Mark S Bauer

..In a multiregion effectiveness trial in veterans with bipolar disorder, the authors assessed the effects of a collaborative care model for this disorder on guideline concordance in care over a 3-year period...

..Recent data indicate high prevalence of both anxiety and substance comorbidity in bipolar disorder. However, few studies have utilized public sector samples, and only one has attempted to separate contributions of each type of comorbidity...

..The study addressed whether a collaborative model for chronic care, described in part I (this issue), improves outcome for bipolar disorder...

..Understanding barriers for treated populations is particularly important in optimizing care for high vulnerability populations, such as those with mental illness and the elderly...

..Part II (see companion article, this issue) reports clinical, functional, and overall cost outcomes of the trial...

..Little is known about medical comorbidity or health-related quality of life (HRQOL) in bipolar disorder across the adult age span, especially in public sector patients...

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..It is unclear which aspect of medical comorbidity is responsible: simple disease count, risk for future morbidity, or current physical burden...

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..The association between early childhood abuse and the course of illness, including psychiatric comorbidities, in adults with bipolar disorder has not been examined in a predominantly male or veteran population...

..Depressive and manic symptoms were positively, not inversely, correlated, and their co-occurrence was associated with worse quality of life. Implications for the DSM and ICD nosological systems are discussed...

..Our study therefore examines monitoring and prevalence of metabolic syndrome in patients with SMI, including those not using SGAs...

..However, few data are available to inform the suicidality risk assessment of antidepressant use specifically in bipolar disorder...

..However, the public health challenge is to design and implement interventions that are sustainable in general clinical practice...

..They review the literature on the efficacy of agents in any of these four roles to determine which if any agents meet this definition of mood stabilizer...

..Despite the availability of efficacious treatments, the long-term course of bipolar disorder is often unfavorable...

..However, the pattern of specific deficits has not been well studied, and the role of potential confounders has received no attention...

..In fact, the younger group showed a trend for decreased suicidality (P = .13). Thus, increased suicidality risk with paroxetine exposure does not extend to this other high-risk mood disordered population, even among younger individuals...

..We compared perceived access to and satisfaction with health care between patients diagnosed with serious mental illness (SMI: schizophrenia or bipolar disorder) and among those with no SMI diagnosis...

..Maintaining a beneficial therapeutic alliance with providers is one important strategy for improving adherence. We examine the association between adherence and therapeutic environment perceptions among veterans with bipolar disorder...

..The aim of this secondary analysis from a larger study was to identify the association between baseline variables and average treatment adherence over a subsequent three-year period...

..This pilot study examined a bipolar disorder medical care model (BCM) and determined whether, compared with usual care, individuals randomly assigned to receive BCM care had improved medical and psychiatric outcomes...

..Bipolar patients with suicidal ideation may benefit from different treatment strategies depending on their prior attempt status...

..This column describes how the partnership formed, key elements of its success, and challenges and opportunities to inform future research partnerships...

..This report describes the design and implementation of a randomized trial evaluating a systematic program to improve quality and continuity of care for bipolar disorder...

..The current report provides a context for interpreting studies resulting from STEP-BD by summarizing the baseline demographic and diagnostic characteristics of the first 1000 enrolled...

..Our findings highlight the need for greater clinical guidance and treatment options for patients with bipolar disorder and comorbidity...

..This trial evaluated the effectiveness of a multi-component care management program in a population-based sample of people with bipolar disorder...

..It is important that clinicians and care providers gather information related to patients' perceptions of the patient-provider relationship when designing or evaluating services aimed at enhancing treatment adherence...

..CONCLUSIONS: Although a majority of patients received guideline-concordant care for bipolar disorder, potential gaps in continuity of outpatient care may exist for African-American patients...

..Treatment nonadherence has been identified as an understudied, yet frequent, cause of relapse among patients with bipolar disorder. This study evaluated factors related to treatment adherence...

..This report describes the development and evaluation of a brief measure for assessing patient perception of providers' support for self-management of bipolar disorder...

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..This format will be particularly useful for studies that require processing of large numbers of ISSs, such as those that collect frequent ratings over long periods of time and/or those that utilize large samples...

..The ISS may be more sensitive to mood symptoms with prednisone than clinician-rated scales...

..CONCLUSIONS: Rapid-cycling BD is associated with a latent hypofunction of the HPT system. This dysfunction becomes manifest with short-term lithium challenge...

..More research is needed to develop programs to improve outcomes for children with depression and adults with bipolar disorders...

..We review the literature, identify key gaps, and recommend new research to guide national efforts to reduce the burden of affective disorders...

..We investigated whether different forms of psychotherapy consisted of overlapping versus modality-specific ingredients...

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..To examine the relationship between changes in mood symptoms and changes in functioning or disability in people treated for bipolar disorder...

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..We assessed whether patients with bipolar disorder received serum drug level and toxicity monitoring for mood stabilizers and assessment of cardiovascular disease (CVD)-related risk factors attributed to atypical antipsychotic medications...

..Given limited health care resources, assessment of the value for the cost of second-generation antipsychotics relative to first-generation antipsychotics is critical for resource-allocation decisions...

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..In this article, we review the evidence for, and implications of, a high rate of comorbid posttraumatic stress disorder (PTSD) in individuals with bipolar disorder...

..Finally, he identifies the shortcomings and sources of potential bias in our evidence base, which is critical for an accurate reading of the literature now and in the future...

..This study represents the first randomized trial of competing options for treatment-resistant bipolar depression and assesses the effectiveness and safety of antidepressant augmentation with lamotrigine, inositol, and risperidone...