for Theoretical Biological Physics, University of California, San Diego, 9500 Gilman Drive La Jolla, CA 92093 0359, USA
    BMC Bioinformatics 8:390. 2007
    ..Further effort is needed to identify groups of domains that span across two or more proteins and are linked by a cooperative function. Such functional domain combinations can be useful for protein annotation...
  33. ncbi request reprint Effects of solution conditions, processing parameters, and container materials on aggregation of a monoclonal antibody during freeze-thawing
    Lisa A Kueltzo
    Center for Pharmaceutical Biotechnology, Department of Pharmaceutical Sciences, University of Colorado Health Sciences Center, 4200 East 9th Avenue, Denver, Colorado 80262, USA
    J Pharm Sci 97:1801-12. 2008
    ..Samples stressed in plastic or glass containers contained low amounts of aggregate. Storage in Teflon or commercial freezing containers, however, led to significantly higher levels of aggregate formation...
  34. ncbi request reprint Triptolide alters mitochondrial functions
    Ying Su
    Department of Radiation Oncology, University of Rochester Medical Center, Rochester, NY 14642, USA
    Adv Exp Med Biol 599:139-46. 2007
    ..It is likely that by impairment of mitochondrial function, TPL exerts its inhibitory effect on growth of tumor and progression of inflammatory disease...
  35. ncbi request reprint Proliferation, viability, and metabolism of human tumor and normal cells cultured in microcapsule
    Xulang Zhang
    Laboratory of Biomedical Material Engineering, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, 457 Zhongshan Road, Dalian 116023, China
    Appl Biochem Biotechnol 134:61-76. 2006
    ..In addition, it lays a solid foundation for the use of microencapsulation in cell culture in vitro and cell implantation in vivo...
  36. ncbi request reprint Conditional gene modification in mouse liver using hydrodynamic delivery of plasmid DNA encoding Cre recombinase
    Huan Zhang Zhu
    State Key Laboratory of Genetic Engineering, Institute of Genetics, School of Life Sciences, Fudan University, Shanghai 200433, China
    FEBS Lett 580:4346-52. 2006
    ..Thus, hydrodynamic gene delivery of the Cre recombinase provides a valuable approach for Cre-loxP-mediated conditional gene modification in the liver of mice...
  37. ncbi request reprint Adsorption mechanism at the molecular level between polymers and uremic octapeptide by the 2D 1H NMR Technique
    Guohua Li
    The Key Laboratory of Functional Polymer Materials, Ministry of Education, Institute of Polymer Chemistry, Nankai University, Tianjin 300071, People s Republic of China
    Biomacromolecules 7:1811-8. 2006
    ....
  38. ncbi request reprint [Human peripheral blood CD4+ T-lymphocytes reconstituting severe combined immunodeficient mouse-human cell immune system and its immunological function]
    Qiu Hua Zeng
    Department of Radiology, Third Xiangya Hospital, Central South University, Chaengsha 410013, China
    Zhong Nan Da Xue Xue Bao Yi Xue Ban 29:513-6. 2004
    ....
  39. ncbi request reprint Development of an in vitro multicellular tumor spheroid model using microencapsulation and its application in anticancer drug screening and testing
    Xulang Zhang
    Laboratory of Biomedical Material Engineering, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, 457 Zhongshan Road, Dalian 116023, China
    Biotechnol Prog 21:1289-96. 2005
    ..It demonstrated that the MMTS has the potential to be a rapid and valid in vitro model to screen chemotherapeutic drugs with a feature to mimic in vivo three-dimensional (3-D) cell growth pattern...
  40. ncbi request reprint Separation and determination of flavonoids in Agrimonia pilosa Ledeb. by capillary electrophoresis with electrochemical detection
    Xueqin Xu
    Department of Chemistry, Fuzhou University, Fuzhou, Fujian, 350002, China
    J Sep Sci 28:647-52. 2005
    ..02 to 0.05 microg/mL for all compounds. This method was successfully used to determine the above five flavonoids in Agrimonia pilosa Ledeb. with relatively simple extraction procedures, and the assay results were satisfactory...
  41. ncbi request reprint Development and evaluation of an enzyme-linked immunosorbent assay for detection of antibodies against the spike protein of SARS-coronavirus
    Jincun Zhao
    Department of Immunology, Peking University Health Science Center, 38 Xueyuan Road, Beijing 100083, PR China
    J Clin Virol 33:12-8. 2005
    ..Amino acid residues 450-650 of the spike (S) glycoprotein of SARS-CoV (S450-650) contains dominant epitopes for anti-viral antibodies (Abs) in patient sera...
  42. ncbi request reprint High performance liquid chromatographic-mass spectrometric determination of ginsenoside Rg3 and its metabolites in rat plasma using solid-phase extraction for pharmacokinetic studies
    Hai tang Xie
    Key Laboratory of Drug Metabolism and Pharmacokinetics, 24 Tong Jia Xiang Street, Mail Box 210, China Pharmaceutical University, Nanjing 210009, Jiangsu Province, China
    J Chromatogr B Analyt Technol Biomed Life Sci 818:167-73. 2005
    ..1, 0.02 and 0.08 ng in each 10 microl injection onto the HPLC column) for Rg3, Rh2 and ppd, respectively. The method has been demonstrated to be highly sensitive and accurate for the determination of Rg3 and its metabolites in rat plasma...
  43. ncbi request reprint Protein aggregation and its inhibition in biopharmaceutics
    Wei Wang
    Biotechnology Division, Bayer HealthCare, 800 Dwight Way, Berkeley, CA 94701, USA
    Int J Pharm 289:1-30. 2005
    ....
  44. ncbi request reprint [Determination of entrapment efficiency of breviscapine nanoliposomes]
    Fei Xiong
    Institute of Pharmaceutics, China Pharmaceutical University, Nanjing 210009, China
    Yao Xue Xue Bao 39:755-7. 2004
    ..To determine the entrapment efficiency of breviscapine nanoliposomes...
  45. ncbi request reprint Molecular and biochemical characterization of the Skp2-Cks1 binding interface
    Wei Wang
    Department of Chemistry and Biochemistry, University of Colorado Boulder, Boulder, Colorado 80309, USA
    J Biol Chem 279:51362-9. 2004
    ..These results uncovered the specificity of the Skp2-Cks1 interaction and reveal a critical function for the structurally flexible carboxyl-terminal tail region of Skp2 in Cks1 recognition and substrate ubiquitination...
  46. ncbi request reprint Thermodynamic stability and kinetic foldability of a lattice protein model
    Jie Li
    National Lab of Solid State Microstructure and Physics Department, Nanjing University, Nanjing 210093, China
    J Chem Phys 120:6274-87. 2004
    ..The folding of model proteins with the MMJ potentials is fast. However, the relationship between the foldability and the thermodynamic stability of the mutated sequences is complex...
  47. ncbi request reprint The number of protein folds and their distribution over families in nature
    Xinsheng Liu
    National Lab of Solid State Microstructure, Department of Physics and Institute of Biophysics, Nanjing University, Nanjing, China
    Proteins 54:491-9. 2004
    ..In addition, the method of directly "enlarging" the sample to the population may be useful in inferring distributions of species in different fields...
  48. ncbi request reprint Computational design and characterization of a monomeric helical dinuclear metalloprotein
    Jennifer R Calhoun
    Department of Biochemistry and Molecular Biophysics, Johnson Foundation, School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
    J Mol Biol 334:1101-15. 2003
    ..DFsc is then a realization of complete de novo design, where backbone structure, activity, and sequence are specified in the design process...
  49. pmc Autophosphorylation of the catalytic subunit of the DNA-dependent protein kinase is required for efficient end processing during DNA double-strand break repair
    Qi Ding
    College of Veterinary Medicine and Department of Pathobiology and Diagnostic Investigation, Michigan State University, East Lansing, Michigan 48824, USA
    Mol Cell Biol 23:5836-48. 2003
    ..However, autophosphorylation at these sites may not be sufficient for kinase disassembly...
  50. ncbi request reprint Folding behavior of chaperonin-mediated substrate protein
    Wei Xin Xu
    National Laboratory of Solid State Microstructure, Department of Physics, Nanjing University, Nanjing, China
    Proteins 61:777-94. 2005
    ....
  51. ncbi request reprint Determination of schizandrin in rat plasma by high-performance liquid chromatography-mass spectrometry and its application in rat pharmacokinetic studies
    Meijuan Xu
    Key Lab of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing 210009, China
    J Chromatogr B Analyt Technol Biomed Life Sci 828:55-61. 2005
    ..005, 0.100 and 1.000 microg/mL. Intra- and inter-day relative standard deviations were 5.95-12.93% and 3.87-14.53%, respectively. This method was successfully applied for the pharmacokinetic studies in rats...
  52. pmc Structure-based function inference using protein family-specific fingerprints
    Deepak Bandyopadhyay
    Department of Computer Science, University of North Carolina at Chapel Hill, North Carolina 27599, USA
    Protein Sci 15:1537-43. 2006
    ..Some predictions have been corroborated by other computational methods and some validated by subsequent functional characterization...
  53. ncbi request reprint Preparation of spherical iron nanoclusters in ethanol-water solution for nitrate removal
    Wei Wang
    College of Environment Science and Engineering, Nankai University, Nankai District, Tianjin, PR China
    Chemosphere 65:1396-404. 2006
    ..Finally, kinetic analysis revealed that chemical reduction of nitrate by HNZVI could not be described by the first- or pseudo-first-order kinetic model...
  54. ncbi request reprint Reversal of the malignant phenotype of cervical cancer CaSki cells through adeno-associated virus-mediated delivery of HPV16 E7 antisense RNA
    Sufang Wu
    Cancer Biology Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, Republic of China
    Clin Cancer Res 12:2032-7. 2006
    ....
  55. ncbi request reprint Carbon nanotubes for immunomagnetic separation of Escherichia coli O157: H7
    Yi Lin
    Department of Chemistry, Laboratory for Emerging Materials and Technology, Clemson University, Clemson, SC 29634 097, USA
    J Nanosci Nanotechnol 6:868-71. 2006
    ....
  56. ncbi request reprint Identification of a novel VNTR polymorphism in C6orf37 and its association with colorectal cancer risk in Chinese population
    Jing Cui
    Department of Pathology, School of Medicine, Zhejiang University, Yan An Road 353, Hangzhou, 310031, China
    Clin Chim Acta 368:155-9. 2006
    ..C6orf37 was a gene up-regulated in colorectal adenoma in our previous study. A variable region of C6orf37 sequence was found when we blasted its full sequence with NCBI nucleotide database...
  57. ncbi request reprint Freeze-drying of liposomes using tertiary butyl alcohol/water cosolvent systems
    JingXia Cui
    School of Pharmacy, Hebei Medical University, No 361, Zhongshan East Road, Shijiazhuang City, Hebei Province 050017, PR China
    Int J Pharm 312:131-6. 2006
    ..In addition, in conjunction with a modified injection method, this FD technology might be used to produce dehydrated HSPC liposomes on a large scale...
  58. ncbi request reprint Folding with downhill behavior and low cooperativity of proteins
    Guanghong Zuo
    Department of Physics, Nanjing University, China
    Proteins 63:165-73. 2006
    ..These could enable us to identify the downhill folding or the cooperative two-state folding behavior solely from the native structures of proteins...
  59. ncbi request reprint New surface-enhanced Raman spectroscopy substrates via self-assembly of silver nanoparticles for perchlorate detection in water
    Wei Wang
    Environmental Sciences Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee 37831, USA
    Appl Spectrosc 59:1509-15. 2005
    ..These capillary flow cells could be readily configured to allow for in situ, nondestructive detection of ClO4- via fiber optics...
  60. ncbi request reprint Exploiting sequence and structure homologs to identify protein-protein binding sites
    Jo Lan Chung
    Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla 92093 0537, USA
    Proteins 62:630-40. 2006
    ..The results support the hypothesis that in many cases protein interfaces require some residues to provide rigidity to minimize the entropic cost upon complex formation...
  61. ncbi request reprint Identification and determination of major flavonoids in rat urine by HPLC-UV and HPLC-MS methods following oral administration of Dalbergia odorifera extract
    Rongxia Liu
    School of Pharmaceutical Sciences, Peking University, Beijing 100083, People s Republic of China
    Biomed Chromatogr 20:101-8. 2006
    ..odorifera extract...
  62. ncbi request reprint The use of LC/MS, GC/MS, and LC/NMR hyphenated techniques to identify a drug degradation product in pharmaceutical development
    Changkang Pan
    Pharmaceutical and Analytical Development, Novartis Pharmaceuticals Corporation, One Health Plaza, East Hanover, NJ 07936, USA
    J Pharm Biomed Anal 40:581-90. 2006
    ..The combination approach is critical for unambiguous impurity structure elucidation in drug degradation studies of pharmaceutical drug products...
  63. ncbi request reprint Folding behaviors of lattice model proteins with three kinds of contact potentials
    Meng Qin
    National Laboratory of Solid State Microstructure and Department of Physics, Nanjing University, China
    Phys Rev E Stat Nonlin Soft Matter Phys 67:061905. 2003
    ..The formations of various contacts are also analyzed, which provide us with some microscopic information on the model systems and interaction potentials...
  64. ncbi request reprint Identification and characterization of AGTRAP, a human homolog of murine Angiotensin II Receptor-Associated Protein (Agtrap)
    Wei Wang
    State Key Laboratory of Genetic Engineering, Institute of Genetics, School of Life Sciences, Fudan University, Shanghai 200433, People s Republic of China
    Int J Biochem Cell Biol 34:93-102. 2002
    ..We suggest that the AGTRAP-RACK1 interaction may help to recruit signaling complex to the AT(1) receptor to affect AT(1) receptor signaling...