Allen A Thomas

Summary

Affiliation: Array BioPharma
Country: USA

Publications

  1. doi request reprint Non-charged thiamine analogs as inhibitors of enzyme transketolase
    Allen A Thomas
    Array BioPharma Inc, 3200 Walnut Street, Boulder, CO 80301, USA
    Bioorg Med Chem Lett 18:509-12. 2008
  2. doi request reprint Synthesis, in vitro and in vivo activity of thiamine antagonist transketolase inhibitors
    Allen A Thomas
    Array BioPharma Inc, 3200 Walnut Street, Boulder, CO 80301, USA
    Bioorg Med Chem Lett 18:2206-10. 2008
  3. ncbi request reprint Prodrug thiamine analogs as inhibitors of the enzyme transketolase
    Yvan Le Huerou
    Array BioPharma Inc, 3200 Walnut Street, Boulder, CO 80301, USA
    Bioorg Med Chem Lett 18:505-8. 2008

Collaborators

  • Yvan Le Huerou
  • S Kirk Wright
  • Christine Lemieux
  • Walter DeWolf
  • Todd T Romoff
  • Jed Pheneger
  • Steven S Gonzales
  • Gregory Poch
  • Steven A Boyd
  • Laura Hayter
  • Indrani Gunawardana
  • Patrice Lee
  • Jie Lin
  • Tomas Kaplan
  • Francis Sullivan
  • Solly Weiler
  • May Han
  • Jason de Meese

Detail Information

Publications3

  1. doi request reprint Non-charged thiamine analogs as inhibitors of enzyme transketolase
    Allen A Thomas
    Array BioPharma Inc, 3200 Walnut Street, Boulder, CO 80301, USA
    Bioorg Med Chem Lett 18:509-12. 2008
    ..The synthesis, SAR, and structure-based rationale for highly potent non-thiazolium TK antagonists are presented...
  2. doi request reprint Synthesis, in vitro and in vivo activity of thiamine antagonist transketolase inhibitors
    Allen A Thomas
    Array BioPharma Inc, 3200 Walnut Street, Boulder, CO 80301, USA
    Bioorg Med Chem Lett 18:2206-10. 2008
    ..Synthesis and SAR of transketolase inhibitors is described...
  3. ncbi request reprint Prodrug thiamine analogs as inhibitors of the enzyme transketolase
    Yvan Le Huerou
    Array BioPharma Inc, 3200 Walnut Street, Boulder, CO 80301, USA
    Bioorg Med Chem Lett 18:505-8. 2008
    ..The synthesis of such prodrugs and their evaluation in rodent models is reported...