Jasmohan S Bajaj

Summary

Country: USA

Publications

  1. ncbi Clostridium difficile is associated with poor outcomes in patients with cirrhosis: A national and tertiary center perspective
    Jasmohan S Bajaj
    Department of Medicine, Virginia Commonwealth University and McGuire VA Medical Center, Richmond, 23249, USA
    Am J Gastroenterol 105:106-13. 2010
  2. ncbi Inhibitory control test for the diagnosis of minimal hepatic encephalopathy
    Jasmohan S Bajaj
    Division of Gastroenterology, Hepatology, and Nutrition, Virginia Commonwealth University and McGuire VA Medical Center, Richmond, Virginia, USA
    Gastroenterology 135:1591-1600.e1. 2008
  3. ncbi Patients with minimal hepatic encephalopathy have poor insight into their driving skills
    Jasmohan S Bajaj
    Division of Gastroenterology, Hepatology and Nutrition, Virginia Commonwealth University, Richmond, Virginia, USA
    Clin Gastroenterol Hepatol 6:1135-9; quiz 1065. 2008
  4. ncbi Management options for minimal hepatic encephalopathy
    Jasmohan S Bajaj
    Division of Gastroenterology, Hepatology and Nutrition, Virginia Commonwealth University and McGuire VA Medical Center, 1201 Broad Rock Boulevard, Richmond, VA 23221, USA
    Expert Rev Gastroenterol Hepatol 2:785-90. 2008
  5. ncbi The effect of fatigue on driving skills in patients with hepatic encephalopathy
    Jasmohan S Bajaj
    Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, Virginia Commonwealth University and McGuire VA Medical Center, Richmond, Virginia 23249, USA
    Am J Gastroenterol 104:898-905. 2009
  6. ncbi Association of proton pump inhibitor therapy with spontaneous bacterial peritonitis in cirrhotic patients with ascites
    Jasmohan S Bajaj
    Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, McGuire VA Medical Center, Virginia Commonwealth University, Richmond, Virginia 23221, USA
    Am J Gastroenterol 104:1130-4. 2009
  7. ncbi Minimal hepatic encephalopathy is associated with motor vehicle crashes: the reality beyond the driving test
    Jasmohan S Bajaj
    Division of Gastroenterology, Hepatology and Nutrition, Virginia Commonwealth University and McGuire VA Medical Center, Richmond, VA 23221, USA
    Hepatology 50:1175-83. 2009
  8. ncbi A longitudinal systems biology analysis of lactulose withdrawal in hepatic encephalopathy
    Jasmohan S Bajaj
    Division of Gastroenterology, Hepatology and Nutrition, Virginia Commonwealth University and McGuire VA Medical Center, Richmond, 23249, USA
    Metab Brain Dis 27:205-15. 2012
  9. ncbi Driving simulation can improve insight into impaired driving skills in cirrhosis
    Jasmohan S Bajaj
    Division of Gastroenterology, Hepatology and Nutrition, Virginia Commonwealth University and McGuire VA Medical Center, 1201 Broad Rock Boulevard, Richmond, VA 23249, USA
    Dig Dis Sci 57:554-60. 2012
  10. ncbi Rifaximin improves driving simulator performance in a randomized trial of patients with minimal hepatic encephalopathy
    Jasmohan S Bajaj
    Division of Gastroenterology, Hepatology and Nutrition, Virginia Commonwealth University and McGuire VA Medical Center, Richmond, Virginia 23249, USA
    Gastroenterology 140:478-487.e1. 2011

Collaborators

Detail Information

Publications27

  1. ncbi Clostridium difficile is associated with poor outcomes in patients with cirrhosis: A national and tertiary center perspective
    Jasmohan S Bajaj
    Department of Medicine, Virginia Commonwealth University and McGuire VA Medical Center, Richmond, 23249, USA
    Am J Gastroenterol 105:106-13. 2010
    ..The aim was to define the effect of CDAD on outcomes and identify risk factors for its development in cirrhosis...
  2. ncbi Inhibitory control test for the diagnosis of minimal hepatic encephalopathy
    Jasmohan S Bajaj
    Division of Gastroenterology, Hepatology, and Nutrition, Virginia Commonwealth University and McGuire VA Medical Center, Richmond, Virginia, USA
    Gastroenterology 135:1591-1600.e1. 2008
    ..We studied the reliability and validity of ICT for MHE diagnosis...
  3. ncbi Patients with minimal hepatic encephalopathy have poor insight into their driving skills
    Jasmohan S Bajaj
    Division of Gastroenterology, Hepatology and Nutrition, Virginia Commonwealth University, Richmond, Virginia, USA
    Clin Gastroenterol Hepatol 6:1135-9; quiz 1065. 2008
    ..DBS consists of a total score (maximum, 104) and an attention-related driving skills section (maximum, 40). DBS was used to compare self-assessment with observer-assessment of driving skills in cirrhotic patients tested for MHE...
  4. ncbi Management options for minimal hepatic encephalopathy
    Jasmohan S Bajaj
    Division of Gastroenterology, Hepatology and Nutrition, Virginia Commonwealth University and McGuire VA Medical Center, 1201 Broad Rock Boulevard, Richmond, VA 23221, USA
    Expert Rev Gastroenterol Hepatol 2:785-90. 2008
    ..Therapy can improve the quality of life in MHE patients but the natural history, specific diagnostic strategies and treatment options are still being investigated...
  5. ncbi The effect of fatigue on driving skills in patients with hepatic encephalopathy
    Jasmohan S Bajaj
    Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, Virginia Commonwealth University and McGuire VA Medical Center, Richmond, Virginia 23249, USA
    Am J Gastroenterol 104:898-905. 2009
    ..Hepatic encephalopathy, both overt (OHE) and minimal (MHE), is associated with poor quality of life and fatigue. The aim of this study was to define the effect of fatigue on driving skills in MHE and OHE patients...
  6. ncbi Association of proton pump inhibitor therapy with spontaneous bacterial peritonitis in cirrhotic patients with ascites
    Jasmohan S Bajaj
    Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, McGuire VA Medical Center, Virginia Commonwealth University, Richmond, Virginia 23221, USA
    Am J Gastroenterol 104:1130-4. 2009
    ..The aim of this study was to determine whether PPI use in cirrhotics with ascites is associated with SBP...
  7. ncbi Minimal hepatic encephalopathy is associated with motor vehicle crashes: the reality beyond the driving test
    Jasmohan S Bajaj
    Division of Gastroenterology, Hepatology and Nutrition, Virginia Commonwealth University and McGuire VA Medical Center, Richmond, VA 23221, USA
    Hepatology 50:1175-83. 2009
    ..ICT, but not SPT performance is significantly associated with prior and future crashes and violations. There was an excellent agreement between self- and DOT-reports...
  8. ncbi A longitudinal systems biology analysis of lactulose withdrawal in hepatic encephalopathy
    Jasmohan S Bajaj
    Division of Gastroenterology, Hepatology and Nutrition, Virginia Commonwealth University and McGuire VA Medical Center, Richmond, 23249, USA
    Metab Brain Dis 27:205-15. 2012
    ..HE recurrence post-lactulose withdrawal can be predicted by baseline cognitive performance and is accompanied by disrupted choline metabolism...
  9. ncbi Driving simulation can improve insight into impaired driving skills in cirrhosis
    Jasmohan S Bajaj
    Division of Gastroenterology, Hepatology and Nutrition, Virginia Commonwealth University and McGuire VA Medical Center, 1201 Broad Rock Boulevard, Richmond, VA 23249, USA
    Dig Dis Sci 57:554-60. 2012
    ..Minimal hepatic encephalopathy (MHE) is associated with poor driving skills and insight. Increasing insight may improve receptiveness for therapy or driving restrictions...
  10. ncbi Rifaximin improves driving simulator performance in a randomized trial of patients with minimal hepatic encephalopathy
    Jasmohan S Bajaj
    Division of Gastroenterology, Hepatology and Nutrition, Virginia Commonwealth University and McGuire VA Medical Center, Richmond, Virginia 23249, USA
    Gastroenterology 140:478-487.e1. 2011
    ..We evaluated whether performance on a driving simulator improves in patients with MHE after treatment with rifaximin...
  11. ncbi Cognitive performance as a predictor of hepatic encephalopathy in pretransplant patients with cirrhosis receiving psychoactive medications: a prospective study
    Jasmohan S Bajaj
    Division of Gastroenterology, Hepatology, and Nutrition, Virginia Commonwealth University McGuire VA Medical Center, Richmond, VA 23249, USA
    Liver Transpl 18:1179-87. 2012
    ..In conclusion, cognitive tests (particularly the ICT) remain valid predictors of HE in the face of psychiatric diseases and medications. SSRI use is associated with better cognitive performance and a reduced likelihood of developing HE...
  12. ncbi Diagnosis and treatment of minimal hepatic encephalopathy to prevent motor vehicle accidents: a cost-effectiveness analysis
    Jasmohan S Bajaj
    Division of Gastroenterology, Hepatology and Nutrition, Virginia Commonwealth University and McGuire VA Medical Center, Richmond, VA 23249, USA
    Hepatology 55:1164-71. 2012
    ..Conclusion: Detection of MHE, especially using the ICT, and subsequent treatment with lactulose could substantially reduce societal costs by preventing MVAs...
  13. ncbi The multi-dimensional burden of cirrhosis and hepatic encephalopathy on patients and caregivers
    Jasmohan S Bajaj
    Division of Gastroenterology, Hepatology, and Nutrition, Virginia Commonwealth University, McGuire VA Medical Center, Richmond, Virginia 23249, USA
    Am J Gastroenterol 106:1646-53. 2011
    ..The aim was to study the emotional and socioeconomic burden of cirrhosis and HE on patients and informal caregivers...
  14. ncbi Colonic mucosal microbiome differs from stool microbiome in cirrhosis and hepatic encephalopathy and is linked to cognition and inflammation
    Jasmohan S Bajaj
    Division of Gastroenterology, Hepatology and Nutrition, Virginia Commonwealth University, Richmond, 23249, USA
    Am J Physiol Gastrointest Liver Physiol 303:G675-85. 2012
    ....
  15. ncbi Modulation of the metabiome by rifaximin in patients with cirrhosis and minimal hepatic encephalopathy
    Jasmohan S Bajaj
    Division of Gastroenterology, Hepatology and Nutrition, Virginia Commonwealth University and McGuire Veterans Affairs Medical Center, Richmond, Virginia, United States of America
    PLoS ONE 8:e60042. 2013
    ..Aim To perform a systems biology analysis of the microbiome, metabolome and cognitive change after rifaximin in MHE...
  16. ncbi Asymmetric dimethylarginine is strongly associated with cognitive dysfunction and brain MR spectroscopic abnormalities in cirrhosis
    Jasmohan S Bajaj
    Division of Gastroenterology, Hepatology and Nutrition, Virginia Commonwealth University and McGuire VA Medical Center, Richmond, VA 23249, USA
    J Hepatol 58:38-44. 2013
    ..We aimed at evaluating the association of ADMA with cognition and brain MR spectroscopy (MRS) in cirrhosis...
  17. ncbi Persistence of cognitive impairment after resolution of overt hepatic encephalopathy
    Jasmohan S Bajaj
    Division of Gastroenterology, Hepatology, and Nutrition, Virginia Commonwealth University and McGuire VA Medical Center, Richmond, Virginia 23249, USA
    Gastroenterology 138:2332-40. 2010
    ..In patients with cirrhosis, hepatic encephalopathy (HE) has acute but reversible as well as chronic components. We investigated the extent of residual cognitive impairment following clinical resolution of overt HE (OHE)...
  18. ncbi Second infections independently increase mortality in hospitalized patients with cirrhosis: the North American consortium for the study of end-stage liver disease (NACSELD) experience
    Jasmohan S Bajaj
    Division of Gastroenterology, Hepatology and Nutrition, Virginia Commonwealth University and McGuire VA Medical Center, Richmond, VA 23249, USA
    Hepatology 56:2328-35. 2012
    ..03) albumin (OR: 0.5), and second infection (OR: 4.42) as significant variables. CONCLUSION: Potentially preventable second infections are predictors of mortality independent of liver disease severity in this multicenter cirrhosis cohort...
  19. ncbi Linkage of gut microbiome with cognition in hepatic encephalopathy
    Jasmohan S Bajaj
    Div of Gastroenterology, Hepatology and Nutrition, Virginia Commonwealth Univ and McGuire VA Medical Ctr, 1201, Broad Rock Blvd, Richmond, VA 23249, USA
    Am J Physiol Gastrointest Liver Physiol 302:G168-75. 2012
    ..Specific bacterial families (Alcaligeneceae, Porphyromonadaceae, Enterobacteriaceae) are strongly associated with cognition and inflammation in HE...
  20. ncbi Modulation of the fecal bile acid profile by gut microbiota in cirrhosis
    Genta Kakiyama
    Division of Gastroenterology, Hepatology and Nutrition, Virginia Commonwealth University and McGuire VA Medical Center, Richmond, VA, United States
    J Hepatol 58:949-55. 2013
    ..We aimed at studying the linkage between fecal BAs and gut microbiota in cirrhosis since this could help understand cirrhosis progression...
  21. ncbi Covert hepatic encephalopathy: not as minimal as you might think
    Matthew R Kappus
    Division of Gastroenterology, Hepatology and Nutrition, Virginia Commonwealth University and McGuire VA Medical Center, Richmond, Virginia 23249, USA
    Clin Gastroenterol Hepatol 10:1208-19. 2012
    ..Patients with MHE are first managed by excluding other causes of neurocognitive dysfunction. Therapy with gut-specific agents might be effective. We review management strategies and important areas of research for MHE and covert HE...
  22. ncbi Advances in the evaluation and management of minimal hepatic encephalopathy
    Jennifer Y Montgomery
    Virginia Commonwealth University, Richmond, VA 23249, USA
    Curr Gastroenterol Rep 13:26-33. 2011
    ..MHE is a real and growing problem that is epidemic in cirrhosis, and increasing awareness of this condition is necessary for adequate management of these patients...
  23. ncbi Diet and cognition in chronic liver disease
    Toufic Kachaamy
    Division of Gastroenterology, Hepatology and Nutrition, Virginia Commonwealth University and McGuire VA Medical Center, Richmond, Virginia, USA
    Curr Opin Gastroenterol 27:174-9. 2011
    ....
  24. ncbi Assessment of minimal hepatic encephalopathy (with emphasis on computerized psychometric tests)
    Matthew R Kappus
    Division of Gastroenterology, Hepatology and Nutrition, McGuire VA Medical Center, Virginia Commonwealth University, 1201 Broad Rock Boulevard, Richmond, VA 23249, USA
    Clin Liver Dis 16:43-55. 2012
    ..Neurophysiologic tests also provide useful information. The diagnosis of MHE is an important issue for clinicians and patients alike. Testing strategies depend on the normative data available, patient comfort, and local expertise...
  25. ncbi Increased rates of early adverse reaction to azathioprine in patients with Crohn's disease compared to autoimmune hepatitis: a tertiary referral center experience
    Jasmohan S Bajaj
    Division of Gastroenterology and Hepatology; Division of Allergy and Immunology, Department of Medicine, Digestive Disease Center, Froedtert Memorial Lutheran Hospital, Medical College of Wisconsin, Milwaukee, Wisconsin, USA
    Am J Gastroenterol 100:1121-5. 2005
    ..CONCLUSIONS: CD patients represent a unique subgroup at increased risk of EAR to azathioprine. Mechanisms behind these reactions need to be further defined...
  26. ncbi Effect of obstructive sleep apnea on the sleep architecture in cirrhosis
    Matthew R Kappus
    Division of Gastroenterology, Hepatology, and Nutrition, Virginia Commonwealth University and McGuire VA Medical Center, Richmond, VA 23249, USA
    J Clin Sleep Med 9:247-51. 2013
    ..We aimed to evaluate the additional effect of cirrhosis with and without prior HE on the sleep architecture and perceived sleep disturbances of OSA patients...
  27. ncbi Should a radiological diagnosis of hepatocellular carcinoma be routinely confirmed by a biopsy? No
    Douglas M Heuman
    Division of Gastroenterology, Hepatology and Nutrition, Virginia Commonwealth University and Hunter Holmes McGuire Department of Veterans Affairs Medical Center, Richmond, VA 23249, USA
    Eur J Intern Med 23:37-9. 2012
    ..Biopsy for assessment of tumor molecular markers is promising but remains investigational. When diagnosis of HCC is clinically evident by imaging criteria, tumor biopsy should not be required prior to initiating treatment...