Nicholas J Heyer

Summary

Affiliation: Battelle Memorial Institute
Country: USA

Publications

  1. ncbi request reprint Effectiveness of practices to reduce blood sample hemolysis in EDs: a laboratory medicine best practices systematic review and meta-analysis
    Nicholas J Heyer
    Battelle Centers for Public Health Research and Evaluation, USA
    Clin Biochem 45:1012-32. 2012
  2. doi request reprint Use of historical data and a novel metric in the evaluation of the effectiveness of hearing conservation program components
    Nicholas Heyer
    Battelle CPHRE, 1100 Dexter Ave N, Suite 400, Seattle, WA 98109 3598, USA
    Occup Environ Med 68:510-7. 2011
  3. pmc The association between serotonin transporter gene promoter polymorphism (5-HTTLPR), self-reported symptoms, and dental mercury exposure
    Nicholas J Heyer
    Battelle Centers for Public Health Research and Evaluation, Seattle, Washington 98109 3598, USA
    J Toxicol Environ Health A 71:1318-26. 2008
  4. pmc The association between serotonin transporter gene promotor polymorphism (5-HTTLPR) and elemental mercury exposure on mood and behavior in humans
    Diana Echeverria
    Battelle Centers for Public Health Research and Evaluation, 1100 Dexter Ave N, Suite 400, Seattle, WA 98109 3598, USA
    J Toxicol Environ Health A 73:1003-20. 2010
  5. pmc Catechol O-methyltransferase (COMT) VAL158MET functional polymorphism, dental mercury exposure, and self-reported symptoms and mood
    Nicholas J Heyer
    Battelle Centers for Public Health Research and Evaluation, Seattle, WA, USA
    J Toxicol Environ Health A 72:599-609. 2009
  6. ncbi request reprint Chronic low-level mercury exposure, BDNF polymorphism, and associations with cognitive and motor function
    Diana Echeverria
    Battelle Centers for Public Health Research and Evaluation, Seattle, WA 98109, USA
    Neurotoxicol Teratol 27:781-96. 2005
  7. ncbi request reprint The association between a genetic polymorphism of coproporphyrinogen oxidase, dental mercury exposure and neurobehavioral response in humans
    Diana Echeverria
    Battelle Centers for Public Health Research and Evaluation, 1100 Dexter Avenue North, Suite 400, Seattle, WA 98109, United States
    Neurotoxicol Teratol 28:39-48. 2006
  8. ncbi request reprint Chronic low-level mercury exposure, BDNF polymorphism, and associations with self-reported symptoms and mood
    Nicholas J Heyer
    Battelle Centers for Public Health Research and Evaluation, Seattle, Washington, USA
    Toxicol Sci 81:354-63. 2004
  9. pmc Modification of neurobehavioral effects of mercury by a genetic polymorphism of coproporphyrinogen oxidase in children
    James S Woods
    Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, WA 98105, USA
    Neurotoxicol Teratol 34:513-21. 2012
  10. ncbi request reprint A cascade analysis of the interaction of mercury and coproporphyrinogen oxidase (CPOX) polymorphism on the heme biosynthetic pathway and porphyrin production
    Nicholas J Heyer
    Battelle Centers for Public Health Research and Evaluation, 1100 Dexter Avenue N, Suite 400, Seattle, WA 98109, USA
    Toxicol Lett 161:159-66. 2006

Detail Information

Publications14

  1. ncbi request reprint Effectiveness of practices to reduce blood sample hemolysis in EDs: a laboratory medicine best practices systematic review and meta-analysis
    Nicholas J Heyer
    Battelle Centers for Public Health Research and Evaluation, USA
    Clin Biochem 45:1012-32. 2012
    ..To complete a systematic review of emergency department (ED) practices for reducing hemolysis in blood samples sent to the clinical laboratory for testing...
  2. doi request reprint Use of historical data and a novel metric in the evaluation of the effectiveness of hearing conservation program components
    Nicholas Heyer
    Battelle CPHRE, 1100 Dexter Ave N, Suite 400, Seattle, WA 98109 3598, USA
    Occup Environ Med 68:510-7. 2011
    ..To evaluate the effectiveness of hearing conservation programs (HCP) and their specific components in reducing noise-induced hearing loss (NIHL)...
  3. pmc The association between serotonin transporter gene promoter polymorphism (5-HTTLPR), self-reported symptoms, and dental mercury exposure
    Nicholas J Heyer
    Battelle Centers for Public Health Research and Evaluation, Seattle, Washington 98109 3598, USA
    J Toxicol Environ Health A 71:1318-26. 2008
    ..These findings suggest that within this restricted population increased symptoms of depression, anxiety, and memory are associated with the 5-HTTLPR polymorphism among both males and females...
  4. pmc The association between serotonin transporter gene promotor polymorphism (5-HTTLPR) and elemental mercury exposure on mood and behavior in humans
    Diana Echeverria
    Battelle Centers for Public Health Research and Evaluation, 1100 Dexter Ave N, Suite 400, Seattle, WA 98109 3598, USA
    J Toxicol Environ Health A 73:1003-20. 2010
    ..These results add to the growing evidence of genetic determinants of mood and behavior that potentially increase susceptibility to Hg toxicity in humans...
  5. pmc Catechol O-methyltransferase (COMT) VAL158MET functional polymorphism, dental mercury exposure, and self-reported symptoms and mood
    Nicholas J Heyer
    Battelle Centers for Public Health Research and Evaluation, Seattle, WA, USA
    J Toxicol Environ Health A 72:599-609. 2009
    ..These findings extend evidence of genetic factors potentially affecting human susceptibility to the toxic effects of mercury and other environmental chemicals...
  6. ncbi request reprint Chronic low-level mercury exposure, BDNF polymorphism, and associations with cognitive and motor function
    Diana Echeverria
    Battelle Centers for Public Health Research and Evaluation, Seattle, WA 98109, USA
    Neurotoxicol Teratol 27:781-96. 2005
    ..No associations were observed with estimates of chronic mercury exposure. Our findings are applicable to exposure levels of the general population and identify a potentially vulnerable group with a BDNF polymorphism...
  7. ncbi request reprint The association between a genetic polymorphism of coproporphyrinogen oxidase, dental mercury exposure and neurobehavioral response in humans
    Diana Echeverria
    Battelle Centers for Public Health Research and Evaluation, 1100 Dexter Avenue North, Suite 400, Seattle, WA 98109, United States
    Neurotoxicol Teratol 28:39-48. 2006
    ..These exploratory findings suggest that the CPOX4 polymorphism may affect susceptibility for specific neurobehavioral functions associated with mercury exposure in human subjects...
  8. ncbi request reprint Chronic low-level mercury exposure, BDNF polymorphism, and associations with self-reported symptoms and mood
    Nicholas J Heyer
    Battelle Centers for Public Health Research and Evaluation, Seattle, Washington, USA
    Toxicol Sci 81:354-63. 2004
    ..The BDNF polymorphism is also associated with increased symptom and mood scores. Notably, Hg degrees and BDNF polymorphism were additive with respect to their associations with the same symptom group...
  9. pmc Modification of neurobehavioral effects of mercury by a genetic polymorphism of coproporphyrinogen oxidase in children
    James S Woods
    Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, WA 98105, USA
    Neurotoxicol Teratol 34:513-21. 2012
    ..The paucity of responses among same-age girls with comparable Hg exposure provides evidence of sexual dimorphism in genetic susceptibility to the adverse neurobehavioral effects of Hg in children and adolescents...
  10. ncbi request reprint A cascade analysis of the interaction of mercury and coproporphyrinogen oxidase (CPOX) polymorphism on the heme biosynthetic pathway and porphyrin production
    Nicholas J Heyer
    Battelle Centers for Public Health Research and Evaluation, 1100 Dexter Avenue N, Suite 400, Seattle, WA 98109, USA
    Toxicol Lett 161:159-66. 2006
    ..Additionally, these findings demonstrate the successful application of a computational model for characterizing complex metabolic responses and interactions associated with both toxicant exposure and genetic variation in human subjects...
  11. ncbi request reprint The association between genetic polymorphisms of coproporphyrinogen oxidase and an atypical porphyrinogenic response to mercury exposure in humans
    James S Woods
    Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, WA 98101, USA Battelle Centers for Public Health Research and Evaluation, Seattle, WA 98105, USA
    Toxicol Appl Pharmacol 206:113-20. 2005
    ..This finding represents the first report of a polymorphism in a human gene that modifies the effect of Hg on a biological process. The APR might serve as a biomarker of both Hg exposure and susceptibility to Hg toxicity...
  12. pmc Disordered porphyrin metabolism: a potential biological marker for autism risk assessment
    Nicholas J Heyer
    Battelle Centers for Public Health Research and Evaluation, Seattle, Washington, USA
    Autism Res 5:84-92. 2012
    ....
  13. pmc Urinary porphyrin excretion in neurotypical and autistic children
    James S Woods
    Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, Washington 98105, USA
    Environ Health Perspect 118:1450-7. 2010
    ....
  14. ncbi request reprint Test-retest reliability and factor stability of the behavioral evaluation for epidemiology studies test battery
    Diana Echeverria
    Battelle Center for Public Health Research and Evaluation, Seattle, WA 98105, USA
    Percept Mot Skills 95:845-67. 2002
    ..These results strongly support recommendation of the new test battery for use in repeated-measures epidemiologic studies where first trial stability is desired...