Research Topics
| Yuseob KimSummaryAffiliation: Arizona State University Country: USA Publications
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Detail Information
Publications
Allele frequency distribution under recurrent selective sweepsYuseob Kim
Department of Biology, University of Rochester, Rochester, New York 14620, USA
Genetics 172:1967-78. 2006..It is shown that, using this approximation and multilocus polymorphism data, genomewide parameters of directional selection can be estimated...
The enrichment of TATA box and the scarcity of depleted proximal nucleosome in the promoters of duplicated yeast genesYuseob Kim
School of Life Sciences, Arizona State University, Tempe, AZ 85287, USA
J Mol Evol 70:69-73. 2010..This suggests that variably expressed genes, due to the functional organization in their promoters, have higher duplicability than constitutively expressed genes...- Signatures of recent directional selection under different models of population expansion during colonization of new selective environmentsYuseob Kim
Center of Rapid Evolution CORE, Department of Zoology, University of Wisconsin, Madison, Wisconsin 53705, USA
Genetics 184:571-85. 2010..This result demonstrates the importance of correctly modeling the ecological process in inferring adaptive evolution using DNA sequence polymorphism... 
Rate of adaptive peak shifts with partial genetic robustnessYuseob Kim
The School of Life Sciences and the Center for Evolutionary Functional Genomics, The Biodesign Institute, Arizona State University, PO Box 875301, Tempe, Arizona 85287 5301, USA
Evolution 61:1847-56. 2007..It is shown that peak shifts can be delayed or accelerated depending on the conditions of genetic robustness. The evolutionary significance of these processes is discussed...- Approximations for the hitchhiking effect caused by the evolution of antimalarial-drug resistanceKristan A Schneider
School of Life Sciences, Arizona State University, 1711 South Rural Road, Tempe, AZ 85287, USA
J Math Biol 62:789-832. 2011..Reversely, for a given reduction of heterozygosity, it is possible to identify the corresponding parameters. Moreover, we will show that incorporating host heterogeneity leads to an increased hitchhiking effect... - The dynamics of mutations associated with anti-malarial drug resistance in Plasmodium falciparumAnanias A Escalante
School of Life Sciences, Arizona State University, PO Box 874501, Tempe, AZ 85287 4501, USA
Trends Parasitol 25:557-63. 2009..falciparum requires approaches that consider the parasite population structure among other demographic processes... - Purifying selection modulates the estimates of population differentiation and confounds genome-wide comparisons across single-nucleotide polymorphismsTakahiro Maruki
Center for Evolutionary Medicine and Informatics, The Biodesign Institute, Arizona State University
Mol Biol Evol 29:3617-23. 2012.... - Hitchhiking effect of a beneficial mutation spreading in a subdivided populationYuseob Kim
Center for Evolutionary Medicine and Informatics and School of Life Sciences, Arizona State University, Tempe, Arizona 85287, USA
Genetics 189:213-26. 2011..This raises a possibility of detecting a "hidden" geographic structure of population by carefully analyzing the pattern of a selective sweep... - Adaptation in sexuals vs. asexuals: clonal interference and the Fisher-Muller modelYuseob Kim
Department of Biology, University of Rochester, Rochester, New York 14627, USA
Genetics 171:1377-86. 2005..We find that some of these statistics are surprisingly similar between sexuals and asexuals. These results highlight the importance of the choice of substitution model in assessing the Fisher-Muller advantage of sex... - An analytical model for genetic hitchhiking in the evolution of antimalarial drug resistanceKristan A Schneider
School of Life Sciences, Arizona State University, 1711 South Rural Road Tempe, AZ 85287, USA
Theor Popul Biol 78:93-108. 2010..Finally, we show how to incorporate host heterogeneity, and generalize our results to this biologically more realistic case... - A pseudohitchhiking model of X vs. autosomal diversityAndrea J Betancourt
Department of Biology, University of Rochester, Rochester, New York 14627, USA
Genetics 168:2261-9. 2004..autosomal diversity is reduced by hitchhiking under a broad range of conditions, but when there is no recombination in males, as in Drosophila, the required conditions are considerably more restrictive... - Effect of strong directional selection on weakly selected mutations at linked sites: implication for synonymous codon usageYuseob Kim
Department of Biological Statistics and Computational Biology, Cornell University, New York, USA
Mol Biol Evol 21:286-94. 2004..It is shown that this observation can be reasonably well accounted for if a large fraction of the nonsynonymous substitutions on genes in the data set are driven by strong directional selection... - Pattern of polymorphism after strong artificial selection in a domestication eventHideki Innan
Human Genetics Center, School of Public Health, University of Texas Health Science Center, Houston, TX 77030, USA
Proc Natl Acad Sci U S A 101:10667-72. 2004..These theoretical results are discussed in light of data collected from maize. Although the main focus of this article is on domestication, this model can also be generalized to describe selective sweeps from standing genetic variation... - Linkage disequilibrium as a signature of selective sweepsYuseob Kim
Department of Biological Statistics and Computational Biology, Cornell University, Ithaca, New York 14853, USA
Genetics 167:1513-24. 2004..However, the improvement made by including LD is rather small, suggesting that most of the relevant information regarding selective sweeps is captured by the spatial distribution and marginal allele frequencies of polymorphisms... - Identification of a locus under complex positive selection in Drosophila simulans by haplotype mapping and composite-likelihood estimationColin D Meiklejohn
Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, Massachusetts 02138, USA
Genetics 168:265-79. 2004.... - Detecting local adaptation using the joint sampling of polymorphism data in the parental and derived populationsHideki Innan
Graduate University for Advanced Studies, Hayama, Kanagawa 240 0193, Japan
Genetics 179:1713-20. 2008..Therefore, for detecting the signature of local adaptation in polymorphism data, it is important to evaluate the data from both parental and derived populations simultaneously... - Distinguishing between selective sweeps and demography using DNA polymorphism dataJeffrey D Jensen
Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York 14853, USA
Genetics 170:1401-10. 2005.... - Genomic scans for selective sweeps using SNP dataRasmus Nielsen
Department of Biological Statistics and Computational Biology, Cornell University, Ithaca, New York 14853, USA
Genome Res 15:1566-75. 2005..Evidence for selective sweeps is also found in many other regions, including genes known to be associated with disease risk such as DPP10 and COL4A3... - Selective sweeps in the presence of interference among partially linked lociYuseob Kim
Department of Biological Statistics and Computational Biology, Cornell University, Ithaca, New York 14853, USA
Genetics 164:389-98. 2003..Analytical approximations are obtained for the case of complete linkage for which interference between competing beneficial alleles is maximal...