Research Topics
| Ann H ReidSummaryAffiliation: Armed Forces Institute of Pathology Country: USA Publications
| Collaborators
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Detail Information
Publications
Origin and evolution of the 1918 "Spanish" influenza virus hemagglutinin geneA H Reid
Division of Molecular Pathology, Department of Cellular Pathology, Armed Forces Institute of Pathology, Washington, DC 20306 6000, USA
Proc Natl Acad Sci U S A 96:1651-6. 1999..Phylogenetic analyses suggest that the 1918 virus HA gene, although more closely related to avian strains than any other mammalian sequence, is mammalian and may have been adapting in humans before 1918...- Characterization of the 1918 "Spanish" influenza virus neuraminidase geneA H Reid
Division of Molecular Pathology, Department of Cellular Pathology, Armed Forces Institute of Pathology, Washington, DC 20306 6000, USA
Proc Natl Acad Sci U S A 97:6785-90. 2000..Phylogenetically, the 1918 neuraminidase gene appears to be intermediate between mammals and birds, suggesting that it was introduced into mammals just before the 1918 pandemic... 
The 1918 Spanish influenza: integrating history and biologyA H Reid
Division of Molecular Pathology, Department of Cellular Pathology, Armed Forces Institute of Pathology, 14th Street and Alaska Avenue N W, DC 20306 6000, USA
Microbes Infect 3:81-7. 2001..In 1918 an influenza pandemic killed 40 million people. It is now possible to study the genetic features of the 1918 virus. Such analyses will try to answer questions about the origin and the unusual virulence of this pandemic virus...- Characterization of the 1918 "Spanish" influenza virus matrix gene segmentAnn H Reid
Division of Molecular Pathology, Department of Cellular Pathology and Genetics, Armed Forces Institute of Pathology, Rockville, Maryland 20850 3125, USA
J Virol 76:10717-23. 2002.... - Characterization of the 1918 influenza virus polymerase genesJeffery K Taubenberger
Department of Molecular Pathology, Armed Forces Institute of Pathology, Rockville, Maryland 20850, USA
Nature 437:889-93. 2005..The sequence changes identified here may be important in the adaptation of influenza viruses to humans... - Capturing a killer flu virusJeffery K Taubenberger
Armed Forces Institute of Pathology, Rockville, MD, USA
Sci Am 292:48-57. 2005 - Evidence of an absence: the genetic origins of the 1918 pandemic influenza virusAnn H Reid
Armed Forces Institute of Pathology, Department of Molecular Pathology, 1413 Research Boulevard, Building 101, Rockville, Maryland 20850, USA
Nat Rev Microbiol 2:909-14. 2004..Determining whether a pandemic influenza virus can emerge by different mechanisms will affect the scope and focus of surveillance and prevention efforts... - 1917 avian influenza virus sequences suggest that the 1918 pandemic virus did not acquire its hemagglutinin directly from birdsThomas G Fanning
Division of Molecular Pathology, Department of Cellular Pathology and Genetics, Armed Forces Institute of Pathology, Rockville, Maryland 20850 3125, USA
J Virol 76:7860-2. 2002.... - Novel origin of the 1918 pandemic influenza virus nucleoprotein geneAnn H Reid
Armed Forces Institute of Pathology, Department of Molecular Pathology, 1413 Research Blvd, Building 101, Rockville, MD 20850-3125, USA
J Virol 78:12462-70. 2004.... - 1918 influenza pandemic caused by highly conserved viruses with two receptor-binding variantsAnn H Reid
Department of Cellular Pathology and Genetics, Armed Forces Institute of Pathology, 1413 Research Boulevard, Building 101, Rockville, MD 20850-3125, USA
Emerg Infect Dis 9:1249-53. 2003 - The origin of the 1918 pandemic influenza virus: a continuing enigmaAnn H Reid
Division of Molecular Pathology, Department of Cellular Pathology and Genetics, Armed Forces Institute of Pathology, 1413 Research Blvd, Building 101, Room 1057, Rockville, MD 20850-3125, USA
J Gen Virol 84:2285-92. 2003..Determining whether pandemic influenza virus strains can emerge via different pathways will affect the scope and focus of surveillance and prevention efforts... - Evaluation of PCR testing of ethanol-fixed nasal swab specimens as an augmented surveillance strategy for influenza virus and adenovirus identificationA E Krafft
Department of Molecular Pathology, Armed Forces Institute of Pathology, 1413 Research Blvd, Rockville, MD 20850 3125, USA
J Clin Microbiol 43:1768-75. 2005..Lower specificities of the real-time assays corresponded to the increased detection of PCR-positive but culture-negative specimens. Influenza virus RNA was detected as well or better after 6 months of storage in ethanol... - Initial genetic characterization of the 1918 "Spanish" influenza virusJ K Taubenberger
Division of Molecular Pathology, Department of Cellular Pathology, Armed Forces Institute of Pathology, Washington DC 20306 6000, USA
Science 275:1793-6. 1997..The sequences are consistent with a novel H1N1 influenza A virus that belongs to the subgroup of strains that infect humans and swine, not the avian subgroup... - Integrating historical, clinical and molecular genetic data in order to explain the origin and virulence of the 1918 Spanish influenza virusJ K Taubenberger
Department of Cellular Pathology and Genetics, Armed Forces Institute of Pathology, Room 1057D, Building 101, 1413 Research Boulevard, Rockville, MD 20850 3125, USA
Philos Trans R Soc Lond B Biol Sci 356:1829-39. 2001..This information should help to elucidate how pandemic influenza strains emerge and what genetic features contribute to their virulence... - Influenza A virus neuraminidase: regions of the protein potentially involved in virus-host interactionsT G Fanning
Division of Molecular Pathology, Armed Forces Institute of Pathology, Washington, DC, 20306 6000, USA
Virology 276:417-23. 2000..Many PIRs are coincident with antigenic or glycosylation sites. Other PIRs may represent additional antigenic sites or may be involved in other aspects of virus-host biology... - Lung pathology of severe acute respiratory syndrome (SARS): a study of 8 autopsy cases from SingaporeTeri J Franks
Department of Pulmonary and Mediastinal Pathology, Armed Forces Institute of Pathology, Wshington, DC 20306, USA
Hum Pathol 34:743-8. 2003..Understanding the pathology of DAD in SARS patients may provide the basis for therapeutic strategies. Further studies of the pathogenesis of SARS may reveal new insight into the mechanisms of DAD... - Relationship of pre-1918 avian influenza HA and NP sequences to subsequent avian influenza strainsA H Reid
Division of Molecular Pathology, Department of Cellular Pathology and Genetics, Armed Forces Institute of Pathology, 1413 Research Boulevard, Building 101, Room 1057D, Rockville, MD 20850-3125, USA
Avian Dis 47:921-5. 2003..The 1917 avian NP sequences are also closely related to modern avian sequences and distinct from the mammalian clade in which the 1918 NP sequence is found... - Metagenomics: a call for bringing a new science into the classroom (while it's still new)Anne Jurkowski
Division on Earth and Life Studies, Center for Education, National Research Council, Washington, DC 20001, USA
CBE Life Sci Educ 6:260-5. 2007 - Experimenting on the past: the enigma of von Economo's encephalitis lethargicaA H Reid
Department of Cellular Pathology and Genetics, Armed Forces Institute of Pathology, Washington, DC, USA
J Neuropathol Exp Neurol 60:663-70. 2001..Similarly, tissue samples from EL victims can now be examined for evidence of infection by the 1918 influenza virus... - Influenza RNA not detected in archival brain tissues from acute encephalitis lethargica cases or in postencephalitic Parkinson casesS McCall
FDepartment of Cellular Pathology and Genetics, Armed Forces Institute of Pathology, Washington, DC, USA
J Neuropathol Exp Neurol 60:696-704. 2001..Thus, it is unlikely that the 1918 influenza virus was neurotropic and directly responsible for the outbreak of EL...