Uday R Khire

Summary

Affiliation: Bayer HealthCare
Country: USA

Publications

  1. ncbi request reprint Omega-carboxypyridyl substituted ureas as Raf kinase inhibitors: SAR of the amide substituent
    Uday R Khire
    Department of Chemistry Research, Bayer Research Center, 400Morgan Lane, West Haven, CT 06516, USA
    Bioorg Med Chem Lett 14:783-6. 2004
  2. ncbi request reprint Quinazolinone derivatives as orally available ghrelin receptor antagonists for the treatment of diabetes and obesity
    Joachim Rudolph
    Department of Chemistry Research, Bayer Pharmaceuticals Corporation, 400 Morgan Lane, West Haven, Connecticut 06516, USA
    J Med Chem 50:5202-16. 2007

Detail Information

Publications2

  1. ncbi request reprint Omega-carboxypyridyl substituted ureas as Raf kinase inhibitors: SAR of the amide substituent
    Uday R Khire
    Department of Chemistry Research, Bayer Research Center, 400Morgan Lane, West Haven, CT 06516, USA
    Bioorg Med Chem Lett 14:783-6. 2004
    ..Based on this finding, we hypothesize that this portion of the molecule is directed towards the solvent in Raf-1...
  2. ncbi request reprint Quinazolinone derivatives as orally available ghrelin receptor antagonists for the treatment of diabetes and obesity
    Joachim Rudolph
    Department of Chemistry Research, Bayer Pharmaceuticals Corporation, 400 Morgan Lane, West Haven, Connecticut 06516, USA
    J Med Chem 50:5202-16. 2007
    ..In vivo efficacy evaluation of selected compounds revealed suppression of food intake and body weight reduction as well as glucose-lowering effects mediated by glucose-dependent insulin secretion...