Research Topics
| Leslee J ShawSummaryAffiliation: Atlanta Cardiovascular Research Institute Country: USA Publications
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Publications
Cost effectiveness of screening for cardiovascular disease with measures of coronary calciumLeslee J Shaw
Atlanta Cardiovascular Research Institute, GA 30342, USA
Prog Cardiovasc Dis 46:171-84. 2003....
Prognostic value of gated myocardial perfusion SPECTLeslee J Shaw
Atlanta Cardiovascular Research Institute, Atlanta, GA 30342, USA
J Nucl Cardiol 11:171-85. 2004
Prognostic value of normal exercise and adenosine (99m)Tc-tetrofosmin SPECT imaging: results from the multicenter registry of 4,728 patientsLeslee J Shaw
Atlanta Cardiovascular Research Institute, Atlanta, Georgia 30342, USA
J Nucl Med 44:134-9. 2003..A total of 4,728 consecutively tested patients who underwent stress (99m)Tc-tetrofosmin SPECT at 5 U.S. hospitals were included in this series...
Impact of gender on risk stratification by exercise and dobutamine stress echocardiography: long-term mortality in 4234 women and 6898 menLeslee J Shaw
Cardiovascular Research Institute, 5665 Peachtree Dunwoody Road, Atlanta, GA, USA
Eur Heart J 26:447-56. 2005..The aim of this study was to examine 5-year mortality in 4234 women and 6898 men undergoing exercise or dobutamine stress echocardiography at three hospitals...
Induced cardiovascular procedural costs and resource consumption patterns after coronary artery calcium screening: results from the EISNER (Early Identification of Subclinical Atherosclerosis by Noninvasive Imaging Research) studyLeslee J Shaw
Emory University School of Medicine, Atlanta, Georgia, USA
J Am Coll Cardiol 54:1258-67. 2009..We prospectively evaluated procedural costs and resource consumption patterns in the EISNER (Early Identification of Subclinical Atherosclerosis by Noninvasive Imaging Research) study after coronary calcium (CAC) measurements...
Prognostic accuracy of B-natriuretic peptide measurements and coronary artery calcium in asymptomatic subjects (from the Early Identification of Subclinical Atherosclerosis by Noninvasive Imaging Research [EISNER] study)Leslee J Shaw
Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA
Am J Cardiol 104:1245-50. 2009..4% and 35.7% of CV events in patients with hypertension and in elderly patients beyond the Framingham risk score. In conclusion, BNP and CAC are independently predictive of CV events...
Importance of socioeconomic status as a predictor of cardiovascular outcome and costs of care in women with suspected myocardial ischemia. Results from the National Institutes of Health, National Heart, Lung and Blood Institute-sponsored Women's Ischemia Leslee J Shaw
Division of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia 30306, USA
J Womens Health (Larchmt) 17:1081-92. 2008..For women, who are more likely to live in poverty, defining the clinical and economic impact of socioeconomic factors may aid in defining redistributive policies to improve healthcare quality...
Coronary artery calcium to predict all-cause mortality in elderly men and womenPaolo Raggi
Division of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA
J Am Coll Cardiol 52:17-23. 2008..We sought to study the prognostic utility of coronary artery calcium (CAC) in the elderly...
Baseline stress myocardial perfusion imaging results and outcomes in patients with stable ischemic heart disease randomized to optimal medical therapy with or without percutaneous coronary interventionLeslee J Shaw
Emory University School of Medicine, Atlanta, GA 30306, USA
Am Heart J 164:243-50. 2012..The current post hoc substudy analysis examined the relationship between baseline stress myocardial ischemia and clinical outcomes based on randomized treatment assignment...
Impact of ethnicity and gender differences on angiographic coronary artery disease prevalence and in-hospital mortality in the American College of Cardiology-National Cardiovascular Data RegistryLeslee J Shaw
Emory Program in Cardiovascular Outcomes Research and Epidemiology, 1256 Briarcliff Rd NE, Suite 1 N, Emory University School of Medicine, Atlanta, GA 30306, USA
Circulation 117:1787-801. 2008..Although populations referred for coronary angiography are increasingly diverse, there is limited information on coronary artery disease (CAD) prevalence and in-hospital mortality other than for predominately white male patients...
Improved near-term coronary artery disease risk classification with gated stress myocardial perfusion SPECTLeslee J Shaw
Emory University School of Medicine, Atlanta, Georgia, USA
JACC Cardiovasc Imaging 3:1139-48. 2010..We compared analytical approaches to estimate the added value of myocardial perfusion single-photon emission computed tomography (MPS) variables in estimating coronary artery disease (CAD) outcomes...
Prognostic value of number and site of calcified coronary lesions compared with the total scoreMarcus Williams
Emory University School of Medicine, Atlanta, Georgia 30306, USA
JACC Cardiovasc Imaging 1:61-9. 2008..This study sought to evaluate the long-term prognostic value of the number and sites of calcified coronary lesions and to compare the accuracy of number of calcified lesions with the extent of total calcium score...
Coronary computed tomographic angiography as a gatekeeper to invasive diagnostic and surgical procedures: results from the multicenter CONFIRM (Coronary CT Angiography Evaluation for Clinical Outcomes: an International Multicenter) registryLeslee J Shaw
Department of Medicine, Emory University School of Medicine, Atlanta, GA, USA
J Am Coll Cardiol 60:2103-14. 2012..This study sought to examine patterns of follow-up invasive coronary angiography (ICA) and revascularization (REV) after coronary computed tomography angiography (CCTA)...
Sex differences in mortality associated with computed tomographic angiographic measurements of obstructive and nonobstructive coronary artery disease: an exploratory analysisLeslee J Shaw
Emory University, 1256 Briarcliff Road NE, Atlanta, GA 30306, USA
Circ Cardiovasc Imaging 3:473-81. 2010..Limited data are available to explore sex differences in prognosis with coronary computed tomographic angiographic (CCTA) measurements of CAD including novel nonobstructive plaque extent...
Imaging for preventionLeslee J Shaw
Emory University School of Medicine, Atlanta, GA 30324, USA
Med Clin North Am 96:103-12. 2012....
Nomograms for estimating coronary artery disease prognosis with gated stress myocardial perfusion SPECTLeslee J Shaw
Emory Clinical Cardiovascular Research Institute, Emory University School of Medicine, 1462 Clifton Rd NE, Room 530, Atlanta, GA 30306, USA
J Nucl Cardiol 19:43-52. 2012..Nomograms can be useful tools for estimating coronary artery disease (CAD) risk. We sought to devise risk-based nomograms for stress myocardial perfusion SPECT to include measures of % ischemic myocardium and left ventricular function...
Combined impact of age and estimated glomerular filtration rate on in-hospital mortality after percutaneous coronary intervention for acute myocardial infarction (from the American College of Cardiology National Cardiovascular Data Registry)Francesca Cardarelli
Division of Cardiology, Emory University, Atlanta, GA, USA
Am J Cardiol 103:766-71. 2009....
Prognosis by coronary computed tomographic angiography: matched comparison with myocardial perfusion single-photon emission computed tomographyLeslee J Shaw
Department of Medicine, Division of Cardiology, Emory University School of Medicine, Atlanta, GA 30306, USA
J Cardiovasc Comput Tomogr 2:93-101. 2008..The aim of this report was to compare all-cause death rates for 7 CTA subsets, using the Duke prognostic index, compared with percentage of ischemic myocardium by MPS...
Depression, the metabolic syndrome and cardiovascular riskViola Vaccarino
Division of Cardiology, Department of Medicine, Emory University School of Medicine, 1256 Briarcliff Road NE, Suite 1 North, Atlanta, GA 30306, USA
Psychosom Med 70:40-8. 2008..The relationship between depression and the metabolic syndrome is unclear, and whether metabolic syndrome explains the association between depression and cardiovascular disease (CVD) risk is unknown...
Incremental prognostic value of left ventricular function by myocardial ECG-gated FDG PET imaging in patients with ischemic cardiomyopathyCesar A Santana
Department of Radiology, Emory University of School of Medicine, Atlanta, GA 30322, USA
J Nucl Cardiol 11:542-50. 2004....
Cardiovascular imaging research at the crossroadsLeslee J Shaw
Emory University School of Medicine, Atlanta, Georgia 30306, USA
JACC Cardiovasc Imaging 3:316-24. 2010..In this review, we will discuss current health policy of CV imaging as well as the future of CV imaging-based comparative effectiveness research...
Impact of left ventricular function and the extent of ischemia and scar by stress myocardial perfusion imaging on prognosis and therapeutic risk reduction in diabetic patients with coronary artery disease: results from the Bypass Angioplasty RevascularizaLeslee J Shaw
Emory Clinical Cardiovascular Research Institute, Emory University School of Medicine, 1462 Clifton Rd NE, Room 529, Atlanta, GA 30306, USA
J Nucl Cardiol 19:658-69. 2012..Comparisons of post-intervention ischemic burden have not been explored but are relevant to treatment decisions. This study examined differences in 1-year stress myocardial perfusion SPECT (MPS) abnormalities by randomized treatment...
Comparison of prognostic usefulness of coronary artery calcium in men versus women (results from a meta- and pooled analysis estimating all-cause mortality and coronary heart disease death or myocardial infarction)Antonio Bellasi
Emory University School of Medicine, Atlanta, Georgia, USA
Am J Cardiol 100:409-14. 2007..66), suggesting an equivalent ability to risk stratify by gender. In conclusion, this meta- and pooled analysis revealed that CAC screening is equally accurate in stratifying risk in women and men...
Prognostic estimation of coronary artery disease risk with resting perfusion abnormalities and stress ischemia on myocardial perfusion SPECTLeslee J Shaw
Emory University School of Medicine, Atlanta, GA 30306, USA
J Nucl Cardiol 15:762-73. 2008..Prognosis associated with myocardial perfusion single photon emission computed tomography (MPS) abnormalities on the resting scan as it relates to stress ischemia has been incompletely described...
Comparative effectiveness of exercise electrocardiography with or without myocardial perfusion single photon emission computed tomography in women with suspected coronary artery disease: results from the What Is the Optimal Method for Ischemia Evaluation Leslee J Shaw
Emory University, Atlanta, GA 30324, USA
Circulation 124:1239-49. 2011..It remains unclear whether the addition of myocardial perfusion imaging (MPI) to the standard ECG exercise treadmill test (ETT) provides incremental information to improve clinical decision making in women with suspected CAD...
Importance of residual myocardial ischemia after intervention in the genesis of cardiovascular events among patients with chronic coronary artery diseaseLeslee J Shaw
Department of Medicine, Emory University School of Medicine, Atlanta, GA, USA
Curr Cardiol Rep 13:280-6. 2011..This review provides a synopsis of available evidence on serial testing and meaningful thresholds for application of paired rest/stress myocardial perfusion single photon emission computed tomography imaging...
Early menopause predicts angina after myocardial infarctionSusmita Parashar
Division of Cardiology, Department of Medicine, Emory University, Atlanta, GA 30306, USA
Menopause 17:938-45. 2010..It is unknown, however, whether early menopause predicts post-myocardial infarction (MI) angina. We examined whether younger AAM increases risk of post-MI angina...
Epidemiologic guidance with coronary artery calcium scoringPaolo Raggi
Division of Cardiology, Emory University School of Medicine, 1365 Clifton Road NE, AT 504, Atlanta, GA 30322, USA
Curr Cardiol Rep 10:60-6. 2008..Coronary artery calcium screening has become a widely used tool to estimate risk in a variety of categories in the general population and is discussed in this review...
Optimal medical therapy with or without percutaneous coronary intervention to reduce ischemic burden: results from the Clinical Outcomes Utilizing Revascularization and Aggressive Drug Evaluation (COURAGE) trial nuclear substudyLeslee J Shaw
Emory University School of Medicine, Atlanta, GA 30306, USA
Circulation 117:1283-91. 2008....
New insights into ischemic heart disease in womenAntonio Bellasi
Division of Cardiology, Department of Medicine, Emory University, Atlanta, GA 30306, USA
Cleve Clin J Med 74:585-94. 2007..Needed is a strategy for detecting and assessing coronary disease specifically in women. This review highlights recent evidence on sex differences in coronary artery disease...
Depression, inflammation, and incident cardiovascular disease in women with suspected coronary ischemia: the National Heart, Lung, and Blood Institute-sponsored WISE studyViola Vaccarino
Department of Medicine, Division of Cardiology, Emory University School of Medicine, Atlanta, Georgia 30306, USA
J Am Coll Cardiol 50:2044-50. 2007..The purpose of this study was to examine prospectively whether inflammation explains the relationship between depression and cardiovascular disease (CVD)...
Calculation of coronary age using calcium scores in multiple ethnicitiesGopi K R Sirineni
Department of Radiology, Emory University School of Medicine, 1365 Clifton Road NE, AT 504, Atlanta, GA 30322, USA
Int J Cardiovasc Imaging 24:107-11. 2008..This method should allow patients to better understand the prognostic significance of their test results and may ensure a better compliance with preventive regimens...
Phosphorus levels are associated with subclinical atherosclerosis in the general populationStephen J Onufrak
Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, United States
Atherosclerosis 199:424-31. 2008..The aim of our study was to examine the association of serum phosphorus level with carotid atherosclerosis in the general population...
Risk assessment and predictive value of coronary artery disease testingLeslee J Shaw
School of Medicine, Emory University, Atlanta, Georgia 30306, USA
J Nucl Med 50:1296-306. 2009..Despite a high level of evidence, comparative research is not available across modalities that could definitively drive utilization of cardiac imaging modalities...
Functional versus anatomic imaging in patients with suspected coronary artery diseaseLeslee J Shaw
Emory University School of Medicine, Atlanta, GA 30306, USA
Cardiol Clin 27:597-604. 2009..This article reviews the relative value of anatomical versus functional imaging and their complementary role in different clinical scenarios...
Women and ischemic heart disease: evolving knowledgeLeslee J Shaw
Emory Program in Cardiovascular Outcomes Research and Epidemiology, Emory University School of Medicine, Atlanta, Georgia, USA
J Am Coll Cardiol 54:1561-75. 2009..Continued research is indicated to devise therapeutic regimens to improve symptom burden and reduce risk in women with ischemic heart disease...
Prognostic value of cardiac risk factors and coronary artery calcium screening for all-cause mortalityLeslee J Shaw
American Cardiovascular Research Institute, Atlanta, GA, USA
Radiology 228:826-33. 2003..CONCLUSION: This large observational data series shows that coronary calcium provides independent incremental information in addition to traditional risk factors in the prediction of all-cause mortality...
Tracking atherosclerosis regression: a clinical tool in preventive cardiologyAllen Taylor
Walter Reed Army Medical Center, Atlanta, GA, USA
Atherosclerosis 180:1-10. 2005..The current review focuses on the application of these modalities as emerging tools in cardiovascular prevention...
Foreword: cardiovascular disease: diagnostic, prognostic, and measurement paradigms for reducing patient riskD Douglas Miller
Medical College of Georgia School of Medicine, Medical College of Georgia, Augusta, GA, USA
J Cardiovasc Nurs 21:S1. 2006
Coronary artery disease: diagnostic and prognostic models for reducing patient riskD Douglas Miller
Medical College of Georgia School of Medicine, Medical College of Georgia, Augusta, GA 30912, USA
J Cardiovasc Nurs 21:S2-16; quiz S17-9. 2006..Advances in computer technology have made sophisticated devices, such as the gated SPECT, a routine part of cardiology...
Noninvasive cardiac imagingJennifer H Mieres
USA Division of Cardiology, North Shore University Hospital, North Shore Long Island Jewish Health System, Manhasset, New York, USA
Am Fam Physician 75:1219-28. 2007..Although guidelines can help with treating patients, treatment ultimately should be tailored to each person based on clinical judgment of the a priori risk of a cardiac event, symptoms, and the cardiac risk profile...
Long-term prognosis associated with coronary calcification: observations from a registry of 25,253 patientsMatthew J Budoff
Harbor UCLA Los Angeles Biomedical Research Institute, Torrance, California 90502, USA
J Am Coll Cardiol 49:1860-70. 2007....
Value of multislice computed tomography coronary angiography in suspected coronary artery diseaseKhurram Nasir
J Am Coll Cardiol 49:2070-1; author reply 2071. 2007
Value of electrocardiographically gated single-photon emission computed tomographic myocardial perfusion scintigraphy in a cohort of symptomatic postmenopausal womenJennifer H Mieres
New York University School of Medicine, New York, USA
Am J Cardiol 99:1096-9. 2007..001). In conclusion, results of this study indicate high diagnostic and prognostic accuracy for MPS in symptomatic postmenopausal women...
Prognostic value of coronary artery calcium screening in asymptomatic smokers and non-smokersLeslee J Shaw
Cedars Sinai Medical Center, Room 125 4, Taper Building, 8700 Beverly Boulevard, Los Angeles, CA 90048, USA
Eur Heart J 27:968-75. 2006..Limited data are available on the impact of cigarette smoking on the prognostic value of coronary calcium...
Comparison of atherosclerotic calcification burden in persons with the cardiometabolic syndrome and diabetesNathan D Wong
Department of Imaging and Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA
J Cardiometab Syndr 1:90-4. 2006..52-2.90) for CAC and 1.14 (0.91-1.42), 1.03 (0.77-1.37), 1.03 (0.68-1.54), and 1.41 (1.03-1.92) for TAC. Multiple CMS risk factors are associated with increased CAC, but not TAC; DM with CMS has the highest prevalence of CAC and TAC...
Impact of diabetes on the risk stratification using stress single-photon emission computed tomography myocardial perfusion imaging in patients with symptoms suggestive of coronary artery diseaseSatyendra Giri
Nuclear Cardiology Laboratory, Division of Cardiology, Hartford Hospital, and the Department of Medicine and Nuclear Medicine, University of Connecticut School of Medicine, Farmington, CT 06102-5037, USA
Circulation 105:32-40. 2002..Using stress MPI in conjunction with clinical information can provide risk stratification of diabetic patients...
Multidetector computed tomography coronary artery plaque predictors of stress-induced myocardial ischemia by SPECTFay Lin
The Greenberg Division of Cardiology, Weill Medical College of Cornell University, The New York Presbyterian Hospital, New York, NY 10021, United States
Atherosclerosis 197:700-9. 2008..We sought to determine whether anatomic measures of plaque by MDCT predict functional measures of CHD by SPECT and thus, serve as measures of adverse cardiovascular prognosis...
Ethnic differences in the prognostic value of coronary artery calcification for all-cause mortalityKhurram Nasir
Cardiac MRI PET CT Program, Massachusetts General Hospital Boston, Harvard School of Medicine, Boston, Massachusetts, USA
J Am Coll Cardiol 50:953-60. 2007....
Diagnostic strategies for heart disease in women: an update on imaging techniques for optimal managementAmgad N Makaryus
Department of Medicine, Division of Cardiology, North Shore University Hospital, Manhasset, New York, USA
Cardiol Rev 15:279-87. 2007..In this article we review the literature regarding the diagnostic and prognostic evaluation of coronary artery disease in women with respect to imaging...
Prognostic value of multidetector coronary computed tomographic angiography for prediction of all-cause mortalityJames K Min
Greenberg Division of Cardiology, Weill Medical College of Cornell University, New York Presbyterian Hospital, New York, New York 10021, USA
J Am Coll Cardiol 50:1161-70. 2007..The purpose of this study was to examine the association of all-cause death with the coronary computed tomographic angiography (CCTA)-defined extent and severity of coronary artery disease (CAD)...
Risk stratification in patients with remote prior myocardial infarction using rest-stress myocardial perfusion SPECT: prognostic value and impact on referral to early catheterizationMichael J Zellweger
Department of Imaging (Division of Nuclear Medicine, Cedars-Sinai Medical Center, The CSMC Burns and Allen Research Institute, Los Angeles, Calif. 90048, USA
J Nucl Cardiol 9:23-32. 2002..Patients with normal or mildly abnormal scan results or small MI in combination with absent or mild ischemia have a low risk for CD...
Clinical importance of obesity versus the metabolic syndrome in cardiovascular risk in women: a report from the Women's Ischemia Syndrome Evaluation (WISE) studyKevin E Kip
Department of Epidemiology, University of Pittsburgh, Graduate School of Public Health, Pittsburgh, PA 15261, USA
Circulation 109:706-13. 2004..Both are associated with cardiovascular disease (CVD). However, the contribution of obesity to cardiovascular risk, independent of the presence of the metabolic syndrome, remains controversial...
Metabolic syndrome modifies the cardiovascular risk associated with angiographic coronary artery disease in women: a report from the Women's Ischemia Syndrome EvaluationOscar C Marroquin
Cardiovascular Institute, University of Pittsburgh, Pittsburgh, PA, USA
Circulation 109:714-21. 2004..Specifically, the metabolic syndrome was found to be a predictor of 4-year cardiovascular risk only when associated with significant angiographic CAD...
Prognostic value of coronary artery calcium screening in subjects with and without diabetesPaolo Raggi
Section of Cardiology, Tulane University School of Medicine, New Orleans, Louisiana 70112, USA
J Am Coll Cardiol 43:1663-9. 2004..The study was done to determine the interaction of coronary artery calcium and diabetes mellitus for prediction of all-cause death...
Gender-based differences in the prognostic value of coronary calcificationPaolo Raggi
Tulane University School of Medicine, New Orleans, Louisiana 70112, USA
J Womens Health (Larchmt) 13:273-83. 2004..To investigate the use of electron beam tomography (EBT) screening to predict all-cause mortality in a large cohort of asymptomatic women and men...
Prognosis in women with myocardial ischemia in the absence of obstructive coronary disease: results from the National Institutes of Health-National Heart, Lung, and Blood Institute-Sponsored Women's Ischemia Syndrome Evaluation (WISE)B Delia Johnson
Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA
Circulation 109:2993-9. 2004..Further evaluation into the underlying pathophysiology and possible treatment options for women with evidence of myocardial ischemia but without CAD is indicated...
Screening asymptomatic low-risk individuals for coronary heart disease: issues and controversiesLeslee J Shaw
J Nucl Cardiol 11:382-7. 2004
Adenosine sestamibi SPECT post-infarction evaluation (INSPIRE) trial: A randomized, prospective multicenter trial evaluating the role of adenosine Tc-99m sestamibi SPECT for assessing risk and therapeutic outcomes in survivors of acute myocardial infarctiJohn J Mahmarian
The Methodist DeBakey Heart Center and Section of Cardiology, Department of Medicine, Baylor College of Medicine, Houston, TX 77030 2717, USA
J Nucl Cardiol 11:458-69. 2004..Preliminary studies indicate that adenosine myocardial perfusion single photon tomography (SPECT) can safely and accurately stratify patients into low and high risk groups early after acute myocardial infarction (AMI)...
Comparison of risk stratification with pharmacologic and exercise stress myocardial perfusion imaging: a meta-analysisSachin M Navare
Nuclear Cardiology Laboratory of the Henry Low Heart Center, Hartford Hospital, St. Hartford, CT 06102, USA
J Nucl Cardiol 11:551-61. 2004..However, patients undergoing pharmacologic stress studies are at a higher risk for subsequent cardiac events. This is true even for those with normal perfusion imaging results...
Technetium 99m sestamibi myocardial perfusion imaging predicts clinical outcome in the community outpatient setting. The Nuclear Utility in the Community (NUC) StudyGregory S Thomas
Mission Internal Medical Group, Mission Viejo, California 92691, USA
J Am Coll Cardiol 43:213-23. 2004....
Diagnosis of coronary artery disease in womenRita F Redberg
Women's Cardiovascular Services, UCSF National Center for Excellence and School of Medicine, Division of Cardiology, University of California, San Francisco, 94143-0124, USA
Prog Cardiovasc Dis 46:239-58. 2003
The clinical role of stress myocardial perfusion imaging in women with suspected coronary artery diseaseJennifer H Mieres
North Shore University Hospital, Division of Cardiology, 300 Community Drive, Manhasset, NY 11030, USA
Curr Cardiol Rep 6:27-31. 2004..This review discusses the clinical role of stress MPI in the management of women with suspected CAD...
Value of stress myocardial perfusion single photon emission computed tomography in patients with normal resting electrocardiograms: an evaluation of incremental prognostic value and cost-effectivenessRory Hachamovitch
Department of Imaging (Division of Nuclear Medicine, Cedars-Sinai Medical Center, University of California Los Angeles School of Medicine, Los Angeles, Calif 90048, USA
Circulation 105:823-9. 2002..These findings are opposite those of previous studies examining anatomic end points in this same population and thus, if confirmed, have significant implications for patient management...
Myocardial viability testing and impact of revascularization on prognosis in patients with coronary artery disease and left ventricular dysfunction: a meta-analysisKevin C Allman
Concord Hospital, Concord NSW, Australia
J Am Coll Cardiol 39:1151-8. 2002....
A review of electron beam computed tomography: implications for coronary artery disease screeningRita F Redberg
Division of Cardiology, University of California, San Francisco, San Francisco, CA 94143 0124, USA
Prev Cardiol 5:71-8. 2002..Widespread clinical use of EBCT is not recommended, pending data to establish its efficacy in the role of risk factor reduction and prevention of cardiovascular disease...
American Society of Nuclear Cardiology consensus statement: Task Force on Women and Coronary Artery Disease--the role of myocardial perfusion imaging in the clinical evaluation of coronary artery disease in women [correction]Jennifer H Mieres
American Society of Nuclear Cardiology, Bethesda, MD 20814-1699, USA
J Nucl Cardiol 10:95-101. 2003
Adenosine myocardial perfusion single-photon emission computed tomography in women compared with men. Impact of diabetes mellitus on incremental prognostic value and effect on patient managementDaniel S Berman
Department of Imaging, Division of Nuclear Medicine, and CSMC Burns and Allen Research Institute, Cedars Sinai Medical Center, University of California Los Angeles, School of Medicine, Los Angeles, California 90048, USA
J Am Coll Cardiol 41:1125-33. 2003..This study was designed to assess the incremental prognostic value of adenosine stress myocardial perfusion single-photon emission computed tomography (MPS) in women versus men, and to explore the prognostic impact of diabetes mellitus...
Determinants of risk and its temporal variation in patients with normal stress myocardial perfusion scans: what is the warranty period of a normal scan?Rory Hachamovitch
Division of Cardiovascular Medicine, Department of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, USA
J Am Coll Cardiol 41:1329-40. 2003..The aim of this study was to determine the predictors of risk and the temporal characteristics of risk associated with normal myocardial perfusion single photon emission computed tomography (MPS)...
Symptoms, myocardial ischaemia and quality of life in women: results from the NHLBI-sponsored WISE StudyMarian B Olson
Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA
Eur Heart J 24:1506-14. 2003..Our goal was to evaluate health-related quality of life (QOL) in women undergoing angiography for suspected ischaemia...
Progression of coronary calcium on serial electron beam tomographic scanning is greater in patients with future myocardial infarctionPaolo Raggi
Tulane University School of Medicine, New Orleans, Lousiana, USA
Am J Cardiol 92:827-9. 2003..The yearly mean absolute and percent CVS changes in the 45 patients who had a MI were 147 +/- 152 and 47 +/- 50%, respectively, compared with 63 +/- 128 and 26 +/- 32%, respectively (p <0.001, p = 0.01), in patients without events...
The role of myocardial perfusion imaging in special populations: women, diabetics, and heart failureJennifer H Mieres
Division of Cardiology, North Shore University Hospital, Manhasset, NY 11030, USA
Semin Nucl Med 35:52-61. 2005....
Clinical indications for cardiovascular magnetic resonance (CMR): Consensus Panel reportDudley J Pennell
Royal Brompton Hospital, London, UK
J Cardiovasc Magn Reson 6:727-65. 2004
Roles of nuclear cardiology, cardiac computed tomography, and cardiac magnetic resonance: Noninvasive risk stratification and a conceptual framework for the selection of noninvasive imaging tests in patients with known or suspected coronary artery diseaseDaniel S Berman
Department of Imaging and Medicine, Cedars Sinai Medical Center, Burns and Allen Research Institute, Los Angeles, California 90048, USA
J Nucl Med 47:1107-18. 2006..We consider it likely that, with an increased emphasis on prevention and a concomitant aging of the population, many forms of noninvasive cardiac imaging will continue to grow, with nuclear cardiology continuing to grow...
Prognostic value of poststress left ventricular volume and ejection fraction by gated myocardial perfusion SPECT in women and men: gender-related differences in normal limits and outcomesTali Sharir
Department of Imaging, Division of Nuclear Medicine, Cedars-Sinai Medical Center, Los Angeles, Calif. 90048, USA
J Nucl Cardiol 13:495-506. 2006..After separate criteria for abnormal EF and ESV index in women are used, the combination of severe ischemia and abnormal EF or ESV index identifies women at very high risk of cardiac events...
Obesity distribution and reproductive hormone levels in women: a report from the NHLBI-sponsored WISE StudyMarian B Olson
Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
J Womens Health (Larchmt) 15:836-42. 2006..The differing levels by general and central obesity may help explain in part observed epidemiological relationships between obesity and disease...
Incremental cost-effectiveness of exercise echocardiography vs. SPECT imaging for the evaluation of stable chest painLeslee J Shaw
Cedars Sinai Medical Center, David Geffen UCLA School of Medicine, Taper Building, Los Angeles, CA 90048, USA
Eur Heart J 27:2448-58. 2006..The opportunity costs of strategies favouring exercise echocardiography or SPECT imaging have been incompletely evaluated...
Comparative use of radionuclide stress testing, coronary artery calcium scanning, and noninvasive coronary angiography for diagnostic and prognostic cardiac assessmentDaniel S Berman
Department of Imaging and Medicine, Cedars Sinai Medical Center, CSMC Burns and Allen Research Institute, Los Angeles, CA 90048, USA
Semin Nucl Med 37:2-16. 2007....
A multinational study to establish the value of early adenosine technetium-99m sestamibi myocardial perfusion imaging in identifying a low-risk group for early hospital discharge after acute myocardial infarctionJohn J Mahmarian
Methodist DeBakey Heart Center, Department of Cardiology, The Methodist Hospital, Houston, Texas 77030, USA
J Am Coll Cardiol 48:2448-57. 2006....
An initial strategy of intensive medical therapy is comparable to that of coronary revascularization for suppression of scintigraphic ischemia in high-risk but stable survivors of acute myocardial infarctionJohn J Mahmarian
Methodist DeBakey Heart Center, Department of Cardiology, The Methodist Hospital, Houston, Texas 77030, USA
J Am Coll Cardiol 48:2458-67. 2006..The purpose of this study was to determine the relative benefit of intensive medical therapy compared with coronary revascularization for suppressing scintigraphic ischemia...
Anger, hostility, and cardiac symptoms in women with suspected coronary artery disease: the Women's Ischemia Syndrome Evaluation (WISE) StudyDavid S Krantz
Department of Medical and Clinical Psychology, Uniformed Services University of Health Sciences, Bethesda, Maryland 20814, USA
J Womens Health (Larchmt) 15:1214-23. 2006..To determine the relationship of anger and hostility to angiographic coronary artery disease (CAD), symptoms, and functional status among women with suspected CAD...
Cardiovascular disease risk stratification with stress single-photon emission computed tomography technetium-99m tetrofosmin imaging in patients with the metabolic syndrome and diabetes mellitusLeslee J Shaw
Cedars Sinai Medical Center, Los Angeles, California, USA
Am J Cardiol 97:1538-44. 2006..In conclusion, cardiovascular prognosis is affected by the degree of metabolic dysfunction, and stress-induced reductions in myocardial perfusion provide an accurate means for near-term risk stratification...
Diagnostic accuracy of gated Tc-99m sestamibi stress myocardial perfusion SPECT with combined supine and prone acquisitions to detect coronary artery disease in obese and nonobese patientsDaniel S Berman
Department of Imaging, Division of Nuclear Medicine, Burns and Allen Research Institute, Cedars Sinai Medical Center, Los Angeles, Calif 90048, USA
J Nucl Cardiol 13:191-201. 2006..The diagnostic value of gated myocardial perfusion single-photon emission computed tomography (MPS) with combined supine and prone acquisitions to detect coronary artery disease (CAD) in obese and nonobese patients has not been defined...
Role of noninvasive imaging in asymptomatic high-risk patientsLeslee J Shaw
Cedars-Sinai Medical Center and David Geffen School of Medicine at UCLA, Los Angeles, Calif 90048, USA
J Nucl Cardiol 13:156-62. 2006
Role of noninvasive testing in the clinical evaluation of women with suspected coronary artery disease: Consensus statement from the Cardiac Imaging Committee, Council on Clinical Cardiology, and the Cardiovascular Imaging and Intervention Committee, CounJennifer H Mieres
Circulation 111:682-96. 2005....
Ethnic differences in the prognostic value of stress technetium-99m tetrofosmin gated single-photon emission computed tomography myocardial perfusion imagingLeslee J Shaw
Cedars Sinai Medical Center, Los Angeles, California 90048, USA
J Am Coll Cardiol 45:1494-504. 2005..This study was designed to evaluate the differential prognostic value of gated single-photon emission computed tomographic imaging (SPECT) imaging in an ethnically diverse multicenter registry...
Prognostic value of the duke treadmill score in asymptomatic womenMartha Gulati
Department of Preventive Medicine, Rush University Medical Center, Chicago, Illinois, USA
Am J Cardiol 96:369-75. 2005..The role of ST-segment changes and symptoms with stress testing in asymptomatic women does not provide additional prognostic information...
Redefining the low-risk patient with significant atherosclerotic diseaseLeslee J Shaw
J Nucl Cardiol 12:375-7. 2005
Coronary artery calcium as a measure of biologic ageLeslee J Shaw
Cedars Sinai Medical Center, Los Angeles, CA, USA
Atherosclerosis 188:112-9. 2006..Age is assigned a heavy weight in the calculation of the total cardiovascular risk score but often the atherosclerotic disease burden varies from a patient's chronological age...
Insights from the NHLBI-Sponsored Women's Ischemia Syndrome Evaluation (WISE) Study: Part II: gender differences in presentation, diagnosis, and outcome with regard to gender-based pathophysiology of atherosclerosis and macrovascular and microvascular corC Noel Bairey Merz
Division of Cardiology, Department of Medicine, Cedars Sinai Research Institute, Cedars Sinai Medical Center, Los Angeles, California, USA
J Am Coll Cardiol 47:S21-9. 2006..Additionally, innovative cardiovascular imaging techniques will be discussed. Finally, we identify critical areas of further inquiry needed to advance this new gender-specific IHD understanding into improved outcomes for women...
The value of estimated functional capacity in estimating outcome: results from the NHBLI-Sponsored Women's Ischemia Syndrome Evaluation (WISE) StudyLeslee J Shaw
Division of Cardiology, Department of Medicine, Cedars Sinai Research Institute, Cedars Sinai Medical Center, Los Angeles, California 90048, USA
J Am Coll Cardiol 47:S36-43. 2006..Our objective was to determine the prognostic value of estimated metabolic equivalents (METs) based on self-reported functional capacity by the Duke Activity Status Index (DASI) in symptomatic women...
Impact of body mass index on cardiac mortality in patients with known or suspected coronary artery disease undergoing myocardial perfusion single-photon emission computed tomographyXingping Kang
Department of Imaging, Division of Nuclear Medicine, and CSMC Burns and Allen Research Institute, Cedars-Sinai Medical Center, Los Angeles, California 90048, USA
J Am Coll Cardiol 47:1418-26. 2006..In patients with known CAD undergoing MPS, obese and overweight patients were at lower risk of CD over three years than normal weight patients...
Assessing mature technology: what is the effect of high-quality risk stratification evidence with exercise echocardiography and single-photon emission computed tomography imaging?Leslee J Shaw
J Am Coll Cardiol 49:238-9. 2007
