A Baskys

Summary

Country: USA

Publications

  1. ncbi Changes in hippocampal gene expression after neuroprotective activation of group I metabotropic glutamate receptors
    Morten Blaabjerg
    Anatomy and Neurobiology, University of Southern Denmark, Odense, Denmark
    Brain Res Mol Brain Res 117:196-205. 2003
  2. ncbi Neuroprotective effects of extracellular glutamate are absent in hippocampal organotypic cultures treated with the amyloid peptide Abeta(25-35)
    A Baskys
    Department of Physiology, University of Toronto, Toronto, Ontario, M5T 2S8, Canada
    Brain Res 907:188-94. 2001
  3. ncbi Group I metabotropic glutamate receptors reduce excitotoxic injury and may facilitate neurogenesis
    Andrius Baskys
    Department of Mental Health, VA Health Care System, Mental Illness Research and Education Clinical Center, Long Beach, University of California at Irvine, 06 116A, 5901 East Seventh Street Long Beach, CA, 90822 Irvine, CA, USA
    Neuropharmacology 49:146-56. 2005
  4. ncbi Lewy body dementia: the litmus test for neuroleptic sensitivity and extrapyramidal symptoms
    Andrius Baskys
    Department of Psychiatry and Human Behavior, University of California at Irvine, USA
    J Clin Psychiatry 65:16-22. 2004
  5. ncbi Understanding regulation of nerve cell death by mGluRs as a method for development of successful neuroprotective strategies
    Andrius Baskys
    06 116 VA Health Care System MIRECC, 5901 E 7th Street, Long Beach, CA 90822, USA
    J Neurol Sci 229:201-9. 2005
  6. ncbi Activation of neuroprotective pathways by metabotropic group I glutamate receptors: a potential target for drug discovery?
    Andrius Baskys
    Southern California Institute for Research and Education, Long Beach, California 90822, USA
    Ann N Y Acad Sci 1053:55-73. 2005
  7. ncbi Haloperidol and loxapine but not clozapine increase synaptic responses in the hippocampus
    A Baskys
    Department of Physiology, University of Toronto, Ont, Canada
    Eur J Pharmacol 235:305-7. 1993
  8. ncbi Vascular dementia: pharmacological treatment approaches and perspectives
    Andrius Baskys
    Department of Psychiatry and Human Behavior, University of California at Irvine, Irvine, California, USA
    Clin Interv Aging 2:327-35. 2007
  9. ncbi Rab-mediated endocytosis: linking neurodegeneration, neuroprotection, and synaptic plasticity?
    Andrius Baskys
    Memory Disorders Program, VA HCS Long Beach, 5901 E 7th St 06 116 A, Long Beach, CA 90822, USA
    Ann N Y Acad Sci 1122:313-29. 2007
  10. ncbi Recognizing and responding to atypical antipsychotic side effects
    Jeanne M Jackson-Siegal
    J Am Med Dir Assoc 5:H7-10. 2004

Collaborators

Detail Information

Publications12

  1. ncbi Changes in hippocampal gene expression after neuroprotective activation of group I metabotropic glutamate receptors
    Morten Blaabjerg
    Anatomy and Neurobiology, University of Southern Denmark, Odense, Denmark
    Brain Res Mol Brain Res 117:196-205. 2003
    ..By providing insight into genes involved in neuroprotection these data may help to identify novel therapeutic targets...
  2. ncbi Neuroprotective effects of extracellular glutamate are absent in hippocampal organotypic cultures treated with the amyloid peptide Abeta(25-35)
    A Baskys
    Department of Physiology, University of Toronto, Toronto, Ontario, M5T 2S8, Canada
    Brain Res 907:188-94. 2001
    ..These data suggest that one of the mechanisms responsible for amyloid toxicity may be inhibition of the survival promoting effects of extracellular glutamate...
  3. ncbi Group I metabotropic glutamate receptors reduce excitotoxic injury and may facilitate neurogenesis
    Andrius Baskys
    Department of Mental Health, VA Health Care System, Mental Illness Research and Education Clinical Center, Long Beach, University of California at Irvine, 06 116A, 5901 East Seventh Street Long Beach, CA, 90822 Irvine, CA, USA
    Neuropharmacology 49:146-56. 2005
    ....
  4. ncbi Lewy body dementia: the litmus test for neuroleptic sensitivity and extrapyramidal symptoms
    Andrius Baskys
    Department of Psychiatry and Human Behavior, University of California at Irvine, USA
    J Clin Psychiatry 65:16-22. 2004
    ..Quetiapine has been shown to reduce psychiatric manifestations of DLB without causing neuroleptic sensitivity or increasing EPS. Hence, quetiapine is an attractive candidate for the treatment of psychoses in DLB and other dementias...
  5. ncbi Understanding regulation of nerve cell death by mGluRs as a method for development of successful neuroprotective strategies
    Andrius Baskys
    06 116 VA Health Care System MIRECC, 5901 E 7th Street, Long Beach, CA 90822, USA
    J Neurol Sci 229:201-9. 2005
    ..Combined pharmacological targeting of these processes may provide basis for clinical trials of effective neuroprotective compounds...
  6. ncbi Activation of neuroprotective pathways by metabotropic group I glutamate receptors: a potential target for drug discovery?
    Andrius Baskys
    Southern California Institute for Research and Education, Long Beach, California 90822, USA
    Ann N Y Acad Sci 1053:55-73. 2005
    ..These findings expand our understanding of the role that mGluRs play in regulation of nerve cell susceptibility to injury and should facilitate the design of novel therapeutic strategies for stroke and other neurodegenerative diseases...
  7. ncbi Haloperidol and loxapine but not clozapine increase synaptic responses in the hippocampus
    A Baskys
    Department of Physiology, University of Toronto, Ont, Canada
    Eur J Pharmacol 235:305-7. 1993
    ..These data suggest that haloperidol and loxapine may act by enhancing excitatory synaptic transmission in some areas of the brain, and that novel antipsychotic clozapine differs in its mechanism of action...
  8. ncbi Vascular dementia: pharmacological treatment approaches and perspectives
    Andrius Baskys
    Department of Psychiatry and Human Behavior, University of California at Irvine, Irvine, California, USA
    Clin Interv Aging 2:327-35. 2007
    ....
  9. ncbi Rab-mediated endocytosis: linking neurodegeneration, neuroprotection, and synaptic plasticity?
    Andrius Baskys
    Memory Disorders Program, VA HCS Long Beach, 5901 E 7th St 06 116 A, Long Beach, CA 90822, USA
    Ann N Y Acad Sci 1122:313-29. 2007
    ....
  10. ncbi Recognizing and responding to atypical antipsychotic side effects
    Jeanne M Jackson-Siegal
    J Am Med Dir Assoc 5:H7-10. 2004
  11. ncbi Neuroprotection against NMDA excitotoxicity by group I metabotropic glutamate receptors is associated with reduction of NMDA stimulated currents
    Morten Blaabjerg
    Anatomy and Neurobiology, University of Southern Denmark-Odense, Denmark
    Exp Neurol 183:573-80. 2003
    ..We conclude that neuroprotection induced by activation of group-I-mGluRs involve mGluR1 and is associated with decreased NMDA-stimulated currents...
  12. ncbi Antisense oligonucleotide against GTPase Rab5b inhibits metabotropic agonist DHPG-induced neuroprotection
    Andrea L H Arnett
    Southern California Institute for Research and Education (SCIRE, USA
    Brain Res 1028:59-65. 2004
    ..These data suggest that neuroprotection by DHPG against NMDA-mediated injury may involve facilitation of NMDA receptor endocytosis likely stimulated by DHPG-induced increase in Rab5b synthesis...