Lars Kuepfer

Summary

Affiliation: Bayer HealthCare
Country: USA

Publications

  1. pmc Integrating cellular metabolism into a multiscale whole-body model
    Markus Krauss
    Bayer Technology Services GmbH, Computational Systems Biology, Leverkusen, Germany
    PLoS Comput Biol 8:e1002750. 2012
  2. doi request reprint Multiscale mechanistic modeling in pharmaceutical research and development
    Lars Kuepfer
    Systems Biology and Computational Solutions, Bayer Technology Services GmbH, Building 9115, 51368 Leverkusen, Germany
    Adv Exp Med Biol 736:543-61. 2012
  3. doi request reprint Using expression data for quantification of active processes in physiologically based pharmacokinetic modeling
    Michaela Meyer
    Systems Biology and Computational Solutions, Bayer Technology Services GmbH, Building 9115, 51368 Leverkusen, Germany
    Drug Metab Dispos 40:892-901. 2012
  4. pmc Development of a physiologically based computational kidney model to describe the renal excretion of hydrophilic agents in rats
    Christoph Niederalt
    Computational Systems Biology, Bayer Technology Services GmbH Leverkusen, Germany
    Front Physiol 3:494. 2012

Collaborators

  • Stefan Willmann
  • Markus Krauss
  • Christoph Niederalt
  • Joerg Lippert
  • Michaela Meyer
  • Julia Winkler
  • Thomas Wendl
  • Rolf Findeisen
  • Philipp Lengsfeld
  • Karina Claassen
  • Roland Loosen
  • Steffen Borchers
  • Marcus Schultze-Mosgau
  • Stephan Schaller
  • Hubertus Pietsch
  • Jörg Lippert
  • Matthias Brautigam
  • Bernd Ludewig
  • Rolf Burghaus
  • Sebastian Schneckener

Detail Information

Publications5

  1. pmc Integrating cellular metabolism into a multiscale whole-body model
    Markus Krauss
    Bayer Technology Services GmbH, Computational Systems Biology, Leverkusen, Germany
    PLoS Comput Biol 8:e1002750. 2012
    ..The approach presented may in future support a mechanistic understanding in diagnostics and drug development...
  2. doi request reprint Multiscale mechanistic modeling in pharmaceutical research and development
    Lars Kuepfer
    Systems Biology and Computational Solutions, Bayer Technology Services GmbH, Building 9115, 51368 Leverkusen, Germany
    Adv Exp Med Biol 736:543-61. 2012
    ....
  3. doi request reprint Using expression data for quantification of active processes in physiologically based pharmacokinetic modeling
    Michaela Meyer
    Systems Biology and Computational Solutions, Bayer Technology Services GmbH, Building 9115, 51368 Leverkusen, Germany
    Drug Metab Dispos 40:892-901. 2012
    ....
  4. pmc Development of a physiologically based computational kidney model to describe the renal excretion of hydrophilic agents in rats
    Christoph Niederalt
    Computational Systems Biology, Bayer Technology Services GmbH Leverkusen, Germany
    Front Physiol 3:494. 2012
    ....