Research Topics
| J K TaubenbergerSummaryAffiliation: Armed Forces Institute of Pathology Country: USA Publications
| Collaborators
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Detail Information
Publications
Initial genetic characterization of the 1918 "Spanish" influenza virusJ K Taubenberger
Division of Molecular Pathology, Department of Cellular Pathology, Armed Forces Institute of Pathology, Washington DC 20306 6000, USA
Science 275:1793-6. 1997..The sequences are consistent with a novel H1N1 influenza A virus that belongs to the subgroup of strains that infect humans and swine, not the avian subgroup...- Postmortem diagnosis of morbillivirus infection in bottlenose dolphins (Tursiops truncatus) in the Atlantic and Gulf of Mexico epizootics by polymerase chain reaction-based assayA Krafft
Department of Cellular Pathology, Armed Forces Institute of Pathology, Washington, D C 20306, USA
J Wildl Dis 31:410-5. 1995..Application of this method to autolyzed post-mortem tissues allows diagnoses of morbillivirus infection to be made in specimens which cannot be evaluated by histologic and immunocytochemical techniques... - Morbilliviral epizootic in bottlenose dolphins of the Gulf of MexicoT P Lipscomb
Armed Forces Institute of Pathology, Department of Veterinary Pathology, Washington, DC 20306, USA
J Vet Diagn Invest 8:283-90. 1996..Concomitant pulmonary aspergillosis was diagnosed histologically in 4 dolphins. This is the 5th reported morbilliviral epizootic of aquatic mammals and the 2nd involving bottlenose dolphins in the United States... - Histologic, immunohistochemical, and polymerase chain reaction studies of bottlenose dolphins from the 1987-1988 United States Atlantic coast epizooticF Y Schulman
Department of Veterinary Pathology, Armed Forces Institute of Pathology, Washington, DC 20306 6000, USA
Vet Pathol 34:288-95. 1997..Histologic, immunohistochemical, and PCR results provide strong evidence that morbillivirus infection was the primary cause of the 1987-1988 bottlenose dolphin epizootic... - The 1918 Spanish influenza: integrating history and biologyA H Reid
Division of Molecular Pathology, Department of Cellular Pathology, Armed Forces Institute of Pathology, 14th Street and Alaska Avenue N W, DC 20306 6000, USA
Microbes Infect 3:81-7. 2001..In 1918 an influenza pandemic killed 40 million people. It is now possible to study the genetic features of the 1918 virus. Such analyses will try to answer questions about the origin and the unusual virulence of this pandemic virus... 
Integrating historical, clinical and molecular genetic data in order to explain the origin and virulence of the 1918 Spanish influenza virusJ K Taubenberger
Department of Cellular Pathology and Genetics, Armed Forces Institute of Pathology, Room 1057D, Building 101, 1413 Research Boulevard, Rockville, MD 20850 3125, USA
Philos Trans R Soc Lond B Biol Sci 356:1829-39. 2001..This information should help to elucidate how pandemic influenza strains emerge and what genetic features contribute to their virulence...- Common metastatic carcinoma of California sea lions (Zalophus californianus): evidence of genital origin and association with novel gammaherpesvirusT P Lipscomb
Department of Veterinary Pathology, Armed Forces Institute of Pathology, Washington, DC 20306 6000, USA
Vet Pathol 37:609-17. 2000..These findings support the genital origin of the sea lion carcinoma and implicate a novel gammaherpesvirus as a possible cause... - Characterization of the 1918 "Spanish" influenza virus neuraminidase geneA H Reid
Division of Molecular Pathology, Department of Cellular Pathology, Armed Forces Institute of Pathology, Washington, DC 20306 6000, USA
Proc Natl Acad Sci U S A 97:6785-90. 2000..Phylogenetically, the 1918 neuraminidase gene appears to be intermediate between mammals and birds, suggesting that it was introduced into mammals just before the 1918 pandemic... - Influenza A virus neuraminidase: regions of the protein potentially involved in virus-host interactionsT G Fanning
Division of Molecular Pathology, Armed Forces Institute of Pathology, Washington, DC, 20306 6000, USA
Virology 276:417-23. 2000..Many PIRs are coincident with antigenic or glycosylation sites. Other PIRs may represent additional antigenic sites or may be involved in other aspects of virus-host biology... - Influenza RNA not detected in archival brain tissues from acute encephalitis lethargica cases or in postencephalitic Parkinson casesS McCall
FDepartment of Cellular Pathology and Genetics, Armed Forces Institute of Pathology, Washington, DC, USA
J Neuropathol Exp Neurol 60:696-704. 2001..Thus, it is unlikely that the 1918 influenza virus was neurotropic and directly responsible for the outbreak of EL... - Origin and evolution of the 1918 "Spanish" influenza virus hemagglutinin geneA H Reid
Division of Molecular Pathology, Department of Cellular Pathology, Armed Forces Institute of Pathology, Washington, DC 20306 6000, USA
Proc Natl Acad Sci U S A 96:1651-6. 1999..Phylogenetic analyses suggest that the 1918 virus HA gene, although more closely related to avian strains than any other mammalian sequence, is mammalian and may have been adapting in humans before 1918... - Evaluation of PCR testing of ethanol-fixed nasal swab specimens as an augmented surveillance strategy for influenza virus and adenovirus identificationA E Krafft
Department of Molecular Pathology, Armed Forces Institute of Pathology, 1413 Research Blvd, Rockville, MD 20850 3125, USA
J Clin Microbiol 43:1768-75. 2005..Lower specificities of the real-time assays corresponded to the increased detection of PCR-positive but culture-negative specimens. Influenza virus RNA was detected as well or better after 6 months of storage in ethanol... - Relationship of pre-1918 avian influenza HA and NP sequences to subsequent avian influenza strainsA H Reid
Division of Molecular Pathology, Department of Cellular Pathology and Genetics, Armed Forces Institute of Pathology, 1413 Research Boulevard, Building 101, Room 1057D, Rockville, MD 20850-3125, USA
Avian Dis 47:921-5. 2003..The 1917 avian NP sequences are also closely related to modern avian sequences and distinct from the mammalian clade in which the 1918 NP sequence is found... - Experimenting on the past: the enigma of von Economo's encephalitis lethargicaA H Reid
Department of Cellular Pathology and Genetics, Armed Forces Institute of Pathology, Washington, DC, USA
J Neuropathol Exp Neurol 60:663-70. 2001..Similarly, tissue samples from EL victims can now be examined for evidence of infection by the 1918 influenza virus... - Morbilliviral dermatitis in sealsT P Lipscomb
Department of Veterinary Pathology, Armed Forces Institute of Pathology, Washington, DC 20306 6000, USA
Vet Pathol 38:724-6. 2001..This is the first report of morbilliviral dermatitis in marine mammals... - Molecular genetic evidence of a novel morbillivirus in a long-finned pilot whale (Globicephalus melas)J K Taubenberger
Armed Forces Institute of Pathology, Washington, D C, USA
Emerg Infect Dis 6:42-5. 2000..Novel sequences most closely related to, but distinct from, those of dolphin and porpoise morbilliviruses suggest that this virus may represent a third member of the cetacean morbillivirus group... - Quantitative real-time reverse transcription-PCR assay for cyclin D1 expression: utility in the diagnosis of mantle cell lymphomaK E Bijwaard
Department of Cellular Pathology, Armed Forces Institute of Pathology, 6825 16th St NW, Washington, DC 20306 6000, USA
Clin Chem 47:195-201. 2001..Quantification of cyclin D1 expression can distinguish MCL from other lymphomas... - Genetic heterogeneity in ductal carcinoma of the breastJ H Lichy
Department of Cellular Pathology, Armed Forces Institute of Pathology, Washington, DC 20306 6000, USA
Lab Invest 80:291-301. 2000..The results indicate that the different tumor components observed microscopically in breast cancer specimens often represent genetically divergent clones... - Diagnosis of influenza virus: coming to grips with the molecular eraJ K Taubenberger
Department of Cellular Pathology and Genetics, Division of Molecular Pathology, Armed Forces Institute of Pathology, Rockville, MD 20850 3125, USA
Mol Diagn 6:291-305. 2001..RT-PCR for influenza also can be performed from tissue biopsy specimens for both retrospective diagnosis and research... - Using RRT-PCR analysis and virus isolation to determine the prevalence of avian influenza virus infections in ducks at Minto Flats State Game Refuge, Alaska, during August 2005J A Runstadler
Institute of Arctic Biology, University of Alaska Fairbanks, Fairbanks, AK 99775, USA
Arch Virol 152:1901-10. 2007..Our success during 2005 indicates Minto Flats will be a valuable study site for a longitudinal research project designed to gain further insight into the natural history, evolution, and ecology of AIV in wild birds... - Allelic loss on chromosome band 18p11.3 occurs early and reveals heterogeneity in breast cancer progressionK Kittiniyom
Department of Pathology, Virginia Commonweath University, Richmond, USA
Breast Cancer Res 3:192-8. 2001..These analyses suggest chromosome 18p11 alteration is a common and early event in breast disease... - Sequence of the 1918 pandemic influenza virus nonstructural gene (NS) segment and characterization of recombinant viruses bearing the 1918 NS genesC F Basler
Department of Microbiology, Mount Sinai School of Medicine, New York, NY 10029, USA
Proc Natl Acad Sci U S A 98:2746-51. 2001..This attenuation in mice may be related to the human origin of the 1918 NS1 gene. These results suggest that interaction of the NS1 protein with host-cell factors plays a significant role in viral pathogenesis...