Affiliation: Barrow Neurological Institute
Wu J, Takeo T, Suga S, Kanno T, Osanai T, Mikoshiba K, et al
. 2-aminoethoxydiphenyl borate inhibits agonist-induced Ca2+ signals by blocking inositol trisphosphate formation in acutely dissociated mouse pancreatic acinar cells. Pflugers Arch. 2004;448:592-5 pubmed
Wu J, Javedan S, Ellsworth K, Smith K, Fisher R. Gamma oscillation underlies hyperthermia-induced epileptiform-like spikes in immature rat hippocampal slices. BMC Neurosci. 2001;2:18 pubmed
..These results suggest that the GABA(A) receptor-governed gamma oscillations underlie the hyperthermic population spike activity in immature hippocampal slices. ..
Wu J, Xu L, Kim D, Rho J, St John P, Lue L, et al
. Electrophysiological properties of human hypothalamic hamartomas. Ann Neurol. 2005;58:371-82 pubmed
..These findings suggest that human HH tissues, associated with gelastic seizures, contained predominantly small GABAergic inhibitory neurons that exhibited intrinsic "pacemaker-like" behavior. ..
Hu J, Lindenberger K, Hu G, Wang H, Lukas R, Wu J. Iptakalim as a human nicotinic acetylcholine receptor antagonist. J Pharmacol Exp Ther. 2006;316:914-25 pubmed
..Thus, alpha4beta2-nAChRs are among the molecular targets of Ipt, which has utility as a tool in functional characterization and pharmacological profiling of nAChRs. ..
Wu J, Ellsworth K, Ellsworth M, Schroeder K, Smith K, Fisher R. Abnormal benzodiazepine and zinc modulation of GABAA receptors in an acquired absence epilepsy model. Brain Res. 2004;1013:230-40 pubmed
..The present results are also consistent with recent findings that mutation of the gamma2 subunit of the GABAA receptor changes benzodiazepine modulation in families with generalized epilepsy syndromes. ..