Research Topics
| Heather A Bimonte-NelsonSummaryAffiliation: Arizona State University Country: USA Publications
Research Grants
| Collaborators
|
Detail Information
Publications
Progesterone reverses the spatial memory enhancements initiated by tonic and cyclic oestrogen therapy in middle-aged ovariectomized female ratsHeather A Bimonte-Nelson
Department of Psychology, Arizona State University, PO Box 871104, Tempe, AZ 85287, USA
Eur J Neurosci 24:229-42. 2006..Further, there appears to be a dissociation between HT effects on cognition and mortality rates...
Patterns of neurotrophin protein levels in male and female Fischer 344 rats from adulthood to senescence: how young is "young" and how old is "old"?Heather A Bimonte-Nelson
Department of Psychology, Behavioral Neuroscience Division, Arizona State University, Tempe, Arizona 85287, USA
Exp Aging Res 34:13-26. 2008..The current findings suggest that profound changes in neurotrophin protein levels can occur within only a few months time, and that these changes influence whether age-related neurotrophin alterations are realized...- Neuroscientists as cartographers: mapping the crossroads of gonadal hormones, memory and age using animal modelsHeather A Bimonte-Nelson
Department of Psychology, Arizona State University, Tempe, AZ 85287, USA
Molecules 15:6050-105. 2010.... - Continuous estrone treatment impairs spatial memory and does not impact number of basal forebrain cholinergic neurons in the surgically menopausal middle-aged ratElizabeth B Engler-Chiurazzi
Department of Psychology, Arizona State University, Tempe, AZ 85287, USA
Horm Behav 62:1-9. 2012..Accumulating data suggest that E1 is not likely to be among these key beneficial estrogens... 
High serum androstenedione levels correlate with impaired memory in the surgically menopausal rat: a replication and new findingsBryan W Camp
Department of Psychology, Arizona State University, Tempe, AZ 85287, USA
Eur J Neurosci 36:3086-95. 2012..Furthermore, while spatial reference memory performance might be related to the GABAergic system, it does not appear to be altered with androstenedione administration, at least at the doses used in the current study...- Cognitive-impairing effects of medroxyprogesterone acetate in the rat: independent and interactive effects across timeB Blair Braden
Department of Psychology, Arizona State University, P O Box 871104, Tempe, AZ 85287, USA
Psychopharmacology (Berl) 218:405-18. 2011..Recent evidence in aged ovariectomized (Ovx) rodents shows that short-term MPA treatment impairs cognition and alters the GABAergic system... - Tonic Premarin dose-dependently enhances memory, affects neurotrophin protein levels and alters gene expression in middle-aged ratsElizabeth Engler-Chiurazzi
Department of Psychology, Arizona State University, Tempe, AZ 85287, USA
Neurobiol Aging 32:680-97. 2011..These findings indicate that Premarin can impact memory and the brain, and that dosing should be recognized as a clinically relevant factor possibly affecting the direction and efficacy of cognitive outcome... - Premarin improves memory, prevents scopolamine-induced amnesia and increases number of basal forebrain choline acetyltransferase positive cells in middle-aged surgically menopausal ratsJazmin I Acosta
Department of Psychology, Arizona State University, Tempe, AZ 85287, USA
Horm Behav 55:454-64. 2009..These findings are similar to those reported previously for 17 beta-estradiol, and suggest that CEE can provide cognitive benefits on spatial learning, reference and working memory, possibly through cholinergic mechanisms... - The cognitive effects of conjugated equine estrogens depend on whether menopause etiology is transitional or surgicalJazmin I Acosta
Department of Psychology, Arizona State University, Tempe, Arizona 85287, USA
Endocrinology 151:3795-804. 2010..That we now show surgical vs. transitional modes of menopause result in disparate cognitive effects of HT has implications for future research and treatments optimizing HT for menopausal women... - A component of Premarin(®) enhances multiple cognitive functions and influences nicotinic receptor expressionJoshua S Talboom
Department of Psychology, Arizona State University, Tempe, AZ 85287, USA
Horm Behav 58:917-28. 2010.... - Higher levels of estradiol replacement correlate with better spatial memory in surgically menopausal young and middle-aged ratsJoshua S Talboom
Department of Psychology, Arizona State University, Behavioral Neuroscience Division, P O Box 871104, Tempe, AZ 85287, USA
Neurobiol Learn Mem 90:155-63. 2008..Further, there appears to be a distinction between sensitivity to Ovx and responsiveness to ET after Ovx for spatial reference memory performance... - Transitional versus surgical menopause in a rodent model: etiology of ovarian hormone loss impacts memory and the acetylcholine systemJazmin I Acosta
Department of Psychology, Arizona State University, Tempe, Arizona 85287, USA
Endocrinology 150:4248-59. 2009..Collectively, findings suggest that in the rat, initiation of transitional menopause before surgical ovary removal can benefit mnemonic function and could obviate some negative cognitive consequences of surgical menopause alone... - Medroxyprogesterone acetate impairs memory and alters the GABAergic system in aged surgically menopausal ratsB Blair Braden
Department of Psychology, Arizona State University, Tempe, AZ 85287, USA
Neurobiol Learn Mem 93:444-53. 2010..These findings, combined with in vitro evidence that MPA is detrimental to neuronal health, indicates that MPA has negative effects for brain health and function... - Chronic stress impairs prefrontal cortex-dependent response inhibition and spatial working memoryAgnieszka Mika
Department of Psychology, Arizona State University, Tempe, AZ85287 1104, USA
Behav Neurosci 126:605-19. 2012.... - Impact of the hypothalamic-pituitary-adrenal/gonadal axes on trajectory of age-related cognitive declineCheryl D Conrad
Department of Psychology, Arizona State University, Tempe, AZ, USA
Prog Brain Res 182:31-76. 2010....
Research Grants
- Sex differences in factors influencing cognitive agingHeather Bimonte Nelson; Fiscal Year: 2006..After the maze battery, rats from both studies will have neurotrophin levels assayed in cognitive brain regions. ..
- Progesterone, aging, and memory lossHeather Bimonte Nelson; Fiscal Year: 2005..The proposed research will also detail the mnemonic and neural functions that are compromised with age, ovarian hormone loss, and therapies of estrogen alone or estrogen/progesterone combinations. ..
- Variations in Hormone Therapy: Effects on Cognition and Markers of Brain AgingHeather Bimonte Nelson; Fiscal Year: 2007..These studies will help elucidate which variations in hormone therapy attenuate or exacerbate age-related changes in cognition and the brain, as well as the mechanism of progesterone's effects when given alone and with estrogen. ..
- Variations in Hormone Therapy: Effects on Cognition and Markers of Brain AgingHEATHER ALLYSON BIMONTE NELSON; Fiscal Year: 2010..These studies will help elucidate which variations in hormone therapy attenuate or exacerbate age-related changes in cognition and the brain, as well as the mechanism of progesterone's effects when given alone and with estrogen. ..
- Variations in Hormone Therapy: Effects on Cognition and Markers of Brain AgingHeather Bimonte Nelson; Fiscal Year: 2009..These studies will help elucidate which variations in hormone therapy attenuate or exacerbate age-related changes in cognition and the brain, as well as the mechanism of progesterone's effects when given alone and with estrogen. ..