Research Topics
| Najib T AyasSummaryCountry: USA Publications
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Detail Information
Publications
A prospective study of sleep duration and coronary heart disease in womenNajib T Ayas
Division of Pulmonary Medicine, Department of Medicine, Vancouver General Hospital, 2775 Heather St, Vancouver, British Columbia, Canada V5Z 3J5
Arch Intern Med 163:205-9. 2003..The objective of this study was to determine whether decreased sleep duration (from self-reports) is associated with an increased risk of coronary events...
Auto-titrating versus standard continuous positive airway pressure for the treatment of obstructive sleep apnea: results of a meta-analysisNajib T Ayas
Department of Medicine, University of British Colombia
Sleep 27:249-53. 2004....
The impact of a telemedicine monitoring system on positive airway pressure adherence in patients with obstructive sleep apnea: a randomized controlled trialNurit Fox
Sleep Disorders Program, University of British Columbia Hospital, Vancouver, British Columbia, Canada
Sleep 35:477-81. 2012..Although PAP is a highly efficacious treatment, adherence to PAP is still a substantial clinical problem. The objective of this study was to determine whether PAP adherence can be improved with a telemedicine monitoring system...
Epidemiology, risk factors, and consequences of obstructive sleep apnea and short sleep durationNabil M Al Lawati
Respiratory Division, Department of Medicine, University of British Columbia, Vancouver, BC, Canada
Prog Cardiovasc Dis 51:285-93. 2009..Sleep loss may have long-term health consequences and may lead to premature death, cardiovascular disease, and the development of diabetes...
The impact of CPAP on cardiovascular biomarkers in minimally symptomatic patients with obstructive sleep apnea: a pilot feasibility randomized crossover trialVikram R Comondore
Department of Medicine, University of British Columbia, Vancouver, BC, Canada
Lung 187:17-22. 2009..In this pilot crossover study, we assessed (1) the feasibility of using CPAP in a group of minimally symptomatic patients with OSA, assessed through patient compliance and (2) CPAP therapy's effect on biomarkers in these patients...
The economic impact of obstructive sleep apneaNayef AlGhanim
Department of Medicine, University of British Columbia, and Respiratory Division, Vancouver General Hospital, British Columbia, Canada
Lung 186:7-12. 2008..Governments, transportation agencies, industry, and insurance companies need to be better informed concerning the economic impact of untreated OSA and the benefits of therapy...
Organizational and safety culture in Canadian intensive care units: relationship to size of intensive care unit and physician management modelPeter M Dodek
Center for Health Evaluation and Outcome Sciences and Division of Critical Care Medicine, Providence Health Care and University of British Columbia, Vancouver, British Columbia, Canada V6Z 1Y6
J Crit Care 27:11-7. 2012....
To sleep, perchance to dip: obstructive sleep apnea, blood pressure, and cardiovascular diseaseNabil M Al Lawati
Respiratory Division, Department of Medicine, Sleep Disorders Program, University of British Columbia, Vancouver, Canada
Sleep 31:772-3. 2008
Restricting resident work hours: the good, the bad, and the uglyAdam Peets
Division of Critical Care Medicine, Department of Medicine, University of British Columbia, Vancouver, BC
Crit Care Med 40:960-6. 2012..The purpose of this review is to summarize the literature regarding resident work hours in the intensive care unit, focusing on the potential positive and negative impacts of work hour limits...
Diagnosis and initial management of obstructive sleep apnea without polysomnography: a randomized validation studyAlan T Mulgrew
University of British Columbia and Vancouver Coastal Health Research Institute, Vancouver, British Columbia, Canada
Ann Intern Med 146:157-66. 2007..Polysomnography (PSG), despite limited availability and high cost, is currently recommended for diagnosis of obstructive sleep apnea and titration of effective continuous positive airway pressure (CPAP)...
Pneumothorax after insertion of central venous catheters in the intensive care unit: association with month of year and week of monthNajib T Ayas
Program in Critical Care Medicine, Providence Health Care, Vancouver, British Columbia, Canada
Qual Saf Health Care 16:252-5. 2007....
The impact of housestaff fatigue on occupational and patient safetyScot A Mountain
The Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada
Lung 185:203-9. 2007..We believe it is critical to understand the potential adverse consequences of housestaff fatigue to optimize shift schedules and reduce risks to both staff and patients...
Exogenous pulmonary surfactant for the treatment of adult patients with acute respiratory distress syndrome: results of a meta-analysisWarren J Davidson
Department of Medicine University of British Columbia, Vancouver, British Columbia, Canada
Crit Care 10:R41. 2006..The purpose of this study was to perform a systematic review and meta-analysis of exogenous surfactant administration to assess whether this therapy may be useful in adult patients with acute respiratory distress syndrome...
The impact of daily sleep duration on health: a review of the literatureGonzalo G Alvarez
University of British Columbia and Vancouver General Hospital, Vancouver, BC, Canada V5Z 3J5
Prog Cardiovasc Nurs 19:56-9. 2004..Although the data are not definitive, these studies suggest that sleep should not be considered a luxury, but an important component of a healthful lifestyle...
Continuous positive airway pressure therapy for treating sleepiness in a diverse population with obstructive sleep apnea: results of a meta-analysisSanjay R Patel
Division of Pulmonary Medicine, Brigham and Women's Hospital, Boston, Mass, USA
Arch Intern Med 163:565-71. 2003..Patients with more severe apnea and sleepiness seem to benefit the most...
Cost-effectiveness of continuous positive airway pressure therapy for moderate to severe obstructive sleep apnea/hypopneaNajib T Ayas
Department of Medicine and Division of Respiratory Medicine, University of British Columbia, Vancouver, BC, Canada
Arch Intern Med 166:977-84. 2006..CONCLUSION: When quality of life, costs of therapy, and MVC outcomes are considered, CPAP therapy for patients with OSAH is economically attractive...
A prospective study of sleep duration and mortality risk in womenSanjay R Patel
Division of Sleep Medicine, Department of Medicine, Brigham and Women s Hospital, Boston, Mass 02115, USA
Sleep 27:440-4. 2004..However, recent studies suggest the risk of death is lower in those sleeping 7 hours. We prospectively examined the association between sleep duration and mortality in women to better understand the effect of sleep duration on health...
Using a wrist-worn device based on peripheral arterial tonometry to diagnose obstructive sleep apnea: in-laboratory and ambulatory validationStephen D Pittman
Division of Sleep Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115-5817, USA
Sleep 27:923-33. 2004..The device can be used with a low failure rate for single use in the lab and home for self-administered testing...
Depression and sleep-related symptoms in an adult, indigenous, North American populationColleen L Froese
Department of Psychiatry, University British Columbia, Vancouver, BC
J Clin Sleep Med 4:356-61. 2008..The purposes of this study were to assess (1) the prevalence of sleep symptoms and (2) the relationships between symptoms and depression in this population...
Extended work shifts and the risk of motor vehicle crashes among internsLaura K Barger
Division of Sleep Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA
N Engl J Med 352:125-34. 2005..These results have implications for medical residency programs, which routinely schedule physicians to work more than 24 consecutive hours...
Effective implementation of work-hour limits and systemic improvementsChristopher P Landrigan
Department of Medicine, Brigham and Women s Hospital, Boston, USA
Jt Comm J Qual Patient Saf 33:19-29. 2007..Implementation of evidence-based work-hour limits, scientifically designed work schedules, and infrastructural changes, such as the development of standardized handoff systems, are urgently needed...
Effects of health care provider work hours and sleep deprivation on safety and performanceSteven W Lockley
Department of Medicine, Brigham and Women s Hospital, Boston, USA
Jt Comm J Qual Patient Saf 33:7-18. 2007..To reduce the unacceptably high rate of preventable fatigue-related medical error and injuries among health care workers, the United States must establish and enforce safe work-hour limits...
Continuous positive airway pressure therapy for obstructive sleep apnea syndrome: do the dollars make sense?Najib T Ayas
Sleep 28:1211-3. 2005
Nasal pressure recordings to detect obstructive sleep apneaFernanda Ribeiro de Almeida
Division of Orthodontics, Department of Oral Health Sciences, Faculty of Dentistry, The University of British Columbia, 2199 Wesbrook Mall, Vancouver, BC, Canada, V6T 1Z3
Sleep Breath 10:62-9. 2006..However, after correction of the bias, the SleepCheck had reasonable accuracy with an AUC, sensitivity, and specificity similar to other ambulatory type 4 devices currently available...
The public health and safety consequences of sleep disordersKrista Sigurdson
Sleep Disorders Program, UBC Hospital, 2211 Westbrook Mall, Vancouver, BC V6T 2B5, Canada
Can J Physiol Pharmacol 85:179-83. 2007..Finally, we will review data that illustrate the potential adverse patient and occupational safety impacts of the extreme work schedules of housestaff (physicians in training)...
A prospective study of self-reported sleep duration and incident diabetes in womenNajib T Ayas
Division of Sleep Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, USA
Diabetes Care 26:380-4. 2003..Sleep restriction may be an independent risk factor for developing symptomatic diabetes...
Impact of extended-duration shifts on medical errors, adverse events, and attentional failuresLaura K Barger
Division of Sleep Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America
PLoS Med 3:e487. 2006..These results have important public policy implications for postgraduate medical education...
Assessment of a wrist-worn device in the detection of obstructive sleep apneaNajib T Ayas
Department of Medicine, Brigham and Women's Hospital, Division of Sleep Medicine, Harvard Medical School, Boston, MA 02115, USA
Sleep Med 4:435-42. 2003..6/71.4, 93.3/73.3, 90.9/84.2, and 83.3/91.7, respectively. CONCLUSIONS: The Watch_PAT is a device that can detect OSA with reasonable accuracy. Thus, the Watch_PAT may be a useful method to diagnose OSA...
