Michael T Pyne

Summary

Affiliation: ARUP Institute for Clinical and Experimental Pathology
Country: USA

Publications

  1. pmc Large-scale analysis of the prevalence and geographic distribution of HIV-1 non-B variants in the United States
    Michael T Pyne
    ARUP Institute for Clinical and Experimental Pathology, Salt Lake City, Utah, USA
    J Clin Microbiol 51:2662-9. 2013
  2. doi request reprint Evaluation of the Roche COBAS AmpliPrep/COBAS TaqMan HCV Test
    Michael T Pyne
    ARUP Institute for Clinical and Experimental Pathology, Salt Lake City, UT 84108, USA
    Diagn Microbiol Infect Dis 77:25-30. 2013
  3. pmc Comparison of three Roche hepatitis B virus viral load assay formats
    Michael T Pyne
    ARUP Institute for Clinical and Experimental Pathology, Salt Lake City, Utah, USA
    J Clin Microbiol 50:2337-42. 2012
  4. doi request reprint Large-scale comparison of Roche Cobas AmpliPrep/Cobas TaqMan and Abbott RealTime HIV assays
    Michael T Pyne
    ARUP Institute for Clinical and Experimental Pathology, 500 Chipeta Way, Salt Lake City, UT 84108, United States
    J Virol Methods 184:106-8. 2012
  5. pmc Evaluation of the Abbott investigational use only realtime HIV-1 assay and comparison to the Roche Amplicor HIV-1 monitor test, version 1.5
    Michael T Pyne
    ARUP Institute for Clinical and Experimental Pathology, Salt Lake City, UT 84108, USA
    J Mol Diagn 11:347-54. 2009
  6. pmc Evaluation of the Abbott investigational use only RealTime hepatitis C virus (HCV) assay and comparison to the Roche TaqMan HCV analyte-specific reagent assay
    Michael T Pyne
    ARUP Institute for Clinical and Experimental Pathology, 500 Chipeta Way, Salt Lake City, UT 84108, USA
    J Clin Microbiol 47:2872-8. 2009
  7. pmc Evaluation of the Roche Cobas AmpliPrep/Cobas TaqMan HIV-1 test and identification of rare polymorphisms potentially affecting assay performance
    Michael T Pyne
    ARUP Institute for Clinical and Experimental Pathology, 500 Chipeta Way, Salt Lake City, UT 84108, USA
    J Clin Microbiol 48:2852-8. 2010

Collaborators

Detail Information

Publications7

  1. pmc Large-scale analysis of the prevalence and geographic distribution of HIV-1 non-B variants in the United States
    Michael T Pyne
    ARUP Institute for Clinical and Experimental Pathology, Salt Lake City, Utah, USA
    J Clin Microbiol 51:2662-9. 2013
    ..Moreover, the geographic distribution of non-B variants is widespread. Data from HIV-1 drug resistance testing have the potential to significantly enhance the surveillance of HIV-1 variants in the United States. ..
  2. doi request reprint Evaluation of the Roche COBAS AmpliPrep/COBAS TaqMan HCV Test
    Michael T Pyne
    ARUP Institute for Clinical and Experimental Pathology, Salt Lake City, UT 84108, USA
    Diagn Microbiol Infect Dis 77:25-30. 2013
    ..Overall, the automated CAP/CTM assay exhibits excellent sensitivity, reproducibility, and dynamic range. Its performance is compatible with its use in guiding therapy using direct acting antivirals such as boceprevir and telaprevir. ..
  3. pmc Comparison of three Roche hepatitis B virus viral load assay formats
    Michael T Pyne
    ARUP Institute for Clinical and Experimental Pathology, Salt Lake City, Utah, USA
    J Clin Microbiol 50:2337-42. 2012
    ..6 log IU/ml. The incidence of false-positive negative controls in HP and CAP/CTM clinical testing was <0.5% over 6 to 7 months of testing...
  4. doi request reprint Large-scale comparison of Roche Cobas AmpliPrep/Cobas TaqMan and Abbott RealTime HIV assays
    Michael T Pyne
    ARUP Institute for Clinical and Experimental Pathology, 500 Chipeta Way, Salt Lake City, UT 84108, United States
    J Virol Methods 184:106-8. 2012
    ..9logcopies/mL. These data indicate that both tests may be susceptible to underquantitation, but the incidence is low in this large cohort of samples from across the United States...
  5. pmc Evaluation of the Abbott investigational use only realtime HIV-1 assay and comparison to the Roche Amplicor HIV-1 monitor test, version 1.5
    Michael T Pyne
    ARUP Institute for Clinical and Experimental Pathology, Salt Lake City, UT 84108, USA
    J Mol Diagn 11:347-54. 2009
    ..The automated RealTime assay exhibits excellent sensitivity, dynamic range, reproducibility, and group/subtype detection, albeit with consistently lower values than Amplicor...
  6. pmc Evaluation of the Abbott investigational use only RealTime hepatitis C virus (HCV) assay and comparison to the Roche TaqMan HCV analyte-specific reagent assay
    Michael T Pyne
    ARUP Institute for Clinical and Experimental Pathology, 500 Chipeta Way, Salt Lake City, UT 84108, USA
    J Clin Microbiol 47:2872-8. 2009
    ..In conclusion, the RealTime assay accurately measured HCV viral loads over a broad dynamic range, with no significant genotype bias...
  7. pmc Evaluation of the Roche Cobas AmpliPrep/Cobas TaqMan HIV-1 test and identification of rare polymorphisms potentially affecting assay performance
    Michael T Pyne
    ARUP Institute for Clinical and Experimental Pathology, 500 Chipeta Way, Salt Lake City, UT 84108, USA
    J Clin Microbiol 48:2852-8. 2010
    ..Otherwise, the CAP/CTM assay exhibits excellent sensitivity, dynamic range, reproducibility, and correlation with Amplicor in an automated format...