Najib T Ayas

Summary

Country: USA

Publications

  1. ncbi A prospective study of sleep duration and coronary heart disease in women
    Najib T Ayas
    Division of Pulmonary Medicine, Department of Medicine, Vancouver General Hospital, 2775 Heather St, Vancouver, British Columbia, Canada V5Z 3J5
    Arch Intern Med 163:205-9. 2003
  2. ncbi Auto-titrating versus standard continuous positive airway pressure for the treatment of obstructive sleep apnea: results of a meta-analysis
    Najib T Ayas
    Department of Medicine, University of British Colombia
    Sleep 27:249-53. 2004
  3. pmc The impact of a telemedicine monitoring system on positive airway pressure adherence in patients with obstructive sleep apnea: a randomized controlled trial
    Nurit Fox
    Sleep Disorders Program, University of British Columbia Hospital, Vancouver, British Columbia, Canada
    Sleep 35:477-81. 2012
  4. doi Epidemiology, risk factors, and consequences of obstructive sleep apnea and short sleep duration
    Nabil M Al Lawati
    Respiratory Division, Department of Medicine, University of British Columbia, Vancouver, BC, Canada
    Prog Cardiovasc Dis 51:285-93. 2009
  5. doi The impact of CPAP on cardiovascular biomarkers in minimally symptomatic patients with obstructive sleep apnea: a pilot feasibility randomized crossover trial
    Vikram R Comondore
    Department of Medicine, University of British Columbia, Vancouver, BC, Canada
    Lung 187:17-22. 2009
  6. ncbi New frontiers in obstructive sleep apnoea
    Najib T Ayas
    Department of Medicine, Faculty of Medicine, University of British Columbia, Vancouver, Canada
    Clin Sci (Lond) 127:209-16. 2014
  7. ncbi The economic impact of obstructive sleep apnea
    Nayef AlGhanim
    Department of Medicine, University of British Columbia, and Respiratory Division, Vancouver General Hospital, British Columbia, Canada
    Lung 186:7-12. 2008
  8. doi Organizational and safety culture in Canadian intensive care units: relationship to size of intensive care unit and physician management model
    Peter M Dodek
    Center for Health Evaluation and Outcome Sciences and Division of Critical Care Medicine, Providence Health Care and University of British Columbia, Vancouver, British Columbia, Canada V6Z 1Y6
    J Crit Care 27:11-7. 2012
  9. pmc To sleep, perchance to dip: obstructive sleep apnea, blood pressure, and cardiovascular disease
    Nabil M Al Lawati
    Respiratory Division, Department of Medicine, Sleep Disorders Program, University of British Columbia, Vancouver, Canada
    Sleep 31:772-3. 2008
  10. doi Dynamic cerebral autoregulation during and following acute hypoxia: role of carbon dioxide
    Jordan S Querido
    Faculty of Medicine, University of British Columbia Vancouver, Vancouver, British Columbia, Canada
    J Appl Physiol (1985) 114:1183-90. 2013

Collaborators

Detail Information

Publications30

  1. ncbi A prospective study of sleep duration and coronary heart disease in women
    Najib T Ayas
    Division of Pulmonary Medicine, Department of Medicine, Vancouver General Hospital, 2775 Heather St, Vancouver, British Columbia, Canada V5Z 3J5
    Arch Intern Med 163:205-9. 2003
    ..The objective of this study was to determine whether decreased sleep duration (from self-reports) is associated with an increased risk of coronary events...
  2. ncbi Auto-titrating versus standard continuous positive airway pressure for the treatment of obstructive sleep apnea: results of a meta-analysis
    Najib T Ayas
    Department of Medicine, University of British Colombia
    Sleep 27:249-53. 2004
    ....
  3. pmc The impact of a telemedicine monitoring system on positive airway pressure adherence in patients with obstructive sleep apnea: a randomized controlled trial
    Nurit Fox
    Sleep Disorders Program, University of British Columbia Hospital, Vancouver, British Columbia, Canada
    Sleep 35:477-81. 2012
    ..Although PAP is a highly efficacious treatment, adherence to PAP is still a substantial clinical problem. The objective of this study was to determine whether PAP adherence can be improved with a telemedicine monitoring system...
  4. doi Epidemiology, risk factors, and consequences of obstructive sleep apnea and short sleep duration
    Nabil M Al Lawati
    Respiratory Division, Department of Medicine, University of British Columbia, Vancouver, BC, Canada
    Prog Cardiovasc Dis 51:285-93. 2009
    ..Sleep loss may have long-term health consequences and may lead to premature death, cardiovascular disease, and the development of diabetes...
  5. doi The impact of CPAP on cardiovascular biomarkers in minimally symptomatic patients with obstructive sleep apnea: a pilot feasibility randomized crossover trial
    Vikram R Comondore
    Department of Medicine, University of British Columbia, Vancouver, BC, Canada
    Lung 187:17-22. 2009
    ..In this pilot crossover study, we assessed (1) the feasibility of using CPAP in a group of minimally symptomatic patients with OSA, assessed through patient compliance and (2) CPAP therapy's effect on biomarkers in these patients...
  6. ncbi New frontiers in obstructive sleep apnoea
    Najib T Ayas
    Department of Medicine, Faculty of Medicine, University of British Columbia, Vancouver, Canada
    Clin Sci (Lond) 127:209-16. 2014
    ..Finally, the section on cardiovascular biomarkers reviews the evidence supporting the use of these biomarkers to both measure some of the negative consequences of OSA, as well as the potential benefits of OSA therapies. ..
  7. ncbi The economic impact of obstructive sleep apnea
    Nayef AlGhanim
    Department of Medicine, University of British Columbia, and Respiratory Division, Vancouver General Hospital, British Columbia, Canada
    Lung 186:7-12. 2008
    ..Governments, transportation agencies, industry, and insurance companies need to be better informed concerning the economic impact of untreated OSA and the benefits of therapy...
  8. doi Organizational and safety culture in Canadian intensive care units: relationship to size of intensive care unit and physician management model
    Peter M Dodek
    Center for Health Evaluation and Outcome Sciences and Division of Critical Care Medicine, Providence Health Care and University of British Columbia, Vancouver, British Columbia, Canada V6Z 1Y6
    J Crit Care 27:11-7. 2012
    ....
  9. pmc To sleep, perchance to dip: obstructive sleep apnea, blood pressure, and cardiovascular disease
    Nabil M Al Lawati
    Respiratory Division, Department of Medicine, Sleep Disorders Program, University of British Columbia, Vancouver, Canada
    Sleep 31:772-3. 2008
  10. doi Dynamic cerebral autoregulation during and following acute hypoxia: role of carbon dioxide
    Jordan S Querido
    Faculty of Medicine, University of British Columbia Vancouver, Vancouver, British Columbia, Canada
    J Appl Physiol (1985) 114:1183-90. 2013
    ..05). Our results demonstrate that dCA impairment in isocapnic hypoxia can be prevented with hypocapnia, and highlight the integrated nature of hypoxic cerebrovascular control, which is under strong CO2 influence...
  11. doi Restricting resident work hours: the good, the bad, and the ugly
    Adam Peets
    Division of Critical Care Medicine, Department of Medicine, University of British Columbia, Vancouver, BC
    Crit Care Med 40:960-6. 2012
    ..The purpose of this review is to summarize the literature regarding resident work hours in the intensive care unit, focusing on the potential positive and negative impacts of work hour limits...
  12. ncbi The impact of housestaff fatigue on occupational and patient safety
    Scot A Mountain
    The Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada
    Lung 185:203-9. 2007
    ..We believe it is critical to understand the potential adverse consequences of housestaff fatigue to optimize shift schedules and reduce risks to both staff and patients...
  13. pmc Pneumothorax after insertion of central venous catheters in the intensive care unit: association with month of year and week of month
    Najib T Ayas
    Program in Critical Care Medicine, Providence Health Care, Vancouver, British Columbia, Canada
    Qual Saf Health Care 16:252-5. 2007
    ....
  14. ncbi Diagnosis and initial management of obstructive sleep apnea without polysomnography: a randomized validation study
    Alan T Mulgrew
    University of British Columbia and Vancouver Coastal Health Research Institute, Vancouver, British Columbia, Canada
    Ann Intern Med 146:157-66. 2007
    ..Polysomnography (PSG), despite limited availability and high cost, is currently recommended for diagnosis of obstructive sleep apnea and titration of effective continuous positive airway pressure (CPAP)...
  15. pmc Exogenous pulmonary surfactant for the treatment of adult patients with acute respiratory distress syndrome: results of a meta-analysis
    Warren J Davidson
    Department of Medicine University of British Columbia, Vancouver, British Columbia, Canada
    Crit Care 10:R41. 2006
    ..The purpose of this study was to perform a systematic review and meta-analysis of exogenous surfactant administration to assess whether this therapy may be useful in adult patients with acute respiratory distress syndrome...
  16. ncbi The impact of daily sleep duration on health: a review of the literature
    Gonzalo G Alvarez
    University of British Columbia and Vancouver General Hospital, Vancouver, BC, Canada V5Z 3J5
    Prog Cardiovasc Nurs 19:56-9. 2004
    ..Although the data are not definitive, these studies suggest that sleep should not be considered a luxury, but an important component of a healthful lifestyle...
  17. ncbi Continuous positive airway pressure therapy for treating sleepiness in a diverse population with obstructive sleep apnea: results of a meta-analysis
    Sanjay R Patel
    Division of Pulmonary Medicine, Brigham and Women s Hospital, Boston, Mass, USA
    Arch Intern Med 163:565-71. 2003
    ..Since the publication of these reviews, several randomized controlled trials have been reported. We, therefore, performed a meta-analysis to assess the effect of CPAP on subjective and objective sleepiness...
  18. pmc Impact of extended-duration shifts on medical errors, adverse events, and attentional failures
    Laura K Barger
    Division of Sleep Medicine, Department of Medicine, Brigham and Women s Hospital, Boston, Massachusetts, United States of America
    PLoS Med 3:e487. 2006
    ..Our current study assessed whether extended-duration shifts worked by interns are associated with significant medical errors, adverse events, and attentional failures in a diverse population of interns across the United States...
  19. pmc Using a wrist-worn device based on peripheral arterial tonometry to diagnose obstructive sleep apnea: in-laboratory and ambulatory validation
    Stephen D Pittman
    Division of Sleep Medicine, Department of Medicine, Brigham and Women s Hospital, Boston, MA 02115 5817, USA
    Sleep 27:923-33. 2004
    ..To assess the accuracy of a wrist-worn device (Watch_PAT 100) to diagnose obstructive sleep apnea in the home...
  20. ncbi A prospective study of self-reported sleep duration and incident diabetes in women
    Najib T Ayas
    Division of Sleep Medicine, Department of Medicine, Brigham and Women s Hospital, Boston, USA
    Diabetes Care 26:380-4. 2003
    ..Sleep restriction may be an independent risk factor for developing symptomatic diabetes...
  21. ncbi Extended work shifts and the risk of motor vehicle crashes among interns
    Laura K Barger
    Division of Sleep Medicine, Department of Medicine, Brigham and Women s Hospital, Boston, MA 02115, USA
    N Engl J Med 352:125-34. 2005
    ..Long work hours and work shifts of an extended duration (> or =24 hours) remain a hallmark of medical education in the United States. Yet their effect on health and safety has not been evaluated with the use of validated measures...
  22. ncbi Continuous positive airway pressure therapy for obstructive sleep apnea syndrome: do the dollars make sense?
    Najib T Ayas
    Sleep 28:1211-3. 2005
  23. ncbi Assessment of a wrist-worn device in the detection of obstructive sleep apnea
    Najib T Ayas
    Department of Medicine, Brigham and Women s Hospital, Division of Sleep Medicine, Harvard Medical School, Boston, MA 02115, USA
    Sleep Med 4:435-42. 2003
    ..To assess the accuracy of a wrist-worn device (Watch_PAT100) to diagnose obstructive sleep apnea (OSA)...
  24. pmc Depression and sleep-related symptoms in an adult, indigenous, North American population
    Colleen L Froese
    Department of Psychiatry, University British Columbia, Vancouver, BC
    J Clin Sleep Med 4:356-61. 2008
    ..The purposes of this study were to assess (1) the prevalence of sleep symptoms and (2) the relationships between symptoms and depression in this population...
  25. ncbi Nasal pressure recordings to detect obstructive sleep apnea
    Fernanda Ribeiro de Almeida
    Division of Orthodontics, Department of Oral Health Sciences, Faculty of Dentistry, The University of British Columbia, 2199 Wesbrook Mall, Vancouver, BC, Canada, V6T 1Z3
    Sleep Breath 10:62-9. 2006
    ..However, after correction of the bias, the SleepCheck had reasonable accuracy with an AUC, sensitivity, and specificity similar to other ambulatory type 4 devices currently available...
  26. ncbi Effective implementation of work-hour limits and systemic improvements
    Christopher P Landrigan
    Department of Medicine, Brigham and Women s Hospital, Boston, USA
    Jt Comm J Qual Patient Saf 33:19-29. 2007
    ..Sleep deprivation, ubiquitous among nurses and physicians, recently has been shown to greatly increase rates of serious medical errors and occupational injuries among health care workers in the United States...
  27. ncbi Effects of health care provider work hours and sleep deprivation on safety and performance
    Steven W Lockley
    Department of Medicine, Brigham and Women s Hospital, Boston, USA
    Jt Comm J Qual Patient Saf 33:7-18. 2007
    ..They also report making 300% more fatigue-related medical errors that lead to a patient's death...
  28. ncbi Cost-effectiveness of continuous positive airway pressure therapy for moderate to severe obstructive sleep apnea/hypopnea
    Najib T Ayas
    Department of Medicine and Division of Respiratory Medicine, University of British Columbia, Vancouver, BC, Canada
    Arch Intern Med 166:977-84. 2006
    ..Common first-line therapy for OSAH is continuous positive airway pressure (CPAP). We assessed the cost-effectiveness of CPAP therapy vs none for the treatment of OSAH...
  29. ncbi The public health and safety consequences of sleep disorders
    Krista Sigurdson
    Sleep Disorders Program, UBC Hospital, 2211 Westbrook Mall, Vancouver, BC V6T 2B5, Canada
    Can J Physiol Pharmacol 85:179-83. 2007
    ..Finally, we will review data that illustrate the potential adverse patient and occupational safety impacts of the extreme work schedules of housestaff (physicians in training)...
  30. ncbi A prospective study of sleep duration and mortality risk in women
    Sanjay R Patel
    Division of Sleep Medicine, Department of Medicine, Brigham and Women s Hospital, Boston, Mass 02115, USA
    Sleep 27:440-4. 2004
    ..However, recent studies suggest the risk of death is lower in those sleeping 7 hours. We prospectively examined the association between sleep duration and mortality in women to better understand the effect of sleep duration on health...