John C H Spence

Summary

Affiliation: Arizona State University
Country: USA

Publications

  1. ncbi request reprint Diffraction and imaging from a beam of laser-aligned proteins: resolution limits
    J C H Spence
    Department of Physics and Astronomy, Arizona State University, Tempe, AZ 85287 1504, USA
    Acta Crystallogr A 61:237-45. 2005
  2. doi request reprint Lawrence Bragg, microdiffraction and X-ray lasers
    J C H Spence
    Department of Physics, Arizona State University, Tempe, 85282, USA
    Acta Crystallogr A 69:25-33. 2013
  3. doi request reprint X-ray lasers for structural and dynamic biology
    J C H Spence
    Department of Physics, Arizona State University, Tempe, AZ 85287, USA
    Rep Prog Phys 75:102601. 2012
  4. doi request reprint Phasing of coherent femtosecond X-ray diffraction from size-varying nanocrystals
    John C H Spence
    Department of Physics, Arizona State University, Tempe, AZ 85287, USA
    Opt Express 19:2866-73. 2011
  5. ncbi request reprint Coherence and sampling requirements for diffractive imaging
    J C H Spence
    Department of Physics and Astronomy, Arizona State University, Tempe, AZ 85287 1505, USA
    Ultramicroscopy 101:149-52. 2004
  6. ncbi request reprint Convergent-beam low energy electron diffraction (CBLEED) and the measurement of surface dipole layers
    J C H Spence
    Department of Physics and Astronomy, College of Liberal Arts and Science, Arizona State University, Tempe, AZ 85287 1504, USA
    Microsc Microanal 10:128-33. 2004
  7. ncbi request reprint Three-dimensional diffractive imaging for crystalline monolayers with one-dimensional compact support
    J C H Spence
    Department of Physics, Arizona State University, Tempe, AZ 85287 1504, USA
    J Struct Biol 144:209-18. 2003
  8. doi request reprint Femtosecond protein nanocrystallography-data analysis methods
    Richard A Kirian
    Department of Physics, Arizona State University, Tempe, Arizona 85287 USA
    Opt Express 18:5713-23. 2010
  9. ncbi request reprint Signal, noise, and resolution in correlated fluctuations from snapshot small-angle x-ray scattering
    Richard A Kirian
    Department of Physics, Arizona State University, Tempe, Arizona 85287, USA
    Phys Rev E Stat Nonlin Soft Matter Phys 84:011921. 2011
  10. doi request reprint Three-dimensional single-particle imaging using angular correlations from X-ray laser data
    Haiguang Liu
    Department of Physics, Arizona State University, Tempe, AZ 85287, USA
    Acta Crystallogr A 69:365-73. 2013

Collaborators

Detail Information

Publications28

  1. ncbi request reprint Diffraction and imaging from a beam of laser-aligned proteins: resolution limits
    J C H Spence
    Department of Physics and Astronomy, Arizona State University, Tempe, AZ 85287 1504, USA
    Acta Crystallogr A 61:237-45. 2005
    ..For a typical virus (TMV), a 50 W continuous-wave laser is adequate for subnanometre resolution at room temperature. The dependence of resolution on laser power, temperature, molecular size, shape and dielectric constant is analyzed...
  2. doi request reprint Lawrence Bragg, microdiffraction and X-ray lasers
    J C H Spence
    Department of Physics, Arizona State University, Tempe, 85282, USA
    Acta Crystallogr A 69:25-33. 2013
    ..In this way, using short pulses instead of freezing, the nexus between dose, resolution and crystal size has been broken, opening the way to time-resolved diffraction without damage for a stream of identical particles...
  3. doi request reprint X-ray lasers for structural and dynamic biology
    J C H Spence
    Department of Physics, Arizona State University, Tempe, AZ 85287, USA
    Rep Prog Phys 75:102601. 2012
    ..Possibilities for time-resolved chemistry using fast WAXS (solution scattering) from mixtures is reviewed, toward the general goal of making molecular movies of biochemical processes...
  4. doi request reprint Phasing of coherent femtosecond X-ray diffraction from size-varying nanocrystals
    John C H Spence
    Department of Physics, Arizona State University, Tempe, AZ 85287, USA
    Opt Express 19:2866-73. 2011
    ..By using information on the particle-size distribution within the patterns, this digital method succeeds, using all the data, without knowledge of the distribution of particle size or requiring atomic-resolution data...
  5. ncbi request reprint Coherence and sampling requirements for diffractive imaging
    J C H Spence
    Department of Physics and Astronomy, Arizona State University, Tempe, AZ 85287 1505, USA
    Ultramicroscopy 101:149-52. 2004
    ..The results are relevant to the design of diffraction cameras for CDI and plans for femotosecond X-ray diffraction from individual proteins...
  6. ncbi request reprint Convergent-beam low energy electron diffraction (CBLEED) and the measurement of surface dipole layers
    J C H Spence
    Department of Physics and Astronomy, College of Liberal Arts and Science, Arizona State University, Tempe, AZ 85287 1504, USA
    Microsc Microanal 10:128-33. 2004
    ..We briefly discuss also the application of this method to oxides and the formation of atomic-resolution scanning images in an idealized instrument in which coherent diffracted LEED orders overlap...
  7. ncbi request reprint Three-dimensional diffractive imaging for crystalline monolayers with one-dimensional compact support
    J C H Spence
    Department of Physics, Arizona State University, Tempe, AZ 85287 1504, USA
    J Struct Biol 144:209-18. 2003
    ..The method should greatly reduce the time and labor needed for data acquisition and analysis in cryo-electron microscopy of organic thin crystals by avoiding the need to record images at high tilt angles...
  8. doi request reprint Femtosecond protein nanocrystallography-data analysis methods
    Richard A Kirian
    Department of Physics, Arizona State University, Tempe, Arizona 85287 USA
    Opt Express 18:5713-23. 2010
    ..We determine the number of shots needed for a required accuracy in structure factor measurement and resolution, and investigate the convergence of our Monte-Carlo integration method...
  9. ncbi request reprint Signal, noise, and resolution in correlated fluctuations from snapshot small-angle x-ray scattering
    Richard A Kirian
    Department of Physics, Arizona State University, Tempe, Arizona 85287, USA
    Phys Rev E Stat Nonlin Soft Matter Phys 84:011921. 2011
    ....
  10. doi request reprint Three-dimensional single-particle imaging using angular correlations from X-ray laser data
    Haiguang Liu
    Department of Physics, Arizona State University, Tempe, AZ 85287, USA
    Acta Crystallogr A 69:365-73. 2013
    ..The method is validated with theoretical data calculated from several representative molecules and applied to the reconstruction of nanoparticles from experimental data collected at the Linac Coherent Light Source...
  11. ncbi request reprint Diffractive electron imaging of nanoparticles on a substrate
    Jinsong Wu
    Department of Physics and Astronomy, Arizona State University, Tempe, Arizona 85287 1504, USA
    Nat Mater 4:912-6. 2005
    ..The method has the advantage that the reconstructed exit-face wavefunction is free of the aberrations of the objective lens normally used in the microscope, whereas resolution is limited only by thermal vibration and noise...
  12. pmc Structure-factor analysis of femtosecond microdiffraction patterns from protein nanocrystals
    Richard A Kirian
    Department of Physics, Arizona State University, Tempe, Arizona 85287, USA
    Acta Crystallogr A 67:131-40. 2011
    ..The implications for improving the efficiency of data collection by allowing the use of very small crystals, for radiation-damage reduction and for time-resolved diffraction studies at room temperature are discussed...
  13. ncbi request reprint Damped and thermal motion of laser-aligned hydrated macromolecule beams for diffraction
    D Starodub
    Department of Physics and Astronomy, Arizona State University, P O Box 871504 Tempe, Arizona 85287 1504, USA
    J Chem Phys 123:244304. 2005
    ....
  14. ncbi request reprint Dose, exposure time and resolution in serial X-ray crystallography
    D Starodub
    Department of Physics, Arizona State University, PO Box 871504, Tempe, AZ 85287 1504, USA
    J Synchrotron Radiat 15:62-73. 2008
    ....
  15. pmc Femtosecond nanocrystallography using X-ray lasers for membrane protein structure determination
    Petra Fromme
    Department of Chemistry and Biochemistry, Arizona State University, Tempe, AZ 85287 1604, USA
    Curr Opin Struct Biol 21:509-16. 2011
    ..We briefly review the possibilities for time-resolved crystallography, and the potential for making 'molecular movies' of membrane proteins at work...
  16. ncbi request reprint Ordering energies and occupancies in doped TiAl, and dedicated ALCHEMI instrumentation
    J C H Spence
    Department of Physics and Astronomy, Arizona State University, Tempe, AZ, 85287 1504, USA
    Microsc Microanal 8:241-6. 2002
    ..The resulting occupancy information can provide essential input parameters for atomistic alloy design algorithms, and can provide entirely new information on interstitial occupancies in minerals, ceramics, semiconductors, and alloys...
  17. doi request reprint In situ EELS study of dehydration of Al(OH)₃ by electron beam irradiation
    Nan Jiang
    Department of Physics, Arizona State University, Tempe, AZ 85287 1504, USA
    Ultramicroscopy 111:860-4. 2011
    ..The time-dependent O K-edge shows that the pre-edge peak in the O K-edge of Al(OH)₃ is induced by the formation of unpaired O, rather than an intrinsic feature of the OH bond...
  18. ncbi request reprint Phase recovery and lensless imaging by iterative methods in optical, X-ray and electron diffraction
    J C H Spence
    Department of Physics and Astronomy, Arizona State University, Tempe, AZ 85287 1504, USA
    Philos Transact A Math Phys Eng Sci 360:875-95. 2002
    ..These new interactions can be expected to provide new information, perhaps, for example, in biology, with the advantage of less damage to samples...
  19. ncbi request reprint Kinematic and dynamical CBED for solving thin organic films at low temperature; experimental tests with anthracene
    J S Wu
    Department of Physics and Astronomy, Arizona State University, Tempe, AZ 85287 1504, USA
    Acta Crystallogr A 58:580-9. 2002
    ..The faint peaks due to H-atom positions may be distinguished. Key issues influencing the validity of the method such as the appropriate dimension of the structure-factor matrix, sample thickness and crystal orientation are discussed...
  20. doi request reprint Valence electron energy-loss spectroscopy study of ZrSiO₄ and ZrO₂
    Nan Jiang
    Department of Physics, Arizona State University, AZ 85287 1504, USA Electronic address
    Ultramicroscopy 134:68-76. 2013
    ..Although similarities in the VEELS exist between ZrSiO4 and m-ZrO2, two major differences are also noticed and explained in terms of composition and structure differences...
  21. ncbi request reprint On the dose-rate threshold of beam damage in TEM
    Nan Jiang
    Department of Physics, Arizona State University, Tempe AZ 85287 1504, USA
    Ultramicroscopy 113:77-82. 2012
    ..The accumulation of damage can only occur when the damage rate is higher than the recovery rate. For surface sputtering process in TEM, the recovery rate is negligible. Therefore, there is no threshold dose rate for surface sputtering...
  22. ncbi request reprint On the measurement of thickness in nanoporous materials by EELS
    Nan Jiang
    Department of Physics, Arizona State University, Tempe, AZ 85287 1504, USA
    Ultramicroscopy 111:62-5. 2010
    ..In homogeneous nanoporous systems, on the other hand, the log-ratio method is still valid, but the inelastic scattering mean-free-path is no longer equal to that in the same bulk system...
  23. ncbi request reprint Observation of long-range compositional fluctuations in glasses: implications for atomic and electronic structure
    Nan Jiang
    Department of Physics and Astronomy, Arizona State University, Tempe, AZ 85287 1504, USA
    Micron 39:698-702. 2008
    ..Comparisons with spectra from compositionally equivalent crystals, and multiple-scattering calculations which include core-hole effects are used to analyze the data...
  24. ncbi request reprint Phasing diffraction data from a stream of hydrated proteins
    Jin Song Wu
    Department of Physics and Astronomy, Arizona State University, Tempe, Arizona 85287 1504, USA
    J Opt Soc Am A Opt Image Sci Vis 22:1453-9. 2005
    ..Rev. Lett. 92, 198102 (2004)]. We consider also the effect of empty ice balls on the patterns. The algorithm can also be used to align images with different randomly chosen origins, so that the same embedded subunits overlap...
  25. ncbi request reprint SEM imaging of liquid jets
    Daniel P DePonte
    Department of Physics, Arizona State University, Tempe, AZ 85287, United States
    Micron 40:507-9. 2009
    ..ESEM imaging of liquid jets offers a valuable research tool for the study of aerosol production, combustion processes, ink-jet generation, and many other attributes of micro- and nanojet systems...
  26. doi request reprint Reconstruction from a single diffraction pattern of azimuthally projected electron density of molecules aligned parallel to a single axis
    D K Saldin
    Department of Physics, University of Wisconsin Milwaukee, PO Box 413, Milwaukee, WI 53201, USA
    Acta Crystallogr A 66:32-7. 2010
    ....
  27. ncbi request reprint Single molecule diffraction
    J C H Spence
    Department of Physics and Astronomy, Arizona State University, Tempe, Arizona 85287 1504, USA
    Phys Rev Lett 92:198102. 2004
    ..Iterative methods for solving the phase problem are indicated. Comparisons with a related plan for pulsed x-ray diffraction from single proteins in a molecular beam are provided...
  28. ncbi request reprint Three-dimensional coherent x-ray diffraction imaging of a ceramic nanofoam: determination of structural deformation mechanisms
    A Barty
    Lawrence Livermore National Laboratory, 7000 East Avenue, Livermore, CA 94550, USA
    Phys Rev Lett 101:055501. 2008
    ....