Donald J Messner

Summary

Affiliation: Bastyr University
Country: USA

Publications

  1. pmc Iron overload causes oxidative stress and impaired insulin signaling in AML-12 hepatocytes
    Donald J Messner
    Bastyr University, 14500 Juanita Drive NE, Kenmore, WA 98028 4966, USA
    Dig Dis Sci 58:1899-908. 2013
  2. pmc Neoplastic transformation of rat liver epithelial cells is enhanced by non-transferrin-bound iron
    Donald J Messner
    Bastyr University, 14500 Juanita Drive, Kenmore, WA 98028, USA
    BMC Gastroenterol 8:2. 2008
  3. pmc Curcumin reduces the toxic effects of iron loading in rat liver epithelial cells
    Donald J Messner
    Bastyr University Research Center, Bastyr University, Kenmore, WA 98028, USA
    Liver Int 29:63-72. 2009
  4. ncbi request reprint Inhibition of PP2A, but not PP5, mediates p53 activation by low levels of okadaic acid in rat liver epithelial cells
    Donald J Messner
    Department of Biochemistry, Purdue University, West Lafayette, Indiana 47907, USA
    J Cell Biochem 99:241-55. 2006

Collaborators

Detail Information

Publications4

  1. pmc Iron overload causes oxidative stress and impaired insulin signaling in AML-12 hepatocytes
    Donald J Messner
    Bastyr University, 14500 Juanita Drive NE, Kenmore, WA 98028 4966, USA
    Dig Dis Sci 58:1899-908. 2013
    ..Iron overload is associated with increased severity of nonalcoholic fatty liver disease (NAFLD) including progression to nonalcoholic steatohepatitis and hepatocellular carcinoma...
  2. pmc Neoplastic transformation of rat liver epithelial cells is enhanced by non-transferrin-bound iron
    Donald J Messner
    Bastyr University, 14500 Juanita Drive, Kenmore, WA 98028, USA
    BMC Gastroenterol 8:2. 2008
    ..The primary aim of this study was to investigate NTBI-related hepatic carcinogenesis using T51B rat liver epithelial cells, a non-neoplastic cell line previously developed for carcinogenicity and tumor promotion studies...
  3. pmc Curcumin reduces the toxic effects of iron loading in rat liver epithelial cells
    Donald J Messner
    Bastyr University Research Center, Bastyr University, Kenmore, WA 98028, USA
    Liver Int 29:63-72. 2009
    ..The aim of this study was to quantify its effects on iron overload and the resulting downstream toxic effects in cultured T51B rat liver epithelial cells...
  4. ncbi request reprint Inhibition of PP2A, but not PP5, mediates p53 activation by low levels of okadaic acid in rat liver epithelial cells
    Donald J Messner
    Department of Biochemistry, Purdue University, West Lafayette, Indiana 47907, USA
    J Cell Biochem 99:241-55. 2006
    ..In contrast, specific blockade of PP2A mimics p53-related responses to OA in T51B cells, suggesting that PP2A is the target for this response to OA...